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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

AFAP1L2 Gene

protein-coding GIFtS: 52
GCID: GC10M116045

actin filament associated protein 1-like 2

(Previous name: KIAA1914 )
(Previous symbol: KIAA1914)

Explore 4 diseases affiliated with
AFAP1L2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Actin Filament Associated Protein 1-Like 2¹ ²		Em:AC005383.4¹
KIAA1914¹ ² ³ ⁵		FLJ14564¹
XB130¹ ² ³ ⁵		CTB-1144G6.4²
AFAP1-Like Protein 2² ³		Actin Filament-Associated Protein 1-Like 2²

External Ids:	HGNC: 25901¹	Entrez Gene: 84632²	Ensembl: ENSG00000169129⁷	OMIM: 612420⁵	UniProtKB: Q8N4X5³

Export aliases for AFAP1L2 gene to outside databases

Previous GC identifer: GC10M109682

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AF1L2_HUMAN, Q8N4X5

Function: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated

transcription activation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for AFAP1L2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: AFAP1L2 promoter sequence

Search SABiosciences Chromatin IP Primers for AFAP1L2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AFAP1L2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.3 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q26.11

AFAP1L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AFAP1L2 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M116045: view genomic region (about GC identifiers)

Start:	116,054,583 bp from pter	End:	116,164,515 bp from pter
Size:	109,933 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AF1L2_HUMAN, Q8N4X5 (See protein sequence)

Recommended Name: Actin filament-associated protein 1-like 2

Size: 818 amino acids; 91300 Da

Subunit: Interacts with SRC. Interacts with LCK when tyrosine phosphorylated

Subcellular location: Cytoplasm

Sequence caution: Sequence=BAB67807.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for AFAP1L2:

2COF (3D)

Secondary accessions: A8K6P7 B3KVQ8 Q2UZW3 Q8TB54 Q96PX4 Q96SY5

Alternative splicing: 4 isoforms: Q8N4X5-1 Q8N4X5-2 Q8N4X5-3 Q8N4X5-4

Explore the universe of human proteins at neXtProt for AFAP1L2: NX_Q8N4X5

Post-translational modifications:

Tyrosine phosphorylated (by SRC)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N4X5

AFAP1L2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001001936.1 NP_115939.1

ENSEMBL proteins:

ENSP00000358276 ENSP00000303042 ENSP00000396781 ENSP00000444511

Human Recombinant Protein Products:

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	Novus Biologicals AFAP1L2 Proteins Novus Biologicals AFAP1L2 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for AFAP1L2

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005886	plasma membrane	IDA	--
GO:0016235	aggresome	IDA	--

AFAP1L2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for AFAP1L2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

AFAP1L2 for domains About GeneDecksing

2 InterPro domains/families:

IPR001849 Pleckstrin_homology

IPR011993 PH_like_dom

Graphical View of Domain Structure for InterPro Entry Q8N4X5

ProtoNet protein and cluster: Q8N4X5

1 Blocks protein family: IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: AF1L2_HUMAN, Q8N4X5

Similarity: Contains 2 PH domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: AF1L2_HUMAN, Q8N4X5

Function: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated

transcription activation

miRNA Products:		OriGene 3'-UTR Clone (see all 2): AFAP1L2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AFAP1L2
		8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate AFAP1L2 (see all 20):
		hsa-miR-30c hsa-miR-3607-3p hsa-miR-30d hsa-miR-219-5p hsa-miR-373* hsa-miR-374c hsa-miR-30a hsa-miR-924

		SwitchGear 3'UTR luciferase reporter plasmid: AFAP1L2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AFAP1L2 (see all 4) OriGene shRNA RFP: AFAP1L2 OriGene siRNA: AFAP1L2
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for AFAP1L2

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for AFAP1L2
		Search LifeMap BioReagents cell lines for AFAP1L2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AFAP1L2

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005543	phospholipid binding	IEA	--
GO:0017124	SH3 domain binding	IPI	17412687
GO:0030296	protein tyrosine kinase activator activity	IDA	17412687
GO:0042169	SH2 domain binding	IPI	17412687

