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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADPGK Gene

protein-coding   GIFtS: 56
GCID: GC15M073043

ADP-dependent glucokinase

 Explore 7 diseases affiliated with
ADPGK via our new
 Human Malady Compendium 
Biological research products
for ADPGK
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
ADP-Dependent Glucokinase1 2     ATP-Dependent Glucokinase2
ADP-GK1 2 3     RbBP-353
DKFZp434B1951     EC 2.7.1.1473
2610017G09Rik2     RbBP-353

External Ids:    HGNC: 252501   Entrez Gene: 834402   Ensembl: ENSG000001593227   OMIM: 6118615   UniProtKB: Q9BRR63   
ORGUL members:         
NONCODE:n406449 n406450    

Export aliases for ADPGK gene to outside databases

Previous GC identifers: GC15M070830 GC15M049874


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ADPGK:
ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role
in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 (PubMed 14975750)).(supplied by OMIM, Mar
2008)

UniProtKB/Swiss-Prot: ADPGK_HUMAN, Q9BRR6
Function: Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and
CDP can replace ADP, but with reduced efficiency (By similarity)

Gene Wiki entry for ADPGK (ADP-specific glucokinase)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ADPGK gene promoter:
         AML1a   MyoD   AP-4   E47   N-Myc   HEN1   CP2   HOXA5   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADPGK promoter sequence
   Search SABiosciences Chromatin IP Primers for ADPGK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADPGK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24.1   Ensembl cytogenetic band:  15q24.1   HGNC cytogenetic band: 15q24.1

ADPGK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADPGK gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M073043:  view genomic region     (about GC identifiers)

Start:
73,043,708 bp from pter      End:
73,078,187 bp from pter
Size:
34,480 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

  • n406450
  • n406449
73043707 73059917 73076126 chr15

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ADPGK_HUMAN, Q9BRR6 (See protein sequence)
Recommended Name: ADP-dependent glucokinase precursor  
Size: 497 amino acids; 54089 Da
Cofactor: Binds 1 magnesium ion per subunit (By similarity)
Subunit: Monomer (By similarity)
Subcellular location: Secreted (Potential)
Secondary accessions: Q49AU7 Q8NBI1 Q8WZ90 Q96NF8 Q9H0A7
Alternative splicing: 6 isoforms:  Q9BRR6-1   Q9BRR6-2   Q9BRR6-3   Q9BRR6-4   Q9BRR6-5   Q9BRR6-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ADPGK: NX_Q9BRR6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BRR6

  • ADPGK Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_112574.3  
    ENSEMBL proteins: 
     ENSP00000457572   ENSP00000458102   ENSP00000454707   ENSP00000312250   ENSP00000456387  
     ENSP00000454304   ENSP00000457447   ENSP00000457175   ENSP00000454367   ENSP00000397210  
     ENSP00000397694  

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    Uscn Proteins for ADPGK

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--


    ADPGK for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ADPGK for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007666 ADP_PFK/GK

    Graphical View of Domain Structure for InterPro Entry Q9BRR6

    ProtoNet protein and cluster: Q9BRR6

    UniProtKB/Swiss-Prot: ADPGK_HUMAN, Q9BRR6
    Similarity: Belongs to the ADP-dependent glucokinase family
    Similarity: Contains 1 ADPK (ADP-dependent kinase) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ADPGK_HUMAN, Q9BRR6
    Function: Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and
    CDP can replace ADP, but with reduced efficiency (By similarity)
    Catalytic activity: ADP + D-glucose = AMP + D-glucose 6-phosphate

    Enzyme Number (IUBMB): EC 2.7.1.1471

    miRNA
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    miRTarBase miRNAs that target ADPGK:
    hsa-mir-30a (MIRT005179), hsa-mir-1 (MIRT001393)

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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate ADPGK (see all 15):
    hsa-miR-203 hsa-miR-3163 hsa-miR-647 hsa-miR-3673 hsa-miR-206 hsa-miR-1 hsa-miR-340 hsa-miR-3667-3p
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016301kinase activity ----
    GO:0016773phosphotransferase activity, alcohol group as acceptor ----
    GO:0043843ADP-specific glucokinase activity IEA--
    GO:0046872metal ion binding IEA--


