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Aliases for AGAP11 Gene

Aliases for AGAP11 Gene

  • Ankyrin Repeat And GTPase Domain Arf GTPase Activating Protein 11 2 3
  • AGAP-11 3 4
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 11 3
  • Centaurin-Gamma-Like Protein KIAA1975 4
  • KIAA1975 4

External Ids for AGAP11 Gene

Previous GeneCards Identifiers for AGAP11 Gene

  • GC10P088720
  • GC10P082584

Summaries for AGAP11 Gene

GeneCards Summary for AGAP11 Gene

AGAP11 (Ankyrin Repeat And GTPase Domain Arf GTPase Activating Protein 11) is a Protein Coding gene. GO annotations related to this gene include phospholipid binding. An important paralog of this gene is LOC101060581.

UniProtKB/Swiss-Prot for AGAP11 Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP11 Gene

Genomics for AGAP11 Gene

Regulatory Elements for AGAP11 Gene

Genomic Location for AGAP11 Gene

86,970,741 bp from pter
87,010,203 bp from pter
39,463 bases
Plus strand

Genomic View for AGAP11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AGAP11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP11 Gene

Proteins for AGAP11 Gene

  • Protein details for AGAP11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11
    Protein Accession:
    Secondary Accessions:
    • B9EIP7
    • D3DWE4

    Protein attributes for AGAP11 Gene

    550 amino acids
    Molecular mass:
    60549 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB85561.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for AGAP11 Gene

Proteomics data for AGAP11 Gene at MOPED

Post-translational modifications for AGAP11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for AGAP11 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for AGAP11 Gene

Domains for AGAP11 Gene

Gene Families for AGAP11 Gene

Suggested Antigen Peptide Sequences for AGAP11 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Arf-GAP domain.
  • Belongs to the centaurin gamma-like family.
  • Contains 2 ANK repeats.
  • Contains 1 Arf-GAP domain.
  • Contains 1 PH domain.
  • Belongs to the centaurin gamma-like family.
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with AGAP11: view

Function for AGAP11 Gene

Molecular function for AGAP11 Gene

UniProtKB/Swiss-Prot Function:
Putative GTPase-activating protein.

Gene Ontology (GO) - Molecular Function for AGAP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005096 GTPase activator activity IEA --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with AGAP11: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for AGAP11

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AGAP11 Gene

Localization for AGAP11 Gene

Subcellular locations from

Jensen Localization Image for AGAP11 Gene COMPARTMENTS Subcellular localization image for AGAP11 gene
Compartment Confidence
cytosol 3
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for AGAP11 Gene

Pathways for AGAP11 Gene

SuperPathways for AGAP11 Gene

No Data Available

Interacting Proteins for AGAP11 Gene

Gene Ontology (GO) - Biological Process for AGAP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043547 positive regulation of GTPase activity IEA --
genes like me logo Genes that share ontologies with AGAP11: view

No data available for Pathways by source for AGAP11 Gene

Transcripts for AGAP11 Gene

mRNA/cDNA for AGAP11 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(267) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AGAP11 Gene

Ankyrin repeat and GTPase domain Arf GTPase activating protein 11:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for AGAP11

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP11 Gene

No ASD Table

Relevant External Links for AGAP11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AGAP11 Gene

mRNA expression in normal human tissues for AGAP11 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for AGAP11 Gene

SOURCE GeneReport for Unigene cluster for AGAP11 Gene Hs.511787

genes like me logo Genes that share expressions with AGAP11: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for AGAP11 Gene

Orthologs for AGAP11 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP11 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CTGLF2 35
  • 97.7 (n)
  • 95.25 (a)
Species with no ortholog for AGAP11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP11 Gene

Gene Tree for AGAP11 (if available)
Gene Tree for AGAP11 (if available)

Paralogs for AGAP11 Gene

Paralogs for AGAP11 Gene

(17) SIMAP similar genes for AGAP11 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with AGAP11: view

Variants for AGAP11 Gene

Sequence variations from dbSNP and Humsavar for AGAP11 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1240369 -- 86,997,678(+) TAAAC(C/T)GGTAG intron-variant
rs1240370 -- 86,998,560(+) TTACC(C/T)GGTAG intron-variant
rs1240371 -- 86,998,729(+) AACCC(C/G)GTCTA intron-variant
rs1240372 -- 86,999,094(+) GGGGT(C/T)GGGAC intron-variant
rs1240373 -- 87,000,265(+) AAGGA(C/G)GTATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AGAP11 Gene

Variant ID Type Subtype PubMed ID
dgv310e1 CNV Complex 17122850
dgv311e1 CNV Complex 17122850
dgv312e1 CNV Complex 17122850
nsv428236 CNV Loss 18775914
nsv517487 CNV Gain+Loss 19592680
nsv470969 CNV Loss 18288195
nsv895858 CNV Loss 21882294
essv23924 CNV CNV 17122850
dgv313e1 CNV Complex 17122850
dgv314e1 CNV Complex 17122850
dgv797n71 CNV Loss 21882294
esv27213 CNV Loss 19812545
nsv831939 CNV Gain 17160897
nsv8712 CNV Loss 18304495
esv2664328 CNV Deletion 23128226

Relevant External Links for AGAP11 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP11 Gene

Disorders for AGAP11 Gene

No disorders were found for AGAP11 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for AGAP11 Gene

Publications for AGAP11 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for AGAP11 Gene

Sources for AGAP11 Gene

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