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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AFM Gene

protein-coding   GIFtS: 51
GCID: GC04P074336

afamin
 Explore 10 diseases affiliated with
AFM via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for AFM    

Aliases
for AFM gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Afamin1     Alpha-Alb3
ALB21 2 3 5     Alpha-Albumin1
ALBA1 2 3 5     Alpha-Alb3
ALF2     Alpha-Albumin1

External Ids:    HGNC: 3161   Entrez Gene: 1732   Ensembl: ENSG000000795577   OMIM: 1041455   UniProtKB: P436523   

Export aliases for AFM gene to outside databases

Previous GC identifers: GC04P074587 GC04P074748 GC04P074813 GC04P074712 GC04P074566 GC04P070158


Summaries
for AFM gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for AFM:
This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a
tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be
evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and
secreted into the bloodstream. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
Function: Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein
system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier (By
similarity)

Gene Wiki entry for AFM (Afamin)


Genomic Views
for AFM gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_022778.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AFM gene promoter:
         C/EBPbeta   FOXO3   CUTL1   FOXO3b   Evi-1   Nkx6-1   FOXO3a   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: AFM promoter sequence
   Search SABiosciences Chromatin IP Primers for AFM

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AFM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

AFM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AFM gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P074336:  view genomic region     (about GC identifiers)

Start:
 74,347,400 bp from pter      End:
 74,369,718 bp from pter
Size:
 22,319 bases      Orientation:
 plus strand

Proteins
for AFM gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652 (See protein sequence)
Recommended Name: Afamin precursor  
Size: 599 amino acids; 69069 Da
Subcellular location: Secreted
Secondary accessions: A8K3E1 Q32MR3 Q4W5C5

Explore the universe of human proteins at neXtProt for AFM: NX_P43652

Post-translational modifications:

  • N-glycosylated; more than 90% of the glycans are sialylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P43652

    • AFM Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001124.1  
    ENSEMBL proteins: 
     ENSP00000226355  

    Human Recombinant Protein Products: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for AFM

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS7517938
    GO:0005615extracellular space IDA15952736


    AFM for ontologies           About GeneDecksing



    AFM Antibody Products: 
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    Uscn Antibodies for AFM
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    Uscn ELISAs and CLIAs for AFM

    Protein Domains /
    Families
    for AFM gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    AFM for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR020858 Serum_albumin-like
     IPR000264 Serum_albumin
     IPR001703 Alpha-fetoprotein
     IPR014760 Serum_albumin_N
     IPR020857 Serum_albumin_CS

    Graphical View of Domain Structure for InterPro Entry P43652

    ProtoNet protein and cluster: P43652

    1 Blocks protein family: IPB000264 Serum albumin family

    UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
    Similarity: Belongs to the ALB/AFP/VDB family
    Similarity: Contains 3 albumin domains


    Function
    for AFM gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
    Function: Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein
    system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier (By
    similarity)

         Genatlas biochemistry entry for AFM:
    afamin,87kDa,albumin superfamily

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AFM
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate AFM:
    hsa-miR-137 hsa-miR-197
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AFM (see all 7)
    OriGene shRNA RFP: AFM
    OriGene siRNA: AFM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AFM

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for AFM

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AFM (see all 3)
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    GenScript: all cDNA clones in your preferred vector: AFM (NM_001133)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AFM 

    Cell Line
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    Search LifeMap BioReagents cell lines for AFM

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AFM

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008431vitamin E binding IDA15952736


    AFM for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for AFM:
     Cell cycle / mitosis defect 

    Animal Models:
         4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Afm):
     behavior/neurological  growth/size  nervous system  other 

    AFM for phenotypes           About GeneDecksing


    Pathways & Interactions
    for AFM gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AFM

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051180vitamin transport IDA19046407


    AFM for ontologies           About GeneDecksing



    Drugs & Compounds
    for AFM gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AFM for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AFM
    3 Novoseek chemical compound relationships for AFM gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    vitamin-e 61.8 16 12463752 (3), 12456077 (3), 15952736 (2), 18094419 (1)
    vitamin d 52.1 9 10400926 (1), 16489915 (1), 19733224 (1), 17654119 (1) (see all 5)
    alpha tocopherol 50.4 18 19046407 (4), 12463752 (1), 12456077 (1)

    Search CenterWatch for drugs/clinical trials and news about AFM / AFAM 

    Transcripts
    for AFM gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for AFM gene: 
    NM_001133.2  

    Unigene Cluster for AFM:

    Afamin
    Hs.168718  [show with all ESTs]
    Unigene Representative Sequence: NM_001133
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000226355(uc003hhb.3) ENST00000505794

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AFM
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate AFM:
    hsa-miR-137 hsa-miR-197
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AFM (see all 7)
    OriGene shRNA RFP: AFM
    OriGene siRNA: AFM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AFM
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AFM
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: AFM (NM_001133)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AFM
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AFM 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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    Additional cDNA sequence: 

