Aliases for ADGRB2 Gene
Aliases for ADGRB2 Gene
External Ids for ADGRB2 Gene
- HGNC: 944
- Entrez Gene: 576
- Ensembl: ENSG00000121753
- OMIM: 602683
- UniProtKB: O60241
Previous HGNC Symbols for ADGRB2 Gene
- BAI2
Summaries for ADGRB2 Gene
-
This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for ADGRB2 Gene
ADGRB2 (Adhesion G Protein-Coupled Receptor B2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRB3.
UniProtKB/Swiss-Prot for ADGRB2 Gene
-
Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236). Involved in angiogenesis inhibition (By similarity).
Additional gene information for ADGRB2 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRB2 Gene
Genomics for ADGRB2 Gene
GeneHancer (GH) Regulatory Elements for ADGRB2 Gene
Promoters and enhancers for ADGRB2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ADGRB2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ADGRB2 Gene
Genomic Locations for ADGRB2 Gene
- chr1:31,727,105-31,764,893
- (GRCh38/hg38)
- Size:
- 37,789 bases
- Orientation:
- Minus strand
- chr1:32,192,718-32,230,494
- (GRCh37/hg19)
Genomic View for ADGRB2 Gene
Genes around ADGRB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p35.2 by Ensembl
- 1p35.2 by Entrez Gene
- 1p35.2 by HGNC
ADGRB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADGRB2 Gene
Proteins for ADGRB2 Gene
-
Protein details for ADGRB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60241-AGRB2_HUMAN
- Recommended name:
- Adhesion G protein-coupled receptor B2
- Protein Accession:
- O60241
- B9EGK9
- Q5T6K0
- Q8NGW8
- Q96GZ9
Protein attributes for ADGRB2 Gene
- Size:
- 1585 amino acids
- Molecular mass:
- 172656 Da
- Quaternary structure:
-
- Heterodimer of 2 chains generated by proteolytic processing; the large extracellular N-terminal fragment and the membrane-bound C-terminal fragment predominantly remain associated and non-covalently linked. Interacts with GABPB2 (By similarity). Interacts (via carboxy-terminus) with TAX1BP3 (PubMed:21787750). Interacts with GNAZ (PubMed:28891236). Interacts with SH3GL2 (PubMed:28891236).
- SequenceCaution:
-
- Sequence=BAA25362.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI16890.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for ADGRB2 Gene
Post-translational modifications for ADGRB2 Gene
- Autoproteolytic processes at the GPS domain; this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment.
- Glycosylated.
- Glycosylation at Asn106, Asn191, posLast=192192, posLast=356356, posLast=437437, Asn560, posLast=645645, and Asn867
Other Protein References for ADGRB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam antibodies for ADGRB2
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-
Santa Cruz Biotechnology (SCBT) Antibodies for ADGRB2
Protein Products
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-
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- antibodies-online: Search results for available BAI2 related products ranked by validation data
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-
Abcam proteins for ADGRB2
Assay Products
- antibodies-online: Search results for available BAI2 related products ranked by validation data
No data available for DME Specific Peptides for ADGRB2 Gene
Domains & Families for ADGRB2 Gene
Gene Families for ADGRB2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted intracellular proteins
- Predicted membrane proteins
- Predicted secreted proteins
- Transporters
Protein Domains for ADGRB2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ADGRB2 Gene
Graphical View of Domain Structure for InterPro Entry
O60241UniProtKB/Swiss-Prot:
AGRB2_HUMAN :- Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
- Family:
-
- Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Function for ADGRB2 Gene
Molecular function for ADGRB2 Gene
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Receptor activity is regulated by proteolytic processing. The long N-terminal has a an inhibitory effect on the constitutive signaling activity. Removal of the N-terminal region induces an increase of the receptor activity.
- UniProtKB/Swiss-Prot Function:
- Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236). Involved in angiogenesis inhibition (By similarity).
Phenotypes From GWAS Catalog for ADGRB2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | IEA | -- |
| GO:0004930 | G-protein coupled receptor activity | IMP,TAS | 28891236 |
| GO:0005515 | protein binding | IPI | 28891236 |
Phenotypes for ADGRB2 Gene
- MGI mutant phenotypes for ADGRB2:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ADGRB2:
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-
-
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-
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miRNA for ADGRB2 Gene
- miRTarBase miRNAs that target ADGRB2
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Inhibitory RNA Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ADGRB2
-
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Horizon Cell Lines for ADGRB2
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADGRB2 Gene
Localization for ADGRB2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADGRB2 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 3 |
- Centrosome (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005813 | centrosome | IDA | -- |
| GO:0005886 | plasma membrane | IEA,IDA | 28891236 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | TAS,IEA | -- |
Pathways & Interactions for ADGRB2 Gene
No Data Available
Interacting Proteins for ADGRB2 Gene
Selected Interacting proteins:
O60241-AGRB2_HUMAN
ENSP00000362762
for ADGRB2 Gene via
MINT
STRING
IID
| Symbol | External ID(s) | Details |
|---|---|---|
| GABPA | ||
| GABPB1 | ||
| GABPB1-IT1 | ||
| SHANK1 | ||
| ARHGAP1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007166 | cell surface receptor signaling pathway | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS,IDA | 28891236 |
| GO:0007422 | peripheral nervous system development | IEA | -- |
| GO:0016525 | negative regulation of angiogenesis | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ADGRB2 Gene
Transcripts for ADGRB2 Gene
mRNA/cDNA for ADGRB2 Gene
- (20) REFSEQ mRNAs :
- (86) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
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-
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Inhibitory RNA Products
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Clone Products
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-
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ADGRB2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for ADGRB2 (BAI2)
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP8: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: |
| ExUns: | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 | ^ | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28a | · | 28b | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | · | 31c | ^ | 32 | ^ | 33 | ^ | 34a | · | 34b | ^ | 35a | · | 35b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: |
Expression for ADGRB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
- Intraembryonic Epiblast Cells Epiblast
This gene is overexpressed in Cerebrospinal fluid (57.4) and Vitreous humor (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ADGRB2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ADGRB2 Gene:
ADGRB2mRNA Expression by UniProt/SwissProt for ADGRB2 Gene:
O60241-AGRB2_HUMAN
Tissue specificity:
Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Evidence on tissue expression from TISSUES for ADGRB2 Gene
- Nervous system(4.9)
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-
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No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADGRB2 Gene
Orthologs for ADGRB2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BAI2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | BAI2 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | BAI2 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Bai2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Bai2 33 34 |
|
||
| Adgrb2 16 |
|
||||
| platypus (Ornithorhynchus anatinus) |
Mammalia | BAI2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| chicken (Gallus gallus) |
Aves | BAI2 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | bai2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | BAI2 34 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | unc-5 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | T21B6.3 34 |
|
ManyToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5741 34 |
|
ManyToMany |
- Species where no ortholog for ADGRB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ADGRB2 Gene
Variants for ADGRB2 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs778361520 | likely-pathogenic, Progressive spastic paraparesis | 31,728,621(-) | G/A | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1000245649 | -- | 31,730,894(-) | G/A | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000296450 | -- | 31,730,637(-) | A/G | downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant | |
| rs1000296809 | -- | 31,743,057(-) | C/G/T | intron_variant | |
| rs1000351829 | -- | 31,731,497(-) | G/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758930 | CNV | loss | 17122850 |
| nsv1007390 | CNV | gain | 25217958 |
| nsv1007786 | CNV | gain | 25217958 |
| nsv1121760 | CNV | deletion | 24896259 |
| nsv461028 | CNV | loss | 19166990 |
| nsv545953 | CNV | loss | 21841781 |
| nsv950385 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
5.68% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.77;
66.68% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ADGRB2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADGRB2 Gene
Disorders for ADGRB2 Gene
Additional Disease Information for ADGRB2
No disorders were found for ADGRB2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADGRB2 Gene
Publications for ADGRB2 Gene
- Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). (PMID: 9533023) Shiratsuchi T … Tokino T (Cytogenetics and cell genetics 1997) 2 3 4 22 58
- International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. (PMID: 25713288) Hamann J … Schiöth HB (Pharmacological reviews 2015) 2 3 4 58
- A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity. (PMID: 28891236) Purcell RH … Hall RA (Human mutation 2017) 3 4 58
- Identification of brain-specific angiogenesis inhibitor 2 as an interaction partner of glutaminase interacting protein. (PMID: 21787750) Zencir S … Mohanty S (Biochemical and biophysical research communications 2011) 3 4 58
- Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing. (PMID: 20367554) Okajima D … Yokota H (Journal of receptor and signal transduction research 2010) 3 4 58
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- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ADGRB2
- Novus Biologicals proteins for ADGRB2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for ADGRB2
- Abcam proteins for ADGRB2
- Find your target
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- Browse Antibodies at Cloud-Clone Corp.
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- Browse Assay Kits at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ADGRB2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADGRB2
- VectorBuilder custom plasmid, inducible vectors for ADGRB2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADGRB2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 55 available BAI2 Antibodies ranked by validation data
- Compare Top BAI2 Antibodies
- antibodies-online: Search results for available BAI2 related products ranked by validation data
- antibodies-online: Search results for available BAI2 related products ranked by validation data
- GeneTex ADGRB2 antibody for ADGRB2
- Search GeneTex for Proteins for ADGRB2
- ViGene Biosciences adenoviral particle packaged cDNA for ADGRB2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ADGRB2 gene
- Search ViGene Biosciences for ADGRB2
- Santa Cruz Biotechnology (SCBT) Antibodies for ADGRB2
- Search Santa Cruz Biotechnology (SCBT) for ADGRB2 siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for ADGRB2 CRISPR
- Horizon Cell Lines for ADGRB2
- genomics-online: cdna clones - Search results for 87 available BAI2 gene related products
- Overview of 87 available BAI2 gene related products
- orf clones - Search results for 87 available BAI2 gene related products
- Overview of 87 available BAI2 gene related products
- genomics-online: gRNA clones - Search results for 87 available BAI2 gene related products
- Overview of 87 available BAI2 gene related products
- genomics-online: primer clones - Search results for 87 available BAI2 gene related products
- Overview of 87 available BAI2 gene related products
- genomics-online: shRNA clones - Search results for 87 available BAI2 gene related products
- Overview of 87 available BAI2 gene related products
Sources for ADGRB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew