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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADAMTS16 Gene

protein-coding   GIFtS: 50