    AK290556.1 BC109020.1 BC109021.1 L35498.1 

    6 DOTS entries:

    DT.208928  DT.202804  DT.75100220  DT.91948823  DT.92422309  DT.92422310 

    24/31 AceView cDNA sequences (see all 31):

    L35486 BX103962 AI247575 L35497 CB157386 BX110719 AW235536 BF197337 
    NM_001133 BF434245 AA878846 CB162042 AH003117 T67570 AW051948 AA706914 
    L35498 AI492289 AI671722 L32140 T67409 AI670879 AV694104 BF511963 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for AFM    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16
    SP1:                    -                                   -                                                               
    SP2:                                                                                                                        
    SP3:                                                                                                                        
    SP4:                                                                          -                                             


    ECgene alternative splicing isoforms for AFM

    Expression
    for AFM gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AFM expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACTCACAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    AFM expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Gut TubeMidgutGut Tube
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See AFM Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AFM

    SOURCE GeneReport for Unigene cluster: Hs.168718

    UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
    Tissue specificity: High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal
    fluids (at protein level)

        SABiosciences Custom PCR Arrays for AFM
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    In Situ
    Assay Products:     
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    Orthologs
    for AFM gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for AFM gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Afm1 , 5 afamin1, 5 76.96(n)1
    67.78(a)1    		   5 (44.78 cM)5
    2806621  NM_145146.21  NP_660128.21 
     905189325 
    chicken
    (Gallus gallus)    		 Aves --
    		 Uncharacterized protein
    		 34(a)
    		 1 → many
    		 4(52369802-52381338)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 33(a)
    33(a)
    		 many ↔ many
    many ↔ many
    		 GL343253.1(499069-512404)
    GL343253.1(478702-490825)
    zebrafish
    (Danio rerio)    		 Actinopterygii gc6
    		 group-specific component (vitamin D binding protei...
    		 20(a)
    		 1 → many
    		 5(47282879-47303096)


    ENSEMBL Gene Tree for AFM (if available)
    TreeFam Gene Tree for AFM (if available) 

    Paralogs
    for AFM gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AFM gene
    ALB2  GC2  AFP2  
    2 SIMAP similar genes for AFM using alignment to 1 protein entry:     AFAM_HUMAN:
    AFP    ALB

    AFM for paralogs           About GeneDecksing



    Genomic Variants
    for AFM gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AFM
    DNA2.0 Custom Variant and Variant Library Synthesis for AFM

    Disorders / Diseases
    for AFM gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    AFM for disorders           About GeneDecksing

    OMIM gene information: 104145    OMIM disorders: --

    10 diseases for AFM:    About MalaCards
    congenital disorder of glycosylation    squamous papillomatosis    trigonitis    squamous cell carcinoma
    down syndrome    endometriosis    ovarian cancer    peritonitis
    carcinoma    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for AFM:
    Squamous papillomatosis     Trigonitis

    Export disorders for AFM gene to outside databases

    Publications
    for AFM gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AFM gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with AFM)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family. (PubMed id 7517938)1, 2, 3, 9 Lichenstein H.S....Zukowski M.M. (1994)
    2. Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. (PubMed id 15952736)1, 2, 9 Jerkovic L....Dieplinger H. (2005)
    3. Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier. (PubMed id 19046407)1, 2, 9 Kratzer I....Sattler W. (2009)
    4. Characterization of the vitamin E-binding properties of human plasma afamin. (PubMed id 12463752)1, 2, 9 Voegele A.F....Dieplinger H. (2002)
    5. Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family. (PubMed id 8755513)1, 2, 9 Nishio H. and Dugaiczyk A. (1996)
    6. Identification of rat alpha-albumin and cDNA cloning of its human ortholog. (PubMed id 7875606)1, 2, 9 Allard D.... Belanger L. (1995)
    7. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (2006)
    8. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    9. Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. (PubMed id 14760718)1, 2 Bunkenborg J.... Wisniewski J.R. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    External Searches for AFM gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing AFM gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 173 HGNC: 316 AceView: AFM Ensembl:ENSG00000079557 euGenes: HUgn173
    ECgene: AFM H-InvDB: AFM

    Other Databases showing AFM gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing AFM gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AFM Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for AFM gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for AFM gene:
    Search GeneIP for patents involving AFM

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
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     EMD Millipore Custom Antibody & Bulk Services
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     OriGene Antibodies for AFM   OriGene shRNA RFP for AFM  
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AFM
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     Regulatory tfbs in AFM promoter
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
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     AFM Proteins, Antibodies, CLIAs, and ELISAs
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for AFM
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     ThermoFisher Antibodies for AFM
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AFM
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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    von Willebrand factor
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