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ADRM1 Gene

protein-coding   GIFtS: 55
GCID: GC20P060877

Adhesion Regulating Molecule 1

  Search for ADRM1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Adhesion Regulating Molecule 11 2     ARM12
Proteasome Regulatory Particle Non-ATPase 132 3     M(R) 110,000 Surface Antigen2
Rpn13 Homolog2 3     Proteasomal Ubiquitin Receptor ADRM12
110 KDa Cell Membrane Glycoprotein2 3     Gp1103
ARM-12 3     Adhesion-Regulating Molecule 13
GP1102 3     hRpn133

External Ids:    HGNC: 157591   Entrez Gene: 110472   Ensembl: ENSG000001307067   OMIM: 6106505   UniProtKB: Q161863   

Export aliases for ADRM1 gene to outside databases

Previous GC identifers: GC20P060641 GC20P061516 GC20P061563 GC20P060311 GC20P057653


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ADRM1 Gene:
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a
component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme,
ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased
cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has
been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. (provided by
RefSeq, Jul 2013)

GeneCards Summary for ADRM1 Gene:
ADRM1 (adhesion regulating molecule 1) is a protein-coding gene. GO annotations related to this gene include endopeptidase activator activity and protease binding.

UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186
Function: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S
proteasome and promotes its activity

Gene Wiki entry for ADRM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ADRM1 gene promoter:
         Bach1   Pax-5   AML1a   MyoD   AREB6   Egr-2   HOXA5   ZID   MRF-2   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADRM1 promoter sequence
   Search Chromatin IP Primers for ADRM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADRM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

ADRM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADRM1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P060877:  view genomic region     (about GC identifiers)

Start:
60,877,149 bp from pter      End:
60,883,918 bp from pter
Size:
6,770 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186 (See protein sequence)
Recommended Name: Proteasomal ubiquitin receptor ADRM1  
Size: 407 amino acids; 42153 Da
Subunit: Interacts with PSMD1, ubiquitin and UCHL5
Caution: Although initially described as a cell membrane glycoprotein, ADRM1 is intracellular and
non-glycosylated, and has probably no direct role in cell adhesion
3 PDB 3D structures from and Proteopedia for ADRM1:
2KQZ (3D)        2KR0 (3D)        2L5V (3D)    
Secondary accessions: A0PKB1 Q96FJ7 Q9H1P2

Explore the universe of human proteins at neXtProt for ADRM1: NX_Q16186

Explore proteomics data for ADRM1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys21, Lys34, Lys62, Lys379
  • Modification sites at PhosphoSitePlus

  • See ADRM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001268366.1  NP_001268367.1  NP_008933.2  NP_783163.1  

    ENSEMBL proteins: 
     ENSP00000253003  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006773 26S_Psome_Ubiquitin-recp_Rpn13

    Graphical View of Domain Structure for InterPro Entry Q16186

    ProtoNet protein and cluster: Q16186

    1 Blocks protein domain: IPB006773 Adhesion regulating molecule

    UniProtKB/Swiss-Prot: ADRM1_HUMAN, Q16186
    Domain: The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit
    of K48-linked diubiquitin allows UCHL5 access to the distal subunit (By similarity)
    Similarity: Belongs to the ADRM1 family
    Similarity: Contains 1 PH domain


    Find genes that share domains with ADRM1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADRM1_HUMAN, Q16186
    Function: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S
    proteasome and promotes its activity

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002020protease binding IPI18922472
    GO:0005515protein binding IPI16713569
    GO:0061133endopeptidase activator activity IDA16990800
    GO:0070628proteasome binding IDA18162577
         
    Find genes that share ontologies with ADRM1           About GenesLikeMe


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Adrm1):
     adipose tissue  behavior/neurological  cellular  endocrine/exocrine gland  growth/size/body 
     hematopoietic system  homeostasis/metabolism  immune system  mortality/aging  reproductive system 

    Find genes that share phenotypes with ADRM1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADRM1
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    hsa-let-7b-5p (MIRT052025), hsa-mir-744-5p (MIRT037740), hsa-mir-125b-5p (MIRT045933), hsa-mir-484 (MIRT042363), hsa-mir-769-3p (MIRT039100), hsa-mir-93-3p (MIRT038868), hsa-mir-19b-3p (MIRT031130), hsa-mir-24-3p (MIRT030392), hsa-mir-92a-3p (MIRT049521)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ADRM1_HUMAN, Q16186: Cytoplasm. Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane4
    cytosol3
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000502proteasome complex IDA16990800
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    Find genes that share ontologies with ADRM1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ADRM1 About    
    See pathways by source

