Aliases for ADGRB2 Gene
Aliases for ADGRB2 Gene
External Ids for ADGRB2 Gene
- HGNC: 944
- Entrez Gene: 576
- Ensembl: ENSG00000121753
- OMIM: 602683
- UniProtKB: O60241
Previous HGNC Symbols for ADGRB2 Gene
- BAI2
Summaries for ADGRB2 Gene
-
This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for ADGRB2 Gene
ADGRB2 (Adhesion G Protein-Coupled Receptor B2) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRB3.
UniProtKB/Swiss-Prot for ADGRB2 Gene
-
Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRB2 Gene
Genomics for ADGRB2 Gene
Regulatory Elements for ADGRB2 Gene
Enhancers for ADGRB2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ADGRB2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ADGRB2 Gene
- Chromosome:
- 1
- Start:
- 31,727,105 bp from pter
- End:
- 31,764,893 bp from pter
- Size:
- 37,789 bases
- Orientation:
- Minus strand
Genomic View for ADGRB2 Gene
Genes around ADGRB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p35.2 by Ensembl
- 1p35.2 by Entrez Gene
- 1p35.2 by HGNC
ADGRB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADGRB2 Gene
Proteins for ADGRB2 Gene
-
Protein details for ADGRB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60241-AGRB2_HUMAN
- Recommended name:
- Adhesion G protein-coupled receptor B2
- Protein Accession:
- O60241
- B9EGK9
- Q5T6K0
- Q8NGW8
- Q96GZ9
Protein attributes for ADGRB2 Gene
- Size:
- 1585 amino acids
- Molecular mass:
- 172656 Da
- Quaternary structure:
-
- Heterodimer of 2 chains generated by proteolytic processing; the large extracellular N-terminal fragment and the membrane-bound C-terminal fragment predominantly remain associated and non-covalently linked. Interacts with GABPB2 (By similarity). Interacts (via carboxy-terminus) with TAX1BP3 (PubMed:21787750).
- SequenceCaution:
-
- Sequence=BAA25362.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI16890.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for ADGRB2 Gene
Post-translational modifications for ADGRB2 Gene
- Glycosylated.
- Proteolytically cleaved at 2 conserved sites: one in the GPS domain (S1 site) and the other in the middle of the extracellular domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. Furin is involved in the cleavage of the S2 site generating a soluble fragment.
- Glycosylation at Asn106, Asn191, posLast=192192, Asn356, posLast=437437, Asn560, posLast=645645, and Asn867
- Modification sites at PhosphoSitePlus
Other Protein References for ADGRB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam antibodies for ADGRB2
- Invitrogen Antibodies for ADGRB2
- antibodies-online Antibodies for ADGRB2: See all 66
- GeneTex ADGRB2 antibody for ADGRB2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ADGRB2
Protein Products
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-
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- Novus Biologicals proteins for ADGRB2
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-
Abcam proteins for ADGRB2
No data available for DME Specific Peptides for ADGRB2 Gene
Domains & Families for ADGRB2 Gene
Gene Families for ADGRB2 Gene
Protein Domains for ADGRB2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ADGRB2 Gene
Graphical View of Domain Structure for InterPro Entry
O60241UniProtKB/Swiss-Prot:
AGRB2_HUMAN :- Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
- Family:
-
- Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Function for ADGRB2 Gene
Molecular function for ADGRB2 Gene
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Displays increased activity following removal of N-terminal regions (mimicking the situation after proteolytic cleavage in the GPS domain and N-terminal fragment release).
- UniProtKB/Swiss-Prot Function:
- Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | IEA | -- |
| GO:0004930 | G-protein coupled receptor activity | TAS,IEA | -- |
Phenotypes for ADGRB2 Gene
- MGI mutant phenotypes for ADGRB2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ADGRB2:
Animal Model Products
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miRNA for ADGRB2 Gene
- miRTarBase miRNAs that target ADGRB2
miRNA Products
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Inhibitory RNA Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for ADGRB2 (BAI2)
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADGRB2 Gene
Localization for ADGRB2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADGRB2 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | TAS,IEA | -- |
Pathways & Interactions for ADGRB2 Gene
No Data Available
Interacting Proteins for ADGRB2 Gene
Selected Interacting proteins:
O60241-AGRB2_HUMAN
ENSP00000362762
for ADGRB2 Gene via
MINT
STRING
IID
| Symbol | External ID(s) | Details |
|---|---|---|
| GABPA | ||
| GABPB1 | ||
| GABPB1-IT1 | ||
| SHANK1 | ||
| ARHGAP1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007166 | cell surface receptor signaling pathway | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS,IEA | -- |
| GO:0007422 | peripheral nervous system development | IEA | -- |
| GO:0016525 | negative regulation of angiogenesis | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ADGRB2 Gene
Transcripts for ADGRB2 Gene
mRNA/cDNA for ADGRB2 Gene
- (20) REFSEQ mRNAs :
- (86) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
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-
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miRNA Products
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Inhibitory RNA Products
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Clone Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for ADGRB2 (BAI2)
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: |
| ExUns: | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 | ^ | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28a | · | 28b | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | · | 31c | ^ | 32 | ^ | 33 | ^ | 34a | · | 34b | ^ | 35a | · | 35b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: |
Expression for ADGRB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
- Intraembryonic Epiblast Cells Epiblast
This gene is overexpressed in Cerebrospinal fluid (57.4) and Vitreous humor (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ADGRB2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ADGRB2 Gene:
ADGRB2mRNA Expression by UniProt/SwissProt for ADGRB2 Gene:
O60241-AGRB2_HUMAN
Tissue specificity:
Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Evidence on tissue expression from TISSUES for ADGRB2 Gene
- Nervous system(4.9)
Primer Products
-
OriGene qPCR primer pairs for ADGRB2
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADGRB2 Gene
Orthologs for ADGRB2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BAI2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | BAI2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | BAI2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Bai2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Bai2 34 35 |
|
||
| Adgrb2 16 |
|
||||
| platypus (Ornithorhynchus anatinus) |
Mammalia | BAI2 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| chicken (Gallus gallus) |
Aves | BAI2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | bai2 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | BAI2 35 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | unc-5 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | T21B6.3 35 |
|
ManyToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5741 35 |
|
ManyToMany |
- Species where no ortholog for ADGRB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ADGRB2 Gene
Variants for ADGRB2 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000245649 | -- | 31,730,894(+) | TGGGT(A/G)TCGGC | nc-transcript-variant, reference, missense | |
| rs1000296450 | -- | 31,730,637(+) | CAGAC(A/G)CCACG | intron-variant, downstream-variant-500B | |
| rs1000296809 | -- | 31,743,057(+) | ACCAC(C/G/T)GGCGC | intron-variant | |
| rs1000351829 | -- | 31,731,497(+) | GGGAG(G/T)TACCA | intron-variant | |
| rs1000491103 | -- | 31,761,209(+) | GTCCG(C/G)CCACA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758930 | CNV | loss | 17122850 |
| nsv1007390 | CNV | gain | 25217958 |
| nsv1007786 | CNV | gain | 25217958 |
| nsv1121760 | CNV | deletion | 24896259 |
| nsv461028 | CNV | loss | 19166990 |
| nsv545953 | CNV | loss | 21841781 |
| nsv950385 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
5.68% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.77;
66.68% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ADGRB2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ADGRB2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADGRB2 Gene
Disorders for ADGRB2 Gene
Relevant External Links for ADGRB2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ADGRB2
No disorders were found for ADGRB2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADGRB2 Gene
Publications for ADGRB2 Gene
- Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). (PMID: 9533023) Shiratsuchi T. … Tokino T. (Cytogenet. Cell Genet. 1997) 2 3 4 22 64
- International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. (PMID: 25713288) Hamann J. … SchiAPth H.B. (Pharmacol. Rev. 2015) 2 3 4 64
- Identification of brain-specific angiogenesis inhibitor 2 as an interaction partner of glutaminase interacting protein. (PMID: 21787750) Zencir S. … Mohanty S. (Biochem. Biophys. Res. Commun. 2011) 3 4 64
- Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing. (PMID: 20367554) Okajima D. … Yokota H. (J. Recept. Signal Transduct. Res. 2010) 3 4 64
- Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor. (PMID: 16412436) Jeong B.C. … Kim K.K. (FEBS Lett. 2006) 3 22 64
Products for ADGRB2 Gene
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- Mammalian expression: PiggyBac
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- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ADGRB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio