Aliases for ADGRB1 Gene
Aliases for ADGRB1 Gene
External Ids for ADGRB1 Gene
- HGNC: 943
- Entrez Gene: 575
- Ensembl: ENSG00000181790
- OMIM: 602682
- UniProtKB: O14514
Previous HGNC Symbols for ADGRB1 Gene
- BAI1
Summaries for ADGRB1 Gene
-
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
GeneCards Summary for ADGRB1 Gene
ADGRB1 (Adhesion G Protein-Coupled Receptor B1) is a Protein Coding gene. Diseases associated with ADGRB1 include Glioblastoma. Among its related pathways are p53 Signaling and p53 Pathway (RnD). GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRB3.
UniProtKB/Swiss-Prot for ADGRB1 Gene
-
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADGRB1 Gene
Genomics for ADGRB1 Gene
Regulatory Elements for ADGRB1 Gene
Enhancers for ADGRB1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH08G142382 | 1.2 | Ensembl ENCODE | 14.6 | -66.3 | -66346 | 2.2 | MLX ZFP64 ARID4B SIN3A ZNF48 TCF12 SLC30A9 ZNF143 SP5 MXD4 | TSNARE1 ADGRB1 ZNF696 LOC100133669 GC08P142321 |
| GH08G142950 | 1.4 | FANTOM5 ENCODE dbSUPER | 11.7 | +502.2 | 502192 | 3.0 | TFAP4 CBX3 JUN TSC22D4 SIN3A YBX1 RARA FOSL1 ZNF791 FOS | ZNF623 ADGRB1 ENSG00000261710 LYNX1 LOC105375794 CDC42P3 |
| GH08G142234 | 0.8 | ENCODE | 16.5 | -214.0 | -214033 | 2.0 | CTCF TAF1 JUN MAX RAD21 ZIC2 FOSL1 SMC3 FOSL2 FOS | ADGRB1 LOC100133669 RN7SL260P GC08M142249 LINC00051 |
| GH08G142322 | 0.7 | FANTOM5 | 13.4 | -126.5 | -126503 | 0.4 | BCOR SMARCA5 ZBTB2 ARNT ZNF366 MTA1 ZNF512 NBN ZNF24 PRDM1 | ADGRB1 TSNARE1 GC08P142321 |
| GH08G142325 | 0.9 | ENCODE | 10.3 | -123.1 | -123100 | 2.5 | HDGF PKNOX1 CREB3L1 RB1 NFXL1 RARA ZNF335 EGR1 ZNF143 ZNF207 | TSNARE1 ADGRB1 ENSG00000261693 GC08P142321 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ADGRB1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ADGRB1 Gene
- Chromosome:
- 8
- Start:
- 142,449,430 bp from pter
- End:
- 142,545,009 bp from pter
- Size:
- 95,580 bases
- Orientation:
- Plus strand
Genomic View for ADGRB1 Gene
Genes around ADGRB1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.3 by Ensembl
- 8q24.3 by Entrez Gene
- 8q24.3 by HGNC
ADGRB1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADGRB1 Gene
Proteins for ADGRB1 Gene
-
Protein details for ADGRB1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O14514-BAI1_HUMAN
- Recommended name:
- Brain-specific angiogenesis inhibitor 1
- Protein Accession:
- O14514
Protein attributes for ADGRB1 Gene
- Size:
- 1584 amino acids
- Molecular mass:
- 173501 Da
- Quaternary structure:
-
- Interacts with ELMO1 and DOCK1. When bound to ELMO1 and DOCK1, it may act as a module to promote the engulfment (By similarity). Interacts with MAGI1, MAGI3, BAIAP2 and PHYHIP.
Protein Expression for ADGRB1 Gene
Post-translational modifications for ADGRB1 Gene
- The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ADGRB1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for ADGRB1 (BAI1)
-
Custom Antibody ServicesOriGene Antibodies for ADGRB1
- Novus Biologicals Antibodies for ADGRB1
- Invitrogen Antibodies for ADGRB1
- antibodies-online Antibodies for ADGRB1: See all 86
- GeneTex ADGRB1 antibody for ADGRB1
Protein Products
- R&D Systems Proteins and Enzymes for ADGRB1 (BAI1)
-
OriGene Purified Proteins for ADGRB1
- Search Origene for MassSpec and Protein Over-expression Lysates for ADGRB1
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- Search GeneTex for Proteins for ADGRB1
Assay Products
- antibodies-online Kits for ADGRB1: See all 2
No data available for DME Specific Peptides for ADGRB1 Gene
Domains & Families for ADGRB1 Gene
Gene Families for ADGRB1 Gene
Protein Domains for ADGRB1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ADGRB1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O14514UniProtKB/Swiss-Prot:
BAI1_HUMAN :- The TSP1 repeats inhibit in vivo angiogenesis in rat cornea induced by BFGF.
- Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
- Domain:
-
- The TSP1 repeats inhibit in vivo angiogenesis in rat cornea induced by BFGF.
- Family:
-
- Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Function for ADGRB1 Gene
Molecular function for ADGRB1 Gene
- UniProtKB/Swiss-Prot Function:
- Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.
- UniProtKB/Swiss-Prot Induction:
- By p53/TP53.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | IEA | -- |
| GO:0004930 | G-protein coupled receptor activity | IDA,IEA | 23782696 |
Phenotypes for ADGRB1 Gene
- MGI mutant phenotypes for ADGRB1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ADGRB1:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Dynamic nuclei (hole, folded or small irregular)
- Increased transferrin (TF) endocytosis
- Synthetic lethal with MLN4924 (a NAE inhibitor)
Animal Models for ADGRB1 Gene
- MGI Knock Outs for ADGRB1:
-
- Adgrb1 tm2a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ADGRB1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ADGRB1 gene
- Search ViGene Biosciences for ADGRB1
CRISPR Products
-
OriGene CRISPR knockouts for ADGRB1
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miRNA Products
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Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ADGRB1
- Browse OriGene Inhibitory RNA Products For ADGRB1
-
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Clone Products
-
OriGene ORF clones in human for ADGRB1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- VectorBuilder custom plasmid, inducible vectors for ADGRB1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADGRB1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for ADGRB1 (BAI1)
Cell Line Products
-
Horizon Cell Lines for ADGRB1
-
ViGene Biosciences adenoviral particle packaged cDNA for ADGRB1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ADGRB1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ADGRB1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ADGRB1 Gene
Localization for ADGRB1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADGRB1 Gene
- Cell membrane; Multi-pass membrane protein. Note=Likely to be concentrated at cell-cell adhesion sites.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 1 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA,TAS | 9647739 |
| GO:0005887 | integral component of plasma membrane | TAS | 9647739 |
| GO:0005911 | cell-cell junction | TAS | 9647739 |
| GO:0014069 | postsynaptic density | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for ADGRB1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | DNA Damage Response | ||
| 2 | p53 Pathway (RnD) | ||
| 3 | p53 Signaling |
.44
|
|
Pathways by source for ADGRB1 Gene
1 KEGG pathway for ADGRB1 Gene
1 R&D Systems pathway for ADGRB1 Gene
1 Qiagen pathway for ADGRB1 Gene
Interacting Proteins for ADGRB1 Gene
Selected Interacting proteins:
O14514-BAI1_HUMAN
ENSP00000313046
for ADGRB1 Gene via
MINT
STRING
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007165 | signal transduction | TAS,IEA | 9647739 |
| GO:0007166 | cell surface receptor signaling pathway | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
| GO:0007409 | axonogenesis | TAS | 10343108 |
No data available for SIGNOR curated interactions for ADGRB1 Gene
Drugs & Compounds for ADGRB1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| PHOSPHATIDYLSERINE | Pharma | 0 |
Transcripts for ADGRB1 Gene
mRNA/cDNA for ADGRB1 Gene
- (10) REFSEQ mRNAs :
- (32) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for ADGRB1
- GenScript: Design CRISPR guide RNA sequences for ADGRB1
miRNA Products
- Search ViGene Biosciences for ADGRB1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ADGRB1
- Browse OriGene Inhibitory RNA Products For ADGRB1
-
ViGene Biosciences ready-to-package AAV shRNAs for ADGRB1 gene
Clone Products
-
OriGene ORF clones in human for ADGRB1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ADGRB1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADGRB1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for ADGRB1 (BAI1)
Flow Cytometry Products
Expression for ADGRB1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Hair (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
-
Dermis (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
This gene is overexpressed in Fetal Brain (68.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ADGRB1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ADGRB1 Gene:
ADGRB1mRNA Expression by UniProt/SwissProt for ADGRB1 Gene:
O14514-BAI1_HUMAN
Tissue specificity:
Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes.
Evidence on tissue expression from TISSUES for ADGRB1 Gene
- Nervous system(4.5)
Primer Products
-
OriGene qPCR primer pairs for ADGRB1
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADGRB1 Gene
Orthologs for ADGRB1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BAI1 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | BAI1 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | BAI1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Bai1 34 35 |
|
||
| Adgrb1 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Bai1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | BAI1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | BAI1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | BAI1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | bai1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | bai1a 35 |
|
OneToMany | |
| BAI1 (1 of 3) 35 |
|
OneToMany | |||
| bai1b 35 |
|
OneToMany | |||
| Dr.15237 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | unc-5 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | C36B7.5 35 |
|
ManyToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany |
- Species where no ortholog for ADGRB1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ADGRB1 Gene
Variants for ADGRB1 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000032621 | -- | 142,506,458(+) | GAGCA(A/G)GTGTA | intron-variant | |
| rs1000036960 | -- | 142,526,324(+) | GGTGC(C/G)GGTGA | intron-variant | |
| rs1000047385 | -- | 142,491,235(+) | TTCAG(A/G)CTCAT | intron-variant | |
| rs1000061678 | -- | 142,478,528(+) | AGCAT(A/G)GGGTG | intron-variant | |
| rs1000073848 | -- | 142,515,236(+) | GGCCG(C/T)GCTGT | intron-variant |
Residual Variation Intolerance Score:
3.73% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.30;
41.06% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ADGRB1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ADGRB1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADGRB1 Gene
Disorders for ADGRB1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glioblastoma |
|
Search ADGRB1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ADGRB1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ADGRB1
No data available for UniProtKB/Swiss-Prot and Genatlas for ADGRB1 Gene
Publications for ADGRB1 Gene
- Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. (PMID: 12507886) Kaur B. … Van Meir E.G. (Am. J. Pathol. 2003) 3 4 22 64
- Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. (PMID: 10343108) Oda K. … Tokino T. (Cytogenet. Cell Genet. 1999) 3 4 22 64
- Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1. (PMID: 9647739) Shiratsuchi T. … Tokino T. (Biochem. Biophys. Res. Commun. 1998) 3 4 22 64
- Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). (PMID: 9533023) Shiratsuchi T. … Tokino T. (Cytogenet. Cell Genet. 1997) 2 3 22 64
- International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. (PMID: 25713288) Hamann J. … SchiAPth H.B. (Pharmacol. Rev. 2015) 2 3 64
Products for ADGRB1 Gene
- R&D Systems Antibodies for ADGRB1 (BAI1)
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- Novus Biologicals Antibodies for ADGRB1
- Novus Biologicals proteins and lysates for ADGRB1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for ADGRB1: See all 86
- antibodies-online Kits for ADGRB1: See all 2
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex ADGRB1 antibody for ADGRB1
- Search GeneTex for Proteins for ADGRB1
- ViGene Biosciences adenoviral particle packaged cDNA for ADGRB1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ADGRB1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ADGRB1 gene
- Search ViGene Biosciences for ADGRB1
- Horizon Cell Lines for ADGRB1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADGRB1
- VectorBuilder custom plasmid, inducible vectors for ADGRB1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADGRB1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ADGRB1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
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