    SuperPathContained pathways About
    1Protein Stability
    Protein Stability


    Find genes that share SuperPaths with ADRM1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ADRM1
        Protein Stability



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ADRM1
    Interactions:

        GeneGlobe Interaction Network for ADRM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ADRM1 (Q161861, 2, 3 ENSP000002530034) via UniProtKB, MINT, STRING, and/or I2D (see all 149)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UCHL5Q9Y5K51, 2, 3, ENSP000003564254EBI-954387,EBI-1051183 MINT-3373742 MINT-4050637 MINT-4050597 MINT-4050618 MINT-3373565 MINT-4050661 MINT-3373718 MINT-4050722 MINT-3373835 MINT-3373811 I2D: score=5 STRING: ENSP00000356425
    UBCP0CG481, 2, 3, ENSP000003448184EBI-954387,EBI-3390054 MINT-7310443 MINT-7310399 MINT-7310429 MINT-7310499 MINT-7904643 MINT-7310471 MINT-7309220 MINT-7310415 MINT-7310485 MINT-7310457 I2D: score=2 STRING: ENSP00000344818
    UBQLN2Q9UHD91, 2, 3, ENSP000003451954EBI-954387,EBI-947187 MINT-7308309 MINT-7308339 MINT-7308324 I2D: score=2 STRING: ENSP00000345195
    PSMD7P516652, 3, ENSP000002193134MINT-4050722 I2D: score=2 STRING: ENSP00000219313
    USMG5Q96IX52, 3, ENSP000003112454MINT-3373655 I2D: score=1 STRING: ENSP00000311245
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006368transcription elongation from RNA polymerase II promoter IMP11818576
    GO:0010950positive regulation of endopeptidase activity IDA16990800
    GO:0043248proteasome assembly IDA16990800

    Find genes that share ontologies with ADRM1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ADRM1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ADRM1 gene (4 alternative transcripts): 
    NM_001281437.1  NM_001281438.1  NM_007002.3  NM_175573.2  

    Unigene Cluster for ADRM1:

    Adhesion regulating molecule 1
    Hs.90107  [show with all ESTs]
    Unigene Representative Sequence: CR749213
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491935 ENST00000253003(uc011aai.1 uc002ycn.3 uc002yco.3)
    ENST00000462554 ENST00000465805(uc002ycp.1)
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ADRM1
      QuantiTect SYBR Green Assays in human, mouse, rat ADRM1
      QuantiFast Probe-based Assays in human, mouse, rat ADRM1

    Additional mRNA sequence: 

    AK297567.1 AK307459.1 BC003059.2 BC010733.1 BC017245.2 BC093021.1 CR749213.1 D64154.1 

    Selected DOTS entries (see all 28):

    DT.118190  DT.100877846  DT.100039151  DT.95072241  DT.120811648  DT.208025  DT.92325216  DT.100877859 
    DT.92452662  DT.100877844  DT.120811715  DT.120811786  DT.40214017  DT.92452663  DT.92452659  DT.100877860 
    DT.100877842  DT.100877850  DT.100877856  DT.100877866  DT.120811617  DT.208026  DT.92452654  DT.95072247 

    Selected AceView cDNA sequences (see all 560):

    CR620862 CR608688 CR619277 CR591215 BM796362 CA417570 CR593414 NM_007002 
    CR600340 BF811453 BM670879 AI423077 CR604310 BE897640 BE857121 CR626787 
    CR616656 AI802285 CR624663 BE907077 BM971339 CR616946 AI018379 BM672170 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ADRM1 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13a · 13b · 13c ·
    SP1:                                -           -                                         -     -     -                                                         
    SP2:                                -           -                                         -     -     -                                                         
    SP3:                                -           -                                         -     -                                                               
    SP4:                                -           -     -     -     -                       -     -     -                                                         
    SP5:                                                                                -     -     -     -     -                                                   

    ExUns: 13d
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ADRM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ADRM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCTGGACT
    ADRM1 Expression
    About this image