    ADPGK for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glycolysis and gluconeogenesis (short map)
    Glycolysis / Gluconeogenesis0.41
    2Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    2         Kegg Pathways  (Kegg details for ADPGK):
        Glycolysis / Gluconeogenesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: ADPGK_HUMAN, Q9BRR6
    Pathway: Carbohydrate degradation; glycolysis


    ADPGK for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADPGK

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/15 Interacting proteins for ADPGK (Q9BRR62, 3 ENSP000003122504) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    GDF9O603832, 3MINT-65317 I2D: score=4 
    TADA3O755282, 3MINT-63211 I2D: score=4 
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2876906 I2D: score=3 STRING: ENSP00000357292
    GPIENSP000003488774STRING: ENSP00000348877
    GALMENSP000002722524STRING: ENSP00000272252
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process ----
    GO:0006096glycolysis IEA--


    ADPGK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ADPGK for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ADPGK

    5 HMDB Compounds for ADPGK    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    D-Glucose(+)-Glucose (see all 23)50-99-7--
    Glucose 6-phosphateD(+)-Glucopyranose 6-phosphate (see all 11)56-73-5--
    MagnesiumMagnesium (see all 2)7439-95-4--
    4 Novoseek chemical compound relationships for ADPGK gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    polyphosphate 88.5 6 8380966 (3), 8381043 (2), 8390296 (1)
    glucose 6-phosphate 54.5 1 8703950 (1)
    atp 53.2 19 8380966 (4), 8381043 (4), 15466045 (3), 8390296 (2) (see all 6)
    glucose 29.1 1 15466045 (1)

    Search CenterWatch for drugs/clinical trials and news about ADPGK 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ADPGK gene: 
    NM_031284.4  

    Unigene Cluster for ADPGK:

    ADP-dependent glucokinase
    Hs.654636  [show with all ESTs]
    Unigene Representative Sequence: AL832254
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000569693 ENST00000567941(uc002avi.4) ENST00000569534 ENST00000311669(uc010ukw.2 uc002avf.4 uc002avh.4 uc002avg.4)
    ENST00000562621(uc002ave.4) ENST00000563907 ENST00000569517 ENST00000567733
    ENST00000565814 ENST00000569058 ENST00000566509 ENST00000562286 ENST00000562823
    ENST00000443764 ENST00000456471

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    Additional cDNA sequence: 

    AF204270.1 AK055526.1 AK057651.1 AK075560.1 AK293282.1 AK294391.1 AL136873.1 AL832254.1 
    BC006112.1 BC018074.1 BC044589.1 CR533447.1 NR_023318.1 NR_023319.1 

    17 DOTS entries:

    DT.95211797  DT.100029745  DT.101960584  DT.100824229  DT.121041282  DT.95366795  DT.121041366  DT.91698565 
    DT.92440224  DT.100824227  DT.117523  DT.91979152  DT.100824228  DT.100824230  DT.121041299  DT.40238368 
    DT.95211819 

    24/291 AceView cDNA sequences (see all 291):

    AA999949 AI500132 BE301664 BE018185 BF061730 AL136873 Z38583 BF058653 
    BU622523 AW991457 AA300494 CA430898 BM822357 CD742646 AW167831 AL832254 
    AI801918 AW449075 CB528349 AL135726 AA042887 AA634247 AI922138 BM929748 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for ADPGK (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c · 9d · 9e ^ 10 ^
    SP1:                                                  -     -     -     -                                   -     -     -     -                                 
    SP2:                                            -     -     -     -     -                                   -     -     -     -                                 
    SP3:                                            -     -     -     -     -                                   -     -     -     -                                 
    SP4:                                            -     -     -     -     -     -     -     -                 -     -     -     -                                 
    SP5:                                            -     -     -     -     -                                   -     -     -     -     -     -     -     -     -   

    ExUns: 11a · 11b · 11c ^ 12a · 12b · 12c · 12d ^ 13
    SP1:                                                
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for ADPGK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ADPGK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTATATATTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ADPGK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ADPGK

    SOURCE GeneReport for Unigene cluster: Hs.654636
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ADPGK gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Adpgk1 , 5 ADP-dependent glucokinase1, 5 89.41(n)1
    91.7(a)1
      9 (32.01 cM)5
    721411  NM_028121.21  NP_082397.11 
     592915725 
    chicken
    (Gallus gallus)
    Aves ADPGK1 ADP-dependent glucokinase 74.13(n)
    77.82(a)
      415317  XM_413705.3  XP_413705.2 
    lizard
    (Anolis carolinensis)
    Reptilia ADPGK6
    --
    74(a)
    1 ↔ 1
    GL343872.1(37158-44843)
    zebrafish
    (Danio rerio)
    Actinopterygii adpgk1 ADP-dependent glucokinase 64.49(n)
    64.49(a)
      557919  NM_001079965.1  NP_001073434.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG66506
    --
    27(a)
    1 ↔ 1
    3L(14024550-14027740)
    worm
    (Caenorhabditis elegans)
    Secernentea C50D2.71 Protein C50D2.7 47.69(n)
    38.55(a)
      173393  NM_061256.3  NP_493657.2 


    ENSEMBL Gene Tree for ADPGK (if available)
    TreeFam Gene Tree for ADPGK (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ADPGK gene
    1 SIMAP similar gene for ADPGK using alignment to 7 protein entries:     ADPGK_HUMAN (see all proteins):
    DKFZp667C1917

    ADPGK for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ADPGK
    PGOHUM00000246844


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/500 NCBI SNPs in ADPGK are shown (see all 500    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857224261,2
    --73043229(+) AGATTG/TCCTTA 3 -- int10--------
    rs1906325841,2
    --73043258(+) GCTTTA/GAGTTA 3 -- int10--------
    rs31841831,2
    C--73043903(-) AATTTG/TTTTTT 3 -- ut31 nc-transcript-variant2Minor allele frequency- T:0.00MN NA 186
    rs1808600411,2
    --73044045(+) AAAGCA/GTGATC 3 -- ut31 nc-transcript-variant0--------
    rs1427504471,2
    --73044132(+) CTGCCA/CTCATA 3 -- nc-transcript-variantut310--------
    rs1396727451,2
    --73044188(+) TTGAG-/AGCAGGAG 3 -- ut31 nc-transcript-variant0--------
    rs1849281061,2
    --73044222(+) AAATAC/TTGTCA 3 -- ut31 nc-transcript-variant0--------
    rs1886181041,2
    --73044265(+) CCATGA/GGCACT 3 -- nc-transcript-variantut310--------
    rs1135211781,2
    --73044399(+) GGTGAC/AGAAGT 3 -- nc-transcript-variantut311Minor allele frequency- A:0.50CSA 2
    rs1812749751,2
    --73044506(+) TCATTA/GGCTAA 3 -- nc-transcript-variantut310--------

    HapMap Linkage Disequilibrium report for ADPGK (73043708 - 73078187 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ADPGK
         1 CNV: 3967

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ADPGK for disorders           About GeneDecksing

    OMIM gene information: 611861    OMIM disorders: --

    7 diseases for ADPGK:    About MalaCards
    type 1 diabetes mellitus    diabetes mellitus    hyperglycemia    tuberculosis
    ataxia    mycobacterium tuberculosis    alcoholism

    1 Novoseek disease relationship for ADPGK gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tuberculosis 37.7 2 8390296 (1), 8381043 (1)

    Human Genome Epidemiology (HuGE) Navigator: ADPGK (1 document)

    Export disorders for ADPGK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ADPGK gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with ADPGK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Expression and role in glycolysis of human ADP-depende nt glucokinase. (PubMed id 22219026)1 Richter S....Wilson W.R. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    9. Clinical heterogeneity in monogenic diabetes caused b y mutations in the glucokinase gene (GCK-MODY). (PubMed id 19903754)1 Cuesta-MuA+oz A.L....Matschinsky F.M. (2010)
    10. Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus. (PubMed id 19309449)1 Codner E....Chung W.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83440 HGNC: 25250 AceView: ADPGK Ensembl:ENSG00000159322 euGenes: HUgn83440
    ECgene: ADPGK Kegg: 83440 H-InvDB: ADPGK

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ADPGK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ADPGK gene:
    Search GeneIP for patents involving ADPGK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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