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Aliases for ADRA2C Gene

Aliases for ADRA2C Gene

  • Adrenoceptor Alpha 2C 2 3 5
  • Alpha-2 Adrenergic Receptor Subtype C4 3 4
  • Adrenergic, Alpha-2C-, Receptor 2 3
  • Alpha-2C Adrenoreceptor 3 4
  • Alpha-2C Adrenoceptor 3 4
  • Alpha-2CAR 3 4
  • ADRA2RL2 3 4
  • ADRA2L2 3 4
  • Alpha-2C Adrenergic Receptor 3
  • Alpha2-AR-C4 3
  • ALPHA2CAR 3
  • ADRARL2 3

External Ids for ADRA2C Gene

Previous HGNC Symbols for ADRA2C Gene

  • ADRA2L2
  • ADRA2RL2

Previous GeneCards Identifiers for ADRA2C Gene

  • GC04U990002
  • GC04M9J0040
  • GC04P003798

Summaries for ADRA2C Gene

Entrez Gene Summary for ADRA2C Gene

  • Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

GeneCards Summary for ADRA2C Gene

ADRA2C (Adrenoceptor Alpha 2C) is a Protein Coding gene. Diseases associated with ADRA2C include Raynaud Disease and Orthostatic Intolerance. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein heterodimerization activity. An important paralog of this gene is ADRA2A.

UniProtKB/Swiss-Prot for ADRA2C Gene

  • Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

Tocris Summary for ADRA2C Gene

  • Adrenergic alpha2 receptors (alpha2-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, beta1, beta2 and beta3. Adrenergic alpha2 receptors are divided into three subtypes in humans: alpha2A, alpha2B and alpha2C.

Gene Wiki entry for ADRA2C Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADRA2C Gene

Genomics for ADRA2C Gene

Regulatory Elements for ADRA2C Gene

Enhancers for ADRA2C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F003745 0.9 ENCODE 16.1 -20.0 -19968 1.3 PKNOX1 GLI4 ZNF2 RAD21 ZEB1 GLIS2 ZNF366 SCRT2 ZNF416 ZNF391 ADRA2C ENSG00000250986 GC04M003763 PIR54762 GC04M003694
GH04F003792 1 ENCODE 12.6 +25.8 25781 0.1 MLX ZFP64 ARID4B SIN3A ZNF48 SLC30A9 ZNF143 NFYC MXD4 MIER2 NOP14-AS1 ENSG00000250986 ADRA2C STX18-AS1 GC04P003863
GH04F004327 1.2 Ensembl ENCODE 5.6 +561.6 561572 0.8 ATF1 CBX3 CREB3L1 ARID4B DMAP1 ZNF48 RAD21 RARA CHAMP1 ZNF143 LYAR TMEM128 ADRA2C NSG1 ENSG00000248516 PIR59167
GH04F003826 1.5 FANTOM5 Ensembl ENCODE 4.3 +61.6 61624 2.5 MLX ZFP64 ARID4B DMAP1 ZNF48 SLC30A9 SP5 ZHX2 MXD4 MIER2 ADRA2C LYAR GC04P003863
GH04F003924 0.9 FANTOM5 ENCODE 4.4 +161.8 161787 6.4 PKNOX1 FOXK2 NFE2 PRDM1 SPI1 ENSG00000271977 FAM86EP ENPP7P9 LRPAP1 ADRA2C LOC100420818 ALG1L7P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ADRA2C on UCSC Golden Path with GeneCards custom track

Promoters for ADRA2C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001857134 -248 1401 RING1 CTCF SAP130 ARID4B ZNF48 RAD21 ZEB1 HIC1 ZFHX2 POLR2A
ENSR00001857135 1152 201 CTCF SSRP1 NRF1 KLF9 KDM1A ZIC2 EZH2

Genomic Location for ADRA2C Gene

Chromosome:
4
Start:
3,766,348 bp from pter
End:
3,768,526 bp from pter
Size:
2,179 bases
Orientation:
Plus strand

Genomic View for ADRA2C Gene

Genes around ADRA2C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADRA2C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADRA2C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADRA2C Gene

Proteins for ADRA2C Gene

  • Protein details for ADRA2C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P18825-ADA2C_HUMAN
    Recommended name:
    Alpha-2C adrenergic receptor
    Protein Accession:
    P18825
    Secondary Accessions:
    • P35369
    • Q9HB49

