Aliases for AFG3L2 Gene
External Ids for AFG3L2 Gene
Previous Symbols for AFG3L2 Gene
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008]
GeneCards Summary for AFG3L2 Gene
AFG3L2 (AFG3-Like AAA ATPase 2) is a Protein Coding gene. Diseases associated with AFG3L2 include spinocerebellar ataxia 28 and early-onset spastic ataxia-neuropathy syndrome. GO annotations related to this gene include metalloendopeptidase activity and nucleoside-triphosphatase activity.
UniProtKB/Swiss-Prot for AFG3L2 Gene
ATP-dependent protease which is essential for axonal development.