AES Gene
protein-coding GIFtS: 59
GCID: GC19M003003
|
|
amino-terminal enhancer of split
| |
Aliases
for AES gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Amino-Terminal Enhancer Of Split1 2 | | AES-22 | | GRG51 2 | | ESP12 | | TLE51 2 | | Amino Enhancer Of Split3 | | Gp130-Associated Protein GAM2 3 | | Protein ESP13 | | GRG2 3 | | Protein GRG3 | | AES-12 | | |
Export aliases for AES gene to outside databasesPrevious GC identifers: GC19M003145 GC19M002992 GC19M002819 |
Summaries
for AES gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AES:
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho,a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLEfamily of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantlyrepress the expression of other family member genes. Three transcript variants encoding different isoforms have beenfound for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: AES_HUMAN, Q08117Function: Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. Maybe required for the initiation and maintenance of the differentiated state
|
Genomic Views
for AES gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AES gene promoter:
STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for AES
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AES |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3AES Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M003003: view genomic region
(about GC identifiers)
Start:
|
3,052,908 bp from pter |
End:
|
3,063,105 bp from pter |
Size:
|
10,198 bases |
Orientation:
|
minus strand |
|
Proteins
for AES gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AES_HUMAN, Q08117 (See
protein sequence)Recommended Name: Amino-terminal enhancer of split Size: 197 amino acids; 21970 Da
Subunit: Homooligomer and heterooligomer with other family members. Binds TCF7 (By similarity). Binds the NF-kappa-Bsubunit RELA. Interacts with PHF12
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=AAC35517.1; Type=Erroneous initiation;
Secondary accessions: B2RBL0 Q12808 Q14CJ1 Q96TG9 Q9UDY9Alternative splicing: 2 isoforms: Q08117-1 Q08117-2 Explore the universe of human proteins at neXtProt for AES: NX_Q08117
Post-translational modifications:
Ubiquitinated by XIAP/BIRC41
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q08117
AES Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001121.2 NP_945320.1 NP_945321.1
ENSEMBL proteins: ENSP00000221561 ENSP00000466038 ENSP00000317537 ENSP00000467831 ENSP00000466179
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- |
AES for ontologies About GeneDecksing
AES Antibody Products:
Assay Products for AES: |
Protein
Domains /
Families
for AES gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AES for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q08117ProtoNet protein and cluster: Q08117 UniProtKB/Swiss-Prot: AES_HUMAN, Q08117Domain: Lacks the C-terminal WD repeatsSimilarity: Belongs to the WD repeat Groucho/TLE family |
Function
for AES gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: AES_HUMAN, Q08117Function: Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. Maybe required for the initiation and maintenance of the differentiated state Genatlas biochemistry entry for AES:amino-terminal enhancer of split,homologous to Drosophila ESG enhancer of split Groucho,mainly expressed inmuscle,heart,brain
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AES (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AES (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): AES (NM_001130) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AES | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AES |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AES |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
AES for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for AES:
Animal Models:
Mouse knock-out Aestm1Grid for AES
9 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Aes):
AES for phenotypes About GeneDecksing
|
Pathways & Interactions
for AES gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Androgen receptor signaling pathway | | | 2 | Regulation of Wnt-mediated beta catenin signaling and target gene transcription | | | 3 | Presenilin action in Notch and Wnt signaling | | | 4 | Wnt Signaling Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  R&D Systems Pathway for AES
3  BioSystems Pathways for AES
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AES
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/45 Interacting proteins for AES (Q081171, 2, 3 ENSP000002215614) via UniProtKB, MINT, STRING, and/or I2D (see all 45)About this table
Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IMP | 10660609 | | GO:0001501 | skeletal system development |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006357 | regulation of transcription from RNA polymerase II promoter |
-- | -- | | GO:0007275 | multicellular organismal development |
TAS | 8365415 |
AES for ontologies About GeneDecksing
|
Drugs & Compounds
for AES gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AES
Search CenterWatch for drugs/clinical trials and news about AES
|
Transcripts
for AES gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AES gene (3 alternative transcripts): NM_001130.5 NM_198969.1 NM_198970.1 Unigene Cluster for AES: Amino-terminal enhancer of split Hs.515053 [show with all ESTs]Unigene Representative Sequence: AK09515412 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592414 ENST00000221561(uc002lxb.1) ENST00000586742 ENST00000327141(uc002lwx.1 uc002lwy.1 uc002lwz.1)
ENST00000587393 ENST00000592330 ENST00000590067 ENST00000586839 ENST00000585557
ENST00000587083 ENST00000585782 ENST00000586003
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AES (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AES (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): AES (NM_001130) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AES | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AES |
Additional cDNA sequence: AF072902.1 AF269289.1 AK094591.1 AK095154.1 AK314713.1 BC113735.1 BC113737.1 U04241.1 X73357.1 X73358.1 24/42 DOTS entries (see all 42): DT.95176523 DT.100045190 DT.100858154 DT.91821772 DT.100808380 DT.121500399 DT.121500449 DT.87017800 DT.92460433 DT.100858157 DT.121500435 DT.100858140 DT.97863603 DT.100858142 DT.100858148 DT.121500452 DT.100858151 DT.91900598 DT.92375835 DT.95277120 DT.100045184 DT.100858139 DT.95277118 DT.97858075 24/995 AceView cDNA sequences (see all 995): AA149510 BM563578 BM983929 BM854347 BI907214 BM693746 AA719858 CR625320 BM791747 BU147483 AW071845 AI493621 CR598322 AI375532 BM668021 AL547805 AA700136 BM686583 BM824190 BQ961326 BQ933552 W05060 CR605502 BX279901
