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ADORA2A Gene

protein-coding   GIFtS: 68

GC22P022997
adenosine A2a receptor
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ADORA2)
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
ADORA2 2, 3
RDC8 1, 2
hA2aR 2
Descriptions
adenosine A2 receptor 2
adenosine A2a receptor 2
adenosine receptor subtype A2a 2
External Ids
HGNC: 2631
Entrez Gene: 1352
UniProtKB: P292743
Ensembl: ENSG000001282717
Search outside databases for aliases for ADORA2A gene

Previous GC identifers: GC22P021519 GC22P023148 GC22P023153

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ADORA2A:
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity
of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins
which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and
platelets and it is a major target of caffeine. [provided by RefSeq]

UniProtKB/Swiss-Prot: AA2AR_HUMAN, P29274
Function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which
activate adenylyl cyclase

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADORA2A gene  

Entrez Gene cytogenetic band: 22q11.23   Ensembl cytogenetic band:  22q11.23   HGNC cytogenetic band: 22q11.23

ADORA2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P022997:     (about GC identifiers)

Start:
22,996,866 bp from pter
End:
23,168,325 bp from pter
Size:
171,460 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000022.9  NT_011520.11  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: AA2AR_HUMAN, P29274 (See protein sequence)
Recommended Name: Adenosine receptor A2a  
Size: 412 amino acids; 44707 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
PDB structures from and Proteopedia :
1MMH (3D)    1UPE (3D)    3EML (3D)    

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_000666.2  

    ENSEMBL proteins: 
    ENSP00000336630 ENSP00000351480 ENSP00000385337 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant ADORA2A Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Adenosine Receptor A2a)
    Human Recombinant Proteins from Abnova (ADORA2A)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624 membrane fraction TAS10051547
    GO:0005886 plasma membrane TAS8794889 10051547
    GO:0005887 integral to plasma membrane TAS8794889
    About this table

    Antibodies for ADORA2A: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of ADORA2A
    Sigma-Aldrich Antibodies for ADORA2A
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Adenosine Receptor A2a), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ADORA2A)
    Novus Biologicals Antibodies for ADORA2A

    Assays for ADORA2A: 
    Invitrogen Assays for ADORA2A
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    4 InterPro domains/families:
     IPR001634 Adenosn_rcpt
     IPR017452 GPCR_Rhodpsn_supfam
     IPR001513 Adeno_A2A_rcpt
     IPR000276 7TM_GPCR_Rhodpsn


       GeneDecks  ADORA2A for the domains selected above  
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    Graphical View of Domain Structure for InterPro Entry P29274

    ProtoNet protein and cluster: P29274

    2 Blocks protein families:
    IPB001513 Adenosine A2A receptor signature
    IPB001634 Adenosine receptor signature


    UniProtKB/Swiss-Prot: AA2AR_HUMAN, P29274
    Similarity: Belongs to the G-protein coupled receptor 1 family

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADORA2A)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADORA2A)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000675

                  Applied Biosystems Silencer® siRNAs for ADORA2A

                  Sigma-Aldrich siRNA and siRNA Panels for ADORA2A  
                         Sigma-Aldrich shRNA Panels and shRNA for ADORA2A  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ADORA2A
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000675
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000675
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_000675 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_000675

    UniProtKB/Swiss-Prot: AA2AR_HUMAN, P29274
    Function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which
    activate adenylyl cyclase

    Genatlas biochemistry entry for ADORA2A:
    adenosine receptor A2A,mainly expressed in the basal ganglia and immune tissues,G protein coupled
    receptor superfamily,activating adenylate cyclase

    8 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Adora2a):

    behavior/neurologicalgrowth/sizehematopoietic systemhomeostasis/metabolism
    immune systemnervous systemtouch/vibrissae

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001609 adenosine receptor activity, G-protein coupled IEA--
    GO:0004872 receptor activity IEA--
    GO:0004930 G-protein coupled receptor activity IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    2 Millipore Pathways for ADORA2A
     Development A2A receptor signaling
     Signal transduction IP3 signaling

       GeneDecks  ADORA2A for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  ADORA2A  (Your Favorite Gene powered by Ingenuity) 
     G-Protein Coupled Receptor Signaling
     cAMP-mediated Signaling

       GeneDecks  ADORA2A for the pathways selected above  
    About GeneDecksing

    3 Kegg Pathways  (Kegg details for ADORA2A):
     hsa04020 Calcium signaling pathway
     hsa04080 Neuroactive ligand-receptor interaction
     hsa04270 Vascular smooth muscle contraction

       GeneDecks  ADORA2A for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  ADORA2A 


    5/31 Interacting proteins for ADORA2A (ENSP000003514803 P292742) via UniProtKB, MINT, and/or STRING (see all 31 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADORA2AP292742MINT-6699346 MINT-6700472 MINT-6797129 MINT-6797142 MINT-6797156 MINT-6699330
    NAMPTP434902MINT-6538741
    ADAENSP000003619653STRING (score=.969)
    NTRK1ENSP000003514863STRING (score=.926)
    NTRK2ENSP000003653873STRING (score=.919)
    About this table

    5/15 Gene Ontology (GO) biological process terms (links to tree view) (see all 15 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006171 cAMP biosynthetic process TAS10899090
    GO:0006909 phagocytosis TAS8360491
    GO:0006915 apoptosis TAS7818494
    GO:0006954 inflammatory response TAS8360491
    GO:0006968 cellular defense response TAS10051547
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Sigma-Aldrich Small Molecules for ADORA2A:
    Mixed Agonist/Antagonist Antagonist Agonist Inhibitor Ligand

    Compounds for ADORA2A available from Tocris Bioscience
    CompoundAction CAS number
    SCH 442416Very selective, high affinity A2A antagonist[316173-57-6]
    SCH 58261Potent, highly selective A2A antagonist[160098-96-4]
    PSB 603Highly selective A2B antagonist
    ZM 241385Potent, highly selective A2A antagonist[139180-30-6]
    About this table


    10/51 Novoseek chemical compound relationships for ADORA2A gene (see all 51 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    cgs21680 89.39 5 8088373 (1), 17575165 (1), 9128830 (1), 18384819 (1)
    regadenoson 86.81 8 18561509 (2), 17679059 (2), 16555687 (1), 17112296 (1) (see all 7)
    istradefylline 85.47 5 14663020 (2), 15298067 (1), 17686497 (1), 15974638 (1)
    binodenoson 84.13 5 14734517 (3), 18561509 (1), 17531571 (1)
    8-(3-chlorostyryl)caffeine 84.12 9 8991804 (2), 8749024 (1), 8821736 (1), 8732271 (1)
    dpcpx 82.58 13 9806342 (2), 8028023 (1), 10513579 (1), 1694546 (1) (see all 9)
    4-(2-(7-amino-2-(2-furyl)(1,2,4)triazolo(2,3-a)(1,3,5)triazin-5-ylamino)ethyl)phenol 81.00 1 12909194 (1)
    kf 17837 80.29 7 8088373 (2), 8045270 (2), 8901821 (1)
    dmpx 80.20 16 9435909 (3), 10676861 (2), 10714888 (1), 10340308 (1) (see all 9)
    n6-cyclopentyladenosine 78.77 8 9806342 (1), 10676861 (1), 7930619 (1), 8808787 (1) (see all 6)
    About this table

    3 PharmGKB drug compound relationships for ADORA2A gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    caffeineFA  10728760 12106498
    methotrexateFA  12528125 10728760 12106498
    theophyllineFA  10728760
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADORA2A)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADORA2A)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000675

                  Sigma-Aldrich siRNA and siRNA Panels for ADORA2A  
                         Sigma-Aldrich shRNA Panels and shRNA for ADORA2A  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_000675  

    REFSEQ mRNAs for ADORA2A gene: 

    NM_000675.4   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_000675  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000675
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000675
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_000675 

    Additional cDNA sequence: 

    AK123058.1 AK289871.1 AK301420.1 AK312946.1 AY136747.1 BC013780.1 BT006999.1 CR456367.1 
    CR607919.1 CR611621.1 EU036687.1 EU036688.1 EU036689.1 EU036690.1 EU036691.1 EU036692.1 
    EU036693.1 EU036694.1 M97370.1 

    10 DOTS entries:

    DT.100661170  DT.120642587  DT.314671  DT.95310776  DT.120642847  DT.120642633  DT.100022626  DT.100780535 
    DT.97841065  DT.432224 

    24/83 AceView cDNA sequences (see all 83 ):

    CR607919 BU689218 BX432706 AK123058 BU738206 AY136747 BM556053 CR611621 
    AW245531 BP368389 CR456367 BX462613 AW274391 BM543787 BP366538 M97370 
    AW271618 AA429914 BG107240 CD367743 BG686029 BI224985 CK819042 CA307692 

    highest scoring ESTs for ADORA2A:

    AA761679 AA772974 AA831171 AA884414 AA905667 AA905668 AA974478 AA992777 AI000025 AI250766 

    Unigene Cluster for ADORA2A:

    Adenosine A2a receptor
    Hs.197029  [show with all ESTs]
    Unigene Representative Sequence: NM_000675


    GeneLoc Exon Structure

    3 Ensembl transcripts including schematic representations:
    ENST00000337539  ENST00000358654  ENST00000406084  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADORA2A expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADORA2A

    1 / 2 / 3

    4 probe-sets matching ADORA2A gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32114_s_at2, 3 U95-A 1 1.00 1.00 0.89 0.93 S46950 0.80 0.88 0.84 1

    32115_r_at2, 3 U95-A 1 1.00 1.00 0.77 1.07 X68486 0.60 0.62 0.61 1

    205013_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_000675 0.60 0.83 0.73 1

