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Aliases for ADGRE4P Gene

Aliases for ADGRE4P Gene

  • Adhesion G Protein-Coupled Receptor E4, Pseudogene 2 3
  • Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 4 Pseudogene 2 3
  • G Protein-Coupled Receptor 127 2 3
  • GPR127 3 6
  • EMR4P 3 6
  • FIRE 3 6
  • EMR4 3 6
  • Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 4 2
  • EGF-TM7 Receptor EMR4 3
  • PGR16 3

External Ids for ADGRE4P Gene

Previous Symbols for ADGRE4P Gene

  • GPR127
  • EMR4
  • EMR4P

Summaries for ADGRE4P Gene

Entrez Gene Summary for ADGRE4P Gene

  • This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]

GeneCards Summary for ADGRE4P Gene

ADGRE4P (Adhesion G Protein-Coupled Receptor E4, Pseudogene) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRE4P Gene

Genomics for ADGRE4P Gene

Genomic Location for ADGRE4P Gene

Start:
6,952,500 bp from pter
End:
6,990,846 bp from pter
Size:
38,347 bases
Orientation:
Minus strand

Genomic View for ADGRE4P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ADGRE4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADGRE4P Gene

No data available for Regulatory Elements for ADGRE4P Gene

Proteins for ADGRE4P Gene

Post-translational modifications for ADGRE4P Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADGRE4P Gene

Domains for ADGRE4P Gene

Gene Families for ADGRE4P Gene

HGNC:
  • GPCRBO :GPCR / Class B : Orphans
genes like me logo Genes that share domains with ADGRE4P: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for ADGRE4P Gene

Function for ADGRE4P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ADGRE4P Gene

Localization for ADGRE4P Gene

No data available for Gene Ontology (GO) - Cellular Components for ADGRE4P Gene

Pathways for ADGRE4P Gene

SuperPathways for ADGRE4P Gene

No Data Available

Interacting Proteins for ADGRE4P Gene

Gene Ontology (GO) - Biological Process for ADGRE4P Gene

None

No data available for Pathways by source for ADGRE4P Gene

Transcripts for ADGRE4P Gene

mRNA/cDNA for ADGRE4P Gene

(1) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ADGRE4P Gene

No ASD Table

Relevant External Links for ADGRE4P Gene

GeneLoc Exon Structure for
ADGRE4P
ECgene alternative splicing isoforms for
ADGRE4P

Expression for ADGRE4P Gene

mRNA expression in normal human tissues for ADGRE4P Gene

genes like me logo Genes that share expressions with ADGRE4P: view

Orthologs for ADGRE4P Gene

Evolution for ADGRE4P Gene

ENSEMBL:
Gene Tree for ADGRE4P (if available)
TreeFam:
Gene Tree for ADGRE4P (if available)

No data available for Orthologs for ADGRE4P Gene

Paralogs for ADGRE4P Gene

No data available for Paralogs for ADGRE4P Gene

Variants for ADGRE4P Gene

Sequence variations from dbSNP and Humsavar for ADGRE4P Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs166156 -- 6,973,716(-) ttttt(G/T)ttttt intron-variant
rs252567 -- 6,978,701(+) atttt(C/G)atcta intron-variant
rs252568 -- 6,978,439(+) taaat(A/C)aatca intron-variant
rs252569 -- 6,978,002(+) GCCAA(C/T)GGATC intron-variant
rs252570 -- 6,976,834(+) AGTCA(C/T)GCACC intron-variant

Relevant External Links for ADGRE4P Gene

HapMap Linkage Disequilibrium report
ADGRE4P

No data available for Structural Variations from Database of Genomic Variants (DGV) for ADGRE4P Gene

Disorders for ADGRE4P Gene

No disorders were found for ADGRE4P Gene.

No data available for UniProtKB/Swiss-Prot for ADGRE4P Gene

Publications for ADGRE4P Gene

  1. There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini. (PMID: 12565841) Fredriksson R. … Schioeth H.B. (Biochem. Biophys. Res. Commun. 2003) 2 3 23
  2. Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence. (PMID: 12731063) Hamann J. … van Lier R.A.W. (Eur. J. Immunol. 2003) 3 23
  3. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. (PMID: 25713288) Hamann J. … SchiAPth H.B. (Pharmacol. Rev. 2015) 2 3
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ADGRE4P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate ADGRE4P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ADGRE4P
    • Block miRNA regulation of ADGRE4P using miScript Target Protectors

    Sources for ADGRE4P Gene

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