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Aliases for AFAP1-AS1 Gene

Subcategory (RNA class) for AFAP1-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for AFAP1-AS1 Gene

  • AFAP1 Antisense RNA 1 2 3 5
  • AFAP1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • AFAP1 Antisense RNA (Non-Protein Coding) 2
  • AFAP1-AS 3
  • AFAP1AS 3

External Ids for AFAP1-AS1 Gene

Previous HGNC Symbols for AFAP1-AS1 Gene

  • AFAP1-AS

Summaries for AFAP1-AS1 Gene

GeneCards Summary for AFAP1-AS1 Gene

AFAP1-AS1 (AFAP1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for AFAP1-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AFAP1-AS1 Gene

Genomics for AFAP1-AS1 Gene

Regulatory Elements for AFAP1-AS1 Gene

Enhancers for AFAP1-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H007758 0.9 Ensembl ENCODE 14.1 +5.7 5651 2.2 ZNF316 POLR2A MAFG NFE2 EMSY MAFK NFE2L2 TRIM28 AFAP1 AFAP1-AS1 GC04M007761 PIR46874
GH04H007802 1.5 Ensembl ENCODE dbSUPER 7.6 +57.3 57294 16.8 PKNOX1 FOXA2 ATF1 ARID4B SIN3A DMAP1 ZNF143 FOS ZHX2 REST AFAP1 AFAP1-AS1 ACOX3 PIR60658 GC04M007832
GH04H007778 1.2 Ensembl ENCODE dbSUPER 8 +28.0 28044 8.1 IRF2 L3MBTL2 ZBED1 JUN ETV1 JUNB GABPA JUND POLR2A EGR1 AFAP1 AFAP1-AS1 PIR60658 GC04M007832
GH04H007765 0.7 ENCODE 10.7 +12.2 12236 1.8 SOX5 CEBPB CEBPG RARA CEBPA TCF7 NR2F6 KDM1A SMAD4 BCL6 AFAP1-AS1 PIR60658 GC04M007832
GH04H007770 0.8 ENCODE 8.1 +18.5 18536 3.4 CTCF PKNOX1 TBL1XR1 BATF ZIC2 POLR2A EED RUNX3 CREM NR2F1 AFAP1 AFAP1-AS1 PIR60658 GC04M007832
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AFAP1-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for AFAP1-AS1 Gene

Genomic Locations for AFAP1-AS1 Gene
24,839 bases
Plus strand

Genomic View for AFAP1-AS1 Gene

Genes around AFAP1-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AFAP1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AFAP1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFAP1-AS1 Gene

Proteins for AFAP1-AS1 Gene

Post-translational modifications for AFAP1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFAP1-AS1 Gene

Domains & Families for AFAP1-AS1 Gene

Gene Families for AFAP1-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AFAP1-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AFAP1-AS1 Gene

Function for AFAP1-AS1 Gene

Phenotypes From GWAS Catalog for AFAP1-AS1 Gene

Phenotypes for AFAP1-AS1 Gene

GenomeRNAi human phenotypes for AFAP1-AS1:
genes like me logo Genes that share phenotypes with AFAP1-AS1: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AFAP1-AS1 Gene

Localization for AFAP1-AS1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for AFAP1-AS1 gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AFAP1-AS1 Gene

Pathways & Interactions for AFAP1-AS1 Gene

SuperPathways for AFAP1-AS1 Gene

No Data Available

Interacting Proteins for AFAP1-AS1 Gene

Gene Ontology (GO) - Biological Process for AFAP1-AS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for AFAP1-AS1 Gene

Drugs & Compounds for AFAP1-AS1 Gene

No Compound Related Data Available

Transcripts for AFAP1-AS1 Gene

mRNA/cDNA for AFAP1-AS1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AFAP1-AS1 Gene

AFAP1 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for AFAP1-AS1 Gene

No ASD Table

Relevant External Links for AFAP1-AS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AFAP1-AS1 Gene

SOURCE GeneReport for Unigene cluster for AFAP1-AS1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AFAP1-AS1 Gene

Orthologs for AFAP1-AS1 Gene

Evolution for AFAP1-AS1 Gene

Gene Tree for AFAP1-AS1 (if available)
Gene Tree for AFAP1-AS1 (if available)

No data available for Orthologs for AFAP1-AS1 Gene

Paralogs for AFAP1-AS1 Gene

No data available for Paralogs for AFAP1-AS1 Gene

Variants for AFAP1-AS1 Gene

Sequence variations from dbSNP and Humsavar for AFAP1-AS1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000041405 -- 7,773,609(+) CTCTT(G/T)TTCAA intron-variant, nc-transcript-variant
rs1000059153 -- 7,770,203(+) CCCCC(A/G)AAGGA intron-variant
rs1000136565 -- 7,766,981(+) CCTTG(C/G)TCCCC intron-variant
rs1000155005 -- 7,755,525(+) GCAGC(A/G)CCCTG intron-variant
rs1000345550 -- 7,756,479(+) CACCA(G/T)CGACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AFAP1-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv822468 CNV gain 20364138
nsv1139213 CNV deletion 24896259
nsv1130812 CNV deletion 24896259
nsv1126034 CNV deletion 24896259
nsv1121623 CNV deletion 24896259
nsv1117961 CNV deletion 24896259
esv34196 OTHER inversion 12058347
esv2727079 CNV deletion 23290073
esv2727078 CNV deletion 23290073
esv2727077 CNV deletion 23290073
esv2727076 CNV deletion 23290073
esv2727075 CNV deletion 23290073
esv2727074 CNV deletion 23290073

Relevant External Links for AFAP1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AFAP1-AS1 Gene

Disorders for AFAP1-AS1 Gene

Relevant External Links for AFAP1-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for AFAP1-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AFAP1-AS1 Gene

Publications for AFAP1-AS1 Gene

  1. Long noncoding RNA AFAP1-AS1 indicates a poor prognosis of hepatocellular carcinoma and promotes cell proliferation and invasion via upregulation of the RhoA/Rac2 signaling. (PMID: 26892468) Zhang JY … Xu JM (International journal of oncology 2016) 2 3 60
  2. Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma. (PMID: 23333711) Wu W … Meltzer SJ (Gastroenterology 2013) 2 3 60
  3. Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in Cholangiocarcinoma. (PMID: 28535506) Lu X … Zhai W (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 60
  4. AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis. (PMID: 26245991) Zeng Z … Xiong W (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 60
  5. Critical role for the long non-coding RNA AFAP1-AS1 in the proliferation and metastasis of hepatocellular carcinoma. (PMID: 26803513) Lu X … Zhang S (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 60

Products for AFAP1-AS1 Gene

Sources for AFAP1-AS1 Gene

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