    Protein attributes for ADRA2C Gene

    Size:
    462 amino acids
    Molecular mass:
    49522 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA35513.1; Type=Frameshift; Positions=270, 296, 300; Evidence={ECO:0000305}; Sequence=AAC78723.1; Type=Frameshift; Positions=270, 296, 300; Evidence={ECO:0000305};

neXtProt entry for ADRA2C Gene

Post-translational modifications for ADRA2C Gene

  • Glycosylation at Asn 19 and Asn 33
  • Modification sites at PhosphoSitePlus

Other Protein References for ADRA2C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ADRA2C Gene

Domains & Families for ADRA2C Gene

Gene Families for ADRA2C Gene

Suggested Antigen Peptide Sequences for ADRA2C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P18825

UniProtKB/Swiss-Prot:

ADA2C_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
Family:
  • Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
genes like me logo Genes that share domains with ADRA2C: view

Function for ADRA2C Gene

Molecular function for ADRA2C Gene

GENATLAS Biochemistry:
adrenergic,alpha-2C-,receptor,G protein coupled receptor superfamily,without action on ion channels
UniProtKB/Swiss-Prot Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

Gene Ontology (GO) - Molecular Function for ADRA2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004935 adrenergic receptor activity IEA --
GO:0004938 alpha2-adrenergic receptor activity IEA,IDA 17215105
GO:0005515 protein binding IPI 16531006
GO:0031694 alpha-2A adrenergic receptor binding IPI 16605244
genes like me logo Genes that share ontologies with ADRA2C: view
genes like me logo Genes that share phenotypes with ADRA2C: view

Animal Models for ADRA2C Gene

MGI Knock Outs for ADRA2C:

Animal Model Products

Inhibitory RNA Products

Clone Products

  • R&D Systems cDNA Clones for ADRA2C (alpha-2C Adrenergic R/ADRA2C)

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ADRA2C Gene

Localization for ADRA2C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADRA2C Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADRA2C gene
Compartment Confidence
plasma membrane 5
endosome 4
nucleus 1

Gene Ontology (GO) - Cellular Components for ADRA2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 16605244
GO:0005768 endosome TAS 10196213
GO:0005886 plasma membrane IEA,TAS --
GO:0005887 integral component of plasma membrane IDA 16605244
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with ADRA2C: view

Pathways & Interactions for ADRA2C Gene

genes like me logo Genes that share pathways with ADRA2C: view

Gene Ontology (GO) - Biological Process for ADRA2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006940 regulation of smooth muscle contraction IEA --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA,TAS 9371698
GO:0007267 cell-cell signaling TAS 9371698
GO:0007565 female pregnancy IEA --
genes like me logo Genes that share ontologies with ADRA2C: view

No data available for SIGNOR curated interactions for ADRA2C Gene

Drugs & Compounds for ADRA2C Gene

(142) Drugs for ADRA2C Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Yohimbine Approved, Vet_approved Pharma Antagonist, antagonist, Target 27
Clonidine Approved Pharma Partial agonist, Agonist, agonist, Target 226
Apomorphine Approved, Investigational Pharma Partial agonist, Agonist, agonist, Target 37
Brimonidine Approved Pharma Full agonist, Agonist, agonist, Target 0
Bromocriptine Approved, Investigational Pharma Antagonist, agonist, Target 31

(3) Additional Compounds for ADRA2C Gene - From: IUPHAR, Tocris, and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(plusmn)-adrenaline
Partial agonist, Agonist
Medetomidine hydrochloride
86347-15-1

(5) Tocris Compounds for ADRA2C Gene

Compound Action Cas Number
Atipamezole hydrochloride Selective alpha2 antagonist 104075-48-1
BRL 44408 maleate Selective alpha2A antagonist 681806-46-2
Imiloxan hydrochloride Highly selective alpha2B antagonist 81167-22-8
Medetomidine hydrochloride Potent, highly selective alpha2 agonist 86347-15-1
RS 79948 hydrochloride Potent, selective alpha2 antagonist 186002-54-0

