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Aliases for AFG3L1P Gene

Aliases for AFG3L1P Gene

  • AFG3-Like AAA ATPase 1, Pseudogene 2 3
  • AFG3 ATPase Family Member 3-Like 1 (S. Cerevisiae), Pseudogene 2
  • AFG3 ATPase Family Gene 3-Like 1 (S. Cerevisiae), Pseudogene 2
  • AFG3 ATPase Family Member 3-Like 1, Pseudogene 3
  • AFG3 ATPase Family Gene 3-Like 1, Pseudogene 3
  • AFG3 (ATPase Family Gene 3, Yeast)-Like 1 3
  • AFG3L1 3
  • AFG3 3

External Ids for AFG3L1P Gene

Previous HGNC Symbols for AFG3L1P Gene

  • AFG3
  • AFG3L1

Previous GeneCards Identifiers for AFG3L1P Gene

  • GC16P090039
  • GC16P090041

Summaries for AFG3L1P Gene

GeneCards Summary for AFG3L1P Gene

AFG3L1P (AFG3-Like AAA ATPase 1, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AFG3L1P Gene

Genomics for AFG3L1P Gene

Genomic Location for AFG3L1P Gene

89,972,580 bp from pter
90,002,161 bp from pter
29,582 bases
Plus strand

Genomic View for AFG3L1P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AFG3L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFG3L1P Gene

No data available for Regulatory Elements for AFG3L1P Gene

Proteins for AFG3L1P Gene

Post-translational modifications for AFG3L1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFG3L1P Gene

Domains & Families for AFG3L1P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AFG3L1P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AFG3L1P Gene

Function for AFG3L1P Gene

genes like me logo Genes that share phenotypes with AFG3L1P: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for AFG3L1P Gene

Localization for AFG3L1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AFG3L1P Gene

Pathways & Interactions for AFG3L1P Gene

SuperPathways for AFG3L1P Gene

No Data Available

Interacting Proteins for AFG3L1P Gene

Gene Ontology (GO) - Biological Process for AFG3L1P Gene


No data available for Pathways by source and SIGNOR curated interactions for AFG3L1P Gene

Drugs & Compounds for AFG3L1P Gene

No Compound Related Data Available

Transcripts for AFG3L1P Gene

Unigene Clusters for AFG3L1P Gene

AFG3 ATPase family member 3-like 1 (S. cerevisiae), pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AFG3L1P Gene

No ASD Table

Relevant External Links for AFG3L1P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AFG3L1P Gene

mRNA expression in normal human tissues for AFG3L1P Gene

SOURCE GeneReport for Unigene cluster for AFG3L1P Gene Hs.534773

genes like me logo Genes that share expression patterns with AFG3L1P: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for AFG3L1P Gene

Orthologs for AFG3L1P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for AFG3L1P Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Afg3l1 16
Species with no ortholog for AFG3L1P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AFG3L1P Gene

Gene Tree for AFG3L1P (if available)
Gene Tree for AFG3L1P (if available)

Paralogs for AFG3L1P Gene

No data available for Paralogs for AFG3L1P Gene

Variants for AFG3L1P Gene

Sequence variations from dbSNP and Humsavar for AFG3L1P Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3803683 -- 89,993,873(-) TGAGC(A/G)CTGCC nc-transcript-variant
rs3803684 -- 89,979,965(-) CTGTT(A/G)TTAGG intron-variant
rs3923703 -- 89,975,895(+) CACAG(C/T)CTTTA intron-variant
rs4238832 -- 89,983,853(+) AGTTC(C/T)GGAAG intron-variant
rs4238833 -- 89,984,281(+) GCCAG(G/T)CTAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AFG3L1P Gene

Variant ID Type Subtype PubMed ID
nsv428331 CNV Gain+Loss 18775914
dgv3009n71 CNV Loss 21882294
nsv907429 CNV Loss 21882294
dgv3015n71 CNV Loss 21882294
nsv907443 CNV Loss 21882294
nsv907445 CNV Loss 21882294
nsv457626 CNV Loss 19166990
nsv471119 CNV Loss 18288195
nsv482951 CNV Loss 15286789
nsv471120 CNV Gain 18288195
esv2136699 CNV Deletion 18987734
esv3689 CNV Deletion 18987735
nsv103116 CNV Loss 16902084
esv2664835 CNV Deletion 23128226
nsv103059 CNV Insertion 16902084
dgv3016n71 CNV Loss 21882294

Relevant External Links for AFG3L1P Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AFG3L1P Gene

Disorders for AFG3L1P Gene

Relevant External Links for AFG3L1P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with AFG3L1P: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AFG3L1P Gene

Publications for AFG3L1P Gene

  1. Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein. (PMID: 11549317) Kremmidiotis G. … Callen D.F. (Genomics 2001) 2 23 67
  2. Chromosomal locations of three human nuclear genes (RPSM12, TUFM, and AFG3L1) specifying putative components of the mitochondrial gene expression apparatus. (PMID: 9545647) Shah Z.H. … Jacobs H.T. (Genomics 1998) 2 23 67
  3. Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. (PMID: 20038678) Ehses S. … Langer T. (J. Cell Biol. 2009) 23 67
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  5. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz H.J. … Yaspo M.L. (J. Biol. Chem. 2011) 67

Products for AFG3L1P Gene

Sources for AFG3L1P Gene

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