V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

ADCY9 Gene

protein-coding GIFtS: 68

GC16M003952

adenylate cyclase 9
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AC9 ^¹, ²
EC 4.6.1.1 ^³
KIAA0520 ^³

Descriptions
ATP pyrophosphate-lyase 9 ^³
Adenylate cyclase type IX ^³
Adenylyl cyclase 9 ^³
adenylate cyclase 9 ^²
type IX ATP pyrophosphate-lyase ^²

External Ids
HGNC: 240¹
Entrez Gene: 115²
UniProtKB: O60503³
Ensembl: ENSG00000162104⁷

Search outside databases for aliases for ADCY9 gene

Previous GC identifers: GC16M004044 GC16M004015

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ADCY9:

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP.

It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type

9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by

beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.

[provided by RefSeq]

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503

Function: May play a fundamental role in situations where fine interplay between intracellular

calcium and cAMP determines the cellular function. May be a physiologically relevant docking site

for calcineurin (By similarity)

Gene Wiki entry for ADCY9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ADCY9 gene

Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3

ADCY9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M003952: (about GC identifiers)

Start:	3,952,653 bp from pter
End:	4,106,187 bp from pter
Size:	153,535 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000016.8 NT_037887.4

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503 (See protein sequence)

Recommended Name: Adenylate cyclase type 9

Size: 1353 amino acids; 150701 Da

Cofactor: Binds 2 magnesium ions per subunit

Subcellular location: Membrane; Multi-pass membrane protein

Secondary accessions: O60273 Q4ZHT9 Q4ZIR5 Q9BWT4 Q9UGP2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001107.2

ENSEMBL proteins:

ENSP00000294016

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ADCY9)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	TAS	9628827
GO:0016020	membrane	IEA	--

About this table

Antibodies for ADCY9:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ADCY9), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for ADCY9

Assays for ADCY9:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O60503

ProtoNet protein and cluster: O60503

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503

Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family

Similarity: Contains 2 guanylate cyclase domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADCY9)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADCY9)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001116

Applied Biosystems Silencer® siRNAs for ADCY9

Sigma-Aldrich siRNA and siRNA Panels for ADCY9

Sigma-Aldrich shRNA for ADCY9

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ADCY9
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001116
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001116
untagged cDNA clone in CMV expression vector: NM_001116

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001116

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503

Function: May play a fundamental role in situations where fine interplay between intracellular

calcium and cAMP determines the cellular function. May be a physiologically relevant docking site

for calcineurin (By similarity)

Catalytic activity: ATP = 3',5'-cyclic AMP + diphosphate

Enzyme regulation: Insensitive to calcium/calmodulin, forskolin and somatostatin. Stimulated by

beta-adrenergic receptor activation

Enzyme Number (IUBMB): EC 4.6.1.1

Genatlas biochemistry entry for ADCY9:

adenylyl cyclase type IX,ubiquitously,with highest levels in skeletal muscle,heart and brain

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Adcy9):

immune system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0004016	adenylate cyclase activity	TAS	9628827

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/24 Sigma-Aldrich "Your Favorite Gene" Pathways for ADCY9 (Your Favorite Gene powered by Ingenuity) (see all 24 )

Endothelin-1 Signaling
Corticotropin Releasing Hormone Signaling
Synaptic Long Term Depression
Cardiac Hypertrophy Signaling
Antiproliferative Role of Somatostatin Receptor 2

GeneDecks ADCY9 for the pathways selected above

About GeneDecksing

5/99 Interacting proteins for ADCY9 (ENSP00000294016³) via UniProtKB, MINT, and/or STRING (see all 99 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GCG	ENSP00000364647³	STRING (score=.94)
CALM3	ENSP00000291295³	STRING (score=.936)
ADCY2	ENSP00000371971³	STRING (score=.926)
GNAS	ENSP00000302237³	STRING (score=.925)
PRKAR2B	ENSP00000265717³	STRING (score=.919)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006171	cAMP biosynthetic process	IEA	--
GO:0007242	intracellular signaling cascade	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for ADCY9

Sigma-Aldrich Small Molecules for ADCY9:

Inhibitor

Compounds for ADCY9 available from Tocris Bioscience

Compound	Action	CAS number
SQ 22536	Adenylyl cyclase inhibitor	[17318-31-9]
NKH 477	Water-soluble adenylyl cyclase activator	[138605-00-2]
PACAP 1-38	Potent stimulator of adenylyl cyclase
Forskolin	Adenylyl cyclase activator	[66575-29-9]
PACAP 1-27	Potent stimulator of adenylyl cyclase	[137061-48-4]

About this table

3 Novoseek chemical compound relationships for ADCY9 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
forskolin	60.31	4	9463474 (2), 11226046 (1)
cyclic amp	53.02	2	11226046 (1), 17551263 (1)
calcium	22.96	5	9822726 (1), 15794946 (1)

