Aliases for ADPRH Gene
External Ids for ADPRH Gene
Previous GeneCards Identifiers for ADPRH Gene
The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, May 2014]
GeneCards Summary for ADPRH Gene
ADPRH (ADP-Ribosylarginine Hydrolase) is a Protein Coding gene. Diseases associated with ADPRH include Glycine N-Methyltransferase Deficiency and Parkinson Disease Susceptibility. GO annotations related to this gene include magnesium ion binding and ADP-ribosylarginine hydrolase activity. An important paralog of this gene is ADPRHL1.
UniProtKB/Swiss-Prot for ADPRH Gene
Catalyzes the reverse reaction of mono-ADP-ribosylation.