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Aliases for ADAMTSL4-AS1 Gene

Subcategory (RNA class) for ADAMTSL4-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ADAMTSL4-AS1 Gene

  • ADAMTSL4 Antisense RNA 1 2 3 4 5
  • C1orf138 3 4
  • Chromosome 1 Open Reading Frame 138 2
  • ADAMTSL4 Antisense Gene Protein 1 4

External Ids for ADAMTSL4-AS1 Gene

Previous HGNC Symbols for ADAMTSL4-AS1 Gene

  • C1orf138

Previous GeneCards Identifiers for ADAMTSL4-AS1 Gene

  • GC01M150533

Summaries for ADAMTSL4-AS1 Gene

GeneCards Summary for ADAMTSL4-AS1 Gene

ADAMTSL4-AS1 (ADAMTSL4 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAMTSL4-AS1 Gene

Genomics for ADAMTSL4-AS1 Gene

Regulatory Elements for ADAMTSL4-AS1 Gene

Enhancers for ADAMTSL4-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G150514 1.2 ENCODE 12.2 +58.7 58738 2.7 CREB3L1 AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ADAMTSL4 SETDB1 GABPB2 MRPS21 PRPF3 LOC100289061 ADAMTSL4-AS1 GOLPH3L HIST2H2BD HIST2H2BC
GH01G150507 1.2 Ensembl ENCODE 11.6 +66.1 66083 2.3 HDGF SIN3A ARID4B GLIS2 FOS ZNF263 SP5 JUNB PPARG ZNF592 MRPS21 ADAMTSL4 VPS72 LOC100289061 ADAMTSL4-AS1 LYSMD1 GABPB2 CA14 VPS45 ECM1
GH01G150476 1 Ensembl ENCODE 11.5 +96.9 96867 2.2 HDAC1 LEF1 FOXA2 ZNF133 FEZF1 ZBTB7B ZKSCAN1 ZNF121 ZFHX2 MTA3 ECM1 MRPS21 ADAMTSL4 LOC100289061 ADAMTSL4-AS1 C1orf54 APH1A HORMAD1 PRUNE1 RNU6-884P
GH01G150472 0.9 ENCODE 11.5 +100.9 100924 1.6 ELF3 FOXA2 ATF1 ARID4B DNMT3B ZNF48 ZSCAN9 RAD21 RARA YY1 ADAMTSL4 ECM1 LOC100289061 ADAMTSL4-AS1 APH1A C1orf54 HORMAD1 PRUNE1 RNU6-884P TARS2
GH01G150484 0.9 Ensembl ENCODE 11.1 +89.7 89669 0.8 CTCF TAL1 REST RAD21 FOSL1 E2F1 ARID1B JUND SMARCA4 NCOR1 ECM1 ADAMTSL4 LOC100289061 ADAMTSL4-AS1 PRPF3 APH1A C1orf54 CA14 UBE2D3P3 CTSK
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ADAMTSL4-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ADAMTSL4-AS1 Gene

Chromosome:
1
Start:
150,560,202 bp from pter
End:
150,574,552 bp from pter
Size:
14,351 bases
Orientation:
Minus strand

Genomic View for ADAMTSL4-AS1 Gene

Genes around ADAMTSL4-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAMTSL4-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAMTSL4-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAMTSL4-AS1 Gene

Proteins for ADAMTSL4-AS1 Gene

  • Protein details for ADAMTSL4-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5F5-A4AS1_HUMAN
    Recommended name:
    Uncharacterized protein ADAMTSL4-AS1
    Protein Accession:
    Q5T5F5
    Secondary Accessions:
    • Q6ZS69

    Protein attributes for ADAMTSL4-AS1 Gene

    Size:
    129 amino acids
    Molecular mass:
    14090 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ADAMTSL4-AS1 Gene

Post-translational modifications for ADAMTSL4-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAMTSL4-AS1 Gene

Domains & Families for ADAMTSL4-AS1 Gene

Protein Domains for ADAMTSL4-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAMTSL4-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAMTSL4-AS1 Gene

Function for ADAMTSL4-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAMTSL4-AS1 Gene

Localization for ADAMTSL4-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADAMTSL4-AS1 gene
Compartment Confidence
extracellular 2
cytosol 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ADAMTSL4-AS1 Gene

Pathways & Interactions for ADAMTSL4-AS1 Gene

SuperPathways for ADAMTSL4-AS1 Gene

No Data Available

Interacting Proteins for ADAMTSL4-AS1 Gene

Gene Ontology (GO) - Biological Process for ADAMTSL4-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAMTSL4-AS1 Gene

Drugs & Compounds for ADAMTSL4-AS1 Gene

No Compound Related Data Available

Transcripts for ADAMTSL4-AS1 Gene

mRNA/cDNA for ADAMTSL4-AS1 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAMTSL4-AS1 Gene

No ASD Table

Relevant External Links for ADAMTSL4-AS1 Gene

GeneLoc Exon Structure for
ADAMTSL4-AS1
ECgene alternative splicing isoforms for
ADAMTSL4-AS1

Expression for ADAMTSL4-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADAMTSL4-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ADAMTSL4-AS1 Gene

This gene is overexpressed in Whole Blood (x19.6).

Evidence on tissue expression from TISSUES for ADAMTSL4-AS1 Gene

  • Nervous system(4.4)
genes like me logo Genes that share expression patterns with ADAMTSL4-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAMTSL4-AS1 Gene

Orthologs for ADAMTSL4-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ADAMTSL4-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ADAMTSL4-AS1 35
  • 97 (a)
OneToOne
Species where no ortholog for ADAMTSL4-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ADAMTSL4-AS1 Gene

ENSEMBL:
Gene Tree for ADAMTSL4-AS1 (if available)
TreeFam:
Gene Tree for ADAMTSL4-AS1 (if available)

Paralogs for ADAMTSL4-AS1 Gene

No data available for Paralogs for ADAMTSL4-AS1 Gene

Variants for ADAMTSL4-AS1 Gene

Sequence variations from dbSNP and Humsavar for ADAMTSL4-AS1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111660862 Likely benign 150,560,949(+) CTTCC(A/T)TGTCG nc-transcript-variant, downstream-variant-500B
rs114181942 Uncertain significance 150,560,491(+) AGAAG(C/G)ACAAG nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime
rs181259344 Uncertain significance 150,560,472(+) AAAGA(A/G)GTTAC nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime
rs35531650 Uncertain significance 150,560,832(+) CCGCT(A/C)CCCCA nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime
rs587633776 Uncertain significance 150,560,529(+) GGAAA(A/G)GAAAG nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ADAMTSL4-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3587506 CNV loss 21293372
nsv1006838 CNV gain 25217958
nsv527379 CNV loss 19592680

Variation tolerance for ADAMTSL4-AS1 Gene

Gene Damage Index Score: 1.41; 27.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ADAMTSL4-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAMTSL4-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADAMTSL4-AS1 Gene

Disorders for ADAMTSL4-AS1 Gene

Relevant External Links for ADAMTSL4-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADAMTSL4-AS1

No disorders were found for ADAMTSL4-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAMTSL4-AS1 Gene

Publications for ADAMTSL4-AS1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ADAMTSL4-AS1 Gene

Sources for ADAMTSL4-AS1 Gene

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