Aliases for ADRBK2 Gene
External Ids for ADRBK2 Gene
Previous GeneCards Identifiers for ADRBK2 Gene
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADRBK2 Gene
ADRBK2 (Adrenergic, Beta, Receptor Kinase 2) is a Protein Coding gene. Diseases associated with ADRBK2 include whim syndrome and cocaine abuse. Among its related pathways are Signaling by GPCR and Corticotropin-releasing hormone. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is GRK7.
UniProtKB/Swiss-Prot for ADRBK2 Gene
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.