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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADAMTS19 Gene

protein-coding   GIFtS: 48
GCID: GC05P128824

ADAM metallopeptidase with thrombospondin type 1 motif,...

(Previous names: a disintegrin-like and metalloprotease (reprolysin type)...)
 Explore 3 diseases affiliated with
ADAMTS19 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ADAMTS19    

Aliases
for ADAMTS19 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 191 2     ADAM-TS 192 3
A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin
Type 1 Motif, 191 2
     A Disintegrin And Metalloproteinase With Thrombospondin Motifs 192
ADAM-TS192 3     EC 3.4.24.-3
ADAMTS-192 3     

External Ids:    HGNC: 171111   Entrez Gene: 1710192   Ensembl: ENSG000001458087   OMIM: 6075135   UniProtKB: Q8TE593   

Export aliases for ADAMTS19 gene to outside databases

Previous GC identifers: GC05P128337 GC05P129231 GC05P128826 GC05P128872 GC05P123989


Summaries
for ADAMTS19 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ADAMTS19:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein
family. Members of the family share several distinct protein modules, including a propeptide region, a
metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of
this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded
by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. (provided by
RefSeq, Jul 2008)




Genomic Views
for ADAMTS19 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ADAMTS19 gene promoter:
         E2F-3a   E2F-4   E2F-5   AML1a   E2F-2   RORalpha1   FOXC1   E2F   E2F-1   HFH-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ADAMTS19 promoter sequence
   Search SABiosciences Chromatin IP Primers for ADAMTS19

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADAMTS19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q23.3   Ensembl cytogenetic band:  5q23.3   HGNC cytogenetic band: 5q23.3

ADAMTS19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADAMTS19 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P128824:  view genomic region     (about GC identifiers)

Start:
 128,795,958 bp from pter      End:
 129,074,376 bp from pter
Size:
 278,419 bases      Orientation:
 plus strand

Proteins
for ADAMTS19 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ATS19_HUMAN, Q8TE59 (See protein sequence)
Recommended Name: A disintegrin and metalloproteinase with thrombospondin motifs 19 precursor  
Size: 1207 amino acids; 134048 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)

Explore the universe of human proteins at neXtProt for ADAMTS19: NX_Q8TE59

Post-translational modifications:

  • The precursor is cleaved by a furin endopeptidase (By similarity)1
  • Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence
    • C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the
    repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose
    residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members.
    Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence
    W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TE59

    • ADAMTS19 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_598377.3  
    ENSEMBL proteins: 
     ENSP00000274487   ENSP00000423537   ENSP00000422491  

    Human Recombinant Protein Products: 
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    Uscn Proteins for ADAMTS19

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--


    ADAMTS19 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ADAMTS19

    Protein Domains /
    Families
    for ADAMTS19 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ADAMTS19 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR000884 Thrombospondin_1_rpt
     IPR024079 MetalloPept_cat_dom
     IPR010294 ADAM_spacer1
     IPR010909 PLAC
     IPR001590 Peptidase_M12B

    Graphical View of Domain Structure for InterPro Entry Q8TE59

    ProtoNet protein and cluster: Q8TE59

    4 Blocks protein families:
    IPB000884 Thrombospondin
    IPB001762 Disintegrin
    IPB002870 Metalloendopeptidase M12B
    IPB010294 ADAM-TS Spacer 1


    UniProtKB/Swiss-Prot: ATS19_HUMAN, Q8TE59
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the
    enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme
    Similarity: Contains 1 disintegrin domain
    Similarity: Contains 1 peptidase M12B domain
    Similarity: Contains 1 PLAC domain
    Similarity: Contains 5 TSP type-1 domains


    Function
    for ADAMTS19 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Enzyme Number (IUBMB): EC 3.4.24.-1

    miRNA
    Products:            		 OriGene 3'-UTR Clone: ADAMTS19
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ADAMTS19
    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate ADAMTS19 (see all 59):
    hsa-miR-411* hsa-miR-124* hsa-miR-3685 hsa-miR-3194-5p hsa-miR-379* hsa-miR-3146 hsa-miR-29a hsa-miR-301a
    SwitchGear 3'UTR luciferase reporter plasmid: ADAMTS19 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADAMTS19 (see all 7)
    OriGene shRNA RFP: ADAMTS19
    OriGene siRNA: ADAMTS19
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADAMTS19

