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ADO Gene

protein-coding   GIFtS: 54
GCID: GC10P064564

2-Aminoethanethiol (Cysteamine) Dioxygenase

(Previous name: chromosome 10 open reading frame 22)
(Previous symbol: C10orf22)
  Search for ADO
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
2-Aminoethanethiol (Cysteamine) Dioxygenase1 2     2-Aminoethanethiol Dioxygenase2
C10orf221 2 3 5     Cysteamine (2-Aminoethanethiol) Dioxygenase (ADO)2
Cysteamine Dioxygenase1 2 3     EC 1.13.11.193
Chromosome 10 Open Reading Frame 221     

External Ids:    HGNC: 235061   Entrez Gene: 848902   Ensembl: ENSG000001819157   OMIM: 6113925   UniProtKB: Q96SZ53   

Export aliases for ADO gene to outside databases

Previous GC identifers: GC10P064235 GC10P058556


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ADO Gene:
Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol)
dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to
free cysteamine to form hypotaurine (Dominy et al., 2007 (PubMed 17581819)).(supplied by OMIM, Mar 2008)

GeneCards Summary for ADO Gene:
ADO (2-aminoethanethiol (cysteamine) dioxygenase) is a protein-coding gene. GO annotations related to this gene include cysteamine dioxygenase activity.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the ADO gene promoter:
         Tal-1   NF-kappaB   HNF-1A   E47   Gfi-1   CREB   deltaCREB   HNF-1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADO promoter sequence
   Search Chromatin IP Primers for ADO

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADO


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.3   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q21.3

ADO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADO gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P064564:  view genomic region     (about GC identifiers)

Start:
64,564,516 bp from pter      End:
64,568,239 bp from pter
Size:
3,724 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: AEDO_HUMAN, Q96SZ5 (See protein sequence)
Recommended Name: 2-aminoethanethiol dioxygenase  
Size: 270 amino acids; 29751 Da
Cofactor: Iron (By similarity)
Sequence caution: Sequence=BAB55123.1; Type=Erroneous initiation;
Secondary accessions: B1AL29

Explore the universe of human proteins at neXtProt for ADO: NX_Q96SZ5

Explore proteomics data for ADO at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys55
  • Modification sites at PhosphoSitePlus

  • See ADO Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116193.2  
    ENSEMBL proteins: 
     ENSP00000362888  

    ADO Human Recombinant Protein Products:

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    Novus Biologicals ADO Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ADO

     
    Search eBioscience for Proteins for ADO 

    ADO Antibody Products:

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    ThermoFisher Antibodies for ADO
    LSBio Antibodies in human, mouse, rat for ADO

    ADO Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ADO
    Cloud-Clone Corp. CLIAs for ADO
    Search eBioscience for ELISAs for ADO 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011051 RmlC_Cupin
     IPR012864 Cysteamine_dioxygenase
     IPR014710 RmlC-like_jellyroll

    Graphical View of Domain Structure for InterPro Entry Q96SZ5

    ProtoNet protein and cluster: Q96SZ5

    1 Blocks protein domain: IPB012864 Protein of unknown function DUF1637


    Find genes that share domains with ADO           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AEDO_HUMAN, Q96SZ5
    Catalytic activity: 2-aminoethanethiol + O(2) = hypotaurine

         Enzyme Number (IUBMB): EC 1.13.11.191

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
    GO:0047800cysteamine dioxygenase activity IEA--
         
    Find genes that share ontologies with ADO           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADO
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ADO

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ADO
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ADO

    miRNA
    Products:
        
    miRTarBase miRNAs that target ADO:
    hsa-mir-101-3p (MIRT027340), hsa-mir-7-5p (MIRT025852), hsa-mir-128-3p (MIRT022087), hsa-mir-29c-3p (MIRT020373), hsa-mir-122-5p (MIRT023381), hsa-mir-34a-5p (MIRT025531), hsa-mir-99a-5p (MIRT048683)

    Block miRNA regulation of human, mouse, rat ADO using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ADO (see all 62):
    hsa-miR-25 hsa-miR-30d hsa-miR-218 hsa-miR-449a hsa-miR-30a hsa-miR-2116 hsa-miR-3909 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidADO 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ADO
    Predesigned siRNA for gene silencing in human, mouse, rat ADO

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ADO

    Clone
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    OriGene clones in human, mouse for ADO (see all 6)
    OriGene ORF clones in mouse, rat for ADO
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    GenScript: all cDNA clones in your preferred vector (see all 2): ADO (NM_000674)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADO
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADO

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ADO 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADO


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    extracellular2
    mitochondrion2
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with ADO           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ADO About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.38
    2Taurine and hypotaurine metabolism
    Taurine and hypotaurine metabolism0.31


    Find genes that share SuperPaths with ADO           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for ADO):
        Taurine and hypotaurine metabolism
    Metabolic pathways

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ADO
    Interactions:

        Search GeneGlobe Interaction Network for ADO

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ADO (ENSP000003628884) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSADENSP000002670854STRING: ENSP00000267085
    GAD1ENSP000003509284STRING: ENSP00000350928
    GAD2ENSP000002592714STRING: ENSP00000259271
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with ADO           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ADO (AEDO)

    4 HMDB Compounds for ADO    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cysteamine(2-Mercaptoethyl)amine (see all 30)60-23-1--
    Hypotaurine2-Aminoethylsulfinate (see all 9)300-84-5--
    IronArmco iron (see all 19)7439-89-6--
    OxygenOxygen (see all 5)7782-44-7--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ADO gene: 
    NM_032804.5  

