Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ADRA1B Gene

Aliases for ADRA1B Gene

  • Adrenoceptor Alpha 1B 2 3 5
  • Adrenergic, Alpha-1B-, Receptor 2 3
  • Alpha-1B Adrenoreceptor 3 4
  • Alpha-1B Adrenoceptor 3 4
  • Alpha-1B Adrenergic Receptor 3
  • ALPHA1BAR 3
  • ADRA1 3

External Ids for ADRA1B Gene

Previous GeneCards Identifiers for ADRA1B Gene

  • GC05P159198
  • GC05P159853
  • GC05P159324
  • GC05P159276
  • GC05P154438
  • GC05P159343

Summaries for ADRA1B Gene

Entrez Gene Summary for ADRA1B Gene

  • Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]

GeneCards Summary for ADRA1B Gene

ADRA1B (Adrenoceptor Alpha 1B) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and p75 NTR receptor-mediated signalling. GO annotations related to this gene include G-protein coupled receptor activity and alpha1-adrenergic receptor activity. An important paralog of this gene is ADRA1D.

UniProtKB/Swiss-Prot for ADRA1B Gene

  • This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.

Tocris Summary for ADRA1B Gene

  • Adrenergic alpha1 receptors (alpha1-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha2A, alpha2B, alpha2C, beta1, beta2 and beta3. The adrenergic alpha1 receptors are further divided into three subtypes: alpha1A, alpha1B and alpha1D receptors.

Gene Wiki entry for ADRA1B Gene

Additional gene information for ADRA1B Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADRA1B Gene

Genomics for ADRA1B Gene

Regulatory Elements for ADRA1B Gene

Enhancers for ADRA1B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H159772 1.4 Ensembl ENCODE dbSUPER 8.8 -91.6 -91629 1 ATF1 RB1 KLF17 SIN3A FEZF1 RAD21 ZEB1 EGR1 ZNF366 FOS ADRA1B GC05P159763 LOC105377689
GH05H159786 0.7 ENCODE dbSUPER 11.2 -77.5 -77503 1 POLR2A NR3C1 NR2F2 ADRA1B GC05P159763 LOC105377689
GH05H159825 1.2 Ensembl ENCODE dbSUPER 5.9 -38.8 -38802 2 JUN MAX EBF1 BATF ZIC2 EED SCRT2 RCOR1 FOS ZNF548 EBF1 LINC02202 ADRA1B LOC105377689 GC05P159763
GH05H159780 0.8 ENCODE dbSUPER 8.7 -85.1 -85124 1 JUND ZNF175 CEBPG FOS SP7 NR2F2 NR2C2 ADRA1B GC05P159763 LOC105377689
GH05H159819 0.8 Ensembl ENCODE 8.6 -45.2 -45164 1 JUND NR3C1 ZIC2 RAD21 NR2F2 ADRA1B LOC105377689 GC05P159763
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ADRA1B on UCSC Golden Path with GeneCards custom track

Genomic Location for ADRA1B Gene

Chromosome:
5
Start:
159,865,080 bp from pter
End:
159,986,178 bp from pter
Size:
121,099 bases
Orientation:
Plus strand

Genomic View for ADRA1B Gene

Genes around ADRA1B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADRA1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADRA1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADRA1B Gene

Proteins for ADRA1B Gene

  • Protein details for ADRA1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P35368-ADA1B_HUMAN
    Recommended name:
    Alpha-1B adrenergic receptor
    Protein Accession:
    P35368
    Secondary Accessions:
    • B0LPE1

    Protein attributes for ADRA1B Gene

    Size:
    520 amino acids
    Molecular mass:
    56836 Da
    Quaternary structure:
    • Homo- and heterooligomer. Heterooligomerizes with ADRA1B homooligomers in cardiac myocytes (PubMed:22120526). Interacts with CAVIN4 (PubMed:24567387).

neXtProt entry for ADRA1B Gene

Post-translational modifications for ADRA1B Gene

  • Glycosylation at Asn10, posLast=2424, Asn29, and Asn34
  • Modification sites at PhosphoSitePlus

Other Protein References for ADRA1B Gene

No data available for DME Specific Peptides for ADRA1B Gene

Domains & Families for ADRA1B Gene

Gene Families for ADRA1B Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Cancer-related genes
  • FDA approved drug targets
  • G-protein coupled receptors
  • Plasma proteins
  • Predicted membrane proteins

Suggested Antigen Peptide Sequences for ADRA1B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P35368

UniProtKB/Swiss-Prot:

ADA1B_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.
Family:
  • Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.
genes like me logo Genes that share domains with ADRA1B: view

Function for ADRA1B Gene

Molecular function for ADRA1B Gene

GENATLAS Biochemistry:
adrenergic,alpha-1B-,receptor,G protein coupled receptor superfamily,stimulating,acting through the phosphatidylinositol/Ca2+ second messenger system,involved in the control of vascular tone
UniProtKB/Swiss-Prot Function:
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.

Gene Ontology (GO) - Molecular Function for ADRA1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004935 adrenergic receptor activity IEA --
GO:0004937 alpha1-adrenergic receptor activity TAS,IBA --
GO:0005515 protein binding IPI 24567387
genes like me logo Genes that share ontologies with ADRA1B: view
genes like me logo Genes that share phenotypes with ADRA1B: view

Animal Models for ADRA1B Gene

MGI Knock Outs for ADRA1B:

Animal Model Products

CRISPR Products

miRNA for ADRA1B Gene

miRTarBase miRNAs that target ADRA1B

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ADRA1B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
  • R&D Systems cDNA Clones for ADRA1B (alpha-1B Adrenergic R/ADRA1B)

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADRA1B Gene

Localization for ADRA1B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADRA1B Gene

Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane, caveola. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADRA1B gene
Compartment Confidence
plasma membrane 5
nucleus 5
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ADRA1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 22120526
GO:0005737 cytoplasm IEA,IDA 24567387
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 1328250
GO:0005901 caveola IEA --
genes like me logo Genes that share ontologies with ADRA1B: view

Pathways & Interactions for ADRA1B Gene

genes like me logo Genes that share pathways with ADRA1B: view

Gene Ontology (GO) - Biological Process for ADRA1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IBA --
GO:0006937 regulation of muscle contraction IEA --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS 2154750
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway TAS 10820200
genes like me logo Genes that share ontologies with ADRA1B: view

No data available for SIGNOR curated interactions for ADRA1B Gene

Drugs & Compounds for ADRA1B Gene

(168) Drugs for ADRA1B Gene - From: DrugBank, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methoxamine Approved Pharma Full agonist, Agonist, stimulator, Target, agonist 3
Phenylephrine Approved Pharma Full agonist, Agonist, agonist, Target 463
Prazosin Approved Pharma Inverse agonist, Antagonist, antagonist, Target 66
Silodosin Approved Pharma Antagonist, Target, antagonist α1-adrenoceptor antagonist 23
Risperidone Approved, Investigational Pharma Antagonist, antagonist, Target SR-2A inhibitor 495

(13) Additional Compounds for ADRA1B Gene - From: HMDB, IUPHAR, Novoseek, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(+)-niguldipine
Antagonist
Promazine 5-sulfoxide
(R)-(-)-Phenylephrine hydrochloride
61-76-7
Tamsulosin hydrochloride
  • ()-(R)-5-(2-((2-(O-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochloride
  • (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochloride
  • 5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide hydrochloride
  • Flomax
  • Harnal
106463-17-6

(5) Tocris Compounds for ADRA1B Gene

Compound Action Cas Number
(R)-(-)-Phenylephrine hydrochloride alpha1 agonist 61-76-7
A 61603 hydrobromide alpha1A agonist 107756-30-9
Cirazoline hydrochloride Selective alpha1 agonist 40600-13-3
RS 100329 hydrochloride Potent, subtype-selective alpha1A antagonist 1215654-26-4
Tamsulosin hydrochloride Selective alpha1A antagonist 106463-17-6

(55) ApexBio Compounds for ADRA1B Gene

Compound Action Cas Number
2-MPMDQ α1-adrenoceptor antagonist,potent and selective 149847-77-8
Acebutolol HCl 34381-68-5
Adrenalone HCl 62-13-5
AH 11110 hydrochloride α1B-AR ligand,subtype-selective 179388-65-9
Alfuzosin HCl α1 adrenoceptor antagonist,functionally uro-selective 81403-68-1
Bambuterol 81732-65-2
Betaxolol βadrenergic receptor blocker 659-18-7
Betaxolol HCl 63659-19-8
Bisoprolol fumarate 104344-23-2
Carvedilol 72956-09-3
Cisatracurium Besylate Neuromuscular-blocking drug 96946-42-8
Clonidine HCl 4205-91-8
Detomidine HCl 90038-01-0
Dexmedetomidine 113775-47-6
Dexmedetomidine HCl 145108-58-3
DL-Adrenaline 329-65-7
Doxazosin Mesylate α1-adrenergic receptor antagonist 77883-43-3
Epinephrine Bitartrate 51-42-3
Epinephrine HCl 55-31-2
Formoterol Hemifumarate 43229-80-7
Guanabenz Acetate 23256-50-0
Indacaterol Maleate 753498-25-8
Isoprenaline HCl 51-30-9
Ivabradine HCl 148849-67-6
Labetalol HCl 32780-64-6
L-Adrenaline 51-43-4
Maprotiline HCl 10347-81-6
Medetomidine HCl 86347-15-1
Methyldopa 555-30-6
Metoprolol Tartrate β1-adrenergic blocking agent 392-17-7
Mirabegron (YM178) 223673-61-8
Naftopidil α1-adrenergic receptor antagonist 57149-07-2
Naftopidil DiHCl 57149-08-3
Naphazoline HCl 550-99-2
Nebivolol 152520-56-4
Nedaplatin 95734-82-0
Oxymetazoline HCl Alpha-1/alpha-2 agonist 2315-02-8
Phenoxybenzamine HCl 63-92-3
Phentolamine Mesylate Alpha 1/2-blocking agent 65-28-1
Phenylephrine HCl 61-76-7
Prazosin HCl α1 and α2B-adrenoceptor antagonist 19237-84-4
Propranolol HCl 318-98-9
Ritodrine HCl β-2 adrenergic receptor agonist 23239-51-2
Salbutamol Sulfate β-2 adrenergic receptor agonist 51022-70-9
Salmeterol xinafoate β2-adrenergic receptor agonist 94749-08-3
Scopine 498-45-3
Silodosin α1-adrenoceptor antagonist 160970-54-7
Synephrine HCl 5985-28-4
Terazosin HCl 70024-40-7
Terbutaline Sulfate 23031-32-5
Tetrahydrozoline HCl 522-48-5
Timolol Maleate 26921-17-5
Tizanidine HCl 64461-82-1
Tolazoline HCl 59-97-2
Xylazine HCl α2 Adrenoceptor agonist 23076-35-9
genes like me logo Genes that share compounds with ADRA1B: view

Drug Products

Transcripts for ADRA1B Gene

mRNA/cDNA for ADRA1B Gene

(7) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ADRA1B Gene

Adrenoceptor alpha 1B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ADRA1B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
  • R&D Systems cDNA Clones for ADRA1B (alpha-1B Adrenergic R/ADRA1B)

Alternative Splicing Database (ASD) splice patterns (SP) for ADRA1B Gene

No ASD Table

Relevant External Links for ADRA1B Gene

GeneLoc Exon Structure for
ADRA1B
ECgene alternative splicing isoforms for
ADRA1B

Expression for ADRA1B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADRA1B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ADRA1B Gene

This gene is overexpressed in Artery - Aorta (x7.3) and Liver (x4.1).

Protein differential expression in normal tissues from HIPED for ADRA1B Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ADRA1B Gene



Protein tissue co-expression partners for ADRA1B Gene

NURSA nuclear receptor signaling pathways regulating expression of ADRA1B Gene:

ADRA1B

SOURCE GeneReport for Unigene cluster for ADRA1B Gene:

Hs.368632

Evidence on tissue expression from TISSUES for ADRA1B Gene

  • Nervous system(4.4)
  • Kidney(2)
genes like me logo Genes that share expression patterns with ADRA1B: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADRA1B Gene

Orthologs for ADRA1B Gene

This gene was present in the common ancestor of animals.

