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ADRBK2 Gene

protein-coding   GIFtS: 65

GC22P024285
adrenergic, beta, receptor kinase 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
BARK2 1, 2, 3, 5
Beta-ARK-2 3
EC 2.7.11.15 3
GRK3 1, 2, 3, 5
Descriptions
G-protein-coupled receptor kinase 3 3
adrenergic, beta, receptor kinase 2 2
beta-adrenergic receptor kinase 2 2
External Ids
HGNC: 2901
Entrez Gene: 1572
UniProtKB: P356263
Ensembl: ENSG000001000777
Search outside databases for aliases for ADRBK2 gene

Previous GC identifers: GC22P022657 GC22P024169

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ADRBK2:
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the
beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor
kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein
kinase catalytic domain having 95% similarity. These data suggest the existence of a family of
receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq]

UniProtKB/Swiss-Prot: ARBK2_HUMAN, P35626
Function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely
related receptors

Gene Wiki entry for ADRBK2 (Beta_adrenergic_receptor_kinase-2)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADRBK2 gene  

Entrez Gene cytogenetic band: 22q11|22q12.1   Ensembl cytogenetic band:  22q11.23   HGNC cytogenetic band: 22q11

ADRBK2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P024285:     (about GC identifiers)

Start:
24,290,861 bp from pter
End:
24,455,259 bp from pter
Size:
164,399 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000022.9  NT_011520.11  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ARBK2_HUMAN, P35626 (See protein sequence)
Recommended Name: Beta-adrenergic receptor kinase 2  
Size: 688 amino acids; 79710 Da
Secondary accessions: Q9UGW9

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_005151.2  

    ENSEMBL proteins: 
    ENSP00000317578 


    Human Recombinant Proteins 
    Invitrogen human recombinant proteins for ADRBK2
    Millipore Purified and/or Recombinant ADRBK2 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (GRK3, GRK2 + 3)
    Human Recombinant Proteins from Abnova (ADRBK2)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IDA18029348
    GO:0005886 plasma membrane IDA18029348
    About this table

    Antibodies for ADRBK2: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of ADRBK2
    Sigma-Aldrich Antibodies for ADRBK2
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (GRK3, GRK2 + 3), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ADRBK2)
    Search Novus for antibodies for ADRBK2

    Assays for ADRBK2: 
    Invitrogen Assays for ADRBK2
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/11 InterPro domains/families (see all 11 ):
     IPR015743 B-adrenergic_rcpt_kinase
     IPR017441 Protein_kinase_ATP_BS
     IPR000239 GPCR_kinase
     IPR002290 Ser_thr_pkinase
     IPR017442 Se/Thr_pkinase-rel


       GeneDecks  ADRBK2 for the domains selected above  
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    Graphical View of Domain Structure for InterPro Entry P35626

    ProtoNet protein and cluster: P35626

    4 Blocks protein families:
    IPB000239 GPCR kinase signature
    IPB000342 Regulator of G-protein signalling (RGS) protein signature
    IPB000961 Protein kinase C-terminal domain
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: ARBK2_HUMAN, P35626
    Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK
    subfamily
    Similarity: Contains 1 AGC-kinase C-terminal domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 protein kinase domain
    Similarity: Contains 1 RGS domain

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADRBK2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADRBK2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005160

                  Applied Biosystems Silencer® siRNAs for ADRBK2

                  Sigma-Aldrich siRNA and siRNA Panels for ADRBK2  
                         Sigma-Aldrich shRNA Panels and shRNA for ADRBK2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ADRBK2
    Millipore Clones for the Expression of ADRBK2
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005160
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005160
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_005160 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_005160

    UniProtKB/Swiss-Prot: ARBK2_HUMAN, P35626
    Function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely
    related receptors
    Catalytic activity: ATP + [beta-adrenergic receptor] = ADP + [beta-adrenergic receptor] phosphate
    Enzyme Number (IUBMB): EC 2.7.11.15 

    Genatlas biochemistry entry for ADRBK2:
    beta-adrenergic receptor kinase 2

    1 MGI mutant phenotype (inferred from 1 allele(MGI details for Adrbk2):

    taste/olfaction

    5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0004703 G-protein coupled receptor kinase activity IEA--
    GO:0004871 signal transducer activity IEA--
    GO:0005524 ATP binding IEA--
    GO:0016740 transferase activity IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for ADRBK2 (Maps provided by GeneGo):
     Angiotensin signaling via beta-arrestin

       GeneDecks  ADRBK2 for the pathways selected above  
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    1 Millipore Pathway for ADRBK2
     Development Angiotensin signaling via beta-Arrestin

       GeneDecks  ADRBK2 for the pathways selected above  
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    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  ADRBK2  (Your Favorite Gene powered by Ingenuity) 
     Cardiac &beta

       GeneDecks  ADRBK2 for the pathways selected above  
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    1 Kegg Pathway  (Kegg details for ADRBK2):
     hsa04740 Olfactory transduction

       GeneDecks  ADRBK2 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  ADRBK2 


    5/15 Interacting proteins for ADRBK2 (ENSP000003175783) via UniProtKB, MINT, and/or STRING (see all 15 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOENSP000002962713STRING (score=.959)
    SUCLG2ENSP000003074323STRING (score=.955)
    SAGENSP000002528573STRING (score=.951)
    ADRB2ENSP000003053723STRING (score=.941)
    GNAQENSP000002865483STRING (score=.925)
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468 protein amino acid phosphorylation IEA--
    GO:0007165 signal transduction TAS8427589
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ADRBK2
    6 Novoseek chemical compound relationships for ADRBK2 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    damgo 49.73 5 12750434 (3), 11299306 (1), 10092593 (1)
    pip2 44.09 3 8798768 (2)
    ionomycin 22.93 1 17179467 (1)
    oligonucleotide 0.00 1 11247813 (1)
    lipid 0.00 1 7673171 (1)
    calcium 0.00 2 17179467 (1), 18388243 (1)
    About this table

    1 PharmGKB drug compound relationship for ADRBK2 gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    Beta adrenergic antagonistsFA  11900882 14499340
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADRBK2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADRBK2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005160

                  Sigma-Aldrich siRNA and siRNA Panels for ADRBK2  
                         Sigma-Aldrich shRNA Panels and shRNA for ADRBK2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_005160  

    REFSEQ mRNAs for ADRBK2 gene: 

    NM_005160.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_005160  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005160
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005160
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_005160 

    Additional cDNA sequence: 

    AK055687.1 AK058103.1 AK123767.1 AK124922.1 AK292234.1 AK310398.1 BC021221.2 BC029563.1 
    BC036797.1 BC063545.1 CR617875.1 X69117.1 

    12 DOTS entries:

    DT.314219  DT.120646222  DT.413854  DT.91871442  DT.120646260  DT.95269662  DT.100732870  DT.99992562 
    DT.100639923  DT.91673436  DT.91891950  DT.99945421 

    24/198 AceView cDNA sequences (see all 198 ):

    CK825274 AA287659 BM310555 AV720235 AA257973 BC063545 AA830671 BI518807 
    AA741445 CA844322 F07794 AK055687 BX390226 N38770 AA322997 BX104431 
    CA418731 BF056793 AA832344 AW630342 CA849005 BC036797 BG058574 AW236822 

    highest scoring ESTs for ADRBK2:

    AA047782 AA057617 AA250850 AA278408 AA279133 AA287659 AA287692 AA526240 AA579796 AA648393 

    Unigene Cluster for ADRBK2:

    Adrenergic, beta, receptor kinase 2
    Hs.657494  [show with all ESTs]
    Unigene Representative Sequence: NM_005160


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ADRBK2

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:                    -     -                 -                                         -                                                                     
    SP2:                                                                                                                                                            
    SP3:                                            -                                                                                                               
    SP4:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  

    About this scheme

    ECgene alternative splicing isoforms for ADRBK2

    1 Ensembl transcript including schematic representation:
    ENST00000324198  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADRBK2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADRBK2

    1 / 2 / 3

    11 probe-sets matching ADRBK2 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    91589_at2, 3 U95-E 1 1.00 1.00 0.93 1.56 AI681911 0.80 1.00 0.91 1

    51940_at2, 3 U95-C 1 1.00 1.00 0.81 0.82 AL046134 0.40 1.00 0.76 1

    31795_at2, 3 U95-A 1 1.00 1.00 0.95 0.79 AL022329 0.20 1.00 0.72 1
    52075_at2, 3 U95-B 1 1.00 1.00 0.91 1.32 AI651212 0.80 1.00 0.91 1

    724_at2, 3 U95-A 1 1.00 1.00 0.69 0.55 HG1604-HT1604 0.20 1.00 0.72 1

    228771_at2, 3 U133-B 1 1.00 1.00 -- -- AI651212 0.80 1.00 0.91 1

    204184_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_005160 0.60 1.00 0.82 1

