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Aliases for AFG3L1P Gene

Aliases for AFG3L1P Gene

  • AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene 2 3 5
  • AFG3 Like AAA ATPase 1, Pseudogene 2 3
  • AFG3 ATPase Family Gene 3-Like 1 (S. Cerevisiae), Pseudogene 2
  • AFG3 ATPase Family Member 3-Like 1, Pseudogene 3
  • AFG3 ATPase Family Gene 3-Like 1, Pseudogene 3
  • AFG3 (ATPase Family Gene 3, Yeast)-Like 1 3
  • AFG3L1 3
  • AFG3 3

External Ids for AFG3L1P Gene

Previous HGNC Symbols for AFG3L1P Gene

  • AFG3
  • AFG3L1

Previous GeneCards Identifiers for AFG3L1P Gene

  • GC16P090039
  • GC16P090041

Summaries for AFG3L1P Gene

GeneCards Summary for AFG3L1P Gene

AFG3L1P (AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AFG3L1P Gene

Genomics for AFG3L1P Gene

Regulatory Elements for AFG3L1P Gene

Enhancers for AFG3L1P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G089993 1.6 Ensembl ENCODE dbSUPER 58.1 +22.7 22668 3.5 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 ARID4B SIN3A ZNF2 ZBTB7B ENSG00000259877 AFG3L1P MC1R LINC00304 SPG7 DBNDD1 LOC101927863 GAS8 SNORD68 URAHP
GH16G089558 1.7 Ensembl ENCODE dbSUPER 26.1 -410.0 -409955 7.9 CREB3L1 MLX AGO1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC ENSG00000259877 RPL13 AFG3L1P MC1R SPG7 LINC00304 CTU2 LOC101927863 CDK10 SNORD68
GH16G089440 1.9 FANTOM5 Ensembl ENCODE dbSUPER 17.6 -529.7 -529698 5.8 HNRNPUL1 PKNOX1 FOXA2 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SPG7 ENSG00000268218 RPL13 AFG3L1P MC1R DBNDD1 ZNF778 SNORD68 ENSG00000260279 LOC101927863
GH16G089503 1.8 FANTOM5 ENCODE dbSUPER 17.7 -465.6 -465597 6.1 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 RPL13 SPG7 SNORD68 ENSG00000268218 AFG3L1P MC1R RNU6-430P ENSG00000260279 ZNF778 LOC101927863
GH16G089825 1.6 FANTOM5 ENCODE dbSUPER 17.7 -144.3 -144272 5.2 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 CDK10 FANCA SPIRE2 AFG3L1P SPG7 MC1R ENSG00000268218 ENSG00000260279 LOC101927863 LOC105371419
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AFG3L1P on UCSC Golden Path with GeneCards custom track

Promoters for AFG3L1P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000089801 320 1401 HDGF HNRNPUL1 MLX CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for AFG3L1P Gene

Chromosome:
16
Start:
89,972,580 bp from pter
End:
90,002,161 bp from pter
Size:
29,582 bases
Orientation:
Plus strand

Genomic View for AFG3L1P Gene

Genes around AFG3L1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AFG3L1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AFG3L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFG3L1P Gene

Proteins for AFG3L1P Gene

Post-translational modifications for AFG3L1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFG3L1P Gene

Domains & Families for AFG3L1P Gene

Gene Families for AFG3L1P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AFG3L1P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AFG3L1P Gene

Function for AFG3L1P Gene

genes like me logo Genes that share phenotypes with AFG3L1P: view

Animal Model Products

  • Taconic Biosciences Mouse Models for AFG3L1P

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AFG3L1P Gene

Localization for AFG3L1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AFG3L1P Gene

Pathways & Interactions for AFG3L1P Gene

SuperPathways for AFG3L1P Gene

No Data Available

Interacting Proteins for AFG3L1P Gene

Gene Ontology (GO) - Biological Process for AFG3L1P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AFG3L1P Gene

Drugs & Compounds for AFG3L1P Gene

No Compound Related Data Available

Transcripts for AFG3L1P Gene

Unigene Clusters for AFG3L1P Gene

AFG3 ATPase family member 3-like 1 (S. cerevisiae), pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AFG3L1P Gene

No ASD Table

Relevant External Links for AFG3L1P Gene

GeneLoc Exon Structure for
AFG3L1P
ECgene alternative splicing isoforms for
AFG3L1P

Expression for AFG3L1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AFG3L1P Gene

NURSA nuclear receptor signaling pathways regulating expression of AFG3L1P Gene:

AFG3L1P

SOURCE GeneReport for Unigene cluster for AFG3L1P Gene:

Hs.534773
genes like me logo Genes that share expression patterns with AFG3L1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AFG3L1P Gene

Orthologs for AFG3L1P Gene

Evolution for AFG3L1P Gene

ENSEMBL:
Gene Tree for AFG3L1P (if available)
TreeFam:
Gene Tree for AFG3L1P (if available)

No data available for Orthologs for AFG3L1P Gene

Paralogs for AFG3L1P Gene

No data available for Paralogs for AFG3L1P Gene

Variants for AFG3L1P Gene

Sequence variations from dbSNP and Humsavar for AFG3L1P Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000102112 -- 89,997,657(+) GTGAT(C/G)TCGGC intron-variant
rs1000300510 -- 89,997,607(+) TTTTT(G/T)GAGAC intron-variant
rs1000353797 -- 89,981,993(+) GATGC(C/T)CTTAA intron-variant
rs1000464059 -- 89,972,592(+) TTGCG(C/T)ATGCG nc-transcript-variant, utr-variant-5-prime
rs1000492851 -- 89,976,555(+) GTATG(C/T)GTGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AFG3L1P Gene

Variant ID Type Subtype PubMed ID
esv2136699 CNV deletion 18987734
esv2664835 CNV deletion 23128226
esv2762221 CNV gain+loss 21179565
esv3639603 CNV gain 21293372
esv3639604 CNV loss 21293372
esv3639605 CNV loss 21293372
esv3689 CNV loss 18987735
esv3892941 CNV gain 25118596
nsv103059 CNV insertion 16902084
nsv103116 CNV deletion 16902084
nsv1066499 CNV loss 25217958
nsv428331 CNV gain+loss 18775914
nsv457626 CNV loss 19166990
nsv471119 CNV loss 18288195
nsv471120 CNV gain 18288195
nsv477114 CNV novel sequence insertion 20440878
nsv479100 CNV novel sequence insertion 20440878
nsv482951 CNV loss 15286789
nsv573799 CNV gain 21841781
nsv573810 CNV loss 21841781
nsv573841 CNV loss 21841781
nsv573842 CNV loss 21841781
nsv952080 CNV deletion 24416366

Relevant External Links for AFG3L1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AFG3L1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AFG3L1P Gene

Disorders for AFG3L1P Gene

Relevant External Links for AFG3L1P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AFG3L1P

No disorders were found for AFG3L1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AFG3L1P Gene

Publications for AFG3L1P Gene

  1. Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein. (PMID: 11549317) Kremmidiotis G. … Callen D.F. (Genomics 2001) 2 3 22 64
  2. Chromosomal locations of three human nuclear genes (RPSM12, TUFM, and AFG3L1) specifying putative components of the mitochondrial gene expression apparatus. (PMID: 9545647) Shah Z.H. … Jacobs H.T. (Genomics 1998) 2 3 22 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz H.J. … Yaspo M.L. (J. Biol. Chem. 2011) 3 64
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64

Products for AFG3L1P Gene

Sources for AFG3L1P Gene

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