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ADH1C Gene

protein-coding   GIFtS: 65

GC04M100457
alcohol dehydrogenase 1C (class I), gamma polypeptide
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ADH3)
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
ADH3 2, 3, 5
EC 1.1.1.1 3
Descriptions
ADH, gamma subunit 2
Alcohol dehydrogenase subunit gamma 3
alcohol dehydrogenase 1C (class I), gamma polypeptide 2
alcohol dehydrogenase 1C, gamma polypeptide 2
alcohol dehydrogenase 3 (class I), gamma polypeptide 2
aldehyde reductase 2
External Ids
HGNC: 2511
Entrez Gene: 1262
UniProtKB: P003263
Ensembl: ENSG000001877587
Search outside databases for aliases for ADH1C gene

Previous GC identifers: GC04M100504 GC04M100386 GC04M100452 GC04M100614

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ADH1C:
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol
dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates,
including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation
products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha,
beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in
ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in
a genomic segment as a gene cluster. [provided by RefSeq]

Gene Wiki entry for ADH1C
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADH1C gene  

Entrez Gene cytogenetic band: 4q21-q23   Ensembl cytogenetic band:  4q23   HGNC cytogenetic band: 4q23

ADH1C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M100457:     (about GC identifiers)

Start:
100,476,672 bp from pter
End:
100,492,940 bp from pter
Size:
16,269 bases
Orientation:
minus strand

1 alternative location:
Chr4- 100,416,547-100,431,165     
RefSeq DNA sequence:
NC_000004.10  NT_016354.18  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ADH1G_HUMAN, P00326 (See protein sequence)
Recommended Name: Alcohol dehydrogenase 1C  
Size: 375 amino acids; 39868 Da
Cofactor: Binds 2 zinc ions per subunit
Subunit: Dimer of identical or non-identical chains of three types; alpha, beta and gamma
Subcellular location: Cytoplasm
Miscellaneous: There are 7 different ADH's isozymes in human: three belongs to class-I: alpha,
beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to
class-V: ADH6
PDB structures from and Proteopedia :
1DDA (3D)    1HT0 (3D)    1U3W (3D)    
Secondary accessions: Q4PJ18 Q5WRV0 Q6LBW4 Q6NWV0 Q6NZA7

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_000660.1  

    ENSEMBL proteins: 
    ENSP00000209668 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ADH1C, pan ADH)
    Human Recombinant Proteins from Abnova (ADH1C)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    1 Gene Ontology (GO) cellular component term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm NAS--
    About this table

    Antibodies for ADH1C: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ADH1C
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (ADH1C, pan ADH), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ADH1C)
    Novus Biologicals Antibodies for ADH1C

    Assays for ADH1C: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    4 InterPro domains/families:
     IPR013149 ADH_Zn-bd
     IPR013154 ADH_GroES-like
     IPR002328 ADH_Zn_CS
     IPR002085 ADH_SF_Zn


       GeneDecks  ADH1C for the domains selected above  
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    Graphical View of Domain Structure for InterPro Entry P00326

    ProtoNet protein and cluster: P00326

    2 Blocks protein families:
    IPB002328 Zinc-containing alcohol dehydrogenase
    IPB013154 Alcohol dehydrogenase GroES-like


    UniProtKB/Swiss-Prot: ADH1G_HUMAN, P00326
    Similarity: Belongs to the zinc-containing alcohol dehydrogenase family

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADH1C)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADH1C)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000669

                  Applied Biosystems Silencer® siRNAs for ADH1C

                  Sigma-Aldrich siRNA and siRNA Panels for ADH1C  
                         Sigma-Aldrich shRNA for ADH1C  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ADH1C
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000669
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000669
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_000669 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_000669

    UniProtKB/Swiss-Prot: ADH1G_HUMAN, P00326
    Catalytic activity: An alcohol + NAD(+) = an aldehyde or ketone + NADH
    Enzyme Number (IUBMB): EC 1.1.1.1 

    3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Adh1):

    growth/sizehomeostasis/metabolismlife span-post-weaning/aging

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004024 alcohol dehydrogenase activity, zinc-dependent NAS2935875 6391921
    GO:0005488 binding IEA--
    GO:0008270 zinc ion binding IEA--
    GO:0016491 oxidoreductase activity IEA--
    GO:0046872 metal ion binding IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    4 Invitrogen iPath™ Online BioAtlas - Pathways for ADH1C (Maps provided by GeneGo):
     Glycolysis and gluconeogenesis
     Regulation of lipid metabolism via PPAR, RXR and VDR
     Cholesterol metabolism III. Biosynthesis of bile acid
     Tyrosine metabolism

       GeneDecks  ADH1C for the pathways selected above  
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    5/6 Sigma-Aldrich "Your Favorite Gene" Pathways for  ADH1C  (Your Favorite Gene powered by Ingenuity) (see all 6
     Glycerolipid Metabolism
     Glycolysis/Gluconeogenesis
     Metabolism of Xenobiotics by Cytochrome P450
     Fatty Acid Metabolism
     Bile Acid Biosynthesis

