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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

AGAP3 Gene

protein-coding GIFtS: 49
GCID: GC07P150782

ArfGAP with GTPase domain, ankyrin repeat and PH domain...

(Previous names: centaurin, gamma 3 )
(Previous symbol: CENTG3)

Explore 5 diseases affiliated with
AGAP3 via

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 3¹ ²		MR1-Interacting Protein² ³
CENTG3¹ ² ³		Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 3²
Centaurin, Gamma 3¹ ²		Centaurin-Gamma-3¹
AGAP-3² ³		Cnt-G3¹
CRAG² ³		CRMP (Collapsin Response Mediator Protein) Associated²
MRIP-1² ³		Centaurin-Gamma-3¹
CRAM-Associated GTPase² ³		Cnt-G3¹

External Ids:	HGNC: 16923¹	Entrez Gene: 116988²	Ensembl: ENSG00000133612⁷	UniProtKB: Q96P47³

Export aliases for AGAP3 gene to outside databases

Previous GC identifers: GC07P150415 GC07P144596

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AGAP3_HUMAN, Q96P47

Function: GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in

the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway

Gene Wiki entry for AGAP3 (CENTG3)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the AGAP3 gene promoter:
GR p53 GR-beta GR-alpha C/EBPalpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): AGAP3 promoter sequence

Search SABiosciences Chromatin IP Primers for AGAP3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGAP3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1 Ensembl cytogenetic band: 7q36.1 HGNC cytogenetic band: 7q36.1

AGAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AGAP3 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P150782: view genomic region (about GC identifiers)

Start:	150,782,918 bp from pter	End:	150,841,523 bp from pter
Size:	58,606 bases	Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 150,113,360-150,171,043

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AGAP3_HUMAN, Q96P47 (See protein sequence)

Recommended Name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Size: 875 amino acids; 95044 Da

Subunit: Interacts with PML. Interacts with expanded polyglutamine proteins

Subcellular location: Cytoplasm. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients,

translocates to PML nuclear bodies

1 PDB 3D structure from and Proteopedia for AGAP3:

3IHW (3D)

Secondary accessions: Q59EN0 Q96RK3

Alternative splicing: 4 isoforms: Q96P47-1 Q96P47-2 Q96P47-3 Q96P47-4

Explore the universe of human proteins at neXtProt for AGAP3: NX_Q96P47

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96P47

AGAP3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001036000.1 NP_114152.3

ENSEMBL proteins:

ENSP00000418016 ENSP00000418921 ENSP00000418125 ENSP00000380413 ENSP00000417151

ENSP00000335589 ENSP00000419801 ENSP00000418159 ENSP00000417910

Human Recombinant Protein Products:

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	Browse Proteins at Uscn

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--
GO:0016020	membrane	IEA	--
GO:0071944	cell periphery	IEA	--

AGAP3 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

AGAP3 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR013684 MIRO-like

IPR001849 Pleckstrin_homology

IPR001164 ArfGAP

IPR020849 Small_GTPase_Ras

IPR020683 Ankyrin_rpt-contain_dom

Graphical View of Domain Structure for InterPro Entry Q96P47

ProtoNet protein and cluster: Q96P47

4 Blocks protein families:

IPB001164 HIV Rev interacting protein signature

IPB001849 Pleckstrin-like

IPB002110 Ankyrin repeat signature

IPB013684 Miro-like

UniProtKB/Swiss-Prot: AGAP3_HUMAN, Q96P47

Similarity: Belongs to the centaurin gamma-like family

Similarity: Contains 3 ANK repeats

Similarity: Contains 1 Arf-GAP domain

Similarity: Contains 1 PH domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: AGAP3_HUMAN, Q96P47

Function: GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in

the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway

Enzyme regulation: GTPase activity is stimulated by oxidative stress

miRNA Products:		OriGene 3'-UTR Clone (see all 2): AGAP3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AGAP3
		8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate AGAP3 (see all 43):
		hsa-miR-15a hsa-miR-485-3p hsa-miR-765 hsa-miR-486-3p hsa-miR-29b-1* hsa-miR-424 hsa-miR-629 hsa-miR-3150b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: AGAP3 3' UTR sequence

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGAP3

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	IEA	--
GO:0005525	GTP binding	IEA	--
GO:0005543	phospholipid binding	IEA	--
GO:0008060	ARF GTPase activator activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

