Aliases for ADCY4 Gene
External Ids for ADCY4 Gene
Previous GeneCards Identifiers for ADCY4 Gene
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
GeneCards Summary for ADCY4 Gene
ADCY4 (Adenylate Cyclase 4) is a Protein Coding gene. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Circadian entrainment. GO annotations related to this gene include phosphorus-oxygen lyase activity and adenylate cyclase activity. An important paralog of this gene is ADCY2.
UniProtKB/Swiss-Prot for ADCY4 Gene
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
Adenylyl Cyclases (AC) are a group of enzymes that convert adenosine-5'-triphosphate (ATP) into 3',5'-adenosine monophosphate (cyclic AMP/cAMP) and pyrophosphate. There are ten different mammalian isoforms of adenylyl cylase; nine of which are membrane-bound.