(57) ApexBio Compounds for ADRA2C Gene

Compound Action Cas Number
Acebutolol HCl 34381-68-5
Adrenalone HCl 62-13-5
Alfuzosin HCl α1 adrenoceptor antagonist,functionally uro-selective 81403-68-1
Bambuterol 81732-65-2
Betaxolol βadrenergic receptor blocker 659-18-7
Betaxolol HCl 63659-19-8
Bisoprolol fumarate 104344-23-2
Carvedilol 72956-09-3
Cisatracurium Besylate Neuromuscular-blocking drug 96946-42-8
Clonidine HCl 4205-91-8
Detomidine HCl 90038-01-0
Dexmedetomidine 113775-47-6
Dexmedetomidine HCl 145108-58-3
DL-Adrenaline 329-65-7
Doxazosin Mesylate α1-adrenergic receptor antagonist 77883-43-3
Epinephrine Bitartrate 51-42-3
Epinephrine HCl 55-31-2
Formoterol Hemifumarate 43229-80-7
Guanabenz Acetate 23256-50-0
Indacaterol Maleate 753498-25-8
Isoprenaline HCl 51-30-9
Ivabradine HCl 148849-67-6
Labetalol HCl 32780-64-6
L-Adrenaline 51-43-4
Lurasidone HCl Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor 367514-88-3
Maprotiline HCl 10347-81-6
Medetomidine HCl 86347-15-1
Methyldopa 555-30-6
Metoprolol Tartrate β1-adrenergic blocking agent 392-17-7
Mirabegron (YM178) 223673-61-8
Moxonidine hydrochloride α2AR/I1R agonist 75536-04-8
Naftopidil α1-adrenergic receptor antagonist 57149-07-2
Naftopidil DiHCl 57149-08-3
Naphazoline HCl 550-99-2
Nebivolol 152520-56-4
Nedaplatin 95734-82-0
Oxymetazoline HCl Alpha-1/alpha-2 agonist 2315-02-8
Phenoxybenzamine HCl 63-92-3
Phentolamine Mesylate Alpha 1/2-blocking agent 65-28-1
Phenylephrine HCl 61-76-7
Prazosin HCl α1 and α2B-adrenoceptor antagonist 19237-84-4
Propranolol HCl 318-98-9
Ritodrine HCl β-2 adrenergic receptor agonist 23239-51-2
Salbutamol Sulfate β-2 adrenergic receptor agonist 51022-70-9
Salmeterol xinafoate β2-adrenergic receptor agonist 94749-08-3
Scopine 498-45-3
Setiptiline Serotonin receptor antagonist 57262-94-9
Silodosin α1-adrenoceptor antagonist 160970-54-7
Synephrine HCl 5985-28-4
Terazosin HCl 70024-40-7
Terbutaline Sulfate 23031-32-5
Tetrahydrozoline HCl 522-48-5
Timolol Maleate 26921-17-5
Tizanidine HCl 64461-82-1
Tolazoline HCl 59-97-2
Xylazine α2-adrenoceptor agonist 7361-61-7
Xylazine HCl α2 Adrenoceptor agonist 23076-35-9
genes like me logo Genes that share compounds with ADRA2C: view

Transcripts for ADRA2C Gene

mRNA/cDNA for ADRA2C Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ADRA2C Gene

Adrenoceptor alpha 2C:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • R&D Systems cDNA Clones for ADRA2C (alpha-2C Adrenergic R/ADRA2C)

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADRA2C Gene

No ASD Table

Relevant External Links for ADRA2C Gene

GeneLoc Exon Structure for
ADRA2C
ECgene alternative splicing isoforms for
ADRA2C

Expression for ADRA2C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ADRA2C Gene

mRNA differential expression in normal tissues according to GTEx for ADRA2C Gene

This gene is overexpressed in Artery - Aorta (x8.2), Cervix - Endocervix (x6.7), and Artery - Tibial (x4.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ADRA2C Gene



NURSA nuclear receptor signaling pathways regulating expression of ADRA2C Gene:

ADRA2C

SOURCE GeneReport for Unigene cluster for ADRA2C Gene:

Hs.123022
genes like me logo Genes that share expression patterns with ADRA2C: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ADRA2C Gene

Orthologs for ADRA2C Gene

This gene was present in the common ancestor of animals.

Orthologs for ADRA2C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ADRA2C 34 35
  • 98.62 (n)
dog
(Canis familiaris)
Mammalia ADRA2C 34 35
  • 89.71 (n)
rat
(Rattus norvegicus)
Mammalia Adra2c 34
  • 84.6 (n)
mouse
(Mus musculus)
Mammalia Adra2c 34 16 35
  • 84.3 (n)
oppossum
(Monodelphis domestica)
Mammalia ADRA2C 35
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves ADRA2C 34 35
  • 72.07 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 45 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia adra2c 34
  • 68.64 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.26396 34
zebrafish
(Danio rerio)
Actinopterygii adra2c 34 35
  • 64.38 (n)
-- 34
fruit fly
(Drosophila melanogaster)
Insecta CG18208 36 35
  • 49 (a)
DopR2 36
  • 44 (a)
5-HT7 36
  • 33 (a)
Oct-TyrR 35
  • 24 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea sca-1 36
  • 31 (a)
ser-1 36
  • 31 (a)
octr-1 35
  • 30 (a)
ManyToMany
ser-2 35
  • 30 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 28 (a)
OneToMany
Species where no ortholog for ADRA2C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ADRA2C Gene