About this table

1 PharmGKB drug compound relationship for ADCY9 gene

Drug compound	PharmGKB Relations	PubMed IDs for articles supporting these relationships
isoproterenol	PD FA GN	12972952

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ADCY9)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ADCY9)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001116

Sigma-Aldrich siRNA and siRNA Panels for ADCY9

Sigma-Aldrich shRNA for ADCY9

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001116

REFSEQ mRNAs for ADCY9 gene:

NM_001116.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001116

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001116
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001116
                                 untagged cDNA clone in CMV expression vector: NM_001116

Additional cDNA sequence:

AB011092.3 AF036927.1 AJ133123.1 AK022108.1 BC068612.1 BC136657.1 BC136658.1 BC151207.1

BC151229.1 DQ005545.1 DQ008441.1

5 DOTS entries:

DT.455680 DT.97805016 DT.86849976 DT.75141941 DT.95266612

24/103 AceView cDNA sequences (see all 103 ):

AI572195 BE504143 BP350940 Z40718 AI583402 BQ424543 BF109524 BF475884

BM797762 CA772679 AU141090 T08314 AW470671 NM_001116 BF062146 AW014950

AU121046 AI075303 AU140135 CB995114 CB959938 AW963471 BE858662 AJ133123

highest scoring ESTs for ADCY9:

AB011092 AF036927 AJ133123 AA594693 AA694253 AA704471 AA778563 AI075303 AI093846 AI248827

Unigene Cluster for ADCY9:

Adenylate cyclase 9

Hs.391860 [show with all ESTs]

Unigene Representative Sequence: NM_001116

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ADCY9 (see all 6 )

ExUns:	1	^	2a	·	2b	·	2c	·	2d	^	3	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13
SP1:											-		-						-
SP2:																			-		-		-		-
SP3:											-		-						-
SP4:													-						-		-
SP5:											-		-

About this scheme

ECgene alternative splicing isoforms for ADCY9

1 Ensembl transcript including schematic representation:

ENST00000294016

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ADCY9 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ADCY9

¹ / ² / ³

7 probe-sets matching ADCY9 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33800_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF036927	0.80	1.00	0.91	1
204497_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AB011092	0.80	1.00	0.91	1
204498_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001116	0.60	1.00	0.82	1
215400_x_at*²^{, 3}	U133-A	5	1.00	0.93	--	--	AU146952	0.40	1.00	0.76	1
204497_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204498_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
215400_x_at*²	U133Plus2	5	1.00	0.93	--	--	--	--	--	--	--

GeneDecks ADCY9 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.391860
Expression variation in blood from EXPOLDB for ADCY9
UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503
Tissue specificity: Expressed in multiple cells of the lung, with expression highest in airway
smooth muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ADCY9 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ADCY9¹	--	adenylate cyclase 9	88.61(n) 92.97(a)	490031 XM_547151.2 XP_547151.2
chimpanzee (Pan troglodytes)	ADCY9¹	--	adenylate cyclase 9	97.88(n) 98(a)	453869 XM_510775.2 XP_510775.2
cow (Bos taurus)	ADCY9¹	--	adenylate cyclase 9	88.65(n) 91.41(a)	525482 XM_603835.3 XP_603835.3
mouse (Mus musculus)	Adcy9^{1, 5}	16 (2.00 cM)⁵	adenylate cyclase 9^{1, 5}	86.84(n)¹ 92.17(a)¹	11515¹ NM_009624.1¹ NP_033754.1¹ AA407393⁵ AK134627⁵ (see all 13)
chicken (Gallus gallus)	ADCY9¹	--	adenylate cyclase 9	77.64(n) 82.03(a)	395339 NM_204630.1 NP_989961.1

About this table Species with no ortholog for ADCY9

ENSEMBL Gene Tree for ADCY9

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ADCY9 gene

ADCY3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1089 NCBI SNPs in ADCY9 are shown (see all 1089 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 355)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs879620^1,2	A,C,F,H,O	3955730(-)	`ACACAG/ATAATA`	1	--	ut3¹ ese³		14		NA EA MN EU WA	1257
	rs2531995^1,2	A,C,F,H,O	3953468(-)	`CAGACG/ATTCTC`	1	--	ut3¹ ese³		4		EU EA WA	420
	rs2238434^1,2	A,C,F,H	3954270(+)	`AAAGAC/GTGGCT`	1	--	ut3¹		4		EU EA WA	406
	rs2230739^1,2	C,F,H,O	3973437(-)	`GTCATA/GAAGAA`	1	I/M	mis¹		13		MN EU EA WA NA	1086
	rs1045475^1,2	A,C,F,O	3955317(-)	`AGTGTC/TCCTCT`	1	--	ut3¹ ese³		1		MN	184
	rs2238435^1,2	A,C,O	3954283(+)	`AACTCC/GGACCG`	1	--	ut3¹ ese³		0	--	--	--	--
--	rs9927767^1,2	C,F,H	4108171(+)	`gggtcT/Atgaaa`	1	--	ng3¹		3		EU EA	300
	rs879619^1,2	C,F	3955047(+)	`CACACG/AGGCGT`	1	--	ut3¹ ese³		1		MN	184
	rs2238432^1,2	F,H	3954142(+)	`GATGGG/AGACTG`	1	--	ut3¹ ese³		5		EA EU WA	1898
	rs710893^1,2	A,C	3954965(-)	`GGAGGT/CGTTGG`	1	--	ut3¹ ese³		1		MN	184

