Aliases for AEN Gene
External Ids for AEN Gene
Previous Symbols for AEN Gene
GeneCards Summary for AEN Gene
AEN (Apoptosis Enhancing Nuclease) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and exonuclease activity. An important paralog of this gene is ISG20.
UniProtKB/Swiss-Prot for AEN Gene
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.