    205013_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ADORA2A for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TGCTGAGTAG

    SOURCE GeneReport for Unigene cluster: Hs.197029

    Expression variation in blood from EXPOLDB for ADORA2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ADORA2A gene from 5/10 species (see all 10 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ADORA2A1   -- adenosine A2a receptor 91.02(n)
    93.2(a)
    403960  NM_001003278.1  NP_001003278.1 
    chimpanzee
    (Pan troglodytes)
    ADORA2A1   -- adenosine A2a receptor 99.51(n)
    99.76(a)
    458714  XM_515035.2  XP_515035.2 
    cow
    (Bos taurus)
    ADORA2A1   -- adenosine A2a receptor 84.69(n)
    84.01(a)
    617828  XM_870153.2  XP_875246.2 
    rat
    (Rattus norvegicus)
    Adora2a1   -- adenosine A2a receptor 83.62(n)
    84.29(a)
    25369  NM_053294.3  NP_445746.3 
    mouse
    (Mus musculus)
    Adora2a1, 5 105
    adenosine A2a receptor1, 5 84.37(n)1
    84.79(a)1
    115401  NM_009630.21  NP_033760.21 
     AK0377875  AK2066185  (see all 16)
    About this table        Species with no ortholog for ADORA2A

    ENSEMBL Gene Tree for ADORA2A
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADORA2A gene
    GPR1192  ADORA2B2  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/93 NCBI SNPs in ADORA2A are shown (see all 93 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 63)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 22 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs124841151,2
    C,F,H23152446(+) GAAGGG/ATCTGG 1 -- ng514Minor allele frequency- A:0.00EU EA WA 418
    rs45301,2
    C,F,H23159521(+) GGCGGC/TGGCCG 1 A/V mis1 ese315Minor allele frequency- T:0.01MN NA EU EA WA 1496
    rs72850571,2
    F,H23152663(+) CTCCAT/CGGATC 1 -- ng514Minor allele frequency- C:0.07EU EA WA 408
    rs49901,2
    C,H23167117(+) CTTCCG/ACAAGA 1 H/R mis1 ese37Minor allele frequency- A:0.01MN EU EA WA 842
    rs57604131,2
    C,H23153325(+) TTGCAG/ACCACC 1 -- ng515Minor allele frequency- A:0.00EU EA WA 598
    rs49921,2
    H23167752(+) ATCTGG/TAAGCA 1 -- ut316Minor allele frequency- T:0.01MN EU EA WA 670
    rs176509371,2
    C,F,H23167103(+) GAGTTC/TCGCCA 1 F/F syn17Minor allele frequency- T:0.00NA EU EA WA 562
    rs49911,2
    C,F,H23167262(+) GCCAAC/TGGCAG 1 N/N syn1 ese39Minor allele frequency- T:0.02MN NA EU EA WA 806
    rs81924461,2
    C,F,H23166650(+) TGGAAC/TAACTG 1 N/N syn17Minor allele frequency- T:0.00EU EA WA NA 552
    --
    rs57518761,2
    A,C23167301(+) GGCTAC/TGCCCT 1 Y/Y syn10--------
    About this table

    HapMap Linkage Disequilibrium images for ADORA2A (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 102776

    10/30 Novoseek disease relationships for ADORA2A gene (see all 30 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    parkinson disease 63.39 35 15033896 (4), 15719154 (2), 9345853 (2), 16022182 (2) (see all 26)
    basal ganglia disorders 56.68 1 18221214 (1)
    huntington disease 51.36 6 18536175 (1), 16184606 (1), 15689617 (1), 17303312 (1) (see all 6)
    neurodegenerative diseases 39.71 3 8991804 (1), 12958155 (1), 18536175 (1)
    catalepsy 33.41 3 9128830 (2)
    neurodegeneration 32.42 1 14720203 (1)
    pheochromocytoma 16.12 3 10400659 (1), 12590138 (1), 9920286 (1)
    schizophrenia 12.23 5 9029412 (2), 15719154 (2)
    goiter 10.93 2 12740015 (1)
    panic disorder 9.94 4 15774265 (2), 9491818 (1), 11515749 (1)
    About this table

    1 PharmGKB disease relationship for ADORA2A gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Arthritis, ExperimentalFA  10728760
    About this table

    Human Gene Mutation Database: ADORA2A
    Genetic Association Database: ADORA2A
    Human Genome Epidemiology Navigator: ADORA2A (18 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/371 PubMed articles for ADORA2A gene (see all 371 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 135 HGNC: 263 AceView: ADORA2A Ensembl:ENSG00000128271 euGenes: HUgn135
    ECgene: ADORA2A H-InvDB: ADORA2A
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADORA2A:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADORA2A-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADORA2A Antibodies for ADORA2A
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADORA2A Small molecules for ADORA2A
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant & Natural Proteins  

     Recombinant Proteins (ADORA2A)
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     Antibodies for ADORA2A

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