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ADIPOR2 Gene

protein-coding GIFtS: 54

GC12P001670

adiponectin receptor 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
ACDCR2 ^¹, ²
FLJ21432 ^²
MGC4640 ^²
OTTHUMP00000160634 ^²
PAQR2 ^¹, ², ³

Descriptions
Progestin and adipoQ receptor family member II ^³
adiponectin receptor 2 ^²

External Ids
HGNC: 24041¹
Entrez Gene: 79602²
UniProtKB: Q86V24³
Ensembl: ENSG00000006831⁷

Search outside databases for aliases for ADIPOR2 gene

Previous GC identifer: GC12P001679

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ADIPOR2:

The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and

full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha

(PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by

adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM]

UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24

Function: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted

by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate

lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity,

fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor

activity for both globular and full-length adiponectin

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ADIPOR2 gene

Entrez Gene cytogenetic band: 12p13.31 Ensembl cytogenetic band: 12p13.33 HGNC cytogenetic band: 12p13

ADIPOR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P001670: (about GC identifiers)

Start:	1,670,508 bp from pter
End:	1,768,106 bp from pter
Size:	97,599 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_009759.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24 (See protein sequence)

Recommended Name: Adiponectin receptor protein 2

Size: 386 amino acids; 43884 Da

Subunit: May form homo and heteromultimers

Subcellular location: Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane

and intracellular organelles

Secondary accessions: Q9H737

REFSEQ proteins: NP_078827.2

ENSEMBL proteins:

ENSP00000349616

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Adiponectin Receptor 2)
	Human Recombinant Proteins from Abnova (ADIPOR2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for ADIPOR2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Adiponectin Receptor 2), each with their Abpromise^SM
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	Search Novus for antibodies for ADIPOR2

Assays for ADIPOR2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q86V24

ProtoNet protein and cluster: Q86V24

1 Blocks protein family: IPB004254 Hly-III related proteins

UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24

Similarity: Belongs to the ADIPOR family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADIPOR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADIPOR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_024551

Applied Biosystems Silencer® siRNAs for ADIPOR2

Sigma-Aldrich siRNA and siRNA Panels for ADIPOR2

Sigma-Aldrich shRNA for ADIPOR2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ADIPOR2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_024551
Myc/DDK tagged cDNA clone in CMV expression vector: NM_024551
untagged cDNA clone in CMV expression vector: NM_024551

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_024551

UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24

Function: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted

by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate

lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity,

fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor

activity for both globular and full-length adiponectin

8 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Adipor2):

adipose tissue	behavior/neurological	digestive/alimentary	endocrine/exocrine gland	growth/size
homeostasis/metabolism	nervous system	reproductive system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	IEA	--
GO:0042562	hormone binding	ISS	12802337
GO:0042802	identical protein binding	IEA	--
GO:0046982	protein heterodimerization activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for ADIPOR2 (Your Favorite Gene powered by Ingenuity)

PPAR&alpha
Type II Diabetes Mellitus Signaling

GeneDecks ADIPOR2 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for ADIPOR2

5/11 Interacting proteins for ADIPOR2 (Q86V24¹ ENSP00000349616³) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
APPL1	Q9UKG1¹, ENSP00000288266³	EBI-1769445, EBI-741243 STRING (score=.927)
ADIPOQ	ENSP00000320709³	STRING (score=.998)
PPARA	ENSP00000262735³	STRING (score=.979)
INS	ENSP00000370731³	STRING (score=.968)
PPARG	ENSP00000287820³	STRING (score=.914)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006629	lipid metabolic process	IEA	--
GO:0007565	female pregnancy	IEA	--
GO:0007584	response to nutrient	IEA	--
GO:0009755	hormone-mediated signaling	ISS	12802337
GO:0019395	fatty acid oxidation	ISS	12802337

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ADIPOR2
4 Novoseek chemical compound relationships for ADIPOR2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glucose	53.52	17	17068142 (2), 17878241 (2), 15855268 (1), 18294218 (1) (see all 10)
fatty acid	40.07	2	16055297 (1), 15769985 (1)
lipid	33.86	5	17878241 (2), 17068142 (1), 16205883 (1), 16756736 (1)
p003	11.60	1	15105989 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADIPOR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADIPOR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_024551

Sigma-Aldrich siRNA and siRNA Panels for ADIPOR2

Sigma-Aldrich shRNA for ADIPOR2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_024551

REFSEQ mRNAs for ADIPOR2 gene:

NM_024551.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_024551

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_024551
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_024551
                                 untagged cDNA clone in CMV expression vector: NM_024551

Additional cDNA sequence:

AK025085.1 AK127111.1 AK127196.1 AK128511.1 AY424280.1 BC004906.2 BC051858.2 CR610048.1

CR613880.1

16 DOTS entries:

DT.445383 DT.121137533 DT.101984550 DT.101976438 DT.92450046 DT.95157752 DT.100657431 DT.121137551

DT.91886273 DT.92450041 DT.121137543 DT.121137614 DT.121137628 DT.40313712 DT.95157758 DT.99995379

24/430 AceView cDNA sequences (see all 430 ):

BP430930 BU943971 AI191930 CA390994 BI859881 CB160653 AI339454 BP381353

BU539201 BQ431377 BQ431429 AI829022 BU539616 BU629483 AA480644 BF589059

BU736841 BQ279076 AW778845 CR591974 BM666372 AA588196 AA379254 AI205733

highest scoring ESTs for ADIPOR2:

AA903403 AA045263 AA045271 AA055331 AA055928 AA121694 AA121748 AA126324 AA130635 AA130738

Unigene Cluster for ADIPOR2:

Adiponectin receptor 2

Hs.371642 [show with all ESTs]

Unigene Representative Sequence: AK128511

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for ADIPOR2

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8
SP1:					-										-		-
SP2:															-		-
SP3:
SP4:

About this scheme

ECgene alternative splicing isoforms for ADIPOR2

1 Ensembl transcript including schematic representation:

ENST00000357103

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ADIPOR2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ADIPOR2

¹ / ² / ³

4 probe-sets matching ADIPOR2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39045_at²^{, 3}	U95-A	1	1.00	1.00	0.95	1.07	W26655	0.80	1.00	0.91	1
82083_at²^{, 3}	U95-E	1	1.00	1.00	0.87	0.93	AA903403	1.00	1.00	1.00	1
201346_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_024551	0.60	1.00	0.82	1
201346_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.371642
Expression variation in blood from EXPOLDB for ADIPOR2
UniProtKB/Swiss-Prot: ADR2_HUMAN, Q86V24
Tissue specificity: Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in
brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ADIPOR2 gene from 5/16 species (see all 16 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ADIPOR2¹	--	adiponectin receptor 2	92.66(n) 96.37(a)	477732 XM_534929.2 XP_534929.2
chimpanzee (Pan troglodytes)	ADIPOR2¹	--	adiponectin receptor 2	99.57(n) 100(a)	451742 XM_508922.2 XP_508922.2
cow (Bos taurus)	ADIPOR2¹	--	adiponectin receptor 2	86.87(n) 92.23(a)	407234 NM_001040499.1 NP_001035589.1
rat (Rattus norvegicus)	Adipor2¹	--	adiponectin receptor 2	89.72(n) 93.26(a)	312670 NM_001037979.1 NP_001033068.1
mouse (Mus musculus)	Adipor2^{1, 5}	6 (60.70 cM)⁵	adiponectin receptor 2^{1, 5}	89.64(n)¹ 92.75(a)¹	68465¹ NM_197985.3¹ NP_932102.2¹ AI115388⁵ AI854179⁵ (see all 21)

About this table Species with no ortholog for ADIPOR2

ENSEMBL Gene Tree for ADIPOR2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for ADIPOR2 gene

ADIPOR1² PAQR4² PAQR3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/545 NCBI SNPs in ADIPOR2 are shown (see all 545 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 178)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1029629^1,2	A,C,F,H,O	1669528(-)	`TCCTTA/CCCTTT`	1	--	ng5¹		5		MN EU EA WA	602
	rs1044471^1,2	A,C,F,H	1767217(+)	`CCTCCC/TTTGCC`	1	--	ut3¹ ese³ trp³		12		EA MN EU WA	3766
	rs12342^1,2	A,C,F,H	1767141(-)	`AGGACG/ACCAGT`	1	--	ut3¹ ese³		11		MN EA EU WA	3720
	rs2286380^1,2	A,C,F,H	1767545(-)	`TGTTGT/AGACAG`	1	--	ut3¹ ese³		9		EA EU WA	2318
	rs2286382^1,2	C,F,H	1767040(-)	`AGACTC/TGAGCA`	1	--	ut3¹ ese³		13		EA MN EU WA	3746
	rs12298275^1,2	C,F,H	1733886(+)	`CCACCA/GAGGAG`	1	Q/R	mis¹ ese³		8		EU EA WA	840
--	rs730032^1,2	A,C,F	1765633(-)	`AGCCAC/TTGGGC`	1	--	ut3¹ ese³		2		MN EA	1678
	rs10773980^1,2	A,C	1668979(+)	`TTTTTC/TGCTCT`	1	--	ng5¹		0	--	--	--	--
--	rs758169^1,2	A,C	1765634(-)	`GAGCCC/ACTGGG`	1	--	ut3¹ ese³		1		MN	184
--	rs7970795^1,2	A,H	1668577(+)	`CCCTTC/TGTTTT`	1	--	ng5¹		2		EU WA	240

About this table

HapMap Linkage Disequilibrium images for ADIPOR2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 607946

10/13 Novoseek disease relationships for ADIPOR2 gene (see all 13 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
insulin sensitivity	74.72	12	19037660 (4), 14759511 (1), 16551730 (1), 19169664 (1) (see all 8)
insulin resistance	71.44	26	15918014 (4), 17216283 (3), 14759511 (2), 17878241 (2) (see all 15)
obesity	61.98	12	16756736 (2), 17878241 (2), 17607322 (2), 16493120 (1) (see all 9)
impaired glucose tolerance	48.16	2	17391161 (1), 17878241 (1)
fatty liver	46.56	1	17006986 (1)
liver diseases	25.23	1	17006986 (1)
dyslipidemia	21.97	2	17068142 (1), 16700915 (1)
anorexia nervosa	17.56	1	17391161 (1)
cardiovascular diseases	17.39	1	16756736 (1)
inflammation	13.44	2	19136982 (1), 16700915 (1)

About this table

Genetic Association Database: ADIPOR2
Human Genome Epidemiology Navigator: ADIPOR2 (21 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/121 PubMed articles for ADIPOR2 gene (see all 121 ):

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. (PubMed id 12802337)^{2, 3, 4} Yamauchi T.... Kadowaki T. (2003)
Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. (PubMed id 15918014)^{1, 3, 6} Hara K....Kadowaki T. (2005)
Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. (PubMed id 15983228)^{1, 3, 6} Damcott C.M....Shuldiner A.R. (2005)
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. (PubMed id 16205883)^{1, 3, 6} Stefan N....Haring H.U. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population. (PubMed id 16505255)^{1, 3} Vaxillaire M....Froguel P. (2006)
The association of SNPs in ADIPOQ, ADIPOR1, and ADIPOR2 with insulin sensitivity in a cohort of adolescents and their parents. (PubMed id 19037660)^{1, 3} Rasmussen-Torvik L.J....Sinaiko A.R. (2009)
Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome. (PubMed id 16700915)^{1, 3} Broedl U.C....Parhofer K.G. (2006)
Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. (PubMed id 15105989)^{1, 3} Civitarese A.E....Ravussin E. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 79602	HGNC: 24041	AceView: ADIPOR2	Ensembl:ENSG00000006831	euGenes: HUgn79602
ECgene: ADIPOR2	H-InvDB: ADIPOR2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Adiponectin

Licensable Technologies for ADIPOR2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ADIPOR2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ADIPOR2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ADIPOR2		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ADIPOR2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Antibodies (Adiponectin Receptor 2)

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Search Novus for antibodies for ADIPOR2

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ADIPOR2 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for ADIPOR2

Summaries
for ADIPOR2

Genomic Location
for ADIPOR2

Proteins
for ADIPOR2

Protein Domains/
Families
for ADIPOR2

Gene Function
for ADIPOR2

Pathways & Interactions
for ADIPOR2

Drugs & Compounds
for ADIPOR2

Transcripts
for ADIPOR2

Expression
for ADIPOR2

Orthologs
for ADIPOR2

Paralogs
for ADIPOR2

SNPs/Variants
for ADIPOR2

Disorders & Mutations
for ADIPOR2

Medical News
for ADIPOR2

Publications
for ADIPOR2

Search for ADIPOR2

Genome Databases showing ADIPOR2

Other Databases showing ADIPOR2

Specialized Databases showing ADIPOR2

Licensable Technologies
for ADIPOR2

Services
for ADIPOR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ADIPOR2 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor ADIPOR2

Summariesfor ADIPOR2

Genomic Locationfor ADIPOR2

Proteinsfor ADIPOR2

Protein Domains/Familiesfor ADIPOR2

Gene Functionfor ADIPOR2

Pathways & Interactionsfor ADIPOR2

Drugs & Compoundsfor ADIPOR2

Transcriptsfor ADIPOR2

Expression for ADIPOR2

Orthologsfor ADIPOR2

Paralogsfor ADIPOR2

SNPs/Variantsfor ADIPOR2

Disorders & Mutationsfor ADIPOR2

Medical Newsfor ADIPOR2

Publicationsfor ADIPOR2

Search for ADIPOR2

Genome Databases showing ADIPOR2

Other Databases showing ADIPOR2

Specialized Databases showing ADIPOR2

Licensable Technologiesfor ADIPOR2

Servicesfor ADIPOR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ADIPOR2

Summaries
for ADIPOR2

Genomic Location
for ADIPOR2

Proteins
for ADIPOR2

Protein Domains/
Families
for ADIPOR2

Gene Function
for ADIPOR2

Pathways & Interactions
for ADIPOR2

Drugs & Compounds
for ADIPOR2

Transcripts
for ADIPOR2

Expression
for ADIPOR2

Orthologs
for ADIPOR2

Paralogs
for ADIPOR2

SNPs/Variants
for ADIPOR2

Disorders & Mutations
for ADIPOR2

Medical News
for ADIPOR2

Publications
for ADIPOR2

Licensable Technologies
for ADIPOR2

Services
for ADIPOR2