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ADCYAP1R1 Gene

protein-coding GIFtS: 65

GC07P031058

adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
OTTHUMP00000025502 ^²
OTTHUMP00000123435 ^²
PAC1 ^²
PACAP-R-1 ^³
PACAPR ^¹, ², ⁵
PACAPRI ^²

Descriptions
PACAP type I receptor ^³
adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1 ^²
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I ^²
pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop ^²

External Ids
HGNC: 242¹
Entrez Gene: 117²
UniProtKB: P41586³
Ensembl: ENSG00000078549⁷

Search outside databases for aliases for ADCYAP1R1 gene

Previous GC identifers: GC07P030734 GC07P030834 GC07P030865

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ADCYAP1R1:

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a

membrane-associated protein and shares significant homology with members of the glucagon/secretin

receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating

polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of

this gene generates four major splice variants, but their full-length nature has not been

determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: PACR_HUMAN, P41586

Function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated

by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin,

luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in

spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the

gastrointestinal tract

Gene Wiki entry for ADCYAP1R1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ADCYAP1R1 gene

Entrez Gene cytogenetic band: 7p14 Ensembl cytogenetic band: 7p15.1 HGNC chromosome: 7

ADCYAP1R1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P031058: (about GC identifiers)

Start:	31,058,650 bp from pter
End:	31,113,403 bp from pter
Size:	54,754 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 31,141,320-31,195,489

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: PACR_HUMAN, P41586 (See protein sequence)

Recommended Name: Pituitary adenylate cyclase-activating polypeptide type I receptor precursor

Size: 468 amino acids; 53314 Da

Subcellular location: Cell membrane; Multi-pass membrane protein

PDB structures from and Proteopedia :

2JOD (3D)

REFSEQ proteins: NP_001109.2

ENSEMBL proteins:

ENSP00000371083 ENSP00000371081 ENSP00000371082 ENSP00000387335 ENSP00000379514 ENSP00000386395

ENSP00000306620

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant ADCYAP1R1 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (PACAP receptor)
	Human Recombinant Proteins from Abnova (ADCYAP1R1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	7902709
GO:0005887	integral to plasma membrane	TAS	7902709

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Antibodies for ADCYAP1R1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of ADCYAP1R1
	Sigma-Aldrich Antibodies for ADCYAP1R1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (PACAP receptor), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ADCYAP1R1)
	Novus Biologicals Antibody for ADCYAP1R1

Assays for ADCYAP1R1:

	Invitrogen Assays for ADCYAP1R1
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P41586

ProtoNet protein and cluster: P41586

2 Blocks protein families:

IPB000832 G-protein coupled receptors family 2 (secretin-like)

IPB002285 Pituitary adenylate cyclase activating polypeptide type 1 receptor signature

UniProtKB/Swiss-Prot: PACR_HUMAN, P41586

Similarity: Belongs to the G-protein coupled receptor 2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADCYAP1R1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADCYAP1R1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001118

Applied Biosystems Silencer® siRNAs for ADCYAP1R1

Sigma-Aldrich siRNA and siRNA Panels for ADCYAP1R1

Sigma-Aldrich shRNA Panels and shRNA for ADCYAP1R1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Millipore Clones for the Expression of ADCYAP1R1

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001118
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001118
untagged cDNA clone in CMV expression vector: NM_001118

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001118

UniProtKB/Swiss-Prot: PACR_HUMAN, P41586

Function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated

by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin,

luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in

spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the

gastrointestinal tract

Genatlas biochemistry entry for ADCYAP1R1:

pituitary adenylyl cyclase activating polypeptide receptor,with five splice variants among which

four also activating phospholipase C and a sixth variant (PACAPR-TM4) activating L-type Ca++

channels,expressed in islet beta cells and involved in the physiological control of insulin

release

8 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Adcyap1r1):

behavior/neurological	growth/size	homeostasis/metabolism	immune system	lethality-postnatal
nervous system	normal	reproductive system

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004999	vasoactive intestinal polypeptide receptor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ADCYAP1R1

