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ADCK2 Gene

protein-coding   GIFtS: 48
GCID: GC07P140372

AarF Domain Containing Kinase 2

  See ADCK2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
AarF Domain Containing Kinase 21 2
AARF2 3
Putative Ubiquinone Biosynthesis Protein AarF2
Uncharacterized AarF Domain-Containing Protein Kinase 22
EC 2.7.11.-3

External Ids:    HGNC: 190391   Entrez Gene: 909562   Ensembl: ENSG000001335977   UniProtKB: Q7Z6953   

Export aliases for ADCK2 gene to outside databases

Previous GC identifers: GC07P139703 GC07P139780 GC07P139826 GC07P140019 GC07P134668


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ADCK2 Gene:
ADCK2 (aarF domain containing kinase 2) is a protein-coding gene. Diseases associated with ADCK2 include klippel-feil syndrome. GO annotations related to this gene include protein serine/threonine kinase activity.

UniProtKB/Swiss-Prot: ADCK2_HUMAN, Q7Z695
Function: The function of this protein is not yet clear. It is not known if it has protein kinase activity and
what type of substrate it would phosphorylate (Ser, Thr or Tyr)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the ADCK2 gene promoter:
         COUP-TF1   AML1a   COUP   HNF-4alpha2   HNF-4alpha1   RORalpha1   PPAR-gamma1   COUP-TF   STAT3   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADCK2 promoter sequence
   Search Chromatin IP Primers for ADCK2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADCK2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q34   Ensembl cytogenetic band:  7q34   HGNC cytogenetic band: 7q34

ADCK2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADCK2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P140372:  view genomic region     (about GC identifiers)

Start:
140,372,953 bp from pter      End:
140,396,061 bp from pter
Size:
23,109 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 139,711,129-139,733,084     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ADCK2_HUMAN, Q7Z695 (See protein sequence)
Recommended Name: Uncharacterized aarF domain-containing protein kinase 2  
Size: 626 amino acids; 68982 Da
Sequence caution: Sequence=AAH14107.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: Q96CN6 Q9Y6T5

Explore the universe of human proteins at neXtProt for ADCK2: NX_Q7Z695

Explore proteomics data for ADCK2 at MOPED


See ADCK2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_443085.2  
ENSEMBL proteins: 
 ENSP00000072869   ENSP00000420512   ENSP00000417367   ENSP00000420288  

ADCK2 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for ADCK2

 
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antibodies-online proteins for ADCK2 (3 products) 

 
antibodies-online peptides for ADCK2

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antibodies-online antibodies for ADCK2 (39 products) 

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antibodies-online kits for ADCK2 (4 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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IUPHAR Guide to PHARMACOLOGY protein family classification: aarF domain containing kinase 2
ABC1-A subfamily

2 InterPro protein domains:
 IPR011009 Kinase-like_dom
 IPR004147 UbiB_dom

Graphical View of Domain Structure for InterPro Entry Q7Z695

ProtoNet protein and cluster: Q7Z695

1 Blocks protein domain: IPB004147 ABC1 protein

UniProtKB/Swiss-Prot: ADCK2_HUMAN, Q7Z695
Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family
Similarity: Contains 1 protein kinase domain


Find genes that share domains with ADCK2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ADCK2_HUMAN, Q7Z695
Function: The function of this protein is not yet clear. It is not known if it has protein kinase activity and
what type of substrate it would phosphorylate (Ser, Thr or Tyr)

     Enzyme Number (IUBMB): EC 2.7.11.-1

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004672protein kinase activity ----
GO:0004674protein serine/threonine kinase activity IEA--
GO:0005524ATP binding IEA--
GO:0016772transferase activity, transferring phosphorus-containing groups ----
     
Find genes that share ontologies with ADCK2           About GenesLikeMe


Phenotypes:
     4 GenomeRNAi human phenotypes for ADCK2:
 Decreased substrate adherent c  Increased G2M DNA content  Increased gamma-H2AX phosphory  Upregulation of Wnt/beta-caten 

     1 MGI phenotypic allele for Adck2 (no phenotypes)

Find genes that share phenotypes with ADCK2           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Adck2tm1(KOMP)Vlcg for ADCK2

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADCK2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ADCK2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ADCK2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ADCK2

miRNA
Products:
    
miRTarBase miRNAs that target ADCK2:
hsa-let-7b-5p (MIRT052161), hsa-mir-484 (MIRT042051), hsa-mir-615-3p (MIRT040368)

Block miRNA regulation of human, mouse, rat ADCK2 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate ADCK2:
hsa-miR-22
SwitchGear 3'UTR luciferase reporter plasmidADCK2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for ADCK2
Predesigned siRNA for gene silencing in human, mouse, rat ADCK2

Gene Editing
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OriGene ORF clones in mouse, rat for ADCK2
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GenScript: all cDNA clones in your preferred vector: ADCK2 (NM_052853)
Sino Biological Human cDNA Clone for ADCK2
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADCK2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADCK2
Addgene plasmids for ADCK2 

Cell Line
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GenScript Custom overexpressing Cell Line Services for ADCK2
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADCK2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
ADCK2_HUMAN, Q7Z695: Membrane; Single-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3
mitochondrion2
cytosol1
endoplasmic reticulum1
golgi apparatus1
nucleus1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IEA--
GO:0016021integral component of membrane IEA--

Find genes that share ontologies with ADCK2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ADCK2
Interactions:

    Search GeneGlobe Interaction Network for ADCK2

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

Selected Interacting proteins for ADCK2 (Q7Z6953 ENSP000000728694) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
InteractantInteraction Details
GeneCardExternal ID(s)
YWHAQP273483, ENSP000002380814I2D: score=1 STRING: ENSP00000238081
MIPEPENSP000003716074STRING: ENSP00000371607
POLGENSP000002681244STRING: ENSP00000268124
UBCENSP000003448184STRING: ENSP00000344818
FREM2ENSP000002804814STRING: ENSP00000280481
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006468protein phosphorylation ----

Find genes that share ontologies with ADCK2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ADCK2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for ADCK2 gene: 
NM_052853.3  

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000072869(uc003vvy.1) ENST00000476491(uc003vvz.3) ENST00000483369
ENST00000498423 ENST00000473512
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ADCK2 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate ADCK2:
hsa-miR-22
SwitchGear 3'UTR luciferase reporter plasmidADCK2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ADCK2
Predesigned siRNA for gene silencing in human, mouse, rat ADCK2
Clone
Products:
     
OriGene clones in human, mouse for ADCK2 (see all 7)
OriGene ORF clones in mouse, rat for ADCK2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ADCK2 (NM_052853)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADCK2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADCK2
Addgene plasmids for ADCK2 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for ADCK2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADCK2
  QuantiTect SYBR Green Assays in human, mouse, rat ADCK2
  QuantiFast Probe-based Assays in human, mouse, rat ADCK2

Selected AceView cDNA sequences (see all 415):

BQ896813 AI017674 BC065735 F21673 F28704 BU608811 CR542121 AA593450 
AF050639 AW268646 BE745459 AI620342 BU158172 AI936545 CR590326 AA101075 
AA699958 BM823023 F27134 CB109485 BM998544 BM757334 BQ286123 BX331595 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ADCK2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCTTCCTCTG
ADCK2 Expression
About this image

ADCK2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ADCK2 Protein Expression
    Custom PCR Arrays for ADCK2
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for ADCK2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADCK2
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QuantiFast Probe-based Assays in human, mouse, rat ADCK2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADCK2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for ADCK2 gene from Selected species (see all 16)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Adck21 , 5 aarF domain containing kinase 21, 5 78.25(n)1
75.69(a)1
  6 (18.39 cM)5
578691  NM_178873.31  NP_849204.11 
 395738735 
chicken
(Gallus gallus)
Aves ADCK21 aarF domain containing kinase 2 65.45(n)
61.88(a)
  418116  XM_416350.4  XP_416350.3 
lizard
(Anolis carolinensis)
Reptilia ADCK26
aarF domain containing kinase 2
59(a)
1 ↔ 1
5(15567403-15574371)
tropical clawed frog
(Xenopus tropicalis)
Amphibia adck21 aarF domain containing kinase 2 61.3(n)
58.14(a)
  100486101  XM_002941614.2  XP_002941660.2 
zebrafish
(Danio rerio)
Actinopterygii LOC5720871 uncharacterized LOC572087 60.19(n)
56.99(a)
  572087  XM_695757.5  XP_700849.4 
worm
(Caenorhabditis elegans)
Secernentea Y32H12A.71 Y32H12A.7 48.26(n)
40.6(a)
  175741  NM_065749.5  NP_498150.2 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes (YPL109C)4
YPL109C1
Putative protein of unknown function; the authentic, more4
YPL109C1
46.11(n)1
37.88(a)1
  16(347389-345264)4
8559951, 4  NP_015216.31, 4 


