ADRA1D Gene
protein-coding GIFtS: 64
GCID: GC20M004149
|
|
adrenoceptor alpha 1D(Previous names: adrenergic, alpha-1D-, receptor )
| |
Aliases
for ADRA1D gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adrenoceptor Alpha 1D1 2 | | Alpha-Adrenergic Receptor 1a2 3 | | ADRA1A1 2 3 5 | | ALPHA12 | | ADRA11 2 | | DAR2 | | ADRA1R1 2 | | Adrenergic, Alpha -1D-, Receptor2 | | Adrenergic, Alpha-1D-, Receptor1 2 | | Adrenergic, Alpha-1A-, Receptor2 | | Alpha-1A Adrenergic Receptor2 3 | | Alpha-1D Adrenergic Receptor2 | | Alpha-1D Adrenoceptor2 3 | | Alpha-1D-Adrenergic Receptor2 | | Alpha-1D Adrenoreceptor2 3 | | DJ779E11.21 |
Export aliases for ADRA1D gene to outside databasesPrevious GC identifers: GC20M004189 GC20M004196 |
Summaries
for ADRA1D gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ADRA1D:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activatemitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A,-1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patternsof activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this genecomprises 2 exons and a single intron that interrupts the coding region. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ADA1D_HUMAN, P25100Function: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium
 summary
for ADRA1D: Adrenergic alpha1 receptors (alpha1-adrenoceptors) are members of the adrenergic receptor group of
G-protein-coupled receptors that also includes alpha2A, alpha2B, alpha2C, beta1, beta2 and beta3. The
adrenergic alpha1 receptors are further divided into three subtypes: alpha1A, alpha1B and alpha1D receptors.
lpha1-adrenoceptors are widely distributed in both the CNS and periphery where they play a major role in
smooth muscle contraction. A fourth alpha1 receptor subtype has been postulated and is designated as alpha1L
based on its low affinity for prazosin. It has been suggested that this subtype may represent a different
conformational state of the alpha1A subtype.
Gene Wiki entry for ADRA1D (Alpha-1D adrenergic receptor)
|
Genomic Views
for ADRA1D gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ADRA1D gene promoter:
SRF PPAR-gamma1 SRF (504 AA) Nkx2-5 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ADRA1D
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADRA1D |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13ADRA1D Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M004149: view genomic region
(about GC identifiers)
Start:
|
4,201,278 bp from pter |
End:
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4,229,721 bp from pter |
Size:
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28,444 bases |
Orientation:
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minus strand |
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Proteins
for ADRA1D gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ADA1D_HUMAN, P25100 (See
protein sequence)Recommended Name: Alpha-1D adrenergic receptor Size: 572 amino acids; 60463 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q9NPY0Explore the universe of human proteins at neXtProt for ADRA1D: NX_P25100
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P25100
ADRA1D Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000669.1
ENSEMBL proteins: ENSP00000368766 Reactome Protein details: P25100
Human Recombinant Protein Products for ADRA1D:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ADRA1D for ontologies About GeneDecksing
ADRA1D Antibody Products:
Assay Products for ADRA1D: |
Protein
Domains /
Families
for ADRA1D gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ADRA1D for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P25100ProtoNet protein and cluster: P25100 2 Blocks protein families: IPB000363 Alpha-1A adrenergic receptor signature IPB002233 Adrenergic receptor signature
UniProtKB/Swiss-Prot: ADA1D_HUMAN, P25100Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily |
Function
for ADRA1D gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ADA1D_HUMAN, P25100Function: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium Genatlas biochemistry entry for ADRA1D:adrenergic,alpha-1D-,receptor,G protein coupled receptor superfamily,stimulating,acting through thephosphadidylinositol/Ca2+ second messenger system
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004937 | alpha1-adrenergic receptor activity |
IEA | -- |
ADRA1D for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ADRA1D:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Adra1d):
ADRA1D for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Adra1dtm1Gzt for ADRA1D