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for AES (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | | | - | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | - | | | | - | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | | | - | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | | | - | | | | | | - | | - | | | | - | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | - | | | | - | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for AES
|
Expression
for AES gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AES expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACGCAATGC
About this image
See AES Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AES
SOURCE GeneReport for Unigene cluster: Hs.515053
UniProtKB/Swiss-Prot: AES_HUMAN, Q08117Tissue specificity: Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in theheart, lung, kidney, brain and liver
SABiosciences Expression via Pathway-Focused PCR Arrays including AES:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AES
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AES | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AES | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AES | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AES |
Orthologs
for AES gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for AES gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Aes1 , 5 |
amino-terminal enhancer of split1, 5 |
86.35(n)1
99.47(a)1 |
|
10 (39.72 cM)5
147971 NM_010347.31 NP_034477.11
815595605 |
chicken
(Gallus gallus) |
Aves |
LOC1008585421 |
amino-terminal enhancer of split-like |
83.23(n)
97.42(a) |
|
100858542 XM_003642848.1 XP_003642896.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC684322 |
hypothetical protein MGC68432 |
76.34(n) |
|
BC060746.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC054644.12 |
-- |
79.53(n) |
|
393395 BC054644.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
unc-376 |
Transcription factor unc-37 |
9(a) |
1 ↔ 1 |
I(6742294-6745342) |
ENSEMBL Gene Tree for AES (if available)
TreeFam Gene Tree for AES (if available) |
Paralogs
for AES gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AES gene
- TLE32 TLE62 TLE22 TLE42 TLE12
4 SIMAP similar genes for AES using alignment to 4 protein entries: AES_HUMAN (see all proteins):TLE2 TLE4 TLE3 TLE1
AES for paralogs About GeneDecksing
|
Genomic Variants
for AES gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AES (3052908 - 3063105 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for AES
2 CNVs: 5071 5070 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AES |
|
Disorders
/ Diseases
for AES gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AES for disorders About GeneDecksing
OMIM gene information: 600188
OMIM disorders: --
6  diseases for AES: About MalaCardsautoimmune polyendocrine syndrome type 2 cystic fibrosis ataxia fibrosis
hepatitis neuronitis
2 diseases from the University of Copenhagen DISEASES database for AES:Autoimmune polyendocrine syndrome type 2 Cystic fibrosis Export disorders for AES gene to outside databases
|
Publications
for AES gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AES gene, integrated from 9 sources (see all 44):
(articles sorted by number of sources associating them with AES) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein. (PubMed id 8365415)1, 2, 3, 9 Miyasaka H.... Li S.S.-L. (1993)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. (PubMed id 11390640)1, 2 Yochum G.S. and Ayer D.E. (2001)
- Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho- related protein lacking WD40 repeats. (PubMed id 10660609)1, 2 Tetsuka T.... Okamoto T. (2000)
- Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta. (PubMed id 10748198)1, 2 Wang J.-C....Granner D.K. (2000)
- Genomic organization and chromosome localization to band 19p13.3 of the human AES gene: gene product exhibits strong similarity to the N- terminal domain of Drosophila enhancer of split Groucho protein. (PubMed id 9809752)1, 2 Hou E.W. and Li S.S.-L. (1998)
- The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1. (PubMed id 16002402)1, 9 Rave-Harel N....Mellon P.L. (2005)
- All Tcf HMG box transcription factors interact with Groucho-related co-repressors. (PubMed id 11266540)1, 9 Brantjes H.... Clevers H. (2001)
- Transducin-like enhancer of Split-1 (TLE1) combines wi th Forkhead box protein G1 (FoxG1) to promote neuronal survival. (PubMed id 22354967)1 Dastidar S.G....D'Mello S.R. (2012)
|
External Searches for AES gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AES gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AES gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AES gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for AES gene:
Search GeneIP for patents involving AES
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AES gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for AES | | OriGene shRNA RFP for AES | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AES | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AES | | | OriGene Protein Over-expression Lysate for AES | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AES | | OriGene 3'-UTR Clone for AES | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AES | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AES | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for AES | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AES | | OriGene Custom Protein Services for AES | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AES | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AES | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AES | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AES | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AES | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AES |
| |
 |  |  |  | |
| | | | Search Tocris compounds for AES |
| |  |  |  |  | | | | | | Recombinant Protein for AES |
|
 |
 |
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 | | | AES Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AES |
|  |  |  | | | | ThermoFisher Antibodies for AES |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AES |
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