Aliases for ADRBK2 Gene
External Ids for ADRBK2 Gene
Previous GeneCards Identifiers for ADRBK2 Gene
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADRBK2 Gene
ADRBK2 (Adrenergic, Beta, Receptor Kinase 2) is a Protein Coding gene. Diseases associated with ADRBK2 include whim syndrome and cocaine abuse. Among its related pathways are Chemokine Signaling and Endocytosis. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is GRK7.
UniProtKB/Swiss-Prot for ADRBK2 Gene
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.