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ADCY1 Gene

protein-coding   GIFtS: 63

GC07P045580
adenylate cyclase 1 (brain)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
AC1 1, 2
EC 4.6.1.1 3
Descriptions
3',5'-cyclic AMP synthetase 2
ATP pyrophosphate-lyase 2
ATP pyrophosphate-lyase 1 3
Adenylate cyclase type I 2, 3
Adenylyl cyclase 1 3
Ca(2+)/calmodulin-activated adenylyl cyclase 2, 3
adenyl cyclase 2
adenylate cyclase 1 2
adenylate cyclase 1 (brain) 2
External Ids
HGNC: 2321
Entrez Gene: 1072
UniProtKB: Q088283
Ensembl: ENSG000001647427
Search outside databases for aliases for ADCY1 gene

Previous GC identifers: GC07P045296 GC07P045354 GC07P045387

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ADCY1:
This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is
involved in pattern formation of the brain. [provided by RefSeq]

UniProtKB/Swiss-Prot: ADCY1_HUMAN, Q08828
Function: This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes
in the central nervous system. It may play a role in memory acquisition and learning

Gene Wiki entry for ADCY1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADCY1 gene  

Entrez Gene cytogenetic band: 7p13-p12   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13-p12

ADCY1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P045580:     (about GC identifiers)

Start:
45,580,646 bp from pter
End:
45,729,237 bp from pter
Size:
148,592 bases
Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 45,653,342-45,802,043     
RefSeq DNA sequence:
NC_000007.12  NT_007819.16  NT_079592.2  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ADCY1_HUMAN, Q08828 (See protein sequence)
Recommended Name: Adenylate cyclase type 1  
Size: 1119 amino acids; 123440 Da
Cofactor: Binds 2 magnesium ions per subunit (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: A4D2L8 Q75MI1

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_066939.1  

    ENSEMBL proteins: 
    ENSP00000297323 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Adenylate cyclase 1)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane NAS--
    About this table

    Antibodies for ADCY1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Adenylate cyclase 1), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for ADCY1

    Assays for ADCY1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    2 InterPro domains/families:
     IPR001054 A/G_cyclase
     IPR018297 A/G_cyclase_CS


       GeneDecks  ADCY1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q08828

    ProtoNet protein and cluster: Q08828

    1 Blocks protein family: IPB009398 Adenylate cyclase-like

    UniProtKB/Swiss-Prot: ADCY1_HUMAN, Q08828
    Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family
    Similarity: Contains 2 guanylate cyclase domains

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADCY1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADCY1)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021116

                  Applied Biosystems Silencer® siRNAs for ADCY1

                  Sigma-Aldrich siRNA and siRNA Panels for ADCY1  
                         Sigma-Aldrich shRNA for ADCY1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_021116
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_021116
                                     untagged cDNA clones in CMV expression vector (see all 3): BC036858 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_021116

    UniProtKB/Swiss-Prot: ADCY1_HUMAN, Q08828
    Function: This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes
    in the central nervous system. It may play a role in memory acquisition and learning
    Catalytic activity: ATP = 3',5'-cyclic AMP + diphosphate
    Enzyme regulation: Activated by calcium/calmodulin. Inhibited by the G protein beta and gamma
    subunit complex
    Enzyme Number (IUBMB): EC 4.6.1.1 

    Genatlas biochemistry entry for ADCY1:
    adenylyl cyclase,type I,calmodulin sensitive,fetal brain

    4 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Adcy1):

    behavior/neurologicalhomeostasis/metabolismnervous systemtouch/vibrissae

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287 magnesium ion binding IEA--
    GO:0005516 calmodulin binding NAS--
    GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity NAS8314585
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    5/18 Invitrogen iPath™ Online BioAtlas - Pathways for ADCY1 (see all 18 ) (Maps provided by GeneGo):
     cAMP signaling
     Hedgehog and PTH signaling pathways participation in bone and cartilage development
     A2B receptor: action via G-protein alpha s (map 1)
     G-Protein alpha-i signaling cascades
     G-protein families signaling pathway

       GeneDecks  ADCY1 for the pathways selected above  
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    5/21 Millipore Pathways for ADCY1 (see all 21 )
     Adenylate cyclase-activating neuropeptides
     Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
     Development A1 receptor signaling
     Transcription PPAR Pathway
     Development Role of Activin A in cell differentiation and proliferation

       GeneDecks  ADCY1 for the pathways selected above  
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    5/23 Sigma-Aldrich "Your Favorite Gene" Pathways for  ADCY1  (Your Favorite Gene powered by Ingenuity) (see all 23
     Synaptic Long Term Potentiation
     Purine Metabolism
     Dopamine Receptor Signaling
     Cardiac &beta
     PPAR&alpha

       GeneDecks  ADCY1 for the pathways selected above  
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    5/7 Kegg Pathways  (Kegg details for ADCY1) (see all 7 ):
     hsa00230 Purine metabolism
     hsa04020 Calcium signaling pathway
     hsa04270 Vascular smooth muscle contraction
     hsa04540 Gap junction
     hsa04720 Long-term potentiation

       GeneDecks  ADCY1 for the pathways selected above  
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    5/108 Interacting proteins for ADCY1 (ENSP000002973233) via UniProtKB, MINT, and/or STRING (see all 108 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM3ENSP000002912953STRING (score=.972)
    GNAI2ENSP000003129993STRING (score=.972)
    ADCY2ENSP000003719713STRING (score=.965)
    PRKAR2BENSP000002657173STRING (score=.954)
    PDE1AENSP000003092693STRING (score=.953)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006171 cAMP biosynthetic process NAS--
    GO:0007616 long-term memory IEA--
    GO:0009755 hormone-mediated signaling EXP12626323
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for ADCY1
    Sigma-Aldrich Small Molecules for ADCY1:
    Inhibitor

    Compounds for ADCY1 available from Tocris Bioscience
    CompoundAction CAS number
    SQ 22536Adenylyl cyclase inhibitor[17318-31-9]
    NKH 477Water-soluble adenylyl cyclase activator[138605-00-2]
    PACAP 1-38Potent stimulator of adenylyl cyclase
    ForskolinAdenylyl cyclase activator[66575-29-9]
    PACAP 1-27Potent stimulator of adenylyl cyclase[137061-48-4]
    About this table


    10/21 Novoseek chemical compound relationships for ADCY1 gene (see all 21 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    2',5'-dideoxyadenosine 70.33 7 7512387 (1), 17294519 (1), 7530840 (1)
    forskolin 69.89 18 8853375 (2), 8392469 (1), 17611668 (1), 7704910 (1) (see all 15)
    cyclic amp 66.46 9 11515719 (2), 1847586 (1), 15845377 (1), 16201743 (1) (see all 7)
    1,9-dideoxyforskolin 62.58 1 8853375 (1)
    dbc-amp 60.10 3 1829779 (1), 8625744 (1), 1372296 (1)
    prostaglandin 20.41 4 8908618 (2), 15845377 (1)
    progesterone 18.34 4 14567882 (1), 7530840 (1), 15131261 (1), 11596304 (1)
    atp 17.24 4 12359956 (1), 9338086 (1), 18301971 (1)
    adp 17.11 3 12149126 (1)
    katp 16.81 1 11336627 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ADCY1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADCY1)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021116

                  Sigma-Aldrich siRNA and siRNA Panels for ADCY1  
                         Sigma-Aldrich shRNA for ADCY1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_021116  

    REFSEQ mRNAs for ADCY1 gene: 

    NM_021116.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_021116  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_021116
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_021116
                                     untagged cDNA clones in CMV expression vector (see all 3): BC036858 

    Additional cDNA sequence: 

    AB209496.1 AF086306.1 AF497515.1 AK024415.1 AK055343.1 AK095518.1 AK095665.1 BC036858.1 
    BC041473.1 CR596735.1 CR612961.1 L05500.1 

    4 DOTS entries:

    DT.115205  DT.453040  DT.100790903  DT.101975235 

    24/167 AceView cDNA sequences (see all 167 ):

    L05500 AA351841 AL120172 CB162512 BM695328 AV650659 D55782 AL534368 
    W69791 AA497018 CB156728 AF086306 BM926997 BM926775 BC041473 BX095677 
    BM479247 CR612961 AW058472 AA325723 AK055343 AI858628 BQ638576 CA334785 

    highest scoring ESTs for ADCY1:

    L05500 R37248 R39984 AA020807 AA021121 AA046447 AA053983 AA082405 AA325723 AA351841 

    Unigene Cluster for ADCY1:

    Adenylate cyclase 1 (brain)
    Hs.192215  [show with all ESTs]
    Unigene Representative Sequence: NM_021116


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000297323  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADCY1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADCY1

    1 / 2 / 3

    12 probe-sets matching ADCY1 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    33353_at2, 3 U95-A 1 1.00 1.00 0.84 1.02 W26466 0.60 1.00 0.82 1

    67169_at2, 3 U95-E 1 1.00 1.00 0.21 1.45 R39984 1.00 1.00 1.00 1

    61740_at2, 3 U95-C 1 1.00 1.00 0.77 1.17 R37248 1.00 1.00 1.00 1

    35580_at2, 3 U95-A 2 1.00 0.94 0.55 0.42 L05500 1.00 1.00 1.00 1

    213245_at2, 3 U133-A 1 1.00 1.00 -- -- AL120173 0.80 1.00 0.91 1

    215348_at2, 3 U133-A 1 1.00 1.00 -- -- L05500 1.00 1.00 1.00 1

    232062_at2, 3 U133-B 1 1.00 1.00 -- -- AK024415 0.80 1.00 0.91 1

    235049_at2, 3 U133-B 1 0.91 1.00 -- -- AA021120 0.60 1.00 0.82 1

    213245_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    215348_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    232062_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    235049_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
    GeneDecks  ADCY1 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ATAGATTTGT

