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Aliases for AGAP2-AS1 Gene

Subcategory (RNA class) for AGAP2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for AGAP2-AS1 Gene

  • AGAP2 Antisense RNA 1 2 3 5

External Ids for AGAP2-AS1 Gene

Previous GeneCards Identifiers for AGAP2-AS1 Gene

  • GC12P058122
  • GC12P058123

Summaries for AGAP2-AS1 Gene

GeneCards Summary for AGAP2-AS1 Gene

AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for AGAP2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP2-AS1 Gene

Genomics for AGAP2-AS1 Gene

Regulatory Elements for AGAP2-AS1 Gene

Enhancers for AGAP2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H057109 1.5 ENCODE dbSUPER 31.2 -615.0 -614987 3.8 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 SP3 MCM3 MEF2D SSRP1 NEMP1 BAZ2A EEF1AKMT3 ENSG00000257740 SMARCC2 CDK4 CTDSP2 PAN2 ANKRD52 DTX3
GH12H057487 1.4 ENCODE dbSUPER 11.6 -237.6 -237578 2.9 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF766 ZNF416 ZNF207 NEMP1 BAZ2A MBD6 RN7SL809P PRIM1 EEF1AKMT3 CDK4 ENSG00000224713 NAB2 ZBTB39
GH12H057516 1.4 ENCODE dbSUPER 10 -205.2 -205152 8.8 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 SP3 NFYC ZFP41 MEF2D NEMP1 BAZ2A RN7SL809P DTX3 ZBTB39 MBD6 ENSG00000224713 CTDSP2 EEF1AKMT3 DCTN2
GH12H057279 1.3 Ensembl ENCODE 10 -445.9 -445919 2.1 HDGF FOXA2 PKNOX1 ATF1 ARID4B SIN3A GATA2 ZNF143 ZNF207 FOS EEF1AKMT3 NEMP1 PAN2 CDK4 ENSG00000224713 TSPAN31 CTDSP2 LOC283387 SHMT2 NXPH4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for AGAP2-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000052696 360 801 ARID4B SIN3A ZNF2 ZBTB7B GLIS2 ELK1 ZNF143 KLF7 SP3 MXD4

Genomic Locations for AGAP2-AS1 Gene

Genomic Locations for AGAP2-AS1 Gene
2,117 bases
Plus strand

Genomic View for AGAP2-AS1 Gene

Genes around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP2-AS1 Gene

Proteins for AGAP2-AS1 Gene

Post-translational modifications for AGAP2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AGAP2-AS1 Gene

Domains & Families for AGAP2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Function for AGAP2-AS1 Gene

Phenotypes From GWAS Catalog for AGAP2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP2-AS1 Gene

Localization for AGAP2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AGAP2-AS1 Gene

Pathways & Interactions for AGAP2-AS1 Gene

SuperPathways for AGAP2-AS1 Gene

No Data Available

Interacting Proteins for AGAP2-AS1 Gene

Gene Ontology (GO) - Biological Process for AGAP2-AS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for AGAP2-AS1 Gene

Drugs & Compounds for AGAP2-AS1 Gene

No Compound Related Data Available

Transcripts for AGAP2-AS1 Gene

mRNA/cDNA for AGAP2-AS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP2-AS1 Gene

No ASD Table

Relevant External Links for AGAP2-AS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AGAP2-AS1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP2-AS1 Gene

Orthologs for AGAP2-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP2-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia AGAP2-AS1 34
  • 100 (a)
Species where no ortholog for AGAP2-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP2-AS1 Gene

Gene Tree for AGAP2-AS1 (if available)
Gene Tree for AGAP2-AS1 (if available)

Paralogs for AGAP2-AS1 Gene

No data available for Paralogs for AGAP2-AS1 Gene

Variants for AGAP2-AS1 Gene

Sequence variations from dbSNP and Humsavar for AGAP2-AS1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000812250 -- 57,726,177(+) GGGAT(A/T)GTTGA upstream-variant-2KB, utr-variant-3-prime
rs1001238887 -- 57,726,463(+) TCGGA(A/C/G)AGGTG intron-variant, utr-variant-3-prime
rs1002130774 -- 57,725,259(+) AAGGA(C/G)ATGGG upstream-variant-2KB, utr-variant-3-prime
rs1003621192 -- 57,724,857(+) AAGTT(C/G)CTGCT downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1003699616 -- 57,728,249(+) TGCAG(A/G)GGAAG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for AGAP2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv470296 CNV loss 18288195
nsv559045 CNV loss 21841781
nsv826383 CNV gain 20364138

Variation tolerance for AGAP2-AS1 Gene

Gene Damage Index Score: 0.48; 10.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AGAP2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Disorders for AGAP2-AS1 Gene

Relevant External Links for AGAP2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for AGAP2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP2-AS1 Gene

Publications for AGAP2-AS1 Gene

  1. Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. (PMID: 27195672) Li W … Shu Y (Cell death & disease 2016) 2 3 60
  2. Co-expression Network Analysis of Human lncRNAs and Cancer Genes. (PMID: 25392693) Cogill SB … Wang L (Cancer informatics 2014) 2 3 60
  3. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. (PMID: 25739401) Kurian L … Belmonte JCI (Circulation 2015) 3 60
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for AGAP2-AS1 Gene

Sources for AGAP2-AS1 Gene

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