About this table

HapMap Linkage Disequilibrium images for ADCY9 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603302

1 Novoseek disease relationship for ADCY9 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
asthma	11.03	1	15879435 (1)

About this table

1 PharmGKB disease relationship for ADCY9 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Asthma	PD FA GN	12972952

About this table

Human Gene Mutation Database: ADCY9
Genetic Association Database: ADCY9
Human Genome Epidemiology Navigator: ADCY9 (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/28 PubMed articles for ADCY9 gene (see all 28 ):

An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation. (PubMed id 12972952)^{1, 3, 4, 7} Small K.M....Liggett S.B. (2003)
Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9). (PubMed id 9628827)^{1, 2, 3, 4} Hacker B.M.... Storm D.R. (1998)
Molecular analysis, mutation screening, and association study of adenylate cyclase type 9 gene (ADCY9) in mood disorders. (PubMed id 11840511)^{1, 3, 6} Toyota T....Yoshikawa T. (2002)
Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. (PubMed id 15879435)^{1, 3, 4} Tantisira K.G.... Liggett S.B. (2005)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Association analysis of adenylate cyclase type 9 gene using pedigree disequilibrium test in bipolar disorder. (PubMed id 12082561)^{3, 6} Toyota T....Yoshikawa T. (2002)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{3, 4} Nakajima D.... Nagase T. (2002)
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)^{3, 4} Nagase T....Ohara O. (1998)
Identification and characterization of a widely expressed form of adenylyl cyclase. (PubMed id 8662814)^{1, 3} Premont R.T....Hanoune J. (1996)
Novel regulatory properties of human type 9 adenylate cyclase. (PubMed id 14996950)^{1, 3} Cumbay M.G. and Watts V.J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 115	HGNC: 240	AceView: ADCY9	Ensembl:ENSG00000162104	euGenes: HUgn115
ECgene: ADCY9	H-InvDB: ADCY9

(According to HUGE)
About This Section

HUGE: KIAA0520

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for ADCY9
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ADCY9:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ADCY9-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ADCY9		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ADCY9		Small molecules for ADCY9
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Chimera RNAi (ADCY9)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (ADCY9)
	Antibodies (ADCY9)

Search OriGene for ADCY9

Tocris compounds for ADCY9

	Drugs for ADCY9
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for ADCY9

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
ADCY9 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

ADCY9 Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for ADCY9

Summaries
for ADCY9

Genomic Location
for ADCY9

Proteins
for ADCY9

Protein Domains/
Families
for ADCY9

Gene Function
for ADCY9

Pathways & Interactions
for ADCY9

Drugs & Compounds
for ADCY9

Transcripts
for ADCY9

Expression
for ADCY9

Orthologs
for ADCY9

Paralogs
for ADCY9

SNPs/Variants
for ADCY9

Disorders & Mutations
for ADCY9

Medical News
for ADCY9

Publications
for ADCY9

Search for ADCY9

Genome Databases showing ADCY9

Other Databases showing ADCY9

Specialized Databases showing ADCY9

Licensable Technologies
for ADCY9

Services
for ADCY9

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ADCY9 Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor ADCY9

Summariesfor ADCY9

Genomic Locationfor ADCY9

Proteinsfor ADCY9

Protein Domains/Familiesfor ADCY9

Gene Functionfor ADCY9

Pathways & Interactionsfor ADCY9

Drugs & Compoundsfor ADCY9

Transcriptsfor ADCY9

Expression for ADCY9

Orthologsfor ADCY9

Paralogsfor ADCY9

SNPs/Variantsfor ADCY9

Disorders & Mutationsfor ADCY9

Medical Newsfor ADCY9

Publicationsfor ADCY9

Search for ADCY9

Genome Databases showing ADCY9

Other Databases showing ADCY9

Specialized Databases showing ADCY9

Licensable Technologiesfor ADCY9

Servicesfor ADCY9

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ADCY9

Summaries
for ADCY9

Genomic Location
for ADCY9

Proteins
for ADCY9

Protein Domains/
Families
for ADCY9

Gene Function
for ADCY9

Pathways & Interactions
for ADCY9

Drugs & Compounds
for ADCY9

Transcripts
for ADCY9

Expression
for ADCY9

Orthologs
for ADCY9

Paralogs
for ADCY9

SNPs/Variants
for ADCY9

Disorders & Mutations
for ADCY9

Medical News
for ADCY9

Publications
for ADCY9

Licensable Technologies
for ADCY9

Services
for ADCY9