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Aliases for AGAP7P Gene

Aliases for AGAP7P Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene 2 3
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 Pseudogene 3 4
  • Centaurin, Gamma-Like Family, Member 4 2 3
  • CTGLF4 3 4
  • AGAP-7 3 4
  • AGAP7 3 4
  • Putative Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 3
  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7 2
  • Centaurin-Gamma-Like Family Member 4 4
  • BA109G10.1 3

External Ids for AGAP7P Gene

Previous Symbols for AGAP7P Gene

  • CTGLF4
  • AGAP7

Summaries for AGAP7P Gene

GeneCards Summary for AGAP7P Gene

AGAP7P (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene) is a Pseudogene. An important paralog of this gene is AGAP4.

UniProtKB/Swiss-Prot for AGAP7P Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP7P Gene

Genomics for AGAP7P Gene

Genomic Location for AGAP7P Gene

Start:
46,109,495 bp from pter
End:
46,131,671 bp from pter
Size:
22,177 bases
Orientation:
Plus strand

Genomic View for AGAP7P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AGAP7P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP7P Gene

No data available for Regulatory Elements for AGAP7P Gene

Proteins for AGAP7P Gene

  • Protein details for AGAP7P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VUJ5-AGAP7_HUMAN
    Recommended name:
    Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7
    Protein Accession:
    Q5VUJ5
    Secondary Accessions:
    • A6NGH4

    Protein attributes for AGAP7P Gene

    Size:
    663 amino acids
    Molecular mass:
    73211 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10

neXtProt entry for AGAP7P Gene

Proteomics data for AGAP7P Gene at MOPED

Post-translational modifications for AGAP7P Gene

No Post-translational modifications

No data available for DME Specific Peptides for AGAP7P Gene

Domains for AGAP7P Gene

Gene Families for AGAP7P Gene

HGNC:
  • PLEKH :Pleckstrin homology (PH) domain containing
  • ArfGAP :ADP-ribosylation factor GTPase activating proteins
  • ANKRD :Ankyrin repeat domain containing

UniProtKB/Swiss-Prot:

AGAP7_HUMAN
Domain:
  • Contains 1 Arf-GAP domain.:
    • Q5VUJ5
  • Contains 1 PH domain.:
    • Q5VUJ5
Family:
  • Belongs to the centaurin gamma-like family.:
    • Q5VUJ5
Similarity:
  • Contains 2 ANK repeats.:
    • Q5VUJ5
genes like me logo Genes that share domains with AGAP7P: view

Function for AGAP7P Gene

Molecular function for AGAP7P Gene

UniProtKB/Swiss-Prot Function: Putative GTPase-activating protein.

Gene Ontology (GO) - Molecular Function for AGAP7P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005096 GTPase activator activity IEA --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with AGAP7P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AGAP7P Gene

Localization for AGAP7P Gene

No data available for Gene Ontology (GO) - Cellular Components for AGAP7P Gene

Pathways for AGAP7P Gene

SuperPathways for AGAP7P Gene

No Data Available

Interacting Proteins for AGAP7P Gene

Gene Ontology (GO) - Biological Process for AGAP7P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043547 positive regulation of GTPase activity IEA --
genes like me logo Genes that share ontologies with AGAP7P: view

No data available for Pathways by source for AGAP7P Gene

Transcripts for AGAP7P Gene

mRNA/cDNA for AGAP7P Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP7P Gene

No ASD Table

Relevant External Links for AGAP7P Gene

GeneLoc Exon Structure for
AGAP7P
ECgene alternative splicing isoforms for
AGAP7P

Expression for AGAP7P Gene

mRNA expression in normal human tissues for AGAP7P Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for AGAP7P Gene

genes like me logo Genes that share expressions with AGAP7P: view

Orthologs for AGAP7P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP7P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CTGLF2 36
  • 97.94 (n)
  • 95.72 (a)
Species with no ortholog for AGAP7P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP7P Gene

ENSEMBL:
Gene Tree for AGAP7P (if available)
TreeFam:
Gene Tree for AGAP7P (if available)

Paralogs for AGAP7P Gene

Paralogs for AGAP7P Gene

genes like me logo Genes that share paralogs with AGAP7P: view

Variants for AGAP7P Gene

Sequence variations from dbSNP and Humsavar for AGAP7P Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs8213 -- 46,130,578(+) ACGAC(A/G)TATGA reference, synonymous-codon
rs1047416 -- 46,130,596(+) GATGC(A/C)TGGGT reference, synonymous-codon
rs1060726 -- 46,108,333(+) GACTA(C/G)CTGGG upstream-variant-2KB
rs2257399 -- 46,108,399(-) GAGAC(A/G)GAGAA upstream-variant-2KB
rs2337714 -- 46,108,348(-) gggcc(A/C)tagtt upstream-variant-2KB

Relevant External Links for AGAP7P Gene

HapMap Linkage Disequilibrium report
AGAP7P

No data available for Structural Variations from Database of Genomic Variants (DGV) for AGAP7P Gene

Disorders for AGAP7P Gene

No disorders were found for AGAP7P Gene.

No data available for UniProtKB/Swiss-Prot for AGAP7P Gene

Publications for AGAP7P Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4

Products for AGAP7P Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate AGAP7P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for AGAP7P
    • Block miRNA regulation of AGAP7P using miScript Target Protectors

    Sources for AGAP7P Gene

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