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ADAMTS19

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADAMTS19 (see all 3)
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    GenScript: all cDNA clones in your preferred vector: ADAMTS19 (NM_133638)
    Browse Sino Biological Human cDNA Clones
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    Cell Line
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    Search LifeMap BioReagents cell lines for ADAMTS19

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004222metalloendopeptidase activity IEA--
    GO:0008270zinc ion binding IEA--


    ADAMTS19 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ADAMTS19 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADAMTS19

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--


    ADAMTS19 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ADAMTS19 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ADAMTS19
    Search CenterWatch for drugs/clinical trials and news about ADAMTS19 / ATS19 

    Transcripts
    for ADAMTS19 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ADAMTS19 gene: 
    NM_133638.3  

    Unigene Cluster for ADAMTS19:

    ADAM metallopeptidase with thrombospondin type 1 motif, 19
    Hs.23751  [show with all ESTs]
    Unigene Representative Sequence: NM_133638
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274487(uc003kvb.1 uc003kvc.1 uc010jdh.1) ENST00000505791
    ENST00000502709 ENST00000509467

    miRNA
    Products:             		 OriGene 3'-UTR Clone: ADAMTS19
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ADAMTS19
    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate ADAMTS19 (see all 59):
    hsa-miR-411* hsa-miR-124* hsa-miR-3685 hsa-miR-3194-5p hsa-miR-379* hsa-miR-3146 hsa-miR-29a hsa-miR-301a
    SwitchGear 3'UTR luciferase reporter plasmid: ADAMTS19 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADAMTS19 (see all 7)
    OriGene shRNA RFP: ADAMTS19
    OriGene siRNA: ADAMTS19
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADAMTS19
    Clone
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    GenScript: all cDNA clones in your preferred vector: ADAMTS19 (NM_133638)
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    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ADAMTS19
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADAMTS19
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADAMTS19

    Additional cDNA sequence: 

    AJ311904.1 AK122622.1 AK128729.1 

    2 DOTS entries:

    DT.75153159  DT.100674509 

    8 AceView cDNA sequences:

    BV174619 AL523577 NM_133638 AJ311904 AK128729 AK122622 CR597547 BX371368 

    GeneLoc Exon Structure


    Expression
    for ADAMTS19 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ADAMTS19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCACCCTTTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ADAMTS19 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartAtrioventricular CanalAtrioventricular Canal CellsMyocardium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Primitive gut tube-like cells (A scalable, suspensi...)

    See ADAMTS19 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ADAMTS19

    SOURCE GeneReport for Unigene cluster: Hs.23751

    UniProtKB/Swiss-Prot: ATS19_HUMAN, Q8TE59
    Tissue specificity: Expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an
    osteosarcoma cDNA library

        SABiosciences Custom PCR Arrays for ADAMTS19
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS19

    Orthologs
    for ADAMTS19 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for ADAMTS19 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ADAMTS191 ADAM metallopeptidase with thrombospondin type 1 motif, more 78.6(n)
    82.4(a)    		   415600  XM_413968.3  XP_413968.3 
    lizard
    (Anolis carolinensis)    		 Reptilia ADAMTS196
    		 --
    		 77(a)
    		 1 ↔ 1
    		 2(30600349-30738905)
    zebrafish
    (Danio rerio)    		 Actinopterygii CABZ01112436.16
    		 --
    		 6(a)
    		 possible ortholog
    		 Zv9_NA786(408-22627)
    worm
    (Caenorhabditis elegans)    		 Secernentea mig-176
    		 ADAM family mig-17
    		 14(a)
    		 possible ortholog
    		 V(11446634-11449228)


    ENSEMBL Gene Tree for ADAMTS19 (if available)
    TreeFam Gene Tree for ADAMTS19 (if available) 

