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Aliases for AGAP7P Gene

Aliases for AGAP7P Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene 2 3 5
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 Pseudogene 3 4
  • Centaurin, Gamma-Like Family, Member 4 2 3
  • CTGLF4 3 4
  • AGAP-7 3 4
  • AGAP7 3 4
  • Putative Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 3
  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7 2
  • Centaurin-Gamma-Like Family Member 4 4
  • BA109G10.1 3

External Ids for AGAP7P Gene

Previous HGNC Symbols for AGAP7P Gene

  • CTGLF4
  • AGAP7

Summaries for AGAP7P Gene

GeneCards Summary for AGAP7P Gene

AGAP7P (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene) is a Pseudogene. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is AGAP4.

UniProtKB/Swiss-Prot for AGAP7P Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP7P Gene

Genomics for AGAP7P Gene

Genomic Location for AGAP7P Gene

Chromosome:
10
Start:
46,109,495 bp from pter
End:
46,131,678 bp from pter
Size:
22,184 bases
Orientation:
Plus strand

Genomic View for AGAP7P Gene

Genes around AGAP7P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP7P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP7P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP7P Gene

No data available for Regulatory Elements for AGAP7P Gene

Proteins for AGAP7P Gene

  • Protein details for AGAP7P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VUJ5-AGAP7_HUMAN
    Recommended name:
    Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7
    Protein Accession:
    Q5VUJ5
    Secondary Accessions:
    • A6NGH4

    Protein attributes for AGAP7P Gene

    Size:
    663 amino acids
    Molecular mass:
    73211 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10.

neXtProt entry for AGAP7P Gene

Proteomics data for AGAP7P Gene at MOPED

Post-translational modifications for AGAP7P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for AGAP7P Gene

Domains & Families for AGAP7P Gene

Suggested Antigen Peptide Sequences for AGAP7P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VUJ5

UniProtKB/Swiss-Prot:

AGAP7_HUMAN :
  • Contains 1 Arf-GAP domain.
  • Belongs to the centaurin gamma-like family.
  • Contains 2 ANK repeats.
Domain:
  • Contains 1 Arf-GAP domain.
  • Contains 1 PH domain.
Family:
  • Belongs to the centaurin gamma-like family.
Similarity:
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with AGAP7P: view

Function for AGAP7P Gene

Molecular function for AGAP7P Gene

UniProtKB/Swiss-Prot Function:
Putative GTPase-activating protein.

Phenotypes for AGAP7P Gene

genes like me logo Genes that share phenotypes with AGAP7P: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP7P Gene

Localization for AGAP7P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AGAP7P Gene

Pathways & Interactions for AGAP7P Gene

SuperPathways for AGAP7P Gene

No Data Available

Interacting Proteins for AGAP7P Gene

Gene Ontology (GO) - Biological Process for AGAP7P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AGAP7P Gene

Drugs & Compounds for AGAP7P Gene

No Compound Related Data Available

Transcripts for AGAP7P Gene

mRNA/cDNA for AGAP7P Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP7P Gene

No ASD Table

Relevant External Links for AGAP7P Gene

GeneLoc Exon Structure for
AGAP7P
ECgene alternative splicing isoforms for
AGAP7P

Expression for AGAP7P Gene

mRNA expression in normal human tissues for AGAP7P Gene

Protein differential expression in normal tissues from HIPED for AGAP7P Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AGAP7P Gene



genes like me logo Genes that share expression patterns with AGAP7P: view

Protein tissue co-expression partners for AGAP7P Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for AGAP7P Gene

Orthologs for AGAP7P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP7P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CTGLF2 35
  • 97.94 (n)
  • 95.72 (a)
Species with no ortholog for AGAP7P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP7P Gene

ENSEMBL:
Gene Tree for AGAP7P (if available)
TreeFam:
Gene Tree for AGAP7P (if available)

Paralogs for AGAP7P Gene

Paralogs for AGAP7P Gene

genes like me logo Genes that share paralogs with AGAP7P: view

Variants for AGAP7P Gene

Sequence variations from dbSNP and Humsavar for AGAP7P Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs8213 -- 46,130,578(-) ACGAC(A/G)TATGA nc-transcript-variant
rs1047416 -- 46,130,596(-) GATGC(A/C)TGGGT nc-transcript-variant
rs1060726 -- 46,108,333(+) GACTA(C/G)CTGGG upstream-variant-2KB
rs1064051 -- 46,130,354(-) CCTGC(A/G)CACCC nc-transcript-variant
rs2337714 -- 46,108,348(+) gggcc(A/C)tagtt upstream-variant-2KB

Variation tolerance for AGAP7P Gene

Gene Damage Index Score: 17.70; 98.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AGAP7P Gene

HapMap Linkage Disequilibrium report
AGAP7P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for AGAP7P Gene

Disorders for AGAP7P Gene

Relevant External Links for AGAP7P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AGAP7P

No disorders were found for AGAP7P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP7P Gene

Publications for AGAP7P Gene

  1. The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. (PMID: 25277244) Katsogiannou M. … Rocchi P. (Mol. Cell Proteomics 2014) 3 67

Products for AGAP7P Gene

Sources for AGAP7P Gene

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