Aliases for ADAT1 Gene
External Ids for ADAT1 Gene
Previous GeneCards Identifiers for ADAT1 Gene
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
GeneCards Summary for ADAT1 Gene
ADAT1 (Adenosine Deaminase, TRNA-Specific 1) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA modification in the nucleus and cytosol. GO annotations related to this gene include RNA binding and tRNA-specific adenosine deaminase activity. An important paralog of this gene is ADARB2.
UniProtKB/Swiss-Prot for ADAT1 Gene
Specifically deaminates adenosine-37 to inosine in tRNA-Ala