Aliases for ADRM1 Gene
External Ids for ADRM1 Gene
Previous GeneCards Identifiers for ADRM1 Gene
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for ADRM1 Gene
ADRM1 (Adhesion Regulating Molecule 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Deubiquitination. GO annotations related to this gene include protease binding and endopeptidase activator activity.
UniProtKB/Swiss-Prot for ADRM1 Gene
Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.