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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADRM1 Gene

protein-coding   GIFtS: 54
GCID: GC20P060877

Adhesion Regulating Molecule 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Adhesion Regulating Molecule 11 2     ARM12
Proteasome Regulatory Particle Non-ATPase 132 3     M(R) 110,000 Surface Antigen2
Rpn13 Homolog2 3     Proteasomal Ubiquitin Receptor ADRM12
110 KDa Cell Membrane Glycoprotein2 3     Gp1103
ARM-12 3     Adhesion-Regulating Molecule 13
GP1102 3     hRpn133

External Ids:    HGNC: 157591   Entrez Gene: 110472   Ensembl: ENSG000001307067   OMIM: 6106505   UniProtKB: Q161863   

Export aliases for ADRM1 gene to outside databases

Previous GC identifers: GC20P060641 GC20P061516 GC20P061563 GC20P060311 GC20P057653


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ADRM1 Gene:
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a
component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme,
ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased
cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has
been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. (provided by
RefSeq, Jul 2013)

GeneCards Summary for ADRM1 Gene: 
ADRM1 (adhesion regulating molecule 1) is a protein-coding gene. Diseases associated with ADRM1 include oligodendroglioma, and colorectal cancer. GO annotations related to this gene include endopeptidase activator activity and protease binding.

UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186
Function: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S
proteasome and promotes its activity

Gene Wiki entry for ADRM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011362.10  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ADRM1 gene promoter:
         Bach1   Pax-5   AML1a   MyoD   AREB6   Egr-2   HOXA5   ZID   MRF-2   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADRM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ADRM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADRM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

ADRM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADRM1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P060877:  view genomic region     (about GC identifiers)

Start:
60,877,149 bp from pter      End:
60,883,918 bp from pter
Size:
6,770 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186 (See protein sequence)
Recommended Name: Proteasomal ubiquitin receptor ADRM1  
Size: 407 amino acids; 42153 Da
Subunit: Interacts with PSMD1, ubiquitin and UCHL5
Subcellular location: Cytoplasm. Nucleus
Caution: Although initially described as a cell membrane glycoprotein, ADRM1 is intracellular and
non-glycosylated, and has probably no direct role in cell adhesion
3 PDB 3D structures from and Proteopedia for ADRM1:
2KQZ (3D)        2KR0 (3D)        2L5V (3D)    
Secondary accessions: A0PKB1 Q96FJ7 Q9H1P2

Explore the universe of human proteins at neXtProt for ADRM1: NX_Q16186

Explore proteomics data for ADRM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q16186

  • ADRM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ADRM1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001268366.1  NP_001268367.1  NP_008933.2  NP_783163.1  

    ENSEMBL proteins: 
     ENSP00000253003  

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    Cloud-Clone Corp. Proteins for ADRM1 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000502proteasome complex IDA16990800
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    ADRM1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR006773 26S_Psome_Ubiquitin-recp_Rpn13

    Graphical View of Domain Structure for InterPro Entry Q16186

    ProtoNet protein and cluster: Q16186

    1 Blocks protein domain: IPB006773 Adhesion regulating molecule

    UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186
    Domain: The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit
    of K48-linked diubiquitin allows UCHL5 access to the distal subunit (By similarity)
    Similarity: Belongs to the ADRM1 family
    Similarity: Contains 1 PH domain


    ADRM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADRM1_HUMAN, Q16186
    Function: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S
    proteasome and promotes its activity

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002020protease binding IPI18922472
    GO:0005515protein binding IPI16713569
    GO:0061133endopeptidase activator activity IDA16990800
    GO:0070628proteasome binding IDA18162577
         
    ADRM1 for ontologies           About GeneDecksing


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Adrm1):
     adipose tissue  behavior/neurological  cellular  endocrine/exocrine gland  growth/size 
     hematopoietic system  homeostasis/metabolism  immune system  mortality/aging  reproductive system 

    ADRM1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ADRM1 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADRM1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ADRM1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Protein Stability
    Protein Stability

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ADRM1
        Protein Stability



