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ADCY9 Gene

protein-coding   GIFtS: 68

GC16M003952
adenylate cyclase 9
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
AC9 1, 2
EC 4.6.1.1 3
KIAA0520 3
Descriptions
ATP pyrophosphate-lyase 9 3
Adenylate cyclase type IX 3
Adenylyl cyclase 9 3
adenylate cyclase 9 2
type IX ATP pyrophosphate-lyase 2
External Ids
HGNC: 2401
Entrez Gene: 1152
UniProtKB: O605033
Ensembl: ENSG000001621047
Search outside databases for aliases for ADCY9 gene

Previous GC identifers: GC16M004044 GC16M004015

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ADCY9:
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP.
It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type
9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by
beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.
[provided by RefSeq]

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503
Function: May play a fundamental role in situations where fine interplay between intracellular
calcium and cAMP determines the cellular function. May be a physiologically relevant docking site
for calcineurin (By similarity)

Gene Wiki entry for ADCY9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADCY9 gene  

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ADCY9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M003952:     (about GC identifiers)

Start:
3,952,653 bp from pter
End:
4,106,187 bp from pter
Size:
153,535 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000016.8  NT_037887.4  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503 (See protein sequence)
Recommended Name: Adenylate cyclase type 9  
Size: 1353 amino acids; 150701 Da
Cofactor: Binds 2 magnesium ions per subunit
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: O60273 Q4ZHT9 Q4ZIR5 Q9BWT4 Q9UGP2

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_001107.2  

    ENSEMBL proteins: 
    ENSP00000294016 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ADCY9)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887 integral to plasma membrane TAS9628827
    GO:0016020 membrane IEA--
    About this table

    Antibodies for ADCY9: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (ADCY9), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for ADCY9

    Assays for ADCY9: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    2 InterPro domains/families:
     IPR001054 A/G_cyclase
     IPR018297 A/G_cyclase_CS


       GeneDecks  ADCY9 for the domains selected above  
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    Graphical View of Domain Structure for InterPro Entry O60503

    ProtoNet protein and cluster: O60503

    UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503
    Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family
    Similarity: Contains 2 guanylate cyclase domains

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADCY9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADCY9)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001116

                  Applied Biosystems Silencer® siRNAs for ADCY9

                  Sigma-Aldrich siRNA and siRNA Panels for ADCY9  
                         Sigma-Aldrich shRNA for ADCY9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ADCY9
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001116
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001116
                                     untagged cDNA clone in CMV expression vector: NM_001116 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001116

    UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503
    Function: May play a fundamental role in situations where fine interplay between intracellular
    calcium and cAMP determines the cellular function. May be a physiologically relevant docking site
    for calcineurin (By similarity)
    Catalytic activity: ATP = 3',5'-cyclic AMP + diphosphate
    Enzyme regulation: Insensitive to calcium/calmodulin, forskolin and somatostatin. Stimulated by
    beta-adrenergic receptor activation
    Enzyme Number (IUBMB): EC 4.6.1.1 

    Genatlas biochemistry entry for ADCY9:
    adenylyl cyclase type IX,ubiquitously,with highest levels in skeletal muscle,heart and brain

    1 MGI mutant phenotype (inferred from 1 allele(MGI details for Adcy9):

    immune system

    2 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287 magnesium ion binding IEA--
    GO:0004016 adenylate cyclase activity TAS9628827
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    5/6 Invitrogen iPath™ Online BioAtlas - Pathways for ADCY9 (see all 6 ) (Maps provided by GeneGo):
     ATP metabolism
     cAMP signaling
     PKA signaling
     A2B Receptor: Action via G-alpha s. (map 2)
     Regulation of fatty acid metabolic enzymes FACL, ACADM, FASN and SCD via adenosin receptor activation

       GeneDecks  ADCY9 for the pathways selected above  
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    5/9 Millipore Pathways for ADCY9 (see all 9 )
     Adenylate cyclase-activating neuropeptides
     Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
     Development Beta-adrenergic receptors signaling via cAMP
     Signal transduction cAMP signaling
     Signal transduction PKA signaling

       GeneDecks  ADCY9 for the pathways selected above  
    About GeneDecksing

    5/24 Sigma-Aldrich "Your Favorite Gene" Pathways for  ADCY9  (Your Favorite Gene powered by Ingenuity) (see all 24
     Endothelin-1 Signaling
     Corticotropin Releasing Hormone Signaling
     Synaptic Long Term Depression
     Cardiac Hypertrophy Signaling
     Antiproliferative Role of Somatostatin Receptor 2

