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Aliases for ADGRF2 Gene

Aliases for ADGRF2 Gene

  • Adhesion G Protein-Coupled Receptor F2 2 3
  • G Protein-Coupled Receptor 111 2 3
  • GPR111 3 4
  • PGR20 3 4
  • Probable G-Protein Coupled Receptor 111 3
  • G-Protein Coupled Receptor PGR20 4
  • HGPCR35 3

External Ids for ADGRF2 Gene

Previous HGNC Symbols for ADGRF2 Gene

  • GPR111

Summaries for ADGRF2 Gene

GeneCards Summary for ADGRF2 Gene

ADGRF2 (Adhesion G Protein-Coupled Receptor F2) is a Protein Coding gene. An important paralog of this gene is ADGRG7.

UniProtKB/Swiss-Prot for ADGRF2 Gene

  • Orphan receptor

Gene Wiki entry for ADGRF2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRF2 Gene

Genomics for ADGRF2 Gene

Genomic Location for ADGRF2 Gene

Start:
47,656,436 bp from pter
End:
47,697,797 bp from pter
Size:
41,362 bases
Orientation:
Plus strand

Genomic View for ADGRF2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ADGRF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADGRF2 Gene

No data available for Regulatory Elements for ADGRF2 Gene

Proteins for ADGRF2 Gene

  • Protein details for ADGRF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZF7-GP111_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 111
    Protein Accession:
    Q8IZF7
    Secondary Accessions:
    • Q2PNZ1
    • Q86SL6
    • Q8NGU5
    • Q8TDT5

    Protein attributes for ADGRF2 Gene

    Size:
    708 amino acids
    Molecular mass:
    78569 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05907.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ADGRF2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ADGRF2 Gene

Proteomics data for ADGRF2 Gene at MOPED

Post-translational modifications for ADGRF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ADGRF2 Gene

No data available for DME Specific Peptides for ADGRF2 Gene

Domains for ADGRF2 Gene

Gene Families for ADGRF2 Gene

HGNC:
  • GPCRBO :GPCR / Class B : Orphans

Protein Domains for ADGRF2 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8IZF7

UniProtKB/Swiss-Prot:

GP111_HUMAN :
  • Q8IZF7
Domain:
  • Contains 1 GPS domain.
Family:
  • Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
genes like me logo Genes that share domains with ADGRF2: view

No data available for Suggested Antigen Peptide Sequences for ADGRF2 Gene

Function for ADGRF2 Gene

Molecular function for ADGRF2 Gene

UniProtKB/Swiss-Prot Function: Orphan receptor

Gene Ontology (GO) - Molecular Function for ADGRF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity --
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with ADGRF2: view

Phenotypes for ADGRF2 Gene

genes like me logo Genes that share phenotypes with ADGRF2: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ADGRF2 Gene

Localization for ADGRF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADGRF2 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for ADGRF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ADGRF2: view

No data available for Subcellular locations from COMPARTMENTS for ADGRF2 Gene

Pathways for ADGRF2 Gene

SuperPathways for ADGRF2 Gene

No Data Available

Interacting Proteins for ADGRF2 Gene

Gene Ontology (GO) - Biological Process for ADGRF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007166 cell surface receptor signaling pathway --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007218 neuropeptide signaling pathway --
genes like me logo Genes that share ontologies with ADGRF2: view

No data available for Pathways by source for ADGRF2 Gene

Transcripts for ADGRF2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ADGRF2 Gene

No ASD Table

Relevant External Links for ADGRF2 Gene

GeneLoc Exon Structure for
ADGRF2
ECgene alternative splicing isoforms for
ADGRF2

Expression for ADGRF2 Gene

mRNA expression in normal human tissues for ADGRF2 Gene

genes like me logo Genes that share expressions with ADGRF2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ADGRF2 Gene

Orthologs for ADGRF2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ADGRF2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR111 35
  • 99.38 (n)
  • 98.75 (a)
GPR111 36
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GPR111 35
  • 82.29 (n)
  • 79.72 (a)
GPR111 36
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPR111 35
  • 85.77 (n)
  • 85.51 (a)
GPR111 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpr111 35
  • 78.86 (n)
  • 76.11 (a)
Gpr111 16
Gpr111 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPR111 36
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPR111 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpr111 35
  • 79.05 (n)
  • 76.71 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 48 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX545917.1 36
  • 27 (a)
ManyToMany
CABZ01002470.1 36
  • 36 (a)
ManyToMany
si:dkey-13i15.1 36
  • 11 (a)
ManyToMany
si:dkey-30j22.12 36
  • 22 (a)
ManyToMany
si:dkey-30j22.2 36
  • 20 (a)
ManyToMany
si:dkey-30j22.4 36
  • 25 (a)
ManyToMany
Species with no ortholog for ADGRF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ADGRF2 Gene

ENSEMBL:
Gene Tree for ADGRF2 (if available)
TreeFam:
Gene Tree for ADGRF2 (if available)

Paralogs for ADGRF2 Gene

Paralogs for ADGRF2 Gene

genes like me logo Genes that share paralogs with ADGRF2: view

Variants for ADGRF2 Gene

Sequence variations from dbSNP and Humsavar for ADGRF2 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs868881 -- 47,673,039(-) AGCCT(A/G)TATTC intron-variant
rs869002 -- 47,672,361(+) GAAAA(C/T)GAATT intron-variant
rs997430 -- 47,692,080(-) GAAAT(G/T)ACTAG intron-variant
rs997431 -- 47,691,736(-) TGACC(C/G)AGGCA intron-variant
rs1021231 -- 47,656,897(+) TTTAC(A/G)TAATA intron-variant

Relevant External Links for ADGRF2 Gene

HapMap Linkage Disequilibrium report
ADGRF2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ADGRF2 Gene

Disorders for ADGRF2 Gene

No disorders were found for ADGRF2 Gene.

No data available for UniProtKB/Swiss-Prot for ADGRF2 Gene

Publications for ADGRF2 Gene

  1. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 3 4
  2. Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions. (PMID: 12435584) Fredriksson R. … Schioeth H.B. (FEBS Lett. 2002) 2 3
  3. There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini. (PMID: 12565841) Fredriksson R. … Schioeth H.B. (Biochem. Biophys. Res. Commun. 2003) 3 4
  4. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4

Products for ADGRF2 Gene

Sources for ADGRF2 Gene

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