    ADRM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    ADRM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ADRM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.90107
        Custom PCR Arrays for ADRM1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ADRM1 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Adrm11 , 5 adhesion regulating molecule 11, 5 87.31(n)1
    96.56(a)1
      2 (102.69 cM)5
    564361  NM_019822.31  NP_062796.21 
     1801714855 
    chicken
    (Gallus gallus)
    Aves ADRM11 adhesion regulating molecule 1 78.9(n)
    89.9(a)
      395365  NM_204651.1  NP_989982.1 
    lizard
    (Anolis carolinensis)
    Reptilia ADRM16
    adhesion regulating molecule 1
    85(a)
    1 ↔ 1
    4(150973317-150987012)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xoom2 oocyte membrane protein 75.22(n)    AB026995.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561072 similar to adhesion regulating molecule 1 80.84(n)   393988  BC045915.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG133493   -- 66(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea C56G2.73   -- 32(a)   III(6412146-6415052)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RPN131 RPN13 47.86(n)
    43.96(a)
      817200  NM_001036348.1  NP_001031425.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g05948001 Os05g0594800 46.57(n)
    41.2(a)
      4339809  NM_001063044.1  NP_001056509.2 


    ENSEMBL Gene Tree for ADRM1 (if available)
    TreeFam Gene Tree for ADRM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ADRM1 gene
    1 SIMAP similar gene for ADRM1 using alignment to 1 protein entry:     ADRM1_HUMAN:
    DKFZp686G2045

    Find genes that share paralogs with ADRM1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ADRM1 (see all 243)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1380118871,2
    --60876074(+) CCAAAG/TAGCTT 2 -- us2k10--------
    rs1417505311,2
    --60876189(+) GTTAAC/TACACA 2 -- us2k10--------
    rs767216061,2
    C,F--60876327(+) CCACCG/AAGACA 2 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1505857611,2
    --60876621(+) TCTTGC/TTTAAC 2 -- us2k10--------
    rs1127149651,2
    C--60876675(+) CTGACCTCT/-  
            
    CTATT
    2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1915000591,2
    --60876681(+) TCTCTA/GTTTTA 2 -- us2k10--------
    rs1836538541,2
    --60876704(+) TTATTA/TTTTTT 2 -- us2k10--------
    rs2000351971,2
    --60876704(+) TTATT-/ATTTTT 2 -- us2k10--------
    rs2009814101,2
    --60876706(+) TTATT-/ATTTTT 2 -- us2k10--------
    rs1128226121,2
    C,F--60876707(+) TTATTT/ATTTTT 2 -- us2k12Minor allele frequency- A:0.06CSA EA 121

    HapMap Linkage Disequilibrium report for ADRM1 (60877149 - 60883918 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ADRM1 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422398CNV Duplication17116639
    nsv3441CNV Insertion18451855
    nsv913059CNV Loss21882294
    dgv4602n71CNV Loss21882294
    nsv913048CNV Loss21882294
    dgv4599n71CNV Loss21882294
    nsv913056CNV Loss21882294
    dgv4603n71CNV Loss21882294
    nsv470556CNV Loss18288195
    dgv4604n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ADRM1
    DNA2.0 Custom Variant and Variant Library Synthesis for ADRM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610650    OMIM disorders: --


    Find genes that share disorders with ADRM1           About GenesLikeMe


    Export disorders for ADRM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ADRM1 gene, integrated from 10 sources (see all 67):
    (articles sorted by number of sources associating them with ADRM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of the complementary DNA of an M(r) 110,000 antigen expressed by human gastric carcinoma cells and upregulated by gamma-interferon. (PubMed id 8033103)1, 2, 3 Shimada S.... Greiner J.W. (Cancer Res. 1994)
    2. Proteasome subunit Rpn13 is a novel ubiquitin receptor. (PubMed id 18497817)1, 2 Husnjak K.... Dikic I. (Nature 2008)
    3. hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. (PubMed id 17139257)1, 2 Qiu X.-B.... Goldberg A.L. (EMBO J. 2006)
    4. A novel proteasome-interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes. (PubMed id 16990800)1, 2 Hamazaki J....Murata S. (EMBO J. 2006)
    5. Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor. (PubMed id 16815440)1, 2 Joergensen J.P.... Hartmann-Petersen R. (J. Mol. Biol. 2006)
    6. Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. (PubMed id 16906146)1, 2 Yao T.... Cohen R.E. (Nat. Cell Biol. 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    9. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    10. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. (PubMed id 23503661)1 Sarraf S.A....Harper J.W. (Nature 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11047 HGNC: 15759 AceView: ADRM1 Ensembl:ENSG00000130706 euGenes: HUgn11047
    ECgene: ADRM1 H-InvDB: ADRM1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ADRM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ADRM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ADRM1 gene:
    Search GeneIP for patents involving ADRM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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