ADI1 Gene
protein-coding GIFtS : 54
GCID: GC02 M003501
acireductone dioxygenase 1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor ADI1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Acireductone Dioxygenase 1 1 2 HMFT16381 ARD1 2 3 1,2-Dihydroxy-3-Keto-5-Methylthiopentene Dioxygenase2 SIPL1 2 5 Ni-ARD2 APL11 2 Acireductone Dioxygenase (Ni(2+)-Requiring)2 MTCBP-11 3 Membrane-Type 1 Matrix Metalloproteinase Cytoplasmic Tail Binding Protein-12 Acireductone Dioxygenase (Fe(2+)-Requiring)2 3 MT1-MMP Cytoplasmic Tail-Binding Protein-12 Submergence-Induced Protein-Like Factor2 3 Submergence Induced Protein 22 Fe-ARD2 3 EC 1.13.11.543 MTCBP12 3 Sip-L3 FLJ109131 Membrane-Type 1 Matrix Metalloproteinase Cytoplasmic Tail-Binding Protein 13
Export aliases for ADI1 gene to outside databases Previous GC identifer: GC02M003480
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor ADI1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ADI1 : This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. (provided by RefSeq, May 2010) UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 Function : Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line Gene Wiki entry for ADI1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor ADI1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000002.11 NC_018913.1 NT_022221.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ADI1 gene promoter: USF1 C/EBPbeta USF2 USF-1:USF-2 POU6F1 (c2) Cdc5 POU2F1 POU2F1a USF-1 NF-kappaB1 Other transcription factors Search SABiosciences Chromatin IP Primers for ADI1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADI1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2p25.3 Ensembl cytogenetic band: 2p25.3 HGNC cytogenetic band: 2p25.2 ADI1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02M003501: view genomic region
(about GC identifiers )
Start:
3,501,690 bp from pter
End:
3,523,507 bp from pter
Size:
21,818 bases
Orientation:
minus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor ADI1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 (See
protein sequence )Recommended Name: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Size : 179 amino acids; 21498 Da
Cofactor : Binds 1 iron ion per monomer. Can also use other divalent metal cations (By similarity)
Subunit : Monomer (By similarity). Interacts with MMP14
Subcellular location : Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizesto the plasma membrane when complexed to MMP14
Sequence caution : Sequence=AAL25800.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAD38646.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAD96187.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions : D6W4Y3 Q53HW3 Q53QD3 Q57YV7 Q68CK2 Q6ZSF7 Q7Z512 Q96P85 Q9NV57Alternative splicing : 2 isoforms : Q9BV57-1 Q9BV57-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ADI1: NX_Q9BV57 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9BV57 ADI1 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_060739.2 ENSEMBL proteins: ENSP00000333666 ENSP00000371525 ENSP00000410178 Reactome Protein details: Q9BV57 Human Recombinant Protein Products: Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6 ): About this table
ADI1 for ontologies About GeneDecksing ADI1 Antibody Products: Assay Products for ADI1:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor ADI1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ADI1 for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9BV57 ProtoNet protein and cluster: Q9BV57
UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 Similarity : Belongs to the acireductone dioxygenase (ARD) family
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor ADI1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 Function : Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line Catalytic activity : 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-(methylthio)-2-oxobutanoate + formateEnzyme Number (IUBMB): EC 1.13.11.54 1
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ADI1 (NM_013358 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADI1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADI1
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADI1
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view) : About this table
ADI1 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor ADI1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 Methionine salvage pathway 2 Sulfur amino acid metabolism 3 Metabolism 4 Metabolism of amino acids and derivatives 5 methylthiopropionate biosynthesis
Pathway sources See GeneCards unified pathways Show all pathways 2 BioSystems Pathways for ADI1 5
Reactome Pathways for ADI1 2
Kegg Pathways (Kegg details for ADI1) :UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 Pathway : Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine fromS-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6
ADI1 for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADI1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)5/20 Interacting proteins for ADI1 (Q9BV57 1 , 3 ENSP00000333666 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 20 )
About this table Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0000096 sulfur amino acid metabolic process
TAS -- GO:0006595 polyamine metabolic process
TAS -- GO:0019509 L-methionine salvage from methylthioadenosine
TAS -- GO:0034641 cellular nitrogen compound metabolic process
TAS -- GO:0044281 small molecule metabolic process
TAS --
ADI1 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor ADI1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
ADI1 for compounds About GeneDecksing Browse Tocris compounds for ADI1 1 HMDB Compound for ADI1 About this table Compound Synonyms
CAS
# PubMed Ids Nickel Carbonyl nickel powder (see all 19 ) 7440-02-0 --
5 Novoseek chemical compound relationships for ADI1 gene About this table
Search CenterWatch for drugs/clinical trials and news about ADI1 / MTND
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor ADI1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ADI1 gene: NM_018269.3 Unigene Cluster for ADI1:
Acireductone dioxygenase 1 Hs.502773 [show with all ESTs ] Unigene Representative Sequence: AK127473 3 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000327435 (uc002qxp.4 ) ENST00000382093 (uc010yiq.2 ) ENST00000415131 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ADI1 (NM_013358 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADI1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADI1
Additional cDNA sequence: AB073609.1 AB158319.1 AF087863.1 AF403478.1 AK001775.1 AK127473.1 AK222467.1 AK225278.1 BC001467.2
