ADIPOR2 Gene
protein-coding GIFtS: 57
GCID: GC12P001801
|
|
adiponectin receptor 2
| |
Aliases
for ADIPOR2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adiponectin Receptor 21 2 | | PAQR21 2 3 | | ACDCR21 2 | | Progestin And AdipoQ Receptor Family Member II2 3 | | Adiponectin Receptor Protein 22 |
Export aliases for ADIPOR2 gene to outside databasesPrevious GC identifers: GC12P001679 GC12P001670 |
Summaries
for ADIPOR2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ADIPOR2:
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-lengthadiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligandactivities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 (PubMed12802337)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24Function: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes thatacts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acidoxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Hassome intermediate-affinity receptor activity for both globular and full-length adiponectin
|
Genomic Views
for ADIPOR2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009759.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ADIPOR2 gene promoter:
TBP GR LHX3b/Lhx3b AP-1 ATF-2 PPAR-gamma1 LHX3a/Lhx3a c-Jun GR-alpha PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ADIPOR2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADIPOR2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p13.31 Ensembl cytogenetic band: 12p13.33 HGNC cytogenetic band: 12p13ADIPOR2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P001801: view genomic region
(about GC identifiers)
Start:
|
1,797,740 bp from pter |
End:
|
1,897,845 bp from pter |
Size:
|
100,106 bases |
Orientation:
|
plus strand |
|
Proteins
for ADIPOR2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24 (See
protein sequence)Recommended Name: Adiponectin receptor protein 2 Size: 386 amino acids; 43884 Da
Subunit: May form homomultimer and heteromultimers
Subcellular location: Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellularorganelles
Sequence caution: Sequence=BAB15062.1; Type=Erroneous initiation;
Secondary accessions: Q53YY5 Q9H737Explore the universe of human proteins at neXtProt for ADIPOR2: NX_Q86V24
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86V24
ADIPOR2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_078827.2
ENSEMBL proteins: ENSP00000349616
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
ADIPOR2 for ontologies About GeneDecksing
ADIPOR2 Antibody Products:
Assay Products for ADIPOR2: |
Protein
Domains /
Families
for ADIPOR2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ADIPOR2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86V24ProtoNet protein and cluster: Q86V24 1 Blocks protein family: IPB004254 Hly-III related proteins
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24Domain: The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellularSimilarity: Belongs to the ADIPOR family |
Function
for ADIPOR2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24Function: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes thatacts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acidoxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Hassome intermediate-affinity receptor activity for both globular and full-length adiponectin
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ADIPOR2 (NM_024551) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADIPOR2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADIPOR2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADIPOR2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ADIPOR2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Adipor2tm1Tka for ADIPOR2
8 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Adipor2):
ADIPOR2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ADIPOR2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | AMPK signaling | | | 2 | Development_Leptin signaling via PI3K-dependent pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for ADIPOR2
1 
Kegg Pathway (Kegg details for ADIPOR2):
ADIPOR2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADIPOR2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/16 Interacting proteins for ADIPOR2 (Q86V241, 3 ENSP000003496164) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ADIPOR2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ADIPOR2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ADIPOR2 for compounds About GeneDecksing
 Browse Tocris compounds for ADIPOR2
8 Novoseek chemical compound relationships for ADIPOR2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| pioglitazone |
56.2 |
3 |
17950097 (1), 19169664 (1) |
| glucose |
53.9 |
19 |
17068142 (2), 17878241 (2), 15855268 (1), 18294218 (1) (see all 12) |
| fatty acid |
41.2 |
4 |
20032495 (1), 16055297 (1), 15769985 (1), 19636528 (1) |
| lipid |
36.4 |
7 |
17878241 (2), 17068142 (1), 19502591 (1), 16205883 (1) (see all 5) |
| rosiglitazone |
33.1 |
2 |
15824748 (1), 15991021 (1) |
| palmitate |
32.8 |
5 |
19502591 (2), 19636528 (1), 20470935 (1) |
| p003 |
6.53 |
1 |
15105989 (1) |
| testosterone |
0 |
1 |
16899222 (1) |
Search CenterWatch for drugs/clinical trials and news about ADIPOR2 / ADR2
|
Transcripts
for ADIPOR2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ADIPOR2 gene: NM_024551.2 Unigene Cluster for ADIPOR2: Adiponectin receptor 2 Hs.371642 [show with all ESTs]Unigene Representative Sequence: AK1285117 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000537545 ENST00000357103(uc001qjm.3 uc001qjn.3) ENST00000540974
ENST00000543456 ENST00000535774 ENST00000544470 ENST00000537190
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ADIPOR2 (NM_024551) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADIPOR2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADIPOR2 |
Additional cDNA sequence: AK025085.1 AK127111.1 AK127196.1 AK128511.1 AY424280.1 BC004906.2 BC051858.2 16 DOTS entries: DT.445383 DT.121137533 DT.101984550 DT.92450046 DT.95157752 DT.101976438 DT.121137551 DT.100657431 DT.91886273 DT.92450041 DT.121137543 DT.121137614 DT.121137628 DT.40313712 DT.95157758 DT.99995379 24/430 AceView cDNA sequences (see all 430): BM771522 BM921518 BM876351 AA251662 AI191930 BF197223 BP381353 BF589059 BM471245 BQ005956 CB160653 BE268028 BU539201 BU188378 AA374731 AI270434 BE312641 CR591974 AI610883 AW631090 BE205856 AK127196 AW296756 BU186518
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ADIPOR2 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 |
|---|
|
| SP1: | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ADIPOR2
|
Expression
for ADIPOR2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ADIPOR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCACTTGAC
About this image
See ADIPOR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ADIPOR2
SOURCE GeneReport for Unigene cluster: Hs.371642
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24Tissue specificity: Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon,spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung
SABiosciences Expression via Pathway-Focused PCR Arrays including ADIPOR2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADIPOR2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ADIPOR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADIPOR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADIPOR2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADIPOR2 |
Orthologs
for ADIPOR2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ADIPOR2 gene from 9/32 species (see all 32) About this table
ENSEMBL Gene Tree for ADIPOR2 (if available)
TreeFam Gene Tree for ADIPOR2 (if available) |
Paralogs
for ADIPOR2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ADIPOR2 gene
- ADIPOR12 PAQR92 PAQR32 PAQR82 PAQR72 PAQR42 PAQR62 PAQR52
2 SIMAP similar genes for ADIPOR2 using alignment to 1 protein entry: ADR2_HUMAN:ADIPOR1 PAQR3
ADIPOR2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ADIPOR2
PGOHUM00000238696
|
Genomic Variants
for ADIPOR2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ADIPOR2 (1797740 - 1897845 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ADIPOR2
2 CNVs: 4765 101404
4 Indels: 24961 39872 43116 11592 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADIPOR2 |
|
Disorders
/ Diseases
for ADIPOR2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ADIPOR2 for disorders About GeneDecksing
OMIM gene information: 607946
OMIM disorders: --
20/31  diseases for ADIPOR2 (see all 31): About MalaCardsanorexia nervosa nonalcoholic steatohepatitis gastrointestinal stromal tumor polycystic ovary syndrome
insulin resistance fatty liver disease morbid obesity liver disease
ileus liver cirrhosis rheumatoid arthritis hepatitis c
obesity chondrosarcoma breast cancer twinning
colon cancer arthritis osteoarthritis gastric cancer
2 diseases from the University of Copenhagen DISEASES database for ADIPOR2:Diabetes mellitus Fatty liver disease 10/16 Novoseek disease relationships for ADIPOR2 gene (see all 16) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| insulin sensitivity |
75 |
12 |
19037660 (4), 14759511 (1), 16551730 (1), 19169664 (1) (see all 8) |
| insulin resistance |
72.5 |
29 |
15918014 (4), 17216283 (3), 14759511 (2), 17716299 (2) (see all 17) |
| obesity |
61.2 |
13 |
16756736 (2), 17878241 (2), 17607322 (2), 16493120 (1) (see all 10) |
| fatty liver |
48.2 |
1 |
17006986 (1) |
| impaired glucose tolerance |
43.2 |
2 |
17391161 (1), 17878241 (1) |
| liver diseases |
28.1 |
1 |
17006986 (1) |
| dyslipidemia |
15.2 |
2 |
17068142 (1), 16700915 (1) |
| inflammation |
15.2 |
2 |
19136982 (1), 16700915 (1) |
| cardiovascular diseases |
14.8 |
1 |
16756736 (1) |
| anorexia nervosa |
12 |
1 |
17391161 (1) |
Genetic Association Database (GAD): ADIPOR2
Human Genome Epidemiology (HuGE) Navigator: ADIPOR2 (37 documents)
Export disorders for ADIPOR2 gene to outside databases
|
Publications
for ADIPOR2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ADIPOR2 gene, integrated from 9 sources (see all 182):
(articles sorted by number of sources associating them with ADIPOR2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. (PubMed id 12802337)1, 2, 3 Yamauchi T.... Kadowaki T. (2003)
- Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. (PubMed id 15918014)1, 4, 9 Hara K....Kadowaki T. (2005)
- Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. (PubMed id 15983228)1, 4, 9 Damcott C.M....Shuldiner A.R. (2005)
- Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. (PubMed id 16205883)1, 4, 9 Stefan N....Haring H.U. (2005)
- PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. (PubMed id 16044242)1, 2 Tang Y.T....Funk W.D. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genetic variation in the adiponectin receptor 2 (ADIP OR2) gene is associated with coronary artery disease and increased ADIPOR2 expression in peripheral monocytes. (PubMed id 20178558)1, 9 Halvatsiotis I....Raptis S.A. (2010)
- AdipoR2 is transcriptionally regulated by ER stress-i nducible ATF3 in HepG2 human hepatocyte cells. (PubMed id 20423458)1, 9 Koh I.U....Song J. (2010)
- Low-abundant adiponectin receptors in visceral adipos e tissue of humans and rats are further reduced in diabetic animals. (PubMed id 20470935)1, 9 Bauer S....Buechler C. (2010)
|
External Searches for ADIPOR2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ADIPOR2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ADIPOR2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ADIPOR2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ADIPOR2 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Adiponectin |
|
| | |
About This Section
| Patent Information for ADIPOR2 gene:
Search GeneIP for patents involving ADIPOR2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ADIPOR2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ADIPOR2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADIPOR2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADIPOR2 | | | OriGene Protein Over-expression Lysate for ADIPOR2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ADIPOR2 | | OriGene 3'-UTR Clone for ADIPOR2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADIPOR2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ADIPOR2 | | OriGene Custom Protein Services for ADIPOR2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADIPOR2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADIPOR2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADIPOR2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADIPOR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADIPOR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADIPOR2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ADIPOR2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ADIPOR2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADIPOR2 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADIPOR2 |
|
|
|
|