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ADRA1D (NM_000678) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADRA1D | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ADRA1D |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADRA1D |
|
Pathways & Interactions
for ADRA1D gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Translation_Translation regulation by Alpha-1 adrenergic receptors | | | 2 | Class A/1 (Rhodopsin-like receptors) | | | 3 | Activation of cAMP-Dependent PKA | | | 4 | Signaling by GPCR | | | 5 | G alpha (q) signalling events | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for ADRA1D
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ADRA1D
2  GeneGo (Thomson Reuters) Pathways for ADRA1D
4  BioSystems Pathways for ADRA1D
5/10 
Reactome Pathways for ADRA1D (see all 10)
2  PharmGKB Pathways for ADRA1D
4 
Kegg Pathways (Kegg details for ADRA1D):
ADRA1D for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADRA1D
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/142 Interacting proteins for ADRA1D (P251003 ENSP000003687664) via UniProtKB, MINT, STRING, and/or I2D (see all 142)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001986 | negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure |
IEA | -- | | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure |
IEA | -- | | GO:0006259 | DNA metabolic process |
TAS | 10969806 | | GO:0007186 | G-protein coupled receptor signaling pathway |
TAS | 1656955 | | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway |
TAS | 10820200 |
ADRA1D for ontologies About GeneDecksing
|
Drugs & Compounds
for ADRA1D gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ADRA1D for compounds About GeneDecksing
Compounds for ADRA1D available from Tocris Bioscience About this table
1 HMDB Compound for ADRA1D About this table
10/24 DrugBank Compounds for ADRA1D (see all 24) About this table
4 Novoseek chemical compound relationships for ADRA1D gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| bmy7378 |
79.3 |
1 |
16426068 (1) |
| tamsulosin |
67.2 |
1 |
15639685 (1) |
| norepinephrine |
48.7 |
1 |
17404580 (1) |
| phenylephrine |
35.4 |
1 |
10344211 (1) |
Search CenterWatch for drugs/clinical trials and news about ADRA1D / ADA1D
|
Transcripts
for ADRA1D gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ADRA1D gene: NM_000678.3 Unigene Cluster for ADRA1D: Adrenoceptor alpha 1D Hs.557 [show with all ESTs]Unigene Representative Sequence: NM_0006781 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000379453(uc002wkr.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ADRA1D (NM_000678) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADRA1D | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ADRA1D |
Additional cDNA sequence: L31772.1 S70782.1 U03864.1 4 DOTS entries: DT.442233 DT.92416103 DT.95254294 DT.95357194 21 AceView cDNA sequences: BX280890 AI457674 NM_000678 AI611270 CA310090 BI828457 U03864 S70782 L31772 BE439970 CA424283 AA809802 M76446 AW975996 AW875208 AW875213 BM546478 AA921964 AA909273 AW577200 BQ067091
GeneLoc Exon Structure
|
Expression
for ADRA1D gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ADRA1D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCCCGCTGT
About this image
See ADRA1D Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ADRA1D
SOURCE GeneReport for Unigene cluster: Hs.557
SABiosciences Expression via Pathway-Focused PCR Arrays including ADRA1D:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADRA1D
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ADRA1D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADRA1D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADRA1D | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADRA1D |
Orthologs
for ADRA1D gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ADRA1D gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ADRA1D1 |
adrenergic, alpha-1D-, receptor |
68.35(n)
64.65(a) |
|
422933 XM_420871.2 XP_420871.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ADRA1D6 |
-- |
67(a) |
1 ↔ 1 |
GL343407.1(235534-236439) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5686141 |
alpha-1D adrenergic receptor-like |
62.71(n)
62.85(a) |
|
568614 XM_691951.2 XP_697043.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
ser-66ser-56 |
SERotonin/octopamine receptor family member (ser-6...SERotonin/octopamine receptor family member (ser-5... |
24(a)23(a) |
possible ortholog1 ↔ many |
IV(2960121-2964393) I(8384974-8386972) |
ENSEMBL Gene Tree for ADRA1D (if available)
TreeFam Gene Tree for ADRA1D (if available) |
Paralogs
for ADRA1D gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ADRA1D gene
- DRD42 HTR1A2 ADRA1B2 DRD22 HTR1F2 HTR72 ADRA2C2 ADRA2A2
- HTR1D2 ADRA2B2 ADRA1A2 HTR1E2 DRD32 HTR5A2 HTR1B2
17 SIMAP similar genes for ADRA1D using alignment to 2 protein entries: ADA1D_HUMAN (see all proteins):ADRA1A ADRA1B DRD3 HTR1B HTR1F HTR5A
HTR1D HTR1E ADRB3 DRD1 HTR7 5HT1A
DRD5 HTR1A HRH2 ADRB1 HTR6
ADRA1D for paralogs About GeneDecksing
|
Genomic Variants
for ADRA1D gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ADRA1D (4201278 - 4229721 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ADRA1D
1 Indel: 12147 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADRA1D |
|
Disorders
/ Diseases
for ADRA1D gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ADRA1D for disorders About GeneDecksing
OMIM gene information: 104219
OMIM disorders: --
15  diseases for ADRA1D: About MalaCardsalpha 1-antitrypsin deficiency essential hypertension impotence dilated cardiomyopathy
gastroparesis prostatic hypertrophy cystitis hypertension
cardiomyopathy prostatitis pharyngitis prostate cancer
hypoxia neuronitis interstitial cystitis
4 diseases from the University of Copenhagen DISEASES database for ADRA1D:Alpha 1-antitrypsin deficiency Prostatic hypertrophy Hypertension Impotence 3 Novoseek disease relationships for ADRA1D gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| benign prostatic hyperplasia |
43.8 |
1 |
17254786 (1) |
| essential hypertension |
32.3 |
3 |
16685204 (2) |
| obstruction |
0 |
1 |
15112040 (1) |
Genetic Association Database (GAD): ADRA1D
Human Genome Epidemiology (HuGE) Navigator: ADRA1D (8 documents)
Export disorders for ADRA1D gene to outside databases
|
Publications
for ADRA1D gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ADRA1D gene, integrated from 9 sources (see all 113):
(articles sorted by number of sources associating them with ADRA1D) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular analysis of adrenergic receptor genes and interleukin-4/interleukin-4 receptor genes in patients with interstitial cystitis. (PubMed id 12442007)1, 4, 9 Sugaya K....Ogawa Y. (2002)
- Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells. (PubMed id 7746284)1, 2, 9 Esbenshade T.A.... Murphy T.J. (1995)
- Amino acids of the human alpha1d-adrenergic receptor involved in antagonist binding. (PubMed id 18187928)1, 7, 9 Nagaoka Y....Nagatomo T. (2008)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. (PubMed id 7815325)1, 2 Schwinn D.A.... Bailey D.S. (1995)
- Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c. (PubMed id 8024574)1, 2 Weinberg D.H.... Bayne M. (1994)
- The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype. (PubMed id 8183249)1, 2 Forray C.... Gluchowski C. (1994)
- Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5. (PubMed id 8039425)1, 3 Loftus S.K....Wasmuth J.J. (1994)
- Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor. (PubMed id 1656955)1, 2 Bruno J.F.... Berelowitz M. (1991)
- Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction. (PubMed id 16533813)1, 9 Chen Z....Minneman K.P. (2006)
|
External Searches for ADRA1D gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ADRA1D gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ADRA1D gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ADRA1D gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ADRA1D | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ADRA1D gene:
Search GeneIP for patents involving ADRA1D
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ADRA1D gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for ADRA1D | | OriGene shRNA RFP for ADRA1D | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADRA1D | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADRA1D | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ADRA1D | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADRA1D | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ADRA1D | | OriGene Custom Protein Services for ADRA1D | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADRA1D | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADRA1D | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADRA1D | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADRA1D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADRA1D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADRA1D |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADRA1D |
|  |  |  |  | | | | ThermoFisher Antibodies for ADRA1D |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ADRA1D |
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