AFAP1L2 for ontologies About GeneDecksing

4 GenomeRNAi human phenotypes for AFAP1L2:

Decreased melanin production

Increased S DNA content

Increased cell number in G1, s

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for AFAP1L2

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/8 Interacting proteins for AFAP1L2 (Q8N4X5^{2, 3} ENSP00000303042⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RASA1	P20936³, ENSP00000274376⁴	I2D: score=1 STRING: ENSP00000274376
SRC	P12931³, ENSP00000350941⁴	I2D: score=1 STRING: ENSP00000350941
ACD	ENSP00000377496⁴	STRING: ENSP00000377496
POT1	ENSP00000350249⁴	STRING: ENSP00000350249
TERF1	ENSP00000276603⁴	STRING: ENSP00000276603

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006954	inflammatory response	IDA	17412687
GO:0007346	regulation of mitotic cell cycle	IDA	17412687
GO:0032675	regulation of interleukin-6 production	IDA	17412687
GO:0032757	positive regulation of interleukin-8 production	IDA	17412687
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	IDA	17412687

AFAP1L2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AFAP1L2
Search CenterWatch for drugs/clinical trials and news about AFAP1L2 / AF1L2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for AFAP1L2 gene (2 alternative transcripts):

NM_001001936.1 NM_032550.2

Unigene Cluster for AFAP1L2:

Actin filament associated protein 1-like 2

Hs.501106 [show with all ESTs]

Unigene Representative Sequence: NM_001001936

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000369271(uc001lbn.3 uc001lbo.3 uc010qse.2 uc001lbp.3 uc001lbr.1)

ENST00000304129(uc001lbm.3 uc010qsd.2) ENST00000491814(uc001lbq.1)

ENST00000481462 ENST00000486300 ENST00000419268 ENST00000483496 ENST00000545353

miRNA Products:		OriGene 3'-UTR Clone (see all 2): AFAP1L2 Browse OriGene MicroRNA Expression Plasmids
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		hsa-miR-30c hsa-miR-3607-3p hsa-miR-30d hsa-miR-219-5p hsa-miR-373* hsa-miR-374c hsa-miR-30a hsa-miR-924

		SwitchGear 3'UTR luciferase reporter plasmid: AFAP1L2 3' UTR sequence

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Additional cDNA sequence:

AB067501.1 AF474151.1 AK123108.1 AK291712.1 AK294969.1 AK295538.1 BC016403.1 BC024314.1

BC033212.1 BC035713.1

12 DOTS entries:

DT.444461 DT.101981461 DT.100786979 DT.102828116 DT.210446 DT.95160952 DT.99968703 DT.100698484

DT.121270727 DT.97842381 DT.100753165 DT.100836972

24/93 AceView cDNA sequences (see all 93):

F01902 CD515315 Z38874 NM_032550 BM561567 AA404497 AB067501 CR595409

AI420121 BP342007 CK300428 AI658698 AI420374 CO245655 AI493714 AW006448

BE645538 AK123108 BC016403 BC033212 BM918355 AA570115 BX280240 NM_001001936

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for AFAP1L2 (see all 11) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9a	·	9b	·	9c	^	10a	·	10b	^	11	^	12	^	13	^	14a	·	14b	^	15	^	16a	·	16b	^	17a	·	17b	^
SP1:					-		-				-										-																		-						-
SP2:					-		-				-										-																		-						-
SP3:											-																												-						-
SP4:					-		-				-										-																		-						-
SP5:							-				-										-

ExUns:	18	^	19a	·	19b	^	20a	·	20b	^	21	^	22a	·	22b	·	22c
SP1:									-
SP2:
SP3:									-
SP4:
SP5:

ECgene alternative splicing isoforms for AFAP1L2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

AFAP1L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTTTTGAGA

About this image

AFAP1L2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

PureStem™ progenitor EN7 (Embryonic Progenitor Cell)

PureStem™ progenitor W10 (Embryonic Progenitor Cell)

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See AFAP1L2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AFAP1L2

SOURCE GeneReport for Unigene cluster: Hs.501106

UniProtKB/Swiss-Prot: AF1L2_HUMAN, Q8N4X5

Tissue specificity: Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas

SABiosciences Custom PCR Arrays for AFAP1L2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AFAP1L2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for AFAP1L2 gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	AFAP1L2¹	actin filament associated protein 1-like 2	71.74(n) 73.78(a)		423908 XM_421770.3 XP_421770.3
lizard (Anolis carolinensis)	Reptilia	AFAP1L2⁶	--	67(a)	1 ↔ 1	GL344115.1(1112-62995)
African clawed frog (Xenopus laevis)	Amphibia	BC057722.1²	--	80.17(n)		BC057722.1
zebrafish (Danio rerio)	Actinopterygii	LOC567369¹	actin filament-associated protein 1-like 2-like	59.66(n) 55.44(a)		567369 XM_690662.4 XP_695754.3

