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ADAT2 Gene

protein-coding   GIFtS: 43
GCID: GC06M143789

Adenosine Deaminase, TRNA-Specific 2

(Previous names: deaminase domain containing 1, adenosine deaminase, tRNA-specific...)
(Previous symbol: DEADC1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Adenosine Deaminase, TRNA-Specific 21 2     Adenosine Deaminase, TRNA-Specific 2, TAD2 Homolog2
DEADC11 2 3     dJ20N22
Deaminase Domain Containing 11 2     dJ20N2.12
Deaminase Domain-Containing Protein 12 3     TRNA-Specific Adenosine Deaminase 22
TRNA-Specific Adenosine-34 Deaminase Subunit ADAT22 3     TRNA-Specific Adenosine Deaminase 2 Homolog2
TAD22 5     EC 3.5.4.-3
Adenosine Deaminase, TRNA-Specific 2, TAD2 Homolog (S. Cerevisiae)1     EC 3.5.48
TRNA-Specific Adenosine Deaminase 2 Homolog (S. Cerevisiae)1     

External Ids:    HGNC: 211721   Entrez Gene: 1346372   Ensembl: ENSG000001890077   OMIM: 6153885   UniProtKB: Q7Z6V53   

Export aliases for ADAT2 gene to outside databases

Previous GC identifer: GC06M141307


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ADAT2 Gene:
ADAT2 (adenosine deaminase, tRNA-specific 2) is a protein-coding gene. GO annotations related to this gene include hydrolase activity.

UniProtKB/Swiss-Prot: ADAT2_HUMAN, Q7Z6V5
Function: Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the ADAT2 gene promoter:
         MEF-2   POU3F2   LCR-F1   YY1   GATA-1   MEF-2A   CREB   HFH-1   deltaCREB   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADAT2 promoter sequence
   Search Chromatin IP Primers for ADAT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ADAT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q24.2   Ensembl cytogenetic band:  6q24.2   HGNC cytogenetic band: 6q24.2

ADAT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADAT2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M143789:  view genomic region     (about GC identifiers)

Start:
143,743,969 bp from pter      End:
143,771,841 bp from pter
Size:
27,873 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ADAT2_HUMAN, Q7Z6V5 (See protein sequence)
Recommended Name: tRNA-specific adenosine deaminase 2  
Size: 191 amino acids; 21046 Da
Cofactor: Zinc (By similarity)
Sequence caution: Sequence=AAH37955.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for ADAT2:
3DH1 (3D)    
Secondary accessions: A6NL12 B3KWY3 Q7Z327 Q8IY39
Alternative splicing: 2 isoforms:  Q7Z6V5-1   Q7Z6V5-2   

Explore the universe of human proteins at neXtProt for ADAT2: NX_Q7Z6V5

Explore proteomics data for ADAT2 at MOPED

3 DME Specific Peptides for ADAT2 (Q7Z6V5)
 RFGGCGSV  LYVTVEPC  TKNATRHAEMVA 


See ADAT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001273188.1  NP_872309.2  

ENSEMBL proteins: 
 ENSP00000475651   ENSP00000237283  

ADAT2 Human Recombinant Protein Products:

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OriGene Purified Protein for ADAT2
OriGene Protein Over-expression Lysate for ADAT2
OriGene MassSpec for ADAT2
OriGene Custom Protein Services for ADAT2
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Novus Biologicals ADAT2 Proteins
Novus Biologicals ADAT2 Lysate
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Browse Sino Biological Cell Lysates
ProSpec Recombinant Protein for ADAT2
Cloud-Clone Corp. Proteins for ADAT2

 
Search eBioscience for Proteins for ADAT2 

 
antibodies-online proteins for ADAT2 (17 products) 

 
antibodies-online peptides for ADAT2

ADAT2 Antibody Products:

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Novus Biologicals ADAT2 Antibody
Abcam antibodies for ADAT2
Cloud-Clone Corp. Antibodies for ADAT2
Search ThermoFisher Antibodies for ADAT2
antibodies-online antibodies for ADAT2 (7 products) 

ADAT2 Assay Products:

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Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for ADAT2
Cloud-Clone Corp. CLIAs for ADAT2
Search eBioscience for ELISAs for ADAT2 
antibodies-online kits for ADAT2 (3 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:
 IPR016192 APOBEC/CMP_deaminase_Zn-bd
 IPR002125 CMP_dCMP_Zn-bd
 IPR028883 tRNA_aden_deaminase
 IPR016193 Cytidine_deaminase-like