    Unigene Cluster for ADO:

    2-aminoethanethiol (cysteamine) dioxygenase
    Hs.99821  [show with all ESTs]
    Unigene Representative Sequence: NM_032804
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000373783(uc001jmg.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ADO using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ADO (see all 62):
    hsa-miR-25 hsa-miR-30d hsa-miR-218 hsa-miR-449a hsa-miR-30a hsa-miR-2116 hsa-miR-3909 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidADO 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ADO
    Predesigned siRNA for gene silencing in human, mouse, rat ADO
    Clone
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    OriGene clones in human, mouse for ADO (see all 6)
    OriGene ORF clones in mouse, rat for ADO
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ADO (NM_000674)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADO
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADO
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ADO
    OriGene qSTAR qPCR primer pairs in human, mouse for ADO
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADO
      QuantiTect SYBR Green Assays in human, mouse, rat ADO
      QuantiFast Probe-based Assays in human, mouse, rat ADO

    Additional mRNA sequence: 

    AK027453.1 AK127694.1 AL049319.1 BC018660.1 BC028589.2 BC067740.1 

    3 DOTS entries:

    DT.217168  DT.95171469  DT.91658239 

    Selected AceView cDNA sequences (see all 173):

    BM806539 AW629650 BQ022240 AA361164 AI359042 AK027453 BF036875 CR611168 
    BM682343 NM_032804 BU164906 BC028589 BC067740 AI538170 AW161420 AI469832 
    BU621225 AA489643 AA593104 BX118729 BE895944 BM717809 AI805066 BM560997 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ADO expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCACTGTT
    ADO Expression
    About this image


    ADO expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Spinal Cord (Nervous System)
    ADO Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ADO Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.99821
        Custom PCR Arrays for ADO
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat ADO
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADO

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ADO gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ado1 , 5 2-aminoethanethiol (cysteamine) dioxygenase1, 5 87.5(n)1
    89.45(a)1
      10 (34.96 cM)5
    2114881  NM_001005419.21  NP_001005419.21 
     675445125 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ado1 2-aminoethanethiol (cysteamine) dioxygenase 65.59(n)
    59.27(a)
      100485786  XM_002939541.2  XP_002939587.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BM534156.12   -- 80.59(n)   325039  BM534156.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG75501 CG7550 47.72(n)
    36.04(a)
      38901  NM_139919.2  NP_648176.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y50D4C.66
    Protein Y50D4C.6 (Y50D4C.6) mRNA, complete cds
    25(a)
    1 ↔ 1
    V(946731-949860) WBGene00021750


    ENSEMBL Gene Tree for ADO (if available)
    TreeFam Gene Tree for ADO (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ADO (see all 125)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs79056541,2
    C,A--64562524(+) tcccaG/Acactt 1 -- us2k13Minor allele frequency- A:0.20NA CSA 5
    rs1891713741,2
    C--64562542(+) CCGAGC/GGGGGC 1 -- us2k10--------
    rs79220821,2
    C,A--64562588(+) taacaC/Tggtga 1 -- us2k12Minor allele frequency- T:0.00WA CSA 3
    rs1809028591,2
    --64562601(+) CCCCGG/TCTCTA 1 -- us2k10--------
    rs1855514591,2
    --64562614(+) AAATAC/TACAGA 1 -- us2k10--------
    rs1903154251,2
    --64562649(+) GCGGGA/CATCTG 1 -- us2k10--------
    rs1120190191,2
    C,F--64562773(+) CTCCGC/TCTCAA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1178275901,2
    C--64562785(+) AAAAAA/TAATAA 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1413548081,2
    C--64562913(+) CCTCA-/AAAC  
            
    AAACA
    1 -- us2k10--------
    rs2001534581,2
    --64562931(+) AACAA-/ACAAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ADO (64564516 - 64568239 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ADO:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv895570CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ADO
    DNA2.0 Custom Variant and Variant Library Synthesis for ADO

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611392    OMIM disorders: --

    3 diseases from the University of Copenhagen DISEASES database for ADO:
    Patent ductus arteriosus     Osteopetrosis     Vascular disease

    Find genes that share disorders with ADO           About GenesLikeMe

    Genetic Association Database (GAD): ADO
    Human Genome Epidemiology (HuGE) Navigator: ADO (4 documents)

    Export disorders for ADO gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ADO gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ADO)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase. (PubMed id 17581819)1, 2, 3 Dominy J.E. Jr.... Stipanuk M.H. (J. Biol. Chem. 2007)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. (PubMed id 22327514)1 Postel-Vinay S....Delattre O. (Nat. Genet. 2012)
    6. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1 Kenny E.E....Peter I. (PLoS Genet. 2012)
    7. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. (PubMed id 23042114)1 Hirota T....Tamari M. (Nat. Genet. 2012)
    8. Genetic variants associated with breast size also influence breast cancer risk. (PubMed id 22747683)1 Eriksson N....Tung J.Y. (BMC Med. Genet. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84890 HGNC: 23506 AceView: C10orf22 Ensembl:ENSG00000181915 euGenes: HUgn84890
    ECgene: ADO Kegg: 84890 H-InvDB: ADO

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ADO Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=C10orf2[genesymbol]

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ADO gene:
    Search GeneIP for patents involving ADO

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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