ENSEMBL Gene Tree for AFAP1L2 (if available)
TreeFam Gene Tree for AFAP1L2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for AFAP1L2 gene

AFAP1² AFAP1L1²

1 SIMAP similar gene for AFAP1L2 using alignment to 3 protein entries: AF1L2_HUMAN (see all proteins):

AFAP1

AFAP1L2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs59256194^1,2	C,F,	--	109692406(+)	`TGAAGG/TAGGGG`	1	--	int¹		1		WA	118
rs192467391^1,2		--	116054264(+)	`TACTAA/CTTAGG`	2	--	int¹		0	--	--	--	--
rs76745349^1,2	F,	--	116054304(+)	`TTTCCC/AAAGAA`	2	--	int¹		1		WA	118
rs141787331^1,2		--	116054419(+)	`CTGTAC/GAACTA`	2	--	int¹		0	--	--	--	--
rs185020028^1,2		--	116054470(+)	`AGGCTA/GAGTTT`	2	--	int¹		0	--	--	--	--
rs150577415^1,2		--	116054540(+)	`AGAACC/GCCCCA`	2	--	int¹		0	--	--	--	--
rs138603987^1,2		--	116054567(+)	`ATTTCA/CTGAAC`	2	--	int¹		0	--	--	--	--
rs7350409^1,2	C,F,A,H,	--	116054585(+)	`AACTTC/GAAATA`	2	--	ut3¹		12		NA NS EA WA	922
rs10536165^1,2	C,	--	116054616(+)	`AAAAC-/CTAA CTAAC`	2	--	ut3¹		0	--	--	--	--
rs55838102^1,2	C	--	116054618(+)	`TAACT-/AACT CACCA`	2	--	ut3¹		1		NA	2

HapMap Linkage Disequilibrium report for AFAP1L2 (116054583 - 116164515 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AFAP1L2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AFAP1L2

DNA2.0 Custom Variant and Variant Library Synthesis for AFAP1L2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

AFAP1L2 for disorders           About GeneDecksing

OMIM gene information: 612420    OMIM disorders: --

4 diseases for AFAP1L2:    About MalaCards

alzheimer's disease thyroid cancer colorectal cancer thyroiditis

Human Genome Epidemiology (HuGE) Navigator: AFAP1L2 (2 documents)

Export disorders for AFAP1L2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for AFAP1L2 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with AFAP1L2)

Utopia: connect your pdf to the dynamic
world of online information

XB130, a novel adaptor protein for signal transduction. (PubMed id 17412687)^{1, 2, 3} Xu J....Liu M. (2007)
Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)^{1, 2, 3} Nagase T....Ohara O. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{1, 2} Deloukas P.... Rogers J. (2004)
Silencing of XB130 is associated with both the prognos is and chemosensitivity of gastric cancer. (PubMed id 22927913)¹ Shi M....Liao W. (2012)
XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt. (PubMed id 22928011)¹ Shiozaki A....Liu M. (2012)
Multivariate analysis of several molecular markers and clinicopathological features in postoperative prognosis of hepatocellular carci noma. (PubMed id 22190283)¹ Zuo Q....Liao W. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
XB130, a novel adaptor protein, promotes thyroid tumo r growth. (PubMed id 21224076)¹ Shiozaki A....Liu M. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84632	HGNC: 25901	AceView: KIAA1914	Ensembl:ENSG00000169129	euGenes: HUgn84632
ECgene: AFAP1L2	H-InvDB: AFAP1L2

(According to HUGE)
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HUGE: KIAA1914

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for AFAP1L2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for AFAP1L2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for AFAP1L2 gene:
Search GeneIP for patents involving AFAP1L2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AFAP1L2

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AFAP1L2 Gene

actin filament associated protein 1-like 2

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AFAP1L2 Gene

actin filament associated protein 1-like 2

Aliasesfor AFAP1L2 gene

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