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Aliases for ADGRG3 Gene

Aliases for ADGRG3 Gene

  • Adhesion G Protein-Coupled Receptor G3 2 3
  • G-Protein Coupled Receptor PGR26 3 4
  • G Protein-Coupled Receptor 97 2 3
  • GPR97 3 4
  • PGR26 3 4
  • Probable G-Protein Coupled Receptor 97 3
  • PB99 3

External Ids for ADGRG3 Gene

Previous Symbols for ADGRG3 Gene

  • GPR97

Summaries for ADGRG3 Gene

GeneCards Summary for ADGRG3 Gene

ADGRG3 (Adhesion G Protein-Coupled Receptor G3) is a Protein Coding gene. An important paralog of this gene is ADGRG5.

UniProtKB/Swiss-Prot for ADGRG3 Gene

  • Orphan receptor

Gene Wiki entry for ADGRG3 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRG3 Gene

Genomics for ADGRG3 Gene

Genomic Location for ADGRG3 Gene

Start:
57,668,187 bp from pter
End:
57,689,378 bp from pter
Size:
21,192 bases
Orientation:
Plus strand

Genomic View for ADGRG3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ADGRG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADGRG3 Gene

No data available for Regulatory Elements for ADGRG3 Gene

Proteins for ADGRG3 Gene

  • Protein details for ADGRG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86Y34-GPR97_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 97
    Protein Accession:
    Q86Y34
    Secondary Accessions:
    • Q6ZMF4
    • Q86SL9
    • Q8IZF1

    Protein attributes for ADGRG3 Gene

    Size:
    549 amino acids
    Molecular mass:
    60861 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18774.1; Type=Frameshift; Positions=492; Evidence={ECO:0000305};

neXtProt entry for ADGRG3 Gene

Proteomics data for ADGRG3 Gene at MOPED

Post-translational modifications for ADGRG3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ADGRG3 Gene

No data available for DME Specific Peptides for ADGRG3 Gene

Domains for ADGRG3 Gene

Gene Families for ADGRG3 Gene

HGNC:
  • GPCRBO :GPCR / Class B : Orphans

UniProtKB/Swiss-Prot:

GPR97_HUMAN
Domain:
  • Contains 1 GPS domain.:
    • Q86Y34
Family:
  • Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.:
    • Q86Y34
genes like me logo Genes that share domains with ADGRG3: view

Function for ADGRG3 Gene

Molecular function for ADGRG3 Gene

UniProtKB/Swiss-Prot Function: Orphan receptor

Gene Ontology (GO) - Molecular Function for ADGRG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity --
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with ADGRG3: view

Phenotypes for ADGRG3 Gene

MGI mutant phenotypes for ADGRG3:
inferred from 1 alleles
GenomeRNAi human phenotypes for ADGRG3:
genes like me logo Genes that share phenotypes with ADGRG3: view

Animal Models for ADGRG3 Gene

MGI Knock Outs for ADGRG3:

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for ADGRG3 Gene

Localization for ADGRG3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADGRG3 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for ADGRG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ADGRG3: view

Pathways for ADGRG3 Gene

SuperPathways for ADGRG3 Gene

No Data Available

Interacting Proteins for ADGRG3 Gene

Gene Ontology (GO) - Biological Process for ADGRG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007166 cell surface receptor signaling pathway --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007218 neuropeptide signaling pathway --
genes like me logo Genes that share ontologies with ADGRG3: view

No data available for Pathways by source for ADGRG3 Gene

Transcripts for ADGRG3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ADGRG3 Gene

No ASD Table

Relevant External Links for ADGRG3 Gene

GeneLoc Exon Structure for
ADGRG3
ECgene alternative splicing isoforms for
ADGRG3

Expression for ADGRG3 Gene

mRNA expression in normal human tissues for ADGRG3 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ADGRG3 Gene

genes like me logo Genes that share expressions with ADGRG3: view

Orthologs for ADGRG3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ADGRG3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR97 36
  • 89.94 (n)
  • 87.55 (a)
GPR97 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GPR97 36
  • 77.27 (n)
  • 67.99 (a)
GPR97 37
  • 66 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPR97 36
  • 76.54 (n)
  • 68.68 (a)
GPR97 37
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpr97 36
  • 75.76 (n)
  • 69.76 (a)
Gpr97 16
Gpr97 37
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPR97 37
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPR97 37
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpr97 36
  • 76.14 (n)
  • 70.66 (a)
chicken
(Gallus gallus)
Aves GPR97 36
  • 56.04 (n)
  • 41 (a)
GPR97 37
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii GPR97 37
  • 28 (a)
OneToOne
LOC799479 36
  • 51.31 (n)
  • 38.92 (a)
Species with no ortholog for ADGRG3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ADGRG3 Gene

ENSEMBL:
Gene Tree for ADGRG3 (if available)
TreeFam:
Gene Tree for ADGRG3 (if available)

Paralogs for ADGRG3 Gene

genes like me logo Genes that share paralogs with ADGRG3: view

Variants for ADGRG3 Gene

Sequence variations from dbSNP and Humsavar for ADGRG3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs727215 -- 57,684,910(+) gattc(A/C)cagta intron-variant
rs727216 -- 57,684,871(+) ccagc(C/G)aggtg intron-variant
rs727217 -- 57,684,658(+) GCCTA(A/G)AGAGA intron-variant
rs730733 -- 57,677,167(+) GAAAG(C/T)TGGGG intron-variant
rs731960 -- 57,686,329(-) AAAAC(A/G)GCATG intron-variant

Relevant External Links for ADGRG3 Gene

HapMap Linkage Disequilibrium report
ADGRG3

No data available for Structural Variations from Database of Genomic Variants (DGV) for ADGRG3 Gene

Disorders for ADGRG3 Gene

No disorders were found for ADGRG3 Gene.

No data available for UniProtKB/Swiss-Prot for ADGRG3 Gene

Publications for ADGRG3 Gene

  1. Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions. (PMID: 12435584) Fredriksson R. … Schioeth H.B. (FEBS Lett. 2002) 2 3 4
  2. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for ADGRG3 Gene

Sources for ADGRG3 Gene

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