Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADPRM Gene

protein-coding   GIFtS: 41
GCID: GC17P010600

ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese-Dependent

(Previous name: chromosome 17 open reading frame 48)
(Previous symbol: C17orf48)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese-Dependent1 2     ADP-Ribose/CDP-Alcohol Pyrophosphatase2
C17orf481 2 3     Manganese-Dependent ADP-Ribose/CDP-Alcohol Diphosphatase2
ADPRibase-Mn2 3     EC 3.6.1.133
CDP-Choline Phosphohydrolase2 3     EC 3.6.1.163
Chromosome 17 Open Reading Frame 481     EC 3.6.1.533
NBLA038312     

External Ids:    HGNC: 309251   Entrez Gene: 569852   Ensembl: ENSG000001702227   UniProtKB: Q3LIE53   

Export aliases for ADPRM gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ADPRM Gene: 
ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent) is a protein-coding gene. Diseases associated with ADPRM include alcoholism, and neuroblastoma, and among its related super-pathways are Glycerophospholipid biosynthesis and Pyrimidine metabolism. GO annotations related to this gene include CDP-glycerol diphosphatase activity and ADP-ribose diphosphatase activity.

UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5
Function: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other
non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the
second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ADPRM
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ADPRM

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADPRM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

ADPRM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADPRM gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P010600:  view genomic region     (about GC identifiers)

Start:
10,600,911 bp from pter      End:
10,614,875 bp from pter
Size:
13,965 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5 (See protein sequence)
Recommended Name: Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase  
Size: 342 amino acids; 39529 Da
Cofactor: Magnesium (By similarity)
Subunit: Monomer (By similarity)
Sequence caution: Sequence=AAF87317.1; Type=Frameshift; Positions=Several;
Secondary accessions: A8K9B4 D3DTS4 Q9BVD4 Q9NRU8
Alternative splicing: 2 isoforms:  Q3LIE5-1   Q3LIE5-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ADPRM: NX_Q3LIE5

Explore proteomics data for ADPRM at MOPED 

ADPRM Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

ADPRM Protein Expression

REFSEQ proteins: NP_064618.3  
ENSEMBL proteins: 
 ENSP00000369099   ENSP00000431622   ENSP00000463134  

Human Recombinant Protein Products for ADPRM: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for ADPRM
OriGene Protein Over-expression Lysate for ADPRM
OriGene MassSpec for ADPRM 
OriGene Custom Protein Services for ADPRM
GenScript Custom Purified and Recombinant Proteins Services for ADPRM
Novus Biologicals ADPRM Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 


ADPRM Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for ADPRM
GenScript Custom Superior Antibodies Services for ADPRM
Novus Biologicals ADPRM Antibodies
Abcam antibodies for ADPRM
Browse Antibodies at Cloud-Clone Corp. 
Search ThermoFisher Antibodies for ADPRM
LSBio Antibodies in human, mouse, rat for ADPRM 

Assay Products for ADPRM: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for ADPRM
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ADPRM
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp. 
Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR004843 Metallo_PEstase_dom

Graphical View of Domain Structure for InterPro Entry Q3LIE5

ProtoNet protein and cluster: Q3LIE5

UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5
Similarity: Belongs to the ADPRibase-Mn family


ADPRM for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: ADPRM_HUMAN, Q3LIE5
Function: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other
non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the
second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By
similarity)
Catalytic activity: CDP-choline + H(2)O = CMP + phosphocholine
Catalytic activity: ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate
Catalytic activity: CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate

     Enzyme Numbers (IUBMB): EC 3.6.1.161 EC 3.6.1.131 EC 3.6.1.531

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016787hydrolase activity ----
GO:0046872metal ion binding IEA--
GO:0047631ADP-ribose diphosphatase activity IEA--
GO:0047734CDP-glycerol diphosphatase activity IEA--
     
ADPRM for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for ADPRM:
 Increased G2M DNA content 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for ADPRM 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ADPRM

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ADPRM 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ADPRM 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ADPRM
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ADPRM
SwitchGear 3'UTR luciferase reporter plasmidADPRM 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for ADPRM
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADPRM

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ADPRM
Sirion Biotech Customized adenovirus for overexpression of ADPRM

