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Aliases for AGAP2-AS1 Gene

Subcategory (RNA class) for AGAP2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for AGAP2-AS1 Gene

  • AGAP2 Antisense RNA 1 2 3 5
  • PUNISHER 3

External Ids for AGAP2-AS1 Gene

Previous GeneCards Identifiers for AGAP2-AS1 Gene

  • GC12P058122
  • GC12P058123

Summaries for AGAP2-AS1 Gene

GeneCards Summary for AGAP2-AS1 Gene

AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP2-AS1 Gene

Genomics for AGAP2-AS1 Gene

Regulatory Elements for AGAP2-AS1 Gene

Enhancers for AGAP2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G057109 1.5 ENCODE dbSUPER 21.2 -615.0 -614987 3.8 CREB3L1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 MCM3 NEMP1 SMARCC2 ENSG00000257740 ANKRD52 BAZ2A NAB2 ENSG00000224713 CTDSP2 LOC283387 RN7SL809P
GH12G057085 1.7 Ensembl ENCODE dbSUPER 11.6 -634.2 -634173 14.1 MLX CREB3L1 AGO1 YBX1 DMAP1 FEZF1 YY1 ZNF143 ZNF416 ZNF263 NEMP1 BAZ2A RN7SL809P NAB2 ANKRD52 ENSG00000258317 ZC3H10 CTDSP2 STAT2 AGAP2-AS1
GH12G057487 1.4 ENCODE dbSUPER 11.6 -237.6 -237578 2.9 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF766 ZNF416 NAB2 NEMP1 BAZ2A DCTN2 RN7SL809P CTDSP2 AGAP2-AS1 ENSG00000224713 ARHGEF25 ATP23
GH12G057575 0.9 ENCODE 10.2 -149.6 -149580 1.4 TBP FOXA2 ARID4B ZNF48 RARA SLC30A9 GATA4 CREM THAP11 SP5 DTX3 ARHGEF25 ENSG00000224713 SLC26A10 KIF5A DCTN2 B4GALNT1 DDIT3 MBD6 MIR616
GH12G057207 0.8 dbSUPER 11.4 -517.5 -517473 2.7 ZNF76 FEZF1 ZNF2 ZNF121 KLF7 ZNF202 ZNF426 ZNF398 ZNF518A ZNF781 NEMP1 RBMS2 RNU6-343P CTDSP2 RN7SL809P ENSG00000224713 TSPAN31 ENSG00000257740 AGAP2-AS1 BAZ2A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for AGAP2-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000052696 360 801 ARID4B SIN3A ZNF2 ZBTB7B GLIS2 ELK1 ZNF143 KLF7 ZNF263 SP3

Genomic Location for AGAP2-AS1 Gene

Chromosome:
12
Start:
57,726,240 bp from pter
End:
57,728,356 bp from pter
Size:
2,117 bases
Orientation:
Plus strand

Genomic View for AGAP2-AS1 Gene

Genes around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP2-AS1 Gene

Proteins for AGAP2-AS1 Gene

Post-translational modifications for AGAP2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AGAP2-AS1 Gene

Domains & Families for AGAP2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Function for AGAP2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP2-AS1 Gene

Localization for AGAP2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AGAP2-AS1 Gene

Pathways & Interactions for AGAP2-AS1 Gene

SuperPathways for AGAP2-AS1 Gene

No Data Available

Interacting Proteins for AGAP2-AS1 Gene

Gene Ontology (GO) - Biological Process for AGAP2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AGAP2-AS1 Gene

Drugs & Compounds for AGAP2-AS1 Gene

No Compound Related Data Available

Transcripts for AGAP2-AS1 Gene

mRNA/cDNA for AGAP2-AS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP2-AS1 Gene

No ASD Table

Relevant External Links for AGAP2-AS1 Gene

GeneLoc Exon Structure for
AGAP2-AS1
ECgene alternative splicing isoforms for
AGAP2-AS1

Expression for AGAP2-AS1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP2-AS1 Gene

Orthologs for AGAP2-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP2-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AGAP2-AS1 35
  • 100 (a)
OneToOne
Species where no ortholog for AGAP2-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP2-AS1 Gene

ENSEMBL:
Gene Tree for AGAP2-AS1 (if available)
TreeFam:
Gene Tree for AGAP2-AS1 (if available)

Paralogs for AGAP2-AS1 Gene

No data available for Paralogs for AGAP2-AS1 Gene

Variants for AGAP2-AS1 Gene

Sequence variations from dbSNP and Humsavar for AGAP2-AS1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000812250 -- 57,726,177(+) GGGAT(A/T)GTTGA upstream-variant-2KB, utr-variant-3-prime
rs1001238887 -- 57,726,463(+) TCGGA(A/C/G)AGGTG intron-variant, utr-variant-3-prime
rs1002130774 -- 57,725,259(+) AAGGA(C/G)ATGGG upstream-variant-2KB, utr-variant-3-prime
rs1003621192 -- 57,724,857(+) AAGTT(C/G)CTGCT downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1003699616 -- 57,728,249(+) TGCAG(A/G)GGAAG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for AGAP2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv470296 CNV loss 18288195
nsv559045 CNV loss 21841781
nsv826383 CNV gain 20364138

Variation tolerance for AGAP2-AS1 Gene

Gene Damage Index Score: 0.48; 10.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AGAP2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AGAP2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Disorders for AGAP2-AS1 Gene

Relevant External Links for AGAP2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AGAP2-AS1

No disorders were found for AGAP2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP2-AS1 Gene

Publications for AGAP2-AS1 Gene

  1. Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. (PMID: 27195672) Li W. … Shu Y. (Cell Death Dis 2016) 2 3 64
  2. Co-expression Network Analysis of Human lncRNAs and Cancer Genes. (PMID: 25392693) Cogill S.B. … Wang L. (Cancer Inform 2014) 2 3 64
  3. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. (PMID: 25739401) Kurian L. … Izpisua Belmonte J.C. (Circulation 2015) 3 64
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for AGAP2-AS1 Gene

Sources for AGAP2-AS1 Gene

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