ENSEMBL Gene Tree for ADCK2 (if available)
TreeFam Gene Tree for ADCK2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ADCK2 (see all 472)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1138845631,2
C,F--140371108(+) AGGCTG/AGTCTC 1 -- us2k11Minor allele frequency- A:0.50NA 2
rs1919084691,2
--140371111(+) CTGGTC/GTCGAA 1 -- us2k10--------
rs1838202741,2
--140371113(+) GGTCTC/TGAATG 1 -- us2k10--------
rs1892444171,2
C--140371169(+) GATTAC/GAGGTG 1 -- us2k10--------
rs1437520731,2
C--140371183(+) GCCACC/TGTGCC 1 -- us2k10--------
rs735056451,2
C,F--140371348(+) TGTGTC/GCGCTT 1 -- us2k15Minor allele frequency- G:0.13WA CSA NA EA 362
rs1911913411,2
--140371413(+) CAAATA/GTGAGA 1 -- us2k10--------
rs1481492081,2
--140371476(+) TATGGC/GCTTTC 1 -- us2k10--------
rs29685591,2
C,F,A,H--140371545(-) AGGAAC/TTGGAT 1 -- us2k121Minor allele frequency- T:0.33NS EA NA WA CSA 2347
rs1419532571,2
C--140371787(+) GGTCGC/TCGTCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for ADCK2 (140372953 - 140396061 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for ADCK2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv831158CNV Loss17160897
nsv831157CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ADCK2
DNA2.0 Custom Variant and Variant Library Synthesis for ADCK2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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1 disease for ADCK2:    
About MalaCards
klippel-feil syndrome

1 disease from the University of Copenhagen DISEASES database for ADCK2:
Klippel-Feil syndrome

Find genes that share disorders with ADCK2           About GenesLikeMe

Genetic Association Database (GAD): ADCK2
Human Genome Epidemiology (HuGE) Navigator: ADCK2 (2 documents)

Export disorders for ADCK2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ADCK2 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with ADCK2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
  4. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)
  5. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (Transplantation 2010)
  6. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)
  7. Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. (PubMed id 15324660)1 Jin J.... Pawson T. (Curr. Biol. 2004)
  8. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (Science 2003)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (Genome Res. 1997)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 90956 HGNC: 19039 AceView: NDUFB2andADCK2 Ensembl:ENSG00000133597 euGenes: HUgn90956
ECgene: ADCK2 H-InvDB: ADCK2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ADCK2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ADCK2 gene:
Search GeneIP for patents involving ADCK2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 OriGene Antibodies for ADCK2   OriGene RNAi products in human, mouse, rat for ADCK2  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ADCK2  
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 OriGene Custom Antibody Services for ADCK2   OriGene Custom Protein Services for ADCK2  

 
 
 Block miRNA regulation of human, mouse, rat ADCK2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ADCK2
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADCK2 Predesigned siRNA for gene silencing in human, mouse, rat ADCK2
 QuantiFast Probe-based Assays in human, mouse, rat ADCK2 QuantiTect SYBR Green Assays in human, mouse, rat ADCK2
 Custom PCR Arrays for ADCK2 Search Chromatin IP Primers for ADCK2
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADCK2  Search GeneGlobe Interaction Network for ADCK2
 Regulatory tfbs in ADCK2 promoter
 GenScript Custom Purified and Recombinant Proteins Services for ADCK2 GenScript cDNA clones with any tag delivered in your preferred vector for ADCK2
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 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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 Search Tocris compounds for ADCK2
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 ADCK2 antibodies
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 See all of Abcam's Antibodies, Kits and Proteins for ADCK2
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 Browse ProSpec Recombinant Proteins
 Proteins for ADCK2
 Antibodies for ADCK2
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 Browse ESI BIO Cell Lines and PureStem Progenitors for ADCK2
 Gene Synthesis
 Protein Engineering
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 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADCK2
 SwitchGear 3'UTR luciferase reporter plasmids for ADCK2
 SwitchGear Promoter luciferase reporter plasmids for ADCK2
 ThermoFisher Antibodies for ADCK2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADCK2
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ADCK2
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ADCK2
 LSBio Antibodies in human, mouse, rat for ADCK2
 Browse compounds at ApexBio
 Addgene plasmids for ADCK2
  Search eBioscience for proteins for ADCK2
  Search eBioscience for elisas for ADCK2
  eBioscience FlowRNA Probe Sets
Customized transgenic rodents for:
 Humanization
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 antibodies-online antibodies for ADCK2 (39 products)
 antibodies-online kits for ADCK2 (4 products)
 antibodies-online peptides for ADCK2
 antibodies-online proteins for ADCK2 (3 products)
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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