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for ADPRM (see all 7)
OriGene ORF clones in mouse, rat for ADPRM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for ADPRM
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADPRM
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM
Sirion Biotech Customized lentivirus for stable overexpression of ADPRM 
                     Customized lentivirus expression plasmids for stable overexpression of ADPRM 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ADPRM
Search LifeMap BioReagents cell lines for ADPRM
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for ADPRM About                                                                                                See pathways by source

SuperPathContained pathways About
1Glycerophospholipid biosynthesis
Glycerophospholipid metabolism0.62
2Purine metabolism
Purine metabolism0.38

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



2         Kegg Pathways  (Kegg details for ADPRM):
    Purine metabolism
Glycerophospholipid metabolism


ADPRM for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADPRM

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

5/13 Interacting proteins for ADPRM (ENSP000003690994) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
InteractantInteraction Details
GeneCardExternal ID(s)
AGPAT6ENSP000003801844STRING: ENSP00000380184
AGPAT9ENSP000002644094STRING: ENSP00000264409
GPAMENSP000002652764STRING: ENSP00000265276
GPAT2ENSP000003525474STRING: ENSP00000352547
GPD1ENSP000003011494STRING: ENSP00000301149
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ADPRM

Search CenterWatch for drugs/clinical trials and news about ADPRM

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ADPRM gene: 
NM_020233.4  

Unigene Cluster for ADPRM:

ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
Hs.47668  [show with all ESTs]
Unigene Representative Sequence: NM_020233
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000379774(uc002gmt.3 uc010vvg.1) ENST00000468843(uc002gmu.3 uc002gmv.3)
ENST00000527582
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ADPRM
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ADPRM
SwitchGear 3'UTR luciferase reporter plasmidADPRM 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for ADPRM
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADPRM
Clone
Products:
     
OriGene clones in human, mouse for ADPRM (see all 7)
OriGene ORF clones in mouse, rat for ADPRM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for ADPRM
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADPRM
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM
Sirion Biotech Customized lentivirus for stable overexpression of ADPRM 
                     Customized lentivirus expression plasmids for stable overexpression of ADPRM 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ADPRM
OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat ADPRM
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADPRM
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADPRM

Additional mRNA sequence: 

AB073393.1 AF168715.1 AK292629.1 

5 DOTS entries:

DT.102830571  DT.100751907  DT.411972  DT.120908282  DT.120908328 

24/84 AceView cDNA sequences (see all 84):

W30757 AW170606 BQ924013 AA478606 CK826536 BI819803 CR605738 CD672249 
BF984506 CR612920 AL527655 AW770561 AA479340 BG282949 BM703528 BX110576 
BG026561 BM792421 BI914385 W76468 AA705057 AI168727 AI016298 NM_020233 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for ADPRM    About this scheme

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1:                              
SP2:              -               
SP3:                              


ECgene alternative splicing isoforms for ADPRM

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ADPRM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ADPRM Expression
About this image


See ADPRM Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ADPRM

SOURCE GeneReport for Unigene cluster: Hs.47668
    SABiosciences Custom PCR Arrays for ADPRM
Primer
Products:
OriGene qPCR primer pairs and template standards for ADPRM
OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat ADPRM
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADPRM
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADPRM
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ADPRM gene from 7/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Adprm1 , 5 RIKEN cDNA 2310004I24 gene5
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent1
84.96(n)1
85.25(a)1
  11 (40.59 cM)5
663581  NM_025510.31  NP_079786.21 
 670379055 
chicken
(Gallus gallus)
Aves C18H17orf481 chromosome 18 open reading frame, human C17orf48 65.81(n)
66.49(a)
  768578  XM_001231600.2  XP_001231601.2 
lizard
(Anolis carolinensis)
Reptilia ADPRM6
Uncharacterized protein
56(a)
1 ↔ 1
2(108823636-108829955)
African clawed frog
(Xenopus laevis)
Amphibia mds006-prov2 x 006 protein 76.62(n)    BC056093.1 
zebrafish
(Danio rerio)
Actinopterygii zgc642132 hypothetical protein MGC64213 71.87(n)   393393  BC054642.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G247301 calcineurin-like phosphoesterase family protein 49.28(n)
40.47(a)
  828575  NM_001125573.1  NP_001119045.1 
rice
(Oryza sativa)
Liliopsida Os.316562 Oryza sativa (japonica cultivar-group) cDNA clone0 more 69.65(n)    AK069836.1 