    SOURCE GeneReport for Unigene cluster: Hs.192215

    Expression variation in blood from EXPOLDB for ADCY1

    UniProtKB/Swiss-Prot: ADCY1_HUMAN, Q08828
    Tissue specificity: Brain, retina and adrenal medulla

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ADCY1 gene from 5/9 species (see all 9 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    chimpanzee
    (Pan troglodytes)
    ADCY11   -- adenylate cyclase 1 (brain) 97.77(n)
    97.59(a)
    463392  XM_519081.2  XP_519081.2 
    cow
    (Bos taurus)
    ADCY11   -- adenylate cyclase 1 (brain) 88.68(n)
    92.94(a)
    281601  NM_174229.2  NP_776654.1 
    rat
    (Rattus norvegicus)
    Adcy11   -- adenylate cyclase 1 (brain) 87.6(n)
    92.31(a)
    305509  XM_223616.4  XP_223616.4 
    mouse
    (Mus musculus)
    Adcy11, 5 11 (1.25 cM)5
    adenylate cyclase 11, 5 88.13(n)1
    92.67(a)1
    4325301  NM_009622.11  NP_033752.11 
     AF0539795  AF0539805  (see all 20)
    chicken
    (Gallus gallus)
    ADCY11   -- adenylate cyclase 1 (brain) 74.53(n)
    82.92(a)
    420788  XM_418883.2  XP_418883.2 
    About this table        Species with no ortholog for ADCY1

    ENSEMBL Gene Tree for ADCY1
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADCY1 gene
    ADCY52  ADCY82  ADCY62  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/696 NCBI SNPs in ADCY1 are shown (see all 696 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 195)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 7 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs24611271,2
    A,C,F,H,O45724331(-) TGGAAC/TGGATC 1 -- ut317Minor allele frequency- T:0.30NA EU EA WA 560
    rs127541,2
    A,C,F,H,O45727719(+) GGTTGT/GATTTG 1 -- ut3113Minor allele frequency- G:0.28MN NA EU EA WA 1292
    rs22804961,2
    A,C,F,H,O45723522(-) AAAAGG/CAAGTT 1 -- ut31 trp312Minor allele frequency- C:0.11EA EU WA NA 2396
    rs78066071,2
    A,C,F,H45726813(+) TCTATT/GAATAC 1 -- ut31 ese34Minor allele frequency- G:0.03EU EA WA 416
    rs24712671,2
    A,C,F,H45725787(-) CACACG/AACAGA 1 -- ut31 ese38Minor allele frequency- A:0.36EU EA WA 834
    rs37356661,2
    C,F,H45728477(+) TGCACA/CAAGGG 1 -- ut31 ese38Minor allele frequency- C:0.09EA EU WA NA 2052
    --
    rs11286021,2
    C,F,H45729221(+) AAAGGG/AAAAAA 1 -- ut316Minor allele frequency- A:0.09EU EA NA 390
    rs22804951,2
    C,F,O45723868(-) CCACCC/TGGGCC 1 -- ut31 ese35Minor allele frequency- N:0.00EA NA 1710
    rs102259801,2
    C,F,H45724372(+) GACCAA/GCGGTG 1 -- ut31 ese311Minor allele frequency- G:0.07EU EA WA NA 982
    rs37356691,2
    C,F,H45721107(-) ATCTTC/TCATCA 1 -- ut3112Minor allele frequency- T:0.26EU EA WA 1258
    About this table

    HapMap Linkage Disequilibrium images for ADCY1 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 103072

    5 Novoseek disease relationships for ADCY1 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    cholera 42.60 2 12736381 (1), 1661420 (1)
    thyroid carcinoma 16.65 1 7478621 (1)
    adenoma 5.14 1 11420487 (1)
    leukemia 0.00 1 2154651 (1)
    ischemia 0.00 1 16297936 (1)
    About this table

    Human Genome Epidemiology Navigator: ADCY1 (2 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/133 PubMed articles for ADCY1 gene (see all 133 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 107 HGNC: 232 AceView: ADCY1 Ensembl:ENSG00000164742 euGenes: HUgn107
    ECgene: ADCY1 H-InvDB: ADCY1
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADCY1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADCY1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADCY1 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADCY1 Small molecules for ADCY1
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant Proteins
    (Adenylate cyclase 1)
     Antibodies (Adenylate cyclase 1)
     Search OriGene for ADCY1
     Tocris compounds for ADCY1




     Drugs for ADCY1
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