Orthologs for ADRA1B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ADRA1B 33 34
  • 98.52 (n)
cow
(Bos Taurus)
Mammalia ADRA1B 33 34
  • 93.72 (n)
dog
(Canis familiaris)
Mammalia ADRA1B 33 34
  • 92.94 (n)
rat
(Rattus norvegicus)
Mammalia Adra1b 33
  • 90.74 (n)
mouse
(Mus musculus)
Mammalia Adra1b 33 16 34
  • 90.55 (n)
oppossum
(Monodelphis domestica)
Mammalia ADRA1B 34
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ADRA1B 34
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves ADRA1B 33 34
  • 68.89 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 30 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488806 33
  • 64.91 (n)
zebrafish
(Danio rerio)
Actinopterygii adra1bb 33 34
  • 68.06 (n)
ADRA1B (1 of 2) 34
  • 61 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7431 35
  • 44 (a)
DopR2 35
  • 43 (a)
5-HT1B 35
  • 39 (a)
CG6919 35
  • 37 (a)
DopR 35
  • 36 (a)
5-HT1A 35
  • 35 (a)
CG6989 35
  • 35 (a)
5-HT7 35
  • 32 (a)
Oamb 34
  • 25 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C52B11.3 35
  • 34 (a)
dop-4 34
  • 27 (a)
OneToMany
Species where no ortholog for ADRA1B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ADRA1B Gene

ENSEMBL:
Gene Tree for ADRA1B (if available)
TreeFam:
Gene Tree for ADRA1B (if available)

Paralogs for ADRA1B Gene

(19) SIMAP similar genes for ADRA1B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ADRA1B: view

Variants for ADRA1B Gene

Sequence variations from dbSNP and Humsavar for ADRA1B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000027053 -- 159,918,994(+) TCAGG(C/T)CAGAC intron-variant
rs1000044385 -- 159,966,025(+) CCTCC(C/T)TGGCC intron-variant
rs1000104824 -- 159,933,969(+) TAGAC(A/G)GCGTA intron-variant
rs1000114278 -- 159,964,846(+) TGGCA(A/G)TTGTA intron-variant
rs1000144693 -- 159,960,030(+) TGGGA(C/G)TTACG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ADRA1B Gene

Variant ID Type Subtype PubMed ID
dgv1150e214 CNV gain 21293372
dgv3414e59 CNV duplication 20981092
dgv5825n100 CNV gain 25217958
esv22831 CNV loss 19812545
esv3607354 CNV gain 21293372
nsv1015634 CNV gain 25217958
nsv1074340 CNV deletion 25765185
nsv1110451 CNV duplication 24896259
nsv1145074 CNV deletion 24896259
nsv462500 CNV loss 19166990
nsv600166 CNV loss 21841781
nsv830531 CNV loss 17160897
nsv969009 CNV duplication 23825009

Variation tolerance for ADRA1B Gene

Residual Variation Intolerance Score: 31.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.89; 18.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ADRA1B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADRA1B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADRA1B Gene

Disorders for ADRA1B Gene

Relevant External Links for ADRA1B

Genetic Association Database (GAD)
ADRA1B
Human Genome Epidemiology (HuGE) Navigator
ADRA1B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADRA1B

No disorders were found for ADRA1B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADRA1B Gene

Publications for ADRA1B Gene

  1. A genome-wide association study on African-ancestry populations for asthma. (PMID: 19910028) Mathias RA … Barnes KC (The Journal of allergy and clinical immunology 2010) 3 22 45 60
  2. Genomic organization and expression of the human alpha 1B-adrenergic receptor. (PMID: 1328250) Ramarao CS … Graham RM (The Journal of biological chemistry 1992) 3 4 22 60
  3. MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors. (PMID: 24567387) Ogata T … Ueyama T (Proceedings of the National Academy of Sciences of the United States of America 2014) 3 4 60
  4. Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes. (PMID: 22120526) Wright CD … O'Connell TD (Cellular signalling 2012) 3 4 60
  5. Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects. (PMID: 21063774) Parkman HP … Krynetskiy E (Digestive diseases and sciences 2011) 3 45 60

Products for ADRA1B Gene

Sources for ADRA1B Gene

Content
Loading form....