       GeneDecks  ADCY9 for the pathways selected above  
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    5/7 Kegg Pathways  (Kegg details for ADCY9) (see all 7 ):
     hsa00230 Purine metabolism
     hsa04020 Calcium signaling pathway
     hsa04270 Vascular smooth muscle contraction
     hsa04540 Gap junction
     hsa04912 GnRH signaling pathway

       GeneDecks  ADCY9 for the pathways selected above  
    About GeneDecksing

    5/99 Interacting proteins for ADCY9 (ENSP000002940163) via UniProtKB, MINT, and/or STRING (see all 99 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GCGENSP000003646473STRING (score=.94)
    CALM3ENSP000002912953STRING (score=.936)
    ADCY2ENSP000003719713STRING (score=.926)
    GNASENSP000003022373STRING (score=.925)
    PRKAR2BENSP000002657173STRING (score=.919)
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006171 cAMP biosynthetic process IEA--
    GO:0007242 intracellular signaling cascade IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for ADCY9
    Sigma-Aldrich Small Molecules for ADCY9:
    Inhibitor

    Compounds for ADCY9 available from Tocris Bioscience
    CompoundAction CAS number
    SQ 22536Adenylyl cyclase inhibitor[17318-31-9]
    NKH 477Water-soluble adenylyl cyclase activator[138605-00-2]
    PACAP 1-38Potent stimulator of adenylyl cyclase
    ForskolinAdenylyl cyclase activator[66575-29-9]
    PACAP 1-27Potent stimulator of adenylyl cyclase[137061-48-4]
    About this table


    3 Novoseek chemical compound relationships for ADCY9 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    forskolin 60.31 4 9463474 (2), 11226046 (1)
    cyclic amp 53.02 2 11226046 (1), 17551263 (1)
    calcium 22.96 5 9822726 (1), 15794946 (1)
    About this table

    1 PharmGKB drug compound relationship for ADCY9 gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    isoproterenolPD  FA  GN  12972952
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADCY9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADCY9)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001116

                  Sigma-Aldrich siRNA and siRNA Panels for ADCY9  
                         Sigma-Aldrich shRNA for ADCY9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001116  

    REFSEQ mRNAs for ADCY9 gene: 

    NM_001116.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001116  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001116
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001116
                                     untagged cDNA clone in CMV expression vector: NM_001116 

    Additional cDNA sequence: 

    AB011092.3 AF036927.1 AJ133123.1 AK022108.1 BC068612.1 BC136657.1 BC136658.1 BC151207.1 
    BC151229.1 DQ005545.1 DQ008441.1 

    5 DOTS entries:

    DT.455680  DT.97805016  DT.86849976  DT.75141941  DT.95266612 

    24/103 AceView cDNA sequences (see all 103 ):

    AI572195 BE504143 BP350940 Z40718 AI583402 BQ424543 BF109524 BF475884 
    BM797762 CA772679 AU141090 T08314 AW470671 NM_001116 BF062146 AW014950 
    AU121046 AI075303 AU140135 CB995114 CB959938 AW963471 BE858662 AJ133123 

    highest scoring ESTs for ADCY9:

    AB011092 AF036927 AJ133123 AA594693 AA694253 AA704471 AA778563 AI075303 AI093846 AI248827 

    Unigene Cluster for ADCY9:

    Adenylate cyclase 9
    Hs.391860  [show with all ESTs]
    Unigene Representative Sequence: NM_001116


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ADCY9 (see all 6 )

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                -     -                 -                                                               
    SP2:                                                        -     -     -     -                                             
    SP3:                                -     -                 -                                                               
    SP4:                                      -                 -     -                                                         
    SP5:                                -     -                                                                                 

    About this scheme

    ECgene alternative splicing isoforms for ADCY9

    1 Ensembl transcript including schematic representation:
    ENST00000294016  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADCY9 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADCY9

    1 / 2 / 3

    7 probe-sets matching ADCY9 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    33800_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AF036927 0.80 1.00 0.91 1

    204497_at2, 3 U133-A 1 1.00 1.00 -- -- AB011092 0.80 1.00 0.91 1

    204498_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001116 0.60 1.00 0.82 1

    215400_x_at*2, 3 U133-A 5 1.00 0.93 -- -- AU146952 0.40 1.00 0.76 1

    204497_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    204498_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    215400_x_at*2 U133Plus2 5 1.00 0.93 -- -- -- -- -- -- --
    GeneDecks  ADCY9 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.391860

    Expression variation in blood from EXPOLDB for ADCY9

    UniProtKB/Swiss-Prot: ADCY9_HUMAN, O60503
    Tissue specificity: Expressed in multiple cells of the lung, with expression highest in airway
    smooth muscle

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ADCY9 gene from 5/11 species (see all 11 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ADCY91   -- adenylate cyclase 9 88.61(n)
    92.97(a)
    490031  XM_547151.2  XP_547151.2 
    chimpanzee
    (Pan troglodytes)
    ADCY91   -- adenylate cyclase 9 97.88(n)
    98(a)
    453869  XM_510775.2  XP_510775.2 
    cow
    (Bos taurus)
    ADCY91   -- adenylate cyclase 9 88.65(n)
    91.41(a)
    525482  XM_603835.3  XP_603835.3 
    mouse
    (Mus musculus)
    Adcy91, 5 16 (2.00 cM)5
    adenylate cyclase 91, 5 86.84(n)1
    92.17(a)1
    115151  NM_009624.11  NP_033754.11 
     AA4073935  AK1346275  (see all 13)
    chicken
    (Gallus gallus)
    ADCY91   -- adenylate cyclase 9 77.64(n)
    82.03(a)
    395339  NM_204630.1  NP_989961.1 
    About this table        Species with no ortholog for ADCY9

    ENSEMBL Gene Tree for ADCY9
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADCY9 gene
    ADCY32  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/1089 NCBI SNPs in ADCY9 are shown (see all 1089 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 355)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 16 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs8796201,2
    A,C,F,H,O3955730(-) ACACAG/ATAATA 1 -- ut31 ese314Minor allele frequency- A:0.37NA EA MN EU WA 1257
    rs25319951,2
    A,C,F,H,O3953468(-) CAGACG/ATTCTC 1 -- ut31 ese34Minor allele frequency- A:0.35EU EA WA 420
    rs22384341,2
    A,C,F,H3954270(+) AAAGAC/GTGGCT 1 -- ut314Minor allele frequency- G:0.16EU EA WA 406
    rs22307391,2
    C,F,H,O3973437(-) GTCATA/GAAGAA 1 I/M mis113Minor allele frequency- G:0.34MN EU EA WA NA 1086
    rs10454751,2
    A,C,F,O3955317(-) AGTGTC/TCCTCT 1 -- ut31 ese31Minor allele frequency- T:0.15MN 184
    rs22384351,2
    A,C,O3954283(+) AACTCC/GGACCG 1 -- ut31 ese30--------
    --
    rs99277671,2
    C,F,H4108171(+) gggtcT/Atgaaa 1 -- ng313Minor allele frequency- A:0.03EU EA 300
    rs8796191,2
    C,F3955047(+) CACACG/AGGCGT 1 -- ut31 ese31Minor allele frequency- A:0.13MN 184
    rs22384321,2
    F,H3954142(+) GATGGG/AGACTG 1 -- ut31 ese35Minor allele frequency- A:0.20EA EU WA 1898
    rs7108931,2
    A,C3954965(-) GGAGGT/CGTTGG 1 -- ut31 ese31Minor allele frequency- C:0.00MN 184
    About this table

    HapMap Linkage Disequilibrium images for ADCY9 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 603302

    1 Novoseek disease relationship for ADCY9 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    asthma 11.03 1 15879435 (1)
    About this table

    1 PharmGKB disease relationship for ADCY9 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    AsthmaPD  FA  GN  12972952
    About this table

    Human Gene Mutation Database: ADCY9
    Genetic Association Database: ADCY9
    Human Genome Epidemiology Navigator: ADCY9 (4 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/28 PubMed articles for ADCY9 gene (see all 28 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 115 HGNC: 240 AceView: ADCY9 Ensembl:ENSG00000162104 euGenes: HUgn115
    ECgene: ADCY9 H-InvDB: ADCY9
    (According to HUGE)
    About This Section

    HUGE: KIAA0520
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADCY9:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADCY9-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADCY9 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADCY9 Small molecules for ADCY9
     "Your Favorite Gene" Pathwaysfeedback


      
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     Drugs for ADCY9
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