21 DOTS entries : DT.446852 DT.99956085
DT.101985071 DT.92451152 DT.99988886 DT.100827485 DT.100827486 DT.100827475 DT.100827480 DT.97794559 DT.100700644 DT.100827474 DT.100827495 DT.120990091 DT.91832014 DT.92451148 DT.92451149 DT.95256744 DT.95256759 DT.100827487 DT.75162181 24/493 AceView cDNA sequences (see all 493 ):
CR593705 BF732945 CK819995 BQ225593 AI458820 BM978220 BM838044 BI545934 AI300683 AI476741 CR604779 AA725579 CR607574 CR592882 T35686 BQ005756 AA314427 AV653144 BC001467 AW075588 AA586973 BU621255 BM680542 BM998596 GeneLoc Exon Structure 4 Alternative Splicing Database (ASD) splice patterns (SP) for ADI1 About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c SP1 :   -           -         SP2 :                     SP3 :           -   -         SP4 :                    
ECgene alternative splicing isoforms for ADI1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for ADI1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ADI1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GCTTGGAGTT
About this image ADI1 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 2 LifeMap Cells Name Category PureStem™ progenitor E69 (Embryonic Progenitor Cell)PureStem™ progenitor T36 (Embryonic Progenitor Cell)Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See ADI1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ADI1 SOURCE GeneReport for Unigene cluster: Hs.502773 UniProtKB/Swiss-Prot: MTND_HUMAN, Q9BV57 Tissue specificity : Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney SABiosciences Expression via Pathway-Focused PCR Array including ADI1 : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ADI1Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ADI1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ADI1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ADI1 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADI1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor ADI1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for ADI1 gene from 8/29 species (see all 29 ) About this table
ENSEMBL Gene Tree for ADI1 (if available)TreeFam Gene Tree for ADI1 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor ADI1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ADI1 gene
ADI1 for paralogs About GeneDecksing 4 Pseudogenes.org Pseudogenes for ADI1 PGOHUM00000239760 PGOHUM00000244745 PGOHUM00000247657 PGOHUM00000249466
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor ADI1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 2 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ADI1 (3501690 - 3523507 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ADI1: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ADI1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor ADI1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ADI1 for disorders About GeneDecksing
OMIM gene information: 613400
OMIM disorders : --13 diseases for ADI1 : About MalaCards atopic dermatitis refsum disease intrahepatic cholangiocarcinoma klebsiella dermatitis hepatitis c cholangiocarcinoma hepatoblastoma influenza prostate cancer hepatitis pneumonia prostatitis Human Genome Epidemiology (HuGE) Navigator: ADI1 (1 document)Export disorders for ADI1 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor ADI1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ADI1 gene, integrated from 9 sources (see all 33 ): (articles sorted by number of sources associating them with ADI1) Utopia : connect your pdf to the dynamic world of online information
Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down- regulated in tumors. (PubMed id 14718544) 1 , 2 , 3, 9 Uekita T.... Seiki M. (2004) Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway. (PubMed id 15938715) 1 , 2 , 3 Hirano W.... Seiki M. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621) 1 , 2 Hillier L.W....Wilson R.K. (2005) Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005) 1 , 2 Yamada S....Nakagawara A. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Identification of a hepatic factor capable of supporting hepatitis C virus replication in a nonpermissive cell line. (PubMed id 11602742) 1 , 2 Yeh C.-T.... Liaw Y.-F. (2001) Expression and function of the human androgen-responsive gene ADI1 in prostate cancer. (PubMed id 17786183) 1 , 9 Oram S.W....Wang Z. (2007) 293 cells over-expressing human ADI1 and CD81 are per missive for serum-derived hepatitis C virus infection. (PubMed id 19626614) 1 , 9 Cheng J.C....Yeh C.T. (2009) Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing. (PubMed id 17212658) 1 , 9 Gotoh I....Seiki M. (2007)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for ADI1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing ADI1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing ADI1 gene
(According to HUGE )
About This Section --
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing ADI1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for ADI1 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for ADI1 gene: Search GeneIP for patents involving ADI1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor ADI1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for ADI1 OriGene shRNA RFP for ADI1 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ADI1 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ADI1 OriGene Protein Over-expression Lysate for ADI1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ADI1 OriGene 3'-UTR Clone for ADI1 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADI1 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for ADI1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ADI1 OriGene Custom Protein Services for ADI1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADI1 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ADI1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADI1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ADI1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ADI1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ADI1
Search Tocris compounds for ADI1
ADI1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADI1
ThermoFisher Antibodies for ADI1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADI1
Jump to Section...
Aliases for ADI1
Databases for ADI1
Disorders / Diseases for ADI1
Domains / Families for ADI1
Drugs / Compounds for ADI1
Expression for ADI1
Function for ADI1
Genomic Views for ADI1
Intellectual Property for ADI1
Orthologs for ADI1
Paralogs for ADI1
Pathways / Interactions for ADI1
Products for ADI1
Proteins for ADI1
Publications for ADI1
Search Box for ADI1
Summaries for ADI1
Transcripts for ADI1
Variants for ADI1
TOP
BOTTOM