Aliases for ADAMTS17 Gene
External Ids for ADAMTS17 Gene
Previous GeneCards Identifiers for ADAMTS17 Gene
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADAMTS17 Gene
ADAMTS17 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 17) is a Protein Coding gene. Diseases associated with ADAMTS17 include ichthyosis-short stature-brachydactyly-microspherophakia syndrome and weill-marchesani-like syndrome. Among its related pathways are Transport to the Golgi and subsequent modification and O-linked glycosylation. GO annotations related to this gene include peptidase activity and metalloendopeptidase activity. An important paralog of this gene is ADAMTS16.