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ADPRM Gene

protein-coding   GIFtS: 39
GCID: GC17P010600

ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese-Dependent

(Previous name: chromosome 17 open reading frame 48)
(Previous symbol: C17orf48)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese-Dependent1 2     ADP-Ribose/CDP-Alcohol Pyrophosphatase2
C17orf481 2 3     Manganese-Dependent ADP-Ribose/CDP-Alcohol Diphosphatase2
ADPRibase-Mn2 3     EC 3.6.1.133
CDP-Choline Phosphohydrolase2 3     EC 3.6.1.163
Chromosome 17 Open Reading Frame 481     EC 3.6.1.533
NBLA038312     

External Ids:    HGNC: 309251   Entrez Gene: 569852   Ensembl: ENSG000001702227   UniProtKB: Q3LIE53   

Export aliases for ADPRM gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ADPRM Gene:
ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent) is a protein-coding gene. Diseases associated with ADPRM include neuroblastoma. GO annotations related to this gene include CDP-glycerol diphosphatase activity and ADP-ribose diphosphatase activity.

UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5
Function: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other
non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the
second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010718.17  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ADPRM
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ADPRM

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADPRM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

ADPRM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADPRM gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P010600:  view genomic region     (about GC identifiers)

Start:
10,600,911 bp from pter      End:
10,614,875 bp from pter
Size:
13,965 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5 (See protein sequence)
Recommended Name: Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase  
Size: 342 amino acids; 39529 Da
Cofactor: Magnesium (By similarity)
Subunit: Monomer (By similarity)
Sequence caution: Sequence=AAF87317.1; Type=Frameshift; Positions=Several;
Secondary accessions: A8K9B4 D3DTS4 Q9BVD4 Q9NRU8
Alternative splicing: 2 isoforms:  Q3LIE5-1   Q3LIE5-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ADPRM: NX_Q3LIE5

Explore proteomics data for ADPRM at MOPED


See ADPRM Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_064618.3  
ENSEMBL proteins: 
 ENSP00000369099   ENSP00000431622   ENSP00000477021  

ADPRM Human Recombinant Protein Products:

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Novus Biologicals ADPRM Lysate
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ADPRM Antibody Products:

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Novus Biologicals ADPRM Antibodies
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LSBio Antibodies in human, mouse, rat for ADPRM

ADPRM Assay Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR004843 PEstase_dom

Graphical View of Domain Structure for InterPro Entry Q3LIE5

ProtoNet protein and cluster: Q3LIE5

UniProtKB/Swiss-Prot: ADPRM_HUMAN, Q3LIE5
Similarity: Belongs to the ADPRibase-Mn family


ADPRM for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ADPRM_HUMAN, Q3LIE5
Function: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other
non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the
second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By
similarity)
Catalytic activity: CDP-choline + H(2)O = CMP + phosphocholine
Catalytic activity: ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate
Catalytic activity: CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate

     Enzyme Numbers (IUBMB): EC 3.6.1.161 EC 3.6.1.131 EC 3.6.1.531

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016787hydrolase activity ----
GO:0046872metal ion binding IEA--
GO:0047631ADP-ribose diphosphatase activity IEA--
GO:0047734CDP-glycerol diphosphatase activity IEA--
     
ADPRM for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for ADPRM:
 Increased G2M DNA content 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADPRM
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ADPRM

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ADPRM
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ADPRM

miRNA
Products:
    
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SwitchGear 3'UTR luciferase reporter plasmidADPRM 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat ADPRM

Gene Editing
Products:
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ADPRM About                                                                                                See pathways by source

SuperPathContained pathways About
1Glycerophospholipid biosynthesis
Glycerophospholipid metabolism0.62
2Purine metabolism (KEGG)
Purine metabolism0.38

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



2 Kegg Pathways  (Kegg details for ADPRM):
    Purine metabolism
Glycerophospholipid metabolism


ADPRM for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ADPRM
Interactions:

    Search GeneGlobe Interaction Network for ADPRM

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

Selected Interacting proteins for ADPRM (ENSP000003690994) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
InteractantInteraction Details
GeneCardExternal ID(s)
AGPAT6ENSP000003801844STRING: ENSP00000380184
AGPAT9ENSP000002644094STRING: ENSP00000264409
GPAMENSP000002652764STRING: ENSP00000265276
GPAT2ENSP000003525474STRING: ENSP00000352547
GPD1ENSP000003011494STRING: ENSP00000301149
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ADPRM



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for ADPRM gene: 
NM_020233.4  

Unigene Cluster for ADPRM:

ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
Hs.47668  [show with all ESTs]
Unigene Representative Sequence: NM_020233
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000379774(uc002gmt.3 uc010vvg.1) ENST00000468843(uc002gmu.3 uc002gmv.3)
ENST00000527582 ENST00000609540
miRNA
Products:
     
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SwitchGear 3'UTR luciferase reporter plasmidADPRM 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat ADPRM
Clone
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADPRM
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ADPRM
OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM
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  QuantiTect SYBR Green Assays in human, mouse, rat ADPRM
  QuantiFast Probe-based Assays in human, mouse, rat ADPRM

Additional mRNA sequence: 

AB073393.1 AF168715.1 AK292629.1 

5 DOTS entries:

DT.102830571  DT.100751907  DT.411972  DT.120908282  DT.120908328 

Selected AceView cDNA sequences (see all 84):

CR605738 W30757 BF984506 BQ924013 CR612920 BG282949 CD672249 AW170606 
BX110576 AW770561 BM792421 AA478606 AA479340 W76468 BI819803 BM703528 
BI914385 CK826536 BG026561 AL527655 AA705057 BG436602 AI193664 BE536660 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for ADPRM    About this scheme

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1:                              
SP2:              -               
SP3:                              


ECgene alternative splicing isoforms for ADPRM

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ADPRM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ADPRM Expression
About this image

ADPRM Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ADPRM Protein Expression

Genevestigator expression for ADPRM

SOURCE GeneReport for Unigene cluster: Hs.47668
    Custom PCR Arrays for ADPRM
Primer
Products:
OriGene qPCR primer pairs and template standards for ADPRM
OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM
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QuantiFast Probe-based Assays in human, mouse, rat ADPRM
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for ADPRM gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Adprm1 , 5 RIKEN cDNA 2310004I24 gene5
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent1
84.9(n)1
85(a)1
  11 (40.59 cM)5
663581  NM_025510.31  NP_079786.21 
 670379055 
chicken
(Gallus gallus)
Aves C17ORF481 chromosome 18 open reading frame, human C17orf48 65.01(n)
65.17(a)
  768578  XM_001231600.3  XP_001231601.3 
lizard
(Anolis carolinensis)
Reptilia ADPRM6
ADP-ribose/CDP-alcohol diphosphatase, manganese-de...
57(a)
1 ↔ 1
2(108823636-108829955)
African clawed frog
(Xenopus laevis)
Amphibia mds006-prov2 x 006 protein 76.62(n)    BC056093.1 
zebrafish
(Danio rerio)
Actinopterygii zgc642132 hypothetical protein MGC64213 71.87(n)   393393  BC054642.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G247301 AT4G24730 49.61(n)
40.8(a)
  828575  NM_001125573.1  NP_001119045.1 
rice
(Oryza sativa)
Liliopsida Os.316562 Oryza sativa (japonica cultivar-group) cDNA clone0 more 69.65(n)    AK069836.1 


ENSEMBL Gene Tree for ADPRM (if available)
TreeFam Gene Tree for ADPRM (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ADPRM (see all 297)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs732876291,2
C,F--10602967(+) CTCCCG/ATGTAG 1 -- int16Minor allele frequency- A:0.46WA NA CSA EA 248
rs1145092891,2
F--10602992(+) GCGTGC/TCACCA 1 -- int11Minor allele frequency- T:0.02WA 118
rs1418132931,2
--10603064(+) TAGGAC/TGGTCT 1 -- int10--------
rs1912916441,2
--10603084(+) GACATC/GGTGAT 1 -- int10--------
rs1835967841,2
--10603100(+) CGCCTC/TGGCCT 1 -- int10--------
rs1461689241,2
C--10603153(+) CCCAAC/TTTAGA 1 -- int10--------
rs25201621,2
C,F,H--10603321(-) CAAAAA/TTGAAG 1 -- int16Minor allele frequency- T:0.09NS EA WA 540
rs25201611,2
C,F,A,H--10603421(-) GCATAC/TGTTTT 1 -- int117Minor allele frequency- T:0.48NA EA WA CSA 876
rs25201601,2
C,F,A,H--10603423(-) CAGCAT/AATGTT 1 -- int17Minor allele frequency- A:0.07NS EA WA 650
rs1389985621,2
C--10603543(+) GAAATC/GATACT 1 -- int10--------

HapMap Linkage Disequilibrium report for ADPRM (10600911 - 10614875 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ADPRM: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ADPRM
DNA2.0 Custom Variant and Variant Library Synthesis for ADPRM

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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1 disease for ADPRM:    About MalaCards
neuroblastoma


ADPRM for disorders           About GeneDecksing


Export disorders for ADPRM gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ADPRM gene integrated from 10 sources:
(articles sorted by number of sources associating them with ADPRM)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells. (PubMed id 18352857)1, 3 Canales J....Costas M.J. (Biochem. J. 2008)
  2. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  3. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
  4. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PubMed id 19460752)1 Yeung M.L....Jeang K.T. (J. Biol. Chem. 2009)
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  8. Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PubMed id 12880961)2 Ohira M.... Nakagawara A. (Cancer Lett. 2003)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 56985 HGNC: 30925 AceView: MDS006 Ensembl:ENSG00000170222 euGenes: HUgn56985
ECgene: ADPRM Kegg: 56985 H-InvDB: ADPRM

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ADPRM Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ADPRM gene:
Search GeneIP for patents involving ADPRM

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ADPRM  
 OriGene qPCR primer pairs and template standards for ADPRM   OriGene Protein Over-expression Lysate for ADPRM  
 OriGene MassSpec something-or-other for ADPRM   OriGene clones in human, mouse for ADPRM  
 OriGene qSTAR qPCR primer pairs in human, mouse for ADPRM   OriGene Purified Protein for ADPRM  
 OriGene ORF clones in mouse, rat for ADPRM   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for ADPRM   OriGene Custom Protein Services for ADPRM  

 
 
 Block miRNA regulation of human, mouse, rat ADPRM using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ADPRM
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADPRM Predesigned siRNA for gene silencing in human, mouse, rat ADPRM
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 Custom PCR Arrays for ADPRM Search Chromatin IP Primers for ADPRM
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ADPRM Search GeneGlobe Interaction Network for ADPRM
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 GenScript Custom Purified and Recombinant Proteins Services for ADPRM GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ADPRM
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 Search Tocris compounds for ADPRM
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
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 Search for Antibodies for ADPRM at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for ADPRM
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 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
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 Browse ESI BIO Cell Lines and PureStem Progenitors for ADPRM
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADPRM
 SwitchGear 3'UTR luciferase reporter plasmids for ADPRM
 Browse SwitchGear Promoter luciferase reporter plasmids for ADPRM
 Search ThermoFisher Antibodies for ADPRM
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADPRM
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADPRM
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ADPRM
 LSBio Antibodies in human, mouse, rat for ADPRM
Customized transgenic rodents for:
 Humanization
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 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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