       GeneDecks  ADH1C for the pathways selected above  
    About GeneDecksing

    5/9 Kegg Pathways  (Kegg details for ADH1C) (see all 9 ):
     hsa00010 Glycolysis / Gluconeogenesis
     hsa00071 Fatty acid metabolism
     hsa00120 Bile acid biosynthesis
     hsa00350 Tyrosine metabolism
     hsa00624 1- and 2-Methylnaphthalene degradation

       GeneDecks  ADH1C for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  ADH1C 


    5/37 Interacting proteins for ADH1C (ENSP000002096683) via UniProtKB, MINT, and/or STRING (see all 37 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALDH2ENSP000002617333STRING (score=.993)
    ADHFE1ENSP000002765763STRING (score=.992)
    ALDH3A1ENSP000003345903STRING (score=.969)
    AVPENSP000003696473STRING (score=.955)
    ALDH1A3ENSP000003322563STRING (score=.952)
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006066 cellular alcohol metabolic process NAS--
    GO:0055114 oxidation reduction IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Sigma-Aldrich Small Molecules for ADH1C:
    Inhibitor

    Browse Tocris compounds for ADH1C
    4 Novoseek chemical compound relationships for ADH1C gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    rsai 73.30 3 10925369 (1), 15318112 (1), 9731720 (1)
    ethanol 62.78 16 15602753 (2), 11700261 (2), 19120062 (1), 17204375 (1) (see all 11)
    p002 21.73 1 11207350 (1)
    oligonucleotide 0.00 1 9063814 (1)
    About this table

    2 PharmGKB drug compound relationships for ADH1C gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    ethanolPD  GN  9731720
    xenobioticsFA  GN  12367788
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADH1C)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADH1C)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000669

                  Sigma-Aldrich siRNA and siRNA Panels for ADH1C  
                         Sigma-Aldrich shRNA for ADH1C  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_000669  

    REFSEQ mRNAs for ADH1C gene: 

    NM_000669.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_000669  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000669
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000669
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_000669 

    Additional cDNA sequence: 

    BC062476.1 BC066227.1 BC066228.1 BC067419.1 BC067420.1 BC067421.1 BC067422.1 BC074771.2 
    BC074786.2 M12272.1 X04299.1 X04350.1 

    13 DOTS entries:

    DT.100030344  DT.95158774  DT.101985268  DT.415876  DT.100798841  DT.101985267  DT.121224284  DT.100798849 
    DT.91692319  DT.121224280  DT.100798839  DT.121224262  DT.95158779 

    24/475 AceView cDNA sequences (see all 475 ):

    CB138477 CD172162 NM_000667 AA416884 CB162202 CD014078 AI275907 BM994680 
    BG149939 X04350 BP381861 BG564896 AU122403 BG546605 AA634614 CB147187 
    BQ786902 CB266463 M12963 CB148959 CB157572 BP381206 CB141250 AI262943 

    highest scoring ESTs for ADH1C:

    M12272 BC062476 BC066227 BC066228 BC067419 BC067420 BC067421 BC067422 CB114902 CB114919 

    Unigene Cluster for ADH1C:

    Alcohol dehydrogenase 1C (class I), gamma polypeptide
    Hs.654537  [show with all ESTs]
    Unigene Representative Sequence: NM_000669


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ADH1C

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                                      -           -     -     -     -     -               
    SP2:                                            -                                             
    SP3:                                      -                                                   
    SP4:                                                                                          

    About this scheme

    ECgene alternative splicing isoforms for ADH1C

    1 Ensembl transcript including schematic representation:
    ENST00000209668  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADH1C expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADH1C

    1 / 2 / 3

    4 probe-sets matching ADH1C gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    36247_f_at2, 3 U95-A 3 1.00 0.64 0.99 0.86 M12272 1.00 0.87 0.94 1
    34637_f_at2, 3 U95-A 3 1.00 0.33 0.98 1.15 M12963 0.60 0.33 0.49 2

    206262_at2, 3 U133-A 1 1.00 1.00 -- -- NM_000669 0.60 0.78 0.69 1

    206262_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ADH1C for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ATCTGGAGCA

    SOURCE GeneReport for Unigene cluster: Hs.654537

    Expression variation in blood from EXPOLDB for ADH1C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ADH1C gene from 5/8 species (see all 8 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ADH1C1   -- alcohol dehydrogenase 1C (class I), gamma polypeptide 85.96(n)
    86.67(a)
    478489  XM_535667.2  XP_535667.2 
    chimpanzee
    (Pan troglodytes)
    ADH1C1   -- alcohol dehydrogenase 1C (class I), gamma polypeptide 99.38(n)
    99.47(a)
    744176  XM_001167058.1  XP_001167058.1 
    cow
    (Bos taurus)
    ADH1C1   -- alcohol dehydrogenase 1C (class I), gamma polypeptide 85.51(n)
    84.53(a)
    509744  XM_586772.3  XP_586772.3 
    rat
    (Rattus norvegicus)
    Adh11   -- alcohol dehydrogenase 1 (class I) 81.49(n)
    82.76(a)
    24172  XM_001053019.1  XP_001053019.1 
    mouse
    (Mus musculus)
    Adh11, 5 3 (71.20 cM)5
    alcohol dehydrogenase 1 (class I)1, 5 82.22(n)1
    85.07(a)1
    115221  NM_007409.21  NP_031435.11 
     AI1948265  AI8502785  (see all 30)
    About this table        Species with no ortholog for ADH1C

    ENSEMBL Gene Tree for ADH1C
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADH1C gene
    ADH42  ADH1B2  ADH52  ADH72  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section

    UniProtKB/Swiss-Prot: ADH1G_HUMAN, P00326
    Polymorphism: Two main alleles are known, ADH3*1 or gamma-1 has Arg-272/Ile-350 while ADH3*2 or
    gamma-2 has Gln-272/Val-350. ADH3*1 is associated with a fast rate of ethanol oxidation and ADH3*2
    with a slow rate


    10/262 NCBI SNPs in ADH1C are shown (see all 262 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 93)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 4 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs31140461,2
    A,C,F,H,O100476455(+) TTACCC/TTAGGG 1 -- ng5112Minor allele frequency- T:0.04NA NS EU EA WA 680
    rs22987531,2
    C,F,H,O100476930(+) TATTGT/CTTCAA 1 -- ut3121Minor allele frequency- C:0.05EA NA EU WA NS 2338
    rs17899241,2
    C,F,H,O100493309(+) AGTTAC/TGAAGG 1 -- ng3113Minor allele frequency- T:0.20NA MN EA EU WA 1276
    rs16934821,2
    C,F,H100482988(+) CAAGCC/TGACCG 1 R/Q mis115Minor allele frequency- T:0.24MN CSAM EA NS EU WA NA 1066
    rs170288601,2
    C,F,H100476233(+) GAACCT/AAAGTT 1 -- ng5111Minor allele frequency- A:0.01NA EU EA WA 968
    rs175861631,2
    C,F,H100493594(+) GGTTAT/CGACAC 1 -- ng317Minor allele frequency- C:0.06NA EU EA WA 562
    rs114998231,2
    C,F,H100493772(-) ACAACT/CCTGGA 1 -- ng319Minor allele frequency- C:0.05EU EA WA NS 594
    --
    rs16934681,2
    C,F100494838(+) CCTATC/GAAAAA 1 -- ng315Minor allele frequency- G:0.12NS 190
    rs41475411,2
    C,F100493180(-) AGGAAG/CTTGAG 1 -- ng3110Minor allele frequency- C:0.47NA MN EA NS 658
    --
    rs17899251,2
    C,F100494768(+) ACCATT/CTTGTT 1 -- ng315Minor allele frequency- C:0.22NS 190
    About this table

    HapMap Linkage Disequilibrium images for ADH1C (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 103730   disorders: 168600  

    10/28 Novoseek disease relationships for ADH1C gene (see all 28 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    alcoholism 77.42 31 15519646 (3), 8773821 (3), 12710951 (2), 15902904 (2) (see all 20)
    pharyngeal cancer 70.14 3 9637146 (1), 10925369 (1), 9390539 (1)
    pancreatitis alcoholic 64.04 3 8985275 (1), 15220553 (1), 8986224 (1)
    alcoholic cirrhosis 59.81 5 1592339 (2), 15220553 (1), 11748356 (1), 11966948 (1)
    liver diseases alcoholic 58.88 5 15519646 (3), 9731720 (2)
    chronic pancreatitis 49.97 5 16239350 (1), 17454860 (1), 18773092 (1), 11966948 (1) (see all 5)
    oropharyngeal cancer 43.92 1 9050916 (1)
    oral cancer 43.81 2 11802217 (1)
    cirrhosis 42.50 7 8985275 (1), 17454860 (1), 1592339 (1), 15519646 (1) (see all 5)
    pancreatitis 41.54 1 8985275 (1)
    About this table

    2 PharmGKB disease relationships for ADH1C gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Liver Diseases, AlcoholicPD  GN  9731720
    Lung NeoplasmsFA  GN  12367788
    About this table

    Human Gene Mutation Database: ADH1C
    Genetic Association Database: ADH1C
    Human Genome Epidemiology Navigator: ADH1C (104 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/208 PubMed articles for ADH1C gene (see all 208 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 126 HGNC: 251 AceView: ADH1AandADH1BandADH1C Ensembl:ENSG00000187758 euGenes: HUgn126
    ECgene: ADH1C H-InvDB: ADH1C
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    NIEHS-SNPshttp://egp.gs.washington.edu/data/adh1c/
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADH1C:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADH1C-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADH1C Antibodies for ADH1C
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADH1C Small molecules for ADH1C
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