AGAP3 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for AGAP3:

Decreased number of cells in m

Decreased viability with pacli

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for AGAP3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/22 Interacting proteins for AGAP3 (Q96P47³ ENSP00000380413⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 22)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GLI2	P10070³	I2D: score=4
AKT3	Q9Y243³	I2D: score=3
ARHGAP1	Q07960³	I2D: score=3
C12orf4	Q9NQ89³	I2D: score=3
CCNA1	P78396³	I2D: score=3

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000060	protein import into nucleus, translocation	IEA	--
GO:0006184	GTP catabolic process	--	--
GO:0007165	signal transduction	--	--
GO:0007264	small GTPase mediated signal transduction	IEA	--
GO:0032312	regulation of ARF GTPase activity	IEA	--

AGAP3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AGAP3
Search CenterWatch for drugs/clinical trials and news about AGAP3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for AGAP3 gene (2 alternative transcripts):

NM_001042535.1 NM_031946.4

Unigene Cluster for AGAP3:

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

Hs.647075 [show with all ESTs]

Unigene Representative Sequence: AL442089

18/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):

ENST00000490097 ENST00000463381(uc003wje.1) ENST00000473312(uc003wjf.1)

ENST00000479901(uc010lpy.1) ENST00000397238(uc003wjg.1 uc003wjj.1)

ENST00000469901 ENST00000476375 ENST00000492234 ENST00000335367(uc003wjh.1)

ENST00000473140 ENST00000490839 ENST00000467724 ENST00000468796 ENST00000480106

ENST00000498559 ENST00000486946 ENST00000475145 ENST00000463179

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AGAP3
		8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate AGAP3 (see all 43):
		hsa-miR-15a hsa-miR-485-3p hsa-miR-765 hsa-miR-486-3p hsa-miR-29b-1* hsa-miR-424 hsa-miR-629 hsa-miR-3150b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: AGAP3 3' UTR sequence

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Additional cDNA sequence:

AB209781.1 AF413079.1 AK027415.1 AK055393.1 AK091771.1 AK096352.1 AL442089.1 BC020426.1

BC037543.1 BC044644.1 BC048300.1

24/31 DOTS entries (see all 31):

DT.100811659 DT.75100587 DT.100058684 DT.121111111 DT.97847223 DT.85102022 DT.87046929 DT.100811656

DT.100811662 DT.97791697 DT.121111038 DT.121111078 DT.40132677 DT.92422879 DT.95130700 DT.100766181

DT.100811661 DT.92422876 DT.121111082 DT.121111103 DT.121111105 DT.100698862 DT.121111060 DT.121111066

24/269 AceView cDNA sequences (see all 269):

AI001048 BC048300 AI831091 AA779405 AI560349 BM669703 AI494590 AI417314

BF528096 AW250867 AI499042 CA428168 BM771305 BM980439 BC044644 AI206287

BC037543 AA135075 BQ086220 AW149429 BF980841 BQ230285 AI470104 CB243944

GeneLoc Exon Structure

5/16 Alternative Splicing Database (ASD) splice patterns (SP) for AGAP3 (see all 16) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	·	10c	·	10d	^	11a	·	11b	^	12a	·	12b	^	13a	·	13b	·	13c	^	14a	·	14b	^
SP1:													-		-		-		-														-		-														-		-
SP2:					-		-		-		-		-		-		-		-														-		-														-		-
SP3:																			-														-		-														-		-
SP4:													-		-		-		-														-		-														-		-
SP5:

ExUns:	15a	·	15b	^	16a	·	16b	^	17a	·	17b	·	17c	^	18	^	19a	·	19b	^	20	^	21	^	22	^	23a	·	23b	^	24	^	25	^	26	^	27a	·	27b
SP1:	-		-		-										-						-						-
SP2:	-		-		-										-						-		-		-		-
SP3:
SP4:
SP5:																					-		-				-

ECgene alternative splicing isoforms for AGAP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

AGAP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAACTTTGT

About this image

AGAP3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See AGAP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AGAP3