    ADRM1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADRM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/88 Interacting proteins for ADRM1 (Q161861, 2, 3 ENSP000002530034) via UniProtKB, MINT, STRING, and/or I2D (see all 88)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UCHL5Q9Y5K51, 2, 3, ENSP000003564254EBI-954387,EBI-1051183 MINT-3373742 MINT-4050637 MINT-4050597 MINT-4050618 MINT-3373565 MINT-4050661 MINT-3373718 MINT-4050722 MINT-3373835 MINT-3373811 I2D: score=5 STRING: ENSP00000356425
    UBCP0CG482, 3, ENSP000003448184MINT-7310443 MINT-7310399 MINT-7310429 MINT-7310499 MINT-7904643 MINT-7310471 MINT-7309220 MINT-7310415 MINT-7310485 MINT-7310457 I2D: score=2 STRING: ENSP00000344818
    UBQLN2Q9UHD92, 3, ENSP000003451954MINT-7308309 MINT-7308339 MINT-7308324 I2D: score=2 STRING: ENSP00000345195
    PSMD7P516652, 3, ENSP000002193134MINT-4050722 I2D: score=2 STRING: ENSP00000219313
    USMG5Q96IX52, 3, ENSP000003112454MINT-3373655 I2D: score=1 STRING: ENSP00000311245
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006368transcription elongation from RNA polymerase II promoter IMP11818576
    GO:0010950positive regulation of endopeptidase activity IDA16990800
    GO:0043248proteasome assembly IDA16990800

    ADRM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ADRM1

    Search CenterWatch for drugs/clinical trials and news about ADRM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ADRM1 gene (4 alternative transcripts): 
    NM_001281437.1  NM_001281438.1  NM_007002.3  NM_175573.2  

    Unigene Cluster for ADRM1:

    Adhesion regulating molecule 1
    Hs.90107  [show with all ESTs]
    Unigene Representative Sequence: CR749213
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491935 ENST00000253003(uc011aai.1 uc002ycn.3 uc002yco.3)
    ENST00000462554 ENST00000465805(uc002ycp.1)
    miRNA
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    Sirion Biotech Customized lentivirus for stable overexpression of ADRM1 
                         Customized lentivirus expression plasmids for stable overexpression of ADRM1 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADRM1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADRM1

    Additional mRNA sequence: 

    AK297567.1 AK307459.1 BC003059.2 BC010733.1 BC017245.2 BC093021.1 CR749213.1 D64154.1 

    24/28 DOTS entries (see all 28):

    DT.118190  DT.100877846  DT.100039151  DT.95072241  DT.120811648  DT.208025  DT.92325216  DT.100877859 
    DT.92452662  DT.100877844  DT.120811715  DT.120811786  DT.40214017  DT.92452663  DT.92452659  DT.100877860 
    DT.100877842  DT.100877850  DT.100877856  DT.100877866  DT.120811617  DT.208026  DT.92452654  DT.95072247 

    24/560 AceView cDNA sequences (see all 560):

    AI802285 AL698743 NM_007002 CR619277 CR620862 AI985734 CB130896 BM796362 
    CR608688 CR618998 CR616946 BM850798 CA448132 BU538322 BF724779 CB156202 
    T30250 BI833509 CR616656 NM_175573 CR624663 CR623968 CR591215 CA416385 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ADRM1 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13a · 13b · 13c ·
    SP1:                                -           -                                         -     -     -                                                         
    SP2:                                -           -                                         -     -     -                                                         
    SP3:                                -           -                                         -     -                                                               
    SP4:                                -           -     -     -     -                       -     -     -                                                         
    SP5:                                                                                -     -     -     -     -                                                   

    ExUns: 13d
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ADRM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ADRM1 expression in normal human tissues (normalized intensities)      ADRM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCTGGACT
    ADRM1 Expression
    About this image


    ADRM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/34 selected tissues (see all 34) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             testis ; cells in seminiferus ducts   