Graphical View of Domain Structure for InterPro Entry Q7Z6V5

ProtoNet protein and cluster: Q7Z6V5

1 Blocks protein domain: IPB002125 Cytidine/deoxycytidylate deaminase

UniProtKB/Swiss-Prot: ADAT2_HUMAN, Q7Z6V5
Similarity: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily


Find genes that share domains with ADAT2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ADAT2_HUMAN, Q7Z6V5
Function: Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)

     Enzyme Numbers (IUBMB): EC 3.5.42 EC 3.5.4.-1

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003824catalytic activity ----
GO:0008251tRNA-specific adenosine deaminase activity IEA--
GO:0008270zinc ion binding IEA--
GO:0016787hydrolase activity ----
     
Find genes that share ontologies with ADAT2           About GenesLikeMe


Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for ADAT2

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat ADAT2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ADAT2 (see all 70):
hsa-miR-411* hsa-miR-361-5p hsa-miR-376b hsa-miR-138-2* hsa-miR-4275 hsa-miR-192* hsa-miR-34c-5p hsa-miR-3688-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for ADAT2
Predesigned siRNA for gene silencing in human, mouse, rat ADAT2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ADAT2

Clone
Products:
     
OriGene clones in human, mouse for ADAT2 (see all 6)
OriGene ORF clones in mouse, rat for ADAT2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ADAT2 (NM_182503)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADAT2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADAT2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ADAT2
Browse ESI BIO Cell Lines and PureStem Progenitors for ADAT2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAT2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
extracellular1
golgi apparatus1
mitochondrion1
nucleus1
plasma membrane1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ADAT2
Interactions:

    Search GeneGlobe Interaction Network for ADAT2

STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

Selected Interacting proteins for ADAT2 (Q7Z6V53 ENSP000002372834) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
InteractantInteraction Details
GeneCardExternal ID(s)
SNRPD2P623163, ENSP000003423744I2D: score=3 STRING: ENSP00000342374
TRMT10AQ8TBZ63, ENSP000002739624I2D: score=1 STRING: ENSP00000273962
ATE1O952603I2D: score=1 
CNOT3O751753I2D: score=1 
CTU1Q7Z7A33I2D: score=1 
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002100tRNA wobble adenosine to inosine editing IEA--
GO:0008033tRNA processing ----

Find genes that share ontologies with ADAT2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ADAT2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for ADAT2 gene (2 alternative transcripts): 
NM_001286259.1  NM_182503.2  

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000606514 ENST00000237283(uc003qjj.3 uc003qjk.1) ENST00000367593

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ADAT2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ADAT2 (see all 70):
hsa-miR-411* hsa-miR-361-5p hsa-miR-376b hsa-miR-138-2* hsa-miR-4275 hsa-miR-192* hsa-miR-34c-5p hsa-miR-3688-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ADAT2
Predesigned siRNA for gene silencing in human, mouse, rat ADAT2
Clone
Products:
     
OriGene clones in human, mouse for ADAT2 (see all 6)
OriGene ORF clones in mouse, rat for ADAT2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ADAT2 (NM_182503)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ADAT2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADAT2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ADAT2
OriGene qSTAR qPCR primer pairs in human, mouse for ADAT2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADAT2
  QuantiTect SYBR Green Assays in human, mouse, rat ADAT2
  QuantiFast Probe-based Assays in human, mouse, rat ADAT2

Selected AceView cDNA sequences (see all 66):

BG391422 AW592640 BQ440985 CR616838 BE791897 AI304628 BM553554 BX108973 
AI148314 BX476676 BX281806 BE790527 AI283835 BX471033 BE159780 BQ019510 
AK126201 CB321793 NM_182503 AW303386 BF034101 BC037955 AI168096 AI273734 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ADAT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTAAAATAAA
ADAT2 Expression
About this image