ENSEMBL:
Gene Tree for ADRA2C (if available)
TreeFam:
Gene Tree for ADRA2C (if available)

Paralogs for ADRA2C Gene

(18) SIMAP similar genes for ADRA2C Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ADRA2C: view

Variants for ADRA2C Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for ADRA2C Gene

ADA2C_HUMAN-P18825
The Del322-325 variant has a significant loss of function. It is approximately 10 times more frequent in African-Americans compared with Caucasians (allele frequencies 0.381 versus 0.040).

Sequence variations from dbSNP and Humsavar for ADRA2C Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs61767072 drug-response 3,767,570(+) GGCAG(-/GGGGCGGGGCCG)GGGGC upstream-variant-2KB, cds-indel
rs111296535 -- 3,768,316(+) CCCTA(A/C)ATGGG utr-variant-3-prime
rs111370723 -- 3,767,245(+) CTGTC(C/G/T)TCCTG upstream-variant-2KB, reference, synonymous-codon
rs112351502 -- 3,766,269(+) GCTCG(A/C)CGCCG upstream-variant-2KB
rs112527024 -- 3,768,645(+) ACCCT(G/T)GGCCT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ADRA2C Gene

Variant ID Type Subtype PubMed ID
dgv854n67 CNV gain 20364138
dgv8928n54 CNV loss 21841781
dgv8929n54 CNV loss 21841781
esv26274 CNV loss 19812545
esv2759219 CNV gain 17122850
esv3575674 CNV gain 25503493
nsv1005210 CNV gain 25217958
nsv1074138 CNV deletion 25765185
nsv1133576 CNV deletion 24896259
nsv519631 CNV loss 19592680
nsv593468 CNV loss 21841781
nsv593469 CNV gain 21841781
nsv593470 CNV gain+loss 21841781
nsv949772 CNV deletion 24416366
nsv997647 CNV gain 25217958
nsv998670 CNV gain 25217958

Variation tolerance for ADRA2C Gene

Residual Variation Intolerance Score: 34.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.58; 86.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ADRA2C Gene

Human Gene Mutation Database (HGMD)
ADRA2C
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADRA2C

Disorders for ADRA2C Gene

MalaCards: The human disease database

(3) MalaCards diseases for ADRA2C Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
raynaud disease
  • raynaud's disease
orthostatic intolerance
  • neurocirculatory asthenia
attention deficit-hyperactivity disorder
  • attention deficit hyperactivity disorder
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ADRA2C

Genetic Association Database (GAD)
ADRA2C
Human Genome Epidemiology (HuGE) Navigator
ADRA2C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADRA2C
genes like me logo Genes that share disorders with ADRA2C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ADRA2C Gene

Publications for ADRA2C Gene

  1. Identification of an additional gene belonging to the alpha 2 adrenergic receptor family in the human genome by PCR. (PMID: 1849485) Chhajlani V. … Wikberg J.E.S. (FEBS Lett. 1991) 2 3 4 22 64
  2. An alpha2C-adrenergic receptor polymorphism alters the norepinephrine-lowering effects and therapeutic response of the beta-blocker bucindolol in chronic heart failure. (PMID: 19880803) Bristow M.R. … Liggett S.B. (Circ Heart Fail 2010) 3 22 46 64
  3. The alpha2C-adrenoceptor deletion322-325 variant and cold-induced vasoconstriction. (PMID: 19444546) Friedman E.A. … Kurnik D. (Clin. Auton. Res. 2009) 3 22 46 64
  4. Association between the alpha-2C-adrenergic receptor gene and attention deficit hyperactivity disorder in a Korean sample. (PMID: 18835330) Cho S.C. … Park T.W. (Neurosci. Lett. 2008) 3 22 46 64
  5. Multiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival. (PMID: 18947427) Kardia S.L. … Liggett S.B. (BMC Med. Genet. 2008) 3 22 46 64

Products for ADRA2C Gene

Sources for ADRA2C Gene

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