Aliases for ADAMTSL1 Gene
External Ids for ADAMTSL1 Gene
Previous HGNC Symbols for ADAMTSL1 Gene
Previous GeneCards Identifiers for ADAMTSL1 Gene
This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADAMTSL1 Gene
ADAMTSL1 (ADAMTS Like 1) is a Protein Coding gene. Diseases associated with ADAMTSL1 include Quebec Platelet Disorder and Malaria. Among its related pathways are O-glycosylation of TSR domain-containing proteins and Diseases of glycosylation. GO annotations related to this gene include peptidase activity and metallopeptidase activity. An important paralog of this gene is ADAMTSL3.