Aliases for ADSSL1 Gene
External Ids for ADSSL1 Gene
Previous GeneCards Identifiers for ADSSL1 Gene
ADSSL1 is a muscle isozyme of adenylosuccinate synthase (EC 188.8.131.52), which catalyzes the initial reaction in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) (Sun et al., 2005 [PubMed 15786719]).[supplied by OMIM, Dec 2008]
GeneCards Summary for ADSSL1 Gene
ADSSL1 (Adenylosuccinate Synthase Like 1) is a Protein Coding gene. Among its related pathways are Metabolism and Pyrimidine metabolism (KEGG). GO annotations related to this gene include protein homodimerization activity and GTPase activity. An important paralog of this gene is ADSS.
UniProtKB/Swiss-Prot for ADSSL1 Gene
Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).