    204183_s_at2, 3 U133-A 1 1.00 1.00 -- -- AI478542 0.80 1.00 0.91 1

    228771_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    204184_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    204183_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ADRBK2 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ACTGAAACTT

    SOURCE GeneReport for Unigene cluster: Hs.657494

    Expression variation in blood from EXPOLDB for ADRBK2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ADRBK2 gene from 5/10 species (see all 10 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ADRBK21   -- adrenergic, beta, receptor kinase 2 89.06(n)
    94.58(a)
    486327  XM_543453.2  XP_543453.2 
    cow
    (Bos taurus)
    ADRBK21   -- adrenergic, beta, receptor kinase 2 89.44(n)
    95.49(a)
    282136  NM_174500.2  NP_776925.1 
    rat
    (Rattus norvegicus)
    Adrbk21   -- adrenergic, beta, receptor kinase 2 83.77(n)
    91.13(a)
    25372  NM_012897.1  NP_037029.1 
    mouse
    (Mus musculus)
    Adrbk21, 5 5 (60.00 cM)5
    adrenergic receptor kinase, beta 21, 5 83.14(n)1
    91.42(a)1
    3201291  NM_177078.31  NP_796052.21 
     AA3965165  AI8519275  (see all 16)
    chicken
    (Gallus gallus)
    ADRBK21   -- adrenergic, beta, receptor kinase 2 82.9(n)
    93.83(a)
    416904  XM_415195.2  XP_415195.2 
    About this table        Species with no ortholog for ADRBK2

    ENSEMBL Gene Tree for ADRBK2
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADRBK2 gene
    GRK72  ADRBK12  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/701 NCBI SNPs in ADRBK2 are shown (see all 701 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 196)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 22 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs7680861,2
    A,C,F,H,O24450336(+) TATCTC/TGTACC 1 -- ut3111Minor allele frequency- T:0.02MN NA EU EA WA 1098
    --
    rs57611221,2
    A,C,F,H24289309(+) CCTTCG/AACTGC 1 -- ng514Minor allele frequency- A:0.12EU EA WA 418
    rs65196231,2
    A,C,F,H24448976(+) AGCCGC/TACCCA 1 -- ut317Minor allele frequency- T:0.03NA EU EA WA 554
    rs65196221,2
    A,C,F,H24448524(+) TCCAGG/ACTCCC 1 -- ut31 ese34Minor allele frequency- A:0.01EU EA WA 418
    rs22059711,2
    A,C,F,H24288952(+) TATACT/CGTGCT 1 -- ng514Minor allele frequency- C:0.20EU EA WA 418
    rs22728591,2
    C,F,H24429541(+) TCACCG/ATGGTA 1 M/V mis1 ese38Minor allele frequency- A:0.00EU EA WA 832
    rs38273761,2
    C,F,H24454125(+) ATTGAA/CATAAT 1 -- ut315Minor allele frequency- C:0.01EU EA WA 598
    rs169806121,2
    C,F,H24449104(+) CATCAT/CTGGAA 1 -- ut31 ese37Minor allele frequency- C:0.03NA EU EA WA 562
    rs37471271,2
    C,F,H24448500(+) TGATCT/CATTCG 1 -- ut31 ese38Minor allele frequency- C:0.02EA NA EU WA 2060
    rs1338391,2
    C,F,H24453488(+) AGAAAT/CGCAGG 1 -- ut315Minor allele frequency- C:0.01MN EU EA WA 600
    About this table

    HapMap Linkage Disequilibrium images for ADRBK2 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 109636

    5 Novoseek disease relationships for ADRBK2 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    bipolar disorder 50.39 14 17106420 (2), 18075471 (2), 18359007 (2), 16359584 (2) (see all 6)
    retinoblastoma 25.85 2 11166332 (1)
    mania 24.92 1 12808434 (1)
    schizophrenia 9.20 9 15006433 (4), 17106420 (1)
    shock 0.00 2 17179467 (2)
    About this table

    2 PharmGKB disease relationships for ADRBK2 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Heart Failure, CongestiveFA  14499340
    HypertensionFA  14499340
    About this table

    Human Gene Mutation Database: ADRBK2
    Human Genome Epidemiology Navigator: ADRBK2 (5 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/97 PubMed articles for ADRBK2 gene (see all 97 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 157 HGNC: 290 AceView: ADRBK2 Ensembl:ENSG00000100077 euGenes: HUgn157
    ECgene: ADRBK2 H-InvDB: ADRBK2
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADRBK2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADRBK2-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADRBK2 Antibodies for ADRBK2
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADRBK2 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Search Novus for antibodies for ADRBK2

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