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Aliases for AFDN-AS1 Gene

Subcategory (RNA class) for AFDN-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for AFDN-AS1 Gene

  • AFDN Antisense RNA 1 (Head To Head) 2 3 5
  • MLLT4 Antisense RNA 1 (Non-Protein Coding) 2 3
  • MLLT4 Antisense RNA 1 (Head To Head) 2 3
  • C6orf124 3 4
  • Chromosome 6 Open Reading Frame 124 2
  • AFDN Antisense Gene Protein 1 4
  • AFDN Antisense RNA 1 4
  • Protein HGC6.4 4
  • DJ431P23.3 3
  • MLLT4-AS1 3
  • HGC6.4 3

External Ids for AFDN-AS1 Gene

Previous HGNC Symbols for AFDN-AS1 Gene

  • C6orf124
  • MLLT4-AS1

Summaries for AFDN-AS1 Gene

GeneCards Summary for AFDN-AS1 Gene

AFDN-AS1 (AFDN Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AFDN-AS1 Gene

Genomics for AFDN-AS1 Gene

Regulatory Elements for AFDN-AS1 Gene

Enhancers for AFDN-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G167102 1.5 Ensembl ENCODE dbSUPER 10.6 +723.4 723430 1.7 HDGF ATF1 FOXA2 GLI4 YBX1 TCF12 GATA2 ZNF143 ZNF548 SP5 ENSG00000261420 RNASET2 AFDN-AS1 FGFR1OP LOC105378120 CCR6 GC06M167096
GH06G167805 0.9 ENCODE 12 +20.4 20417 2.3 FOXA2 ATF1 MLX ARID4B DMAP1 ZNF48 SP5 MXD4 MIER2 PPARG AFDN AFDN-AS1 LINC01558
GH06G168314 0.8 ENCODE 10.6 -488.4 -488370 1.3 PKNOX1 ZNF473 ZFP64 GLI4 YBX1 PLRG1 RAD21 ZNF263 ZNF680 ZBTB2 AFDN-AS1 DACT2 LOC105378138
GH06G168312 0.8 ENCODE 10.6 -486.9 -486857 1.6 ELF3 CTCF KLF1 ZNF792 ARNT ZNF473 TSC22D4 NFXL1 YBX1 RAD21 AFDN-AS1 DACT2 LOC105378138
GH06G167782 0.7 ENCODE 11.2 +43.8 43775 1.2 ELF3 SOX13 TFAP4 SAP130 ARID4B ZNF48 ZNF7 TEAD3 FOSL1 GATA2 AFDN AFDN-AS1 LINC02487 LOC441179 LOC100422263
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AFDN-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for AFDN-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000206990 -304 3000 HNRNPUL1 PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for AFDN-AS1 Gene

Chromosome:
6
Start:
167,823,876 bp from pter
End:
167,826,796 bp from pter
Size:
2,921 bases
Orientation:
Minus strand

Genomic View for AFDN-AS1 Gene

Genes around AFDN-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AFDN-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AFDN-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFDN-AS1 Gene

Proteins for AFDN-AS1 Gene

  • Protein details for AFDN-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6Z5-AFAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein AFDN-AS1
    Protein Accession:
    Q9Y6Z5
    Secondary Accessions:
    • B4DW86
    • Q8NB23

    Protein attributes for AFDN-AS1 Gene

    Size:
    254 amino acids
    Molecular mass:
    26128 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for AFDN-AS1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AFDN-AS1 Gene

Post-translational modifications for AFDN-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFDN-AS1 Gene

Domains & Families for AFDN-AS1 Gene

Protein Domains for AFDN-AS1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for AFDN-AS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AFDN-AS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for AFDN-AS1 Gene

Function for AFDN-AS1 Gene

Gene Ontology (GO) - Molecular Function for AFDN-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with AFDN-AS1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AFDN-AS1 Gene

Localization for AFDN-AS1 Gene

Gene Ontology (GO) - Cellular Components for AFDN-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with AFDN-AS1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for AFDN-AS1 Gene

Pathways & Interactions for AFDN-AS1 Gene

SuperPathways for AFDN-AS1 Gene

No Data Available

Interacting Proteins for AFDN-AS1 Gene

Gene Ontology (GO) - Biological Process for AFDN-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with AFDN-AS1: view

No data available for Pathways by source and SIGNOR curated interactions for AFDN-AS1 Gene

Transcripts for AFDN-AS1 Gene

mRNA/cDNA for AFDN-AS1 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AFDN-AS1 Gene

No ASD Table

Relevant External Links for AFDN-AS1 Gene

GeneLoc Exon Structure for
AFDN-AS1
ECgene alternative splicing isoforms for
AFDN-AS1

Expression for AFDN-AS1 Gene

mRNA Expression by UniProt/SwissProt for AFDN-AS1 Gene:

Q9Y6Z5-AFAS1_HUMAN
Tissue specificity: Ubiquitously expressed.

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AFDN-AS1 Gene

Orthologs for AFDN-AS1 Gene

Evolution for AFDN-AS1 Gene

ENSEMBL:
Gene Tree for AFDN-AS1 (if available)
TreeFam:
Gene Tree for AFDN-AS1 (if available)

No data available for Orthologs for AFDN-AS1 Gene

Paralogs for AFDN-AS1 Gene

No data available for Paralogs for AFDN-AS1 Gene

Variants for AFDN-AS1 Gene

Sequence variations from dbSNP and Humsavar for AFDN-AS1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000173567 -- 167,828,154(+) CAATA(C/T)TTGTG intron-variant, upstream-variant-2KB
rs1000225515 -- 167,826,853(+) GCGGC(-/GCGCACGGCGGCGGGCGGG)GCGCG upstream-variant-2KB
rs1000315026 -- 167,828,756(+) GCTTT(C/T)TTTTT intron-variant, upstream-variant-2KB
rs1000456931 -- 167,828,432(+) ACTTG(A/C)CGTGG intron-variant, upstream-variant-2KB
rs1001709834 -- 167,826,640(+) AGCGC(A/G)CGTCC nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for AFDN-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv217e55 CNV gain 17911159
dgv27e196 CNV duplication 17116639
esv2422263 CNV duplication 17116639
esv2761051 CNV gain 21179565
nsv1027114 CNV gain 25217958
nsv1074037 CNV deletion 25765185
nsv830864 CNV gain 17160897
nsv949897 CNV deletion 24416366

Relevant External Links for AFDN-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AFDN-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AFDN-AS1 Gene

Disorders for AFDN-AS1 Gene

Relevant External Links for AFDN-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AFDN-AS1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AFDN-AS1

No disorders were found for AFDN-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AFDN-AS1 Gene

Publications for AFDN-AS1 Gene

  1. Complete DNA sequence and characterization of a 330-kb VNTR-rich region on chromosome 6q27 that is commonly deleted in ovarian cancer. (PMID: 10382971) Minaguchi T. … Nakamura Y. (DNA Res. 1999) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4 64

Products for AFDN-AS1 Gene

Sources for AFDN-AS1 Gene

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