    Paralogs
    for ADAMTS19 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ADAMTS19 gene
    ADAMTS172  ADAMTS182  ADAMTS62  ADAMTS122  ADAMTS202  ADAMTS52  ADAMTS42  ADAMTS92  
    ADAMTS162  ADAMTS102  ADAMTS72  ADAMTS12  ADAMTS142  ADAMTS22  ADAMTS152  ADAMTS82  
    ADAMTS32  
    3 SIMAP similar genes for ADAMTS19 using alignment to 3 protein entries:     ATS19_HUMAN (see all proteins):
    ADAMTS17    ADAMTS13    ADAMTS18

    ADAMTS19 for paralogs           About GeneDecksing



    Genomic Variants
    for ADAMTS19 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4858 NCBI SNPs in ADAMTS19 are shown (see all 4858)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs45417011,2
    		C,F,--128794283(+) TTACTC/ACAGCA 1 -- us2k16Minor allele frequency- A:0.26WA CSA NA 246
    rs1859442311,2
    		--128794309(+) GACAGA/C/GGTTTA 1 -- us2k10--------
    rs38531281,2
    		C,F,A,H,--128794337(-) GGTGAC/GTTTGT 1 -- us2k115Minor allele frequency- G:0.41NS EA WA CSA NA 1204
    rs1907141451,2
    		--128794448(+) TCTGCC/TTCCCT 1 -- us2k10--------
    rs772140281,2
    		--128794537(+) GGAATA/TAAAAA 1 -- us2k10--------
    rs732404581,2
    		C,F,--128794538(+) GAATTA/TAAAAA 1 -- us2k11Minor allele frequency- T:0.08WA 118
    rs1833861461,2
    		--128794607(+) GCAAAC/TGGCAG 1 -- us2k10--------
    rs38531291,2
    		C,F,H,--128794658(-) CCTCAG/TCCACA 1 -- us2k16Minor allele frequency- T:0.01NS NA 928
    rs1400383351,2
    		--128794721(+) AAAAAA/TATATA 1 -- us2k10--------
    rs48359741,2
    		C,F,H,--128794782(+) TATGTA/GCAAGT 1 -- us2k13Minor allele frequency- G:0.03NS NA 230

    HapMap Linkage Disequilibrium report for ADAMTS19 (128795958 - 129045958 bp, first 250kb of ADAMTS19)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for ADAMTS19
         4 CNVs: 3574 64305 4478 8498
         3 Indels: 81039 93231 93230

    3 SABiosciences Cancer Mutation PCR Assays for ADAMTS19:
    Cosmic IdAA Change
    138506p.R969*
    27204p.L360I
    108171p.R969Q
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADAMTS19
    DNA2.0 Custom Variant and Variant Library Synthesis for ADAMTS19

    Disorders / Diseases
    for ADAMTS19 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ADAMTS19 for disorders           About GeneDecksing

    OMIM gene information: 607513    OMIM disorders: --

    3 diseases for ADAMTS19:    About MalaCards
    premature ovarian failure    hermaphroditism    osteosarcoma

    1 disease from the University of Copenhagen DISEASES database for ADAMTS19:
    Premature ovarian failure
    Human Genome Epidemiology (HuGE) Navigator: ADAMTS19 (1 document)

    Export disorders for ADAMTS19 gene to outside databases

    Publications
    for ADAMTS19 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ADAMTS19 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ADAMTS19)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. (PubMed id 11867212)1, 2, 3 Cal S....Lopez-Otin C. (2002)
    2. Genome-wide association study of SSRI/SNRI-induced sex ual dysfunction in a Japanese cohort with major depression. (PubMed id 22445761)1 Kurose K....Saito Y. (2012)
    3. Genome-wide association study in premature ovarian fa ilure patients suggests ADAMTS19 as a possible candidate gene. (PubMed id 19508998)1 Knauff E.A....Fauser B.C. (2009)
    4. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    5. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)

    External Searches for ADAMTS19 gene

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    Genome Databases showing ADAMTS19 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 171019 HGNC: 17111 AceView: ADAMTS19 Ensembl:ENSG00000145808 euGenes: HUgn171019
    ECgene: ADAMTS19 H-InvDB: ADAMTS19

    Other Databases showing ADAMTS19 gene

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    Specialized Databases showing ADAMTS19 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    PharmGKB entry for ADAMTS19 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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