ENSEMBL Gene Tree for ADPRM (if available)
TreeFam Gene Tree for ADPRM (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/297 SNPs in ADPRM are shown (see all 297)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs732876291,2
C,F--10602967(+) CTCCCG/ATGTAG 1 -- int16Minor allele frequency- A:0.46WA NA CSA EA 248
rs1145092891,2
F--10602992(+) GCGTGC/TCACCA 1 -- int11Minor allele frequency- T:0.02WA 118
rs1418132931,2
--10603064(+) TAGGAC/TGGTCT 1 -- int10--------
rs1912916441,2
--10603084(+) GACATC/GGTGAT 1 -- int10--------
rs1835967841,2
--10603100(+) CGCCTC/TGGCCT 1 -- int10--------
rs1461689241,2
C--10603153(+) CCCAAC/TTTAGA 1 -- int10--------
rs25201621,2
C,F,H--10603321(-) CAAAAA/TTGAAG 1 -- int16Minor allele frequency- T:0.09NS EA WA 540
rs25201611,2
C,F,A,H--10603421(-) GCATAC/TGTTTT 1 -- int117Minor allele frequency- T:0.48NA EA WA CSA 876
rs25201601,2
C,F,A,H--10603423(-) CAGCAT/AATGTT 1 -- int17Minor allele frequency- A:0.07NS EA WA 650
rs1389985621,2
C--10603543(+) GAAATC/GATACT 1 -- int10--------

HapMap Linkage Disequilibrium report for ADPRM (10600911 - 10614875 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ADPRM: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing ADPRM
DNA2.0 Custom Variant and Variant Library Synthesis for ADPRM

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
2 diseases for ADPRM:    About MalaCards
alcoholism    neuroblastoma


ADPRM for disorders           About GeneDecksing


Export disorders for ADPRM gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ADPRM gene integrated from 9 sources:
(articles sorted by number of sources associating them with ADPRM)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase : a novel metallophosphoesterase family preferentially expressed in rodent immu ne cells. (PubMed id 18352857)1, 3 Canales J....Costas M.J. (2008)
  2. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  6. Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PubMed id 12880961)2 Ohira M.... Nakagawara A. (2003)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 56985 HGNC: 30925 AceView: MDS006 Ensembl:ENSG00000170222 euGenes: HUgn56985
ECgene: ADPRM Kegg: 56985 H-InvDB: ADPRM

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for ADPRM Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for ADPRM gene:
Search GeneIP for patents involving ADPRM

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ADPRM  
 OriGene qPCR primer pairs and template standards for ADPRM   OriGene Protein Over-expression Lysate for ADPRM  
 OriGene MassSpec something-or-other for ADPRM   OriGene clones in human, mouse for ADPRM  
 OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM   OriGene Purified Protein for ADPRM  
 OriGene ORF clones in mouse, rat for ADPRM   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for ADPRM   OriGene Custom Protein Services for ADPRM  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADPRM
 QIAGEN SeqTarget long-range PCR primers for resequencing ADPRM
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADPRM
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADPRM
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADPRM
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADPRM
 GenScript Custom Purified and Recombinant Proteins Services for ADPRM GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ADPRM
 GenScript Custom Assay Services for ADPRM GenScript Custom Superior Antibodies Services for ADPRM
 GenScript Custom overexpressing Cell Line Services for ADPRM CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Search Regulatory tfbs for ADPRM
 Search Chromatin IP Primers for ADPRM
 Search RT2 qPCR Primer Assays in human, mouse, rat ADPRM
 Search GNC Networks for ADPRM
 SABiosciences Custom PCR Arrays for ADPRM
 Search Tocris compounds for ADPRM
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 ADPRM antibodies
 ADPRM lysates
 Antibodies for ADPRM
 See all of Abcam's Antibodies, Kits and Proteins for ADPRM
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.
 Search LifeMap BioReagents cell lines for ADPRM
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM
 SwitchGear 3'UTR luciferase reporter plasmids for ADPRM
 Browse SwitchGear Promoter luciferase reporter plasmids for ADPRM
 Search ThermoFisher Antibodies for ADPRM
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM
 inGenious Targeting Laboratory - Custom generated mouse model solutions for ADPRM
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ADPRM
Customized:
 lentivirus for stable overexpression of ADPRM
 lentivirus expression plasmids for stable overexpression of ADPRM
 adenovirus for overexpression of ADPRM
 LSBio Antibodies in human, mouse, rat for ADPRM
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      ADPRM gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4