ADD3 Gene
protein-coding GIFtS: 59
GCID: GC10P111755
|
|
adducin 3 (gamma)
(Previous symbol: ADDL)
| |
Aliases
for ADD3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adducin 3 (Gamma)1 2 | | ADDL1 2 3 5 | | Adducin-Like Protein 702 3 | | Gamma-Adducin1 |
Export aliases for ADD3 gene to outside databasesPrevious GC identifers: GC10P110658 GC10P111094 GC10P111897 GC10P111430 GC10P111432 GC10P105396 |
Summaries
for ADD3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ADD3:
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. Thethree subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in theassembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Whileadducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain andhematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducinsalpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated withthe regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gammasubunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminalregion is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. Thelatter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is requiredfor association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoformshave been described. The functions of the different isoforms are not known. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ADDG_HUMAN, Q9UEY8Function: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds tocalmodulin
Gene Wiki entry for ADD3
|
Genomic Views
for ADD3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ADD3 gene promoter:
Oct-B1 oct-B2 POU2F1 oct-B3 POU2F1a Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for ADD3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADD3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q25.2 Ensembl cytogenetic band: 10q25.1 HGNC cytogenetic band: 10q25.2ADD3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P111755: view genomic region
(about GC identifiers)
Start:
|
111,756,126 bp from pter |
End:
|
111,895,323 bp from pter |
Size:
|
139,198 bases |
Orientation:
|
plus strand |
|
Proteins
for ADD3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ADDG_HUMAN, Q9UEY8 (See
protein sequence)Recommended Name: Gamma-adducin Size: 706 amino acids; 79155 Da
Subunit: Heterodimer of an alpha and a gamma subunit
Subcellular location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side
Secondary accessions: D3DRA8 O43243 Q5VU09 Q92773 Q9UEY7Alternative splicing: 2 isoforms: Q9UEY8-1 Q9UEY8-2 Explore the universe of human proteins at neXtProt for ADD3: NX_Q9UEY8
Post-translational modifications:
Sumoylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UEY8
ADD3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001112.2 NP_058432.1 NP_063968.1
ENSEMBL proteins: ENSP00000353286 ENSP00000348381 ENSP00000277900
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ADD3 for ontologies About GeneDecksing
ADD3 Antibody Products:
Assay Products for ADD3: |
Protein
Domains /
Families
for ADD3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ADD3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9UEY8ProtoNet protein and cluster: Q9UEY8 1 Blocks protein family: IPB001303 Class II aldolase/adducin
UniProtKB/Swiss-Prot: ADDG_HUMAN, Q9UEY8Domain: Comprised of three regions: a N-terminal protease-resistant globular head region, a short connecting subdomain,and a protease-sensitive tail regionSimilarity: Belongs to the aldolase class II family. Adducin subfamily |
Function
for ADD3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ADDG_HUMAN, Q9UEY8Function: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds tocalmodulin Genatlas biochemistry entry for ADD3:adducin 3,actin accessory protein,calmodulin binding,ubiquitously expressed
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ADD3 (NM_016824) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADD3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADD3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADD3 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
ADD3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ADD3:
Animal Models:
Mouse knock-out Add3tm1.2Llp for ADD3
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Add3):
ADD3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ADD3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of cAMP-Dependent PKA | |
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ADD3
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADD3
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for ADD3 (Q9UEY83 ENSP000003483814) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0042493 | response to drug |
-- | -- |
ADD3 for ontologies About GeneDecksing
|
Drugs & Compounds
for ADD3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ADD3
Search CenterWatch for drugs/clinical trials and news about ADD3 / ADDG
|
Transcripts
for ADD3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ADD3 gene (3 alternative transcripts): NM_001121.2 NM_016824.3 NM_019903.3 Unigene Cluster for ADD3: Adducin 3 (gamma) Hs.501012 [show with all ESTs]Unigene Representative Sequence: NM_01682418/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000468251 ENST00000360162 ENST00000356080 ENST00000277900(uc001kyt.4 uc001kys.4 uc001kyu.3 uc001kyv.3 uc001kyw.3 uc001kyx.3)
ENST00000480344 ENST00000484622 ENST00000487085 ENST00000459738 ENST00000495661
ENST00000497125 ENST00000475954 ENST00000496517 ENST00000468345 ENST00000473669
ENST00000486014 ENST00000462926 ENST00000488104 ENST00000488837
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ADD3 (NM_016824) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADD3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADD3 |
Additional cDNA sequence: AB209810.1 AK223270.1 AK291488.1 BC021694.1 BC043143.1 BC057285.1 BC062559.1 BX647403.1 BX647442.1 BX648016.1 D67031.1 EF553523.1 U37122.1 24/44 DOTS entries (see all 44): DT.100672560 DT.118663 DT.80101994 DT.95351696 DT.100678183 DT.95141368 DT.121244201 DT.95351635 DT.95142477 DT.86855570 DT.121244053 DT.75121299 DT.97803197 DT.97768609 DT.101985158 DT.95351634 DT.121244068 DT.95351701 DT.121244301 DT.95175555 DT.95351685 DT.92446183 DT.95351636 DT.121244085 24/565 AceView cDNA sequences (see all 565): BQ188069 AA516373 BM021347 AU134494 BX647442 BM021100 BQ892959 BQ267732 N22570 BM875698 CB156165 BQ272340 AW264722 AI333242 AI311524 H88934 AW169096 AA319783 NM_016824 BQ575308 AI200096 BQ006529 AI279403 BG618588
GeneLoc Exon Structure
5/25 Alternative Splicing Database (ASD) splice patterns (SP) for ADD3 (see all 25) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | · | 14c | · |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14d | · | 14e | · | 14f | ^ | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | · | 16c | · | 16d | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25a | · | 25b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ADD3
|
Expression
for ADD3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ADD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAAAAATTA
About this image
See ADD3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ADD3
SOURCE GeneReport for Unigene cluster: Hs.501012
UniProtKB/Swiss-Prot: ADDG_HUMAN, Q9UEY8Tissue specificity: Isoform 1 is ubiquitously expressed
SABiosciences Custom PCR Arrays for ADD3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADD3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ADD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADD3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADD3 |
Orthologs
for ADD3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ADD3 gene from 7/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Add31 , 5 |
adducin 3 (gamma)1, 5 |
86.92(n)1
92.21(a)1 |
|
19 (47.18 cM)5
273601 NM_001164099.11 NP_001157571.11
531404455 |
chicken
(Gallus gallus) |
Aves |
ADD31 |
adducin 3 (gamma) |
79.31(n)
85.94(a) |
|
373892 NM_204103.1 NP_989434.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ADD36 |
-- |
83(a) |
1 ↔ 1 |
3(44946388-44977299) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.59192 |
Transcribed sequence with moderate similarity to protein more |
74.72(n) |
|
BX727175.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc16e062 |
wufc16e06 |
73.3(n) |
|
324001 BC045384.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
hts3 |
ring canal formation, actin assembly actin
binding |
36(a) |
|
56D3 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
add-23 |
adducin |
45(a) |
|
V(12012251-12016002) -- |
ENSEMBL Gene Tree for ADD3 (if available)
TreeFam Gene Tree for ADD3 (if available) |
Paralogs
for ADD3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ADD3 gene
- ADD12 ADD22
2 SIMAP similar genes for ADD3 using alignment to 2 protein entries: ADDG_HUMAN (see all proteins):ADD2 ADD1
ADD3 for paralogs About GeneDecksing
|
Genomic Variants
for ADD3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ADD3 (111756126 - 111895323 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ADD3
1 CNV: 101043 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADD3 |
|
Disorders
/ Diseases
for ADD3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ADD3 for disorders About GeneDecksing
OMIM gene information: 601568
OMIM disorders: --
20/22  diseases for ADD3 (see all 22): About MalaCardstwin-to-twin transfusion syndrome twin twin transfusion syndrome hypertension endolymphatic hydrops
hereditary elliptocytosis elliptocytosis hereditary spherocytosis spherocytosis
dyscalculia biliary atresia twinning acute lymphoblastic leukemia
lymphoblastic leukemia diffuse astrocytoma essential hypertension was-related disorders
astrocytoma alzheimer's disease leukemia lung cancer
1 disease from the University of Copenhagen DISEASES database for ADD3:Dyscalculia Genetic Association Database (GAD): ADD3
Human Genome Epidemiology (HuGE) Navigator: ADD3 (11 documents)
Export disorders for ADD3 gene to outside databases
|
Publications
for ADD3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ADD3 gene, integrated from 9 sources (see all 52):
(articles sorted by number of sources associating them with ADD3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin. (PubMed id 8893809)1, 2, 3, 9 Katagiri T.... Hirai Y. (1996)
- Role of the adducin family genes in human essential hypertension. (PubMed id 15716695)1, 4, 9 Lanzani C....Manunta P. (2005)
- Epistatic interaction between alpha- and gamma-adducin influences peripheral and central pulse pressures in white Europeans. (PubMed id 15834281)1, 4, 9 Cwynar M....Bianchi G. (2005)
- Genomic organization of the human gamma adducin gene. (PubMed id 10581174)1, 2, 9 Citterio L.... Bianchi G. (1999)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates. (PubMed id 15561718)1, 2 Gocke C.B.... Kang J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2. (PubMed id 15963851)1, 9 Yenerel M.N....Gilligan D.M. (2005)
- Arterial properties in relation to genetic variations in the adducin subunits in a white population. (PubMed id 18787518)1, 9 Seidlerova J....Bianchi G. (2009)
- Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population. (PubMed id 18475162)1, 9 Kuznetsova T....Staessen J.A. (2008)
|
External Searches for ADD3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ADD3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ADD3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ADD3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ADD3 gene:
Search GeneIP for patents involving ADD3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ADD3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ADD3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADD3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADD3 | | | OriGene Protein Over-expression Lysate for ADD3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ADD3 | | OriGene 3'-UTR Clone for ADD3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADD3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ADD3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ADD3 | | OriGene Custom Protein Services for ADD3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADD3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADD3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADD3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADD3 |
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| | | | Search Tocris compounds for ADD3 |
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 | | | ADD3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADD3 |
|  |  |  | | | | Search ThermoFisher Antibodies for ADD3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADD3 |
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