Aliases for AGAP1 Gene
External Ids for AGAP1 Gene
Previous HGNC Symbols for AGAP1 Gene
Previous GeneCards Identifiers for AGAP1 Gene
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for AGAP1 Gene
AGAP1 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1) is a Protein Coding gene. Among its related pathways are Endocytosis. GO annotations related to this gene include GTP binding and phospholipid binding. An important paralog of this gene is AGAP3.
UniProtKB/Swiss-Prot for AGAP1 Gene
GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.