SOURCE GeneReport for Unigene cluster: Hs.647075

UniProtKB/Swiss-Prot: AGAP3_HUMAN, Q96P47

Tissue specificity: Widely expressed

SABiosciences Custom PCR Arrays for AGAP3

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGAP3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for AGAP3 gene from 4/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	AGAP3¹	ArfGAP with GTPase domain, ankyrin repeat and PH domain more	76.04(n) 80.37(a)		768507 XM_003640631.1 XP_003640679.1
African clawed frog (Xenopus laevis)	Amphibia	BG813775.1²	--	81.87(n)		BG813775.1
zebrafish (Danio rerio)	Actinopterygii	CT583690.1⁶	--	74(a)	1 ↔ 1	24(35366423-35412751)
fruit fly (Drosophila melanogaster)	Insecta	cenG1A⁶	centaurin gamma 1A	41(a)	1 → many	2L(13835567-13898715)

ENSEMBL Gene Tree for AGAP3 (if available)
TreeFam Gene Tree for AGAP3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for AGAP3 gene

AGAP5² AGAP6² ASAP1² ACAP2² ARAP3² GIT2² ACAP3² ARAP1²

ASAP2² GIT1² ARAP2² AGAP2² AGAP4² AGAP1² AGAP8² ACAP1²

AGAP7² AGAP10² AGAP9² ASAP3²

18/22 SIMAP similar genes for AGAP3 using alignment to 11 protein entries: AGAP3_HUMAN (see all proteins) (see all similar genes):

DKFZp761E2216 CENTG3 CENTG2 AGAP1 AGAP11 AGAP4

AGAP5 AGAP6 AGAP8 AGAP7 CTGLF11P AGAP9

AGAP10 AGAP2 ADAP1 SMAP1 FLJ00312 ARFGAP3

AGAP3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140605909^1,2		--	150782672(+)	`GGTGGC/GGGGGA`	2	--	us2k¹		0	--	--	--	--
rs56353209^1,2	C,	--	150782693(+)	`AGAACT/CGCAGC`	2	--	us2k¹		2		WA	120
rs115336154^1,2	F,	--	150782822(+)	`GGGCTT/CTGGTT`	2	--	us2k¹		1		WA	118
rs114058602^1,2	F,	--	150782884(+)	`TCCCTC/TTTCTT`	2	--	us2k¹		1		WA	118
rs150472213^1,2		--	150782979(+)	`CAGCCC/GGCAGT`	2	--	us2k¹		0	--	--	--	--
rs72617352^1,2	C,	--	150783103(+)	`TAAGCG/AAGGAG`	2	--	us2k¹		3		WA EA	240
rs192682642^1,2		--	150783157(+)	`GCAGCA/GCCCTC`	2	--	us2k¹		0	--	--	--	--
rs200151243^1,2		--	150784001(+)	`GCCCCC/TCCAGC`	4	P L	mis¹		0	--	--	--	--
rs138322898^1,2	C,	--	150784028(+)	`CTCCGC/TGGCCA`	4	A V	mis¹		0	--	--	--	--
rs201792217^1,2		--	150784201(+)	`GTGGCC/TTCTCC`	2	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for AGAP3 (150782918 - 150841523 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for AGAP3
2 CNVs: 70078 4574
5 Indels: 70079 94962 94963 82263 82264

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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AGAP3 for disorders About GeneDecksing

5 diseases for AGAP3: About MalaCards

machado-joseph disease cryptococcosis meningitis malaria

leukemia

2 diseases from the University of Copenhagen DISEASES database for AGAP3:

Cryptococcosis Meningitis

Export disorders for AGAP3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for AGAP3 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with AGAP3)

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A novel GTPase, CRAG, mediates promyelocytic leukemia protein- associated nuclear body formation and degradation of expanded polyglutamine protein. (PubMed id 16461359)^{1, 2} Qin Q.... Yanagi S. (2006)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{1, 2} Beausoleil S.A.... Gygi S.P. (2006)
AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase. (PubMed id 15381706)^{1, 2} Meurer S.... Gross S. (2004)
GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins. (PubMed id 12640130)^{1, 2} Xia C.... Liu M. (2003)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA. (PubMed id 14506264)¹ Surks H.K.... Mendelsohn M.E. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 116988	HGNC: 16923	AceView: CENTG3	Ensembl:ENSG00000133612	euGenes: HUgn116988
ECgene: AGAP3	H-InvDB: AGAP3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for AGAP3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for AGAP3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for AGAP3 gene:
Search GeneIP for patents involving AGAP3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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