ADAT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ADAT2 Protein Expression
    Custom PCR Arrays for ADAT2
Primer
Products:
OriGene qPCR primer pairs and template standards for ADAT2
OriGene qSTAR qPCR primer pairs in human, mouse for ADAT2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ADAT2
QuantiTect SYBR Green Assays in human, mouse, rat ADAT2
QuantiFast Probe-based Assays in human, mouse, rat ADAT2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAT2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for ADAT2 gene from Selected species (see all 20)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Adat21 , 5 adenosine deaminase, tRNA-specific 2, TAD2 homolog more5
adenosine deaminase, tRNA-specific 21
83.94(n)1
89.01(a)1
  10 (4.94 cM)5
667571  NM_025748.41  NP_080024.31 
 135528945 
chicken
(Gallus gallus)
Aves ADAT21 adenosine deaminase, tRNA-specific 2 72.12(n)
74.27(a)
  421670  XM_419709.4  XP_419709.1 
lizard
(Anolis carolinensis)
Reptilia ADAT26
adenosine deaminase, tRNA-specific 2
47(a)
1 ↔ 1
1(203865152-203878760)
tropical clawed frog
(Xenopus tropicalis)
Amphibia adat21 adenosine deaminase, tRNA-specific 2 73.96(n)
74.56(a)
  780017  NM_001079094.1  NP_001072562.1 
zebrafish
(Danio rerio)
Actinopterygii adat21 adenosine deaminase, tRNA-specific 2, TAD2 homolog more 71.84(n)
76.4(a)
  100034610  NM_001083097.1  NP_001076566.1 
fruit fly
(Drosophila melanogaster)
Insecta CG52921 CG5292 52.02(n)
45.86(a)
  42079  NM_142353.3  NP_650610.1 
worm
(Caenorhabditis elegans)
Secernentea CELE_JC8.41 CELE_JC8.4 51.83(n)
44.51(a)
  178281  NM_070145.1  NP_502546.1 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TAD2(YJL035C)4 Subunit of tRNA-specific adenosine-34 deaminase, forms more   --   10(381001-380249) 853417  NP_012499.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons emb21911 emb2191 55.49(n)
52.17(a)
  841237  NM_103714.3  NP_564523.3 
rice
(Oryza sativa)
Liliopsida Os03g03219001 Os03g0321900 54.12(n)
50(a)
  4332682  NM_001056499.1  NP_001049964.1 


ENSEMBL Gene Tree for ADAT2 (if available)
TreeFam Gene Tree for ADAT2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ADAT2 gene

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1 Pseudogenes.org Pseudogene for ADAT2
PGOHUM00000233527


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ADAT2 (see all 547)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs735786981,2
C,F--143743634(+) ATGCAC/TGTTTA 1 -- ds50013Minor allele frequency- T:0.12WA CSA 122
rs1867512661,2
--143743660(+) GCCCTA/GAGGTA 1 -- ds50010--------
rs1907891371,2
--143743715(+) ATGTCA/CCCGGT 1 -- ds50010--------
rs768269031,2
F--143743731(+) AGTTTC/GCTTTA 1 -- ds50011Minor allele frequency- G:0.02NA 120
rs1826118701,2
--143743846(+) CTAGCC/TCCTTC 1 -- ds50010--------
rs94966161,2
C,F,H--143744037(+) CTTGCC/TACTCT 1 -- ut317Minor allele frequency- T:0.21NS EA NA WA 658
rs1455622541,2
C--143744127(+) TAGACC/TAACTT 1 -- ut310--------
rs1872614591,2
--143744262(+) CTCTAC/GACCAG 1 -- ut310--------
rs94847441,2
C,F,A,H--143744264(+) CTAGAC/Tcaggg 1 -- ut3115Minor allele frequency- T:0.20NS EA NA WA 1908
rs93900901,2
C,F,A,H--143744326(+) gagtcG/Acatgg 1 -- ut3114Minor allele frequency- A:0.42NS EA NA WA CSA 785

HapMap Linkage Disequilibrium report for ADAT2 (143743969 - 143771841 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ADAT2: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ADAT2
DNA2.0 Custom Variant and Variant Library Synthesis for ADAT2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 615388    OMIM disorders: --


Find genes that share disorders with ADAT2           About GenesLikeMe


Export disorders for ADAT2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ADAT2 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with ADAT2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. RNA editing by adenosine deaminases generates RNA and protein diversity. (PubMed id 12457566)1, 2, 3 Schaub M. and Keller W. (Biochimie 2002)
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
  3. Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers. (PubMed id 20581866)1 Caron C....Khochbin S. (Oncogene 2010)
  4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (Nature 2003)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (Science 2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 134637 HGNC: 21172 AceView: DEADC1 Ensembl:ENSG00000189007 euGenes: HUgn134637
ECgene: ADAT2 H-InvDB: ADAT2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ADAT2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ADAT2 gene:
Search GeneIP for patents involving ADAT2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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