    See ADRM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ADRM1

    SOURCE GeneReport for Unigene cluster: Hs.90107
        SABiosciences Custom PCR Arrays for ADRM1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADRM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ADRM1 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Adrm11 , 5 adhesion regulating molecule 11, 5 87.31(n)1
    96.56(a)1
      2 (102.69 cM)5
    564361  NM_019822.31  NP_062796.21 
     1801714855 
    chicken
    (Gallus gallus)
    Aves ADRM11 adhesion regulating molecule 1 78.9(n)
    89.9(a)
      395365  NM_204651.1  NP_989982.1 
    lizard
    (Anolis carolinensis)
    Reptilia ADRM16
    adhesion regulating molecule 1
    85(a)
    1 ↔ 1
    4(150973317-150987012)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xoom2 oocyte membrane protein 75.22(n)    AB026995.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561072 similar to adhesion regulating molecule 1 80.84(n)   393988  BC045915.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG133491 , 3 CG133491 66(a)3
    56.89(n)1
    47.6(a)1
      365451  NM_001144192.11  NP_001137664.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C56G2.71 , 3 Protein C56G2.71 32(a)3
    46.47(n)1
    40.59(a)1
      III(6412146-6415052)3
    35658881  NM_065986.51  NP_498387.21 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RPN131 regulatory particle non-ATPase 13 47.34(n)
    43.84(a)
      817200  NM_128216.2  NP_565626.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g05948001 hypothetical protein 46.52(n)
    41.03(a)
      4339809  NM_001063044.1  NP_001056509.2 


    ENSEMBL Gene Tree for ADRM1 (if available)
    TreeFam Gene Tree for ADRM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ADRM1 gene
    1 SIMAP similar gene for ADRM1 using alignment to 1 protein entry:     ADRM1_HUMAN:
    DKFZp686G2045

    ADRM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/243 SNPs in ADRM1 are shown (see all 243)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1380118871,2
    --60876074(+) CCAAAG/TAGCTT 2 -- us2k10--------
    rs1417505311,2
    --60876189(+) GTTAAC/TACACA 2 -- us2k10--------
    rs767216061,2
    C,F--60876327(+) CCACCG/AAGACA 2 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1505857611,2
    --60876621(+) TCTTGC/TTTAAC 2 -- us2k10--------
    rs1127149651,2
    C--60876675(+) CTGACCTCT/-  
            
    CTATT
    2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1915000591,2
    --60876681(+) TCTCTA/GTTTTA 2 -- us2k10--------
    rs1836538541,2
    --60876704(+) TTATTA/TTTTTT 2 -- us2k10--------
    rs2000351971,2
    --60876704(+) TTATT-/ATTTTT 2 -- us2k10--------
    rs2009814101,2
    --60876706(+) TTATT-/ATTTTT 2 -- us2k10--------
    rs1128226121,2
    C,F--60876707(+) TTATTT/ATTTTT 2 -- us2k12Minor allele frequency- A:0.06CSA EA 121

    HapMap Linkage Disequilibrium report for ADRM1 (60877149 - 60883918 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for ADRM1 (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2422398CNV Duplication17116639
    nsv3441CNV Insertion18451855
    nsv913059CNV Loss21882294
    dgv4602n71CNV Loss21882294
    nsv913048CNV Loss21882294
    dgv4599n71CNV Loss21882294
    nsv913056CNV Loss21882294
    dgv4603n71CNV Loss21882294
    nsv470556CNV Loss18288195
    dgv4604n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610650    OMIM disorders: --

    4 diseases for ADRM1:    About MalaCards
    oligodendroglioma    colorectal cancer    ovarian cancer    endotheliitis


    ADRM1 for disorders           About GeneDecksing


    Export disorders for ADRM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ADRM1 gene, integrated from 9 sources (see all 64):
    (articles sorted by number of sources associating them with ADRM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of the complementary DNA of an M(r) 110,000 antigen expressed by human gastric carcinoma cells and upregulated by gamma-interferon. (PubMed id 8033103)1, 2, 3 Shimada S.... Greiner J.W. (1994)
    2. Proteasome subunit Rpn13 is a novel ubiquitin receptor. (PubMed id 18497817)1, 2 Husnjak K....Dikic I. (2008)
    3. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1, 2 Meierhofer D.... Kaiser P. (2008)
    4. hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. (PubMed id 17139257)1, 2 Qiu X.-B.... Goldberg A.L. (2006)
    5. A novel proteasome-interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes. (PubMed id 16990800)1, 2 Hamazaki J....Murata S. (2006)
    6. Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor. (PubMed id 16815440)1, 2 Joergensen J.P.... Hartmann-Petersen R. (2006)
    7. Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. (PubMed id 16906146)1, 2 Yao T.... Cohen R.E. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    10. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11047 HGNC: 15759 AceView: ADRM1 Ensembl:ENSG00000130706 euGenes: HUgn11047
    ECgene: ADRM1 H-InvDB: ADRM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ADRM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ADRM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ADRM1 gene:
    Search GeneIP for patents involving ADRM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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