Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ADORA2A-AS1 Gene

Subcategory (RNA class) for ADORA2A-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for ADORA2A-AS1 Gene

  • ADORA2A Antisense RNA 1 2 3 4 5
  • C22orf45 3 4
  • Chromosome 22 Open Reading Frame 45 2
  • ADORA2A Antisense Gene Protein 1 4

External Ids for ADORA2A-AS1 Gene

Previous HGNC Symbols for ADORA2A-AS1 Gene

  • C22orf45

Previous GeneCards Identifiers for ADORA2A-AS1 Gene

  • GC22M024826
  • GC22M024955
  • GC22M025178
  • GC22M024563
  • GC22M024667
  • GC22M025051
  • GC22M025468
  • GC22M025651

Summaries for ADORA2A-AS1 Gene

GeneCards Summary for ADORA2A-AS1 Gene

ADORA2A-AS1 (ADORA2A Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADORA2A-AS1 Gene

Genomics for ADORA2A-AS1 Gene

Regulatory Elements for ADORA2A-AS1 Gene

Enhancers for ADORA2A-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G024449 1.1 Ensembl ENCODE dbSUPER 26.6 +44.4 44408 1.5 BCOR ZMYM3 REST RAD21 RAD51 SMARCA4 POLR2A ZNF366 ADNP KDM1A UPB1 ADORA2A-AS1 ADORA2A SPECC1L ENSG00000228923 GC22P024441 GC22P024440
GH22G024425 1.8 FANTOM5 Ensembl ENCODE dbSUPER 13.9 +63.1 63117 13.9 HDGF PKNOX1 FOXA2 WRNIP1 SIN3A YY1 GLIS2 ZNF143 ZNF207 FOS POM121L9P UPB1 ADORA2A-AS1 SPECC1L BCRP3 GGTLC4P ADORA2A GGT1 PIR51261
GH22G024463 0.9 Ensembl ENCODE 26.6 +31.5 31533 1.1 NR2F1 HLF ARID4B ATF2 ZNF664 IKZF1 ZNF548 HNF4A ADORA2A-AS1 UPB1 ADORA2A SPECC1L ZNF70 SNRPD3 BCRP3 GC22P024440 GC22P024441
GH22G024548 2 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -58.4 -58388 8.9 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ENSG00000272973 UPB1 ADORA2A GGT1 ENSG00000228923 ADORA2A-AS1 SPECC1L POM121L9P BCRP3 GUCD1
GH22G024399 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +93.1 93147 4.7 HDGF PKNOX1 WRNIP1 SIN3A FEZF1 ZNF2 YY1 FOS ZNF263 JUNB POM121L9P SPECC1L UPB1 ENSG00000228923 ADORA2A-AS1 GGT1 LOC105372960 SPECC1L-ADORA2A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ADORA2A-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ADORA2A-AS1 Gene

Chromosome:
22
Start:
24,429,206 bp from pter
End:
24,495,074 bp from pter
Size:
65,869 bases
Orientation:
Minus strand

Genomic View for ADORA2A-AS1 Gene

Genes around ADORA2A-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADORA2A-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADORA2A-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADORA2A-AS1 Gene

Proteins for ADORA2A-AS1 Gene

  • Protein details for ADORA2A-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P86434-AAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein ADORA2A-AS1
    Protein Accession:
    P86434

    Protein attributes for ADORA2A-AS1 Gene

    Size:
    159 amino acids
    Molecular mass:
    17238 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This protein has no orthologs in other species and appears to be the product of a protein-coding gene which has arisen since divergence from chimp.

neXtProt entry for ADORA2A-AS1 Gene

Post-translational modifications for ADORA2A-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADORA2A-AS1 Gene

Domains & Families for ADORA2A-AS1 Gene

Protein Domains for ADORA2A-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADORA2A-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADORA2A-AS1 Gene

Function for ADORA2A-AS1 Gene

genes like me logo Genes that share phenotypes with ADORA2A-AS1: view

Animal Model Products

miRNA for ADORA2A-AS1 Gene

miRTarBase miRNAs that target ADORA2A-AS1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ADORA2A-AS1 Gene

Localization for ADORA2A-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADORA2A-AS1 Gene

Pathways & Interactions for ADORA2A-AS1 Gene

SuperPathways for ADORA2A-AS1 Gene

No Data Available

Interacting Proteins for ADORA2A-AS1 Gene

Gene Ontology (GO) - Biological Process for ADORA2A-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADORA2A-AS1 Gene

Drugs & Compounds for ADORA2A-AS1 Gene

(1) Drugs for ADORA2A-AS1 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methotrexate Approved Pharma Folate antagonist,inhibits DFHR 1551
genes like me logo Genes that share compounds with ADORA2A-AS1: view

Transcripts for ADORA2A-AS1 Gene

mRNA/cDNA for ADORA2A-AS1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ADORA2A-AS1 Gene

ADORA2A antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ADORA2A-AS1 Gene

No ASD Table

Relevant External Links for ADORA2A-AS1 Gene

GeneLoc Exon Structure for
ADORA2A-AS1
ECgene alternative splicing isoforms for
ADORA2A-AS1

Expression for ADORA2A-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADORA2A-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ADORA2A-AS1 Gene

This gene is overexpressed in Liver (x11.3), Testis (x6.5), and Brain - Putamen (basal ganglia) (x5.6).

SOURCE GeneReport for Unigene cluster for ADORA2A-AS1 Gene:

Hs.632761
genes like me logo Genes that share expression patterns with ADORA2A-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADORA2A-AS1 Gene

Orthologs for ADORA2A-AS1 Gene

Evolution for ADORA2A-AS1 Gene

ENSEMBL:
Gene Tree for ADORA2A-AS1 (if available)
TreeFam:
Gene Tree for ADORA2A-AS1 (if available)

No data available for Orthologs for ADORA2A-AS1 Gene

Paralogs for ADORA2A-AS1 Gene

No data available for Paralogs for ADORA2A-AS1 Gene

Variants for ADORA2A-AS1 Gene

Sequence variations from dbSNP and Humsavar for ADORA2A-AS1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs2298383 drug-response 24,429,543(+) CTCCC(A/C/T)GGGGC intron-variant, nc-transcript-variant
rs116629687 Uncertain significance 24,495,341(+) ACCTC(C/T)TCCCA nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs200677387 Uncertain significance 24,495,397(+) CGGAC(C/G/T)GTGGC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs541169952 Uncertain significance 24,495,393(+) CTGGC(A/G)GACCG nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs755104394 Uncertain significance 24,495,429(+) GTCGC(C/T)GGAGG nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ADORA2A-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv4528n100 CNV gain 25217958
dgv8039n54 CNV gain 21841781
esv2668824 CNV deletion 23128226
esv2678940 CNV deletion 23128226
esv2724041 CNV deletion 23290073
esv2724068 CNV deletion 23290073
esv3557989 CNV deletion 23714750
esv3568311 CNV loss 25503493
esv3575443 CNV gain 25503493
esv3647434 CNV loss 21293372
esv3647435 CNV loss 21293372
esv3893463 CNV gain 25118596
nsv1055830 CNV gain 25217958
nsv1057819 CNV gain 25217958
nsv1110863 OTHER inversion 24896259
nsv526567 CNV gain 19592680
nsv588744 CNV gain 21841781
nsv7350 OTHER inversion 18451855
nsv834160 CNV gain 17160897
nsv953062 CNV duplication 24416366
nsv9884 CNV gain+loss 18304495

Relevant External Links for ADORA2A-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADORA2A-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADORA2A-AS1 Gene

Disorders for ADORA2A-AS1 Gene

Relevant External Links for ADORA2A-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADORA2A-AS1

No disorders were found for ADORA2A-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADORA2A-AS1 Gene

Publications for ADORA2A-AS1 Gene

  1. Recent de novo origin of human protein-coding genes. (PMID: 19726446) Knowles D.G. … McLysaght A. (Genome Res. 2009) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ADORA2A-AS1 Gene

Sources for ADORA2A-AS1 Gene

Content
Loading form....