5/10 Interacting proteins for ADCYAP1R1 (P41586² ENSP00000306620³) via UniProtKB, MINT, and/or STRING (see all 10 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CALM1	P62158²	MINT-51636
CALM2	P62158²	MINT-51636
CALM3	P62158²	MINT-51636
ADCYAP1	ENSP00000269200³	STRING (score=.996)
VIP	ENSP00000356213³	STRING (score=.98)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	EXP	16939974
GO:0007186	G-protein coupled receptor protein signaling pathway	IEA	--
GO:0007190	activation of adenylate cyclase activity	EXP	16805430
GO:0007275	multicellular organismal development	IEA	--
GO:0007283	spermatogenesis	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for ADCYAP1R1

Browse Small Molecules at Sigma-Aldrich

Compounds for ADCYAP1R1 available from Tocris Bioscience

Compound	Action	CAS number
PACAP 6-38	Potent PAC1 receptor antagonist	[143748-18-9]
PACAP 1-38	Potent stimulator of adenylyl cyclase
PACAP 1-27	Potent stimulator of adenylyl cyclase	[137061-48-4]

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3 Novoseek chemical compound relationships for ADCYAP1R1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pacap 38	82.93	2	7623776 (2)
ribonucleic acid	37.84	1	10650947 (1)
calcium	0.00	2	11941395 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADCYAP1R1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADCYAP1R1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001118

Sigma-Aldrich siRNA and siRNA Panels for ADCYAP1R1

Sigma-Aldrich shRNA Panels and shRNA for ADCYAP1R1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001118

REFSEQ mRNAs for ADCYAP1R1 gene:

NM_001118.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001118

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001118
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001118
                                 untagged cDNA clone in CMV expression vector: NM_001118

Additional cDNA sequence:

AK096545.1 AK124304.1 AK226138.1 AK290046.1 AY366498.1 AY462278.1 AY462279.1 AY495951.1

AY495952.1 BC117116.1 BC136267.1 BC143679.1 BX538156.1

3 DOTS entries:

DT.412226 DT.40237818 DT.101983437

24/97 AceView cDNA sequences (see all 97 ):

BU501683 AW006247 AI655924 AY462278 AI419703 T33146 AK124304 N52753

BX488413 AW512246 AI094596 AY462279 BG056056 BQ071801 AL138253 F10388

AI815550 BF904755 AY366498 NM_001118 BQ935207 AA878453 AW451961 AI418971

highest scoring ESTs for ADCYAP1R1:

AA077171 AY366498 BF314839 D17516 AA077714 AA584807 AI815550 AW163769 BF946981 BQ069787

Unigene Cluster for ADCYAP1R1:

Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

Hs.377783 [show with all ESTs]

Unigene Representative Sequence: BX538156

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ADCYAP1R1 (see all 9 )

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16a	·	16b	·	16c	·	16d	^	17a	·	17b	^	18
SP1:																																			-		-
SP2:																																					-
SP3:
SP4:			-										-
SP5:

About this scheme

ECgene alternative splicing isoforms for ADCYAP1R1

7 Ensembl transcripts including schematic representations:

ENST00000381667 ENST00000381665 ENST00000381666 ENST00000409363 ENST00000396211 ENST00000409489

ENST00000304166

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ADCYAP1R1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ADCYAP1R1

¹ / ² / ³

6 probe-sets matching ADCYAP1R1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35568_at²^{, 3}	U95-A	1	1.00	1.00	0.04	0.60	D17516	0.80	1.00	0.91	1
45641_at*²^{, 3}	U95-B	1	1.00	1.00	0.93	1.41	AW006247	0.40	1.00	0.76	1
207151_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001118	0.60	1.00	0.82	1
226690_at*²^{, 3}	U133-B	1	1.00	1.00	--	--	AW451961	0.20	1.00	0.72	1
207151_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
226690_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTTCCTGCCT

SOURCE GeneReport for Unigene cluster: Hs.377783
Expression variation in blood from EXPOLDB for ADCYAP1R1
UniProtKB/Swiss-Prot: PACR_HUMAN, P41586
Tissue specificity: Most abundant in the brain, low expression in the lung, liver, thymus, spleen,
pancreas and placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ADCYAP1R1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ADCYAP1R1¹	--	adenylate cyclase activating polypeptide 1 (pituitary) more	90.01(n) 93.79(a)	482386 XM_539503.2 XP_539503.2
chimpanzee (Pan troglodytes)	ADCYAP1R1¹	--	adenylate cyclase activating polypeptide 1 (pituitary) more	99.57(n) 100(a)	472340 XM_001166622.1 XP_001166622.1
cow (Bos taurus)	ADCYAP1R1¹	--	adenylate cyclase activating polypeptide 1 (pituitary) more	90.88(n) 95.51(a)	319095 NM_175715.2 NP_783646.1
rat (Rattus norvegicus)	Adcyap1r1¹	--	adenylate cyclase activating polypeptide 1 (pituitary) more	88.08(n) 92.72(a)	24167 NM_133511.1 NP_598195.1
mouse (Mus musculus)	Adcyap1r1^{1, 5}	6⁵	adenylate cyclase activating polypeptide 1 receptor more^{1, 5}	88.25(n)¹ 92.74(a)¹	11517¹ NM_007407.3¹ NP_031433.3¹ AI843743⁵ AI846590⁵ (see all 22)

About this table Species with no ortholog for ADCYAP1R1

ENSEMBL Gene Tree for ADCYAP1R1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ADCYAP1R1 gene

VIPR1² GHRHR² VIPR2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/287 NCBI SNPs in ADCYAP1R1 are shown (see all 287 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 128)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2302476^1,2	A,C,F	31112980(+)	`ACTGGG/AATTGT`	1	--	ng3¹		1		EA	1482
	rs11984383^1,2	A,C	31058199(+)	`CAGAGA/TCAGAG`	1	--	ng5¹		0	--	--	--	--
--	rs7804302^1,2	A	31084171(+)	`AAGCCC/TGCCCA`	1	P/P	syn¹ ese³		0	--	--	--	--
	rs35661943^1,2	F	31112748(+)	`GGCACC/ACAGCT`	1	T/T	syn¹		1		NA	44
	rs1006622^1,2	A,C,F,H,O	31075421(-)	`CACAAC/TGCACA`	1	--	int¹		11		NA EA EU WA	1090
	rs2284225^1,2	A,C,F,H,O	31105028(+)	`CATCAA/GGTCCA`	1	--	int¹		13		EA NA EU WA	2544
	rs2267733^1,2	A,C,F,H,O	31101334(+)	`GTAAAC/TCACTG`	1	--	int¹		13		EA EU WA	2760
	rs2267729^1,2	A,C,F,H,O	31088991(+)	`CAGAGA/TTACCC`	1	--	int¹		12		EU EA WA NA	1036
	rs6970447^1,2	A,C,F,H	31068679(+)	`TCTGGG/AGCTAG`	1	--	int¹		8		EU EA WA	836
	rs12668955^1,2	A,C,F,H	31082693(+)	`TCTCAG/ATTCGT`	1	--	int¹		12		EU EA WA	1258

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HapMap Linkage Disequilibrium images for ADCYAP1R1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 102981

Human Genome Epidemiology Navigator: ADCYAP1R1 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/63 PubMed articles for ADCYAP1R1 gene (see all 63 ):

Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor. (PubMed id 7902709)^{1, 2, 3, 4} Ogi K.... Fujino M. (1993)
Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical and genetic map of chromosome 7. (PubMed id 7851900)^{1, 3, 4} Stoffel M.... Bell G.I. (1994)
Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP-receptor type 1 expression in rat and human placenta. (PubMed id 10698193)^{1, 3} Scaldaferri M.L....Moretti C. (2000)
Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)³ GratacA^s M....Carracedo A. (2008)
Novel stable PACAP analogs with potent activity towards the PAC1 receptor. (PubMed id 18353507)³ Bourgault S....Fournier A. (2008)
Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS. (PubMed id 17470806)³ Sun C....Olejniczak E.T. (2007)
Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in mice. (PubMed id 16823490)³ Lang B....Shen S. (2006)
Localization and characterization of pituitary adenylate cyclase-activating polypeptide receptors in the human cerebellum during development. (PubMed id 16572459)³ Basille M....Gonzalez B. (2006)
Neuroendocrine tumors express PAC1 receptors. (PubMed id 16888199)³ Lieu S.N....Germano P.M. (2006)
PAC1-R null isoform expression in human prostate cancer tissue. (PubMed id 16372333)³ Mammi C....Moretti C. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 117	HGNC: 242	AceView: ADCYAP1R1	Ensembl:ENSG00000078549	euGenes: HUgn117
ECgene: ADCYAP1R1	H-InvDB: ADCYAP1R1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for ADCYAP1R1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ADCYAP1R1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ADCYAP1R1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ADCYAP1R1		Antibodies for ADCYAP1R1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ADCYAP1R1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ADCYAP1R1)
	Antibodies (ADCYAP1R1)
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	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (PACAP receptor)
	Antibodies (PACAP receptor)

Search OriGene for ADCYAP1R1

Tocris compounds for ADCYAP1R1

	Drugs for ADCYAP1R1
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ADCYAP1R1

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ADCYAP1R1 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for ADCYAP1R1

Summaries
for ADCYAP1R1

Genomic Location
for ADCYAP1R1

Proteins
for ADCYAP1R1

Protein Domains/
Families
for ADCYAP1R1

Gene Function
for ADCYAP1R1

Pathways & Interactions
for ADCYAP1R1

Drugs & Compounds
for ADCYAP1R1

Transcripts
for ADCYAP1R1

Expression
for ADCYAP1R1

Orthologs
for ADCYAP1R1

Paralogs
for ADCYAP1R1

SNPs/Variants
for ADCYAP1R1

Disorders & Mutations
for ADCYAP1R1

Medical News
for ADCYAP1R1

Publications
for ADCYAP1R1

Search for ADCYAP1R1

Genome Databases showing ADCYAP1R1

Other Databases showing ADCYAP1R1

Specialized Databases showing ADCYAP1R1

Licensable Technologies
for ADCYAP1R1

Services
for ADCYAP1R1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ADCYAP1R1 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor ADCYAP1R1

Summariesfor ADCYAP1R1

Genomic Locationfor ADCYAP1R1

Proteinsfor ADCYAP1R1

Protein Domains/Familiesfor ADCYAP1R1

Gene Functionfor ADCYAP1R1

Pathways & Interactionsfor ADCYAP1R1

Drugs & Compoundsfor ADCYAP1R1

Transcriptsfor ADCYAP1R1

Expression for ADCYAP1R1

Orthologsfor ADCYAP1R1

Paralogsfor ADCYAP1R1

SNPs/Variantsfor ADCYAP1R1

Disorders & Mutationsfor ADCYAP1R1

Medical Newsfor ADCYAP1R1

Publicationsfor ADCYAP1R1

Search for ADCYAP1R1

Genome Databases showing ADCYAP1R1

Other Databases showing ADCYAP1R1

Specialized Databases showing ADCYAP1R1

Licensable Technologiesfor ADCYAP1R1

Servicesfor ADCYAP1R1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ADCYAP1R1

Summaries
for ADCYAP1R1

Genomic Location
for ADCYAP1R1

Proteins
for ADCYAP1R1

Protein Domains/
Families
for ADCYAP1R1

Gene Function
for ADCYAP1R1

Pathways & Interactions
for ADCYAP1R1

Drugs & Compounds
for ADCYAP1R1

Transcripts
for ADCYAP1R1

Expression
for ADCYAP1R1

Orthologs
for ADCYAP1R1

Paralogs
for ADCYAP1R1

SNPs/Variants
for ADCYAP1R1

Disorders & Mutations
for ADCYAP1R1

Medical News
for ADCYAP1R1

Publications
for ADCYAP1R1

Licensable Technologies
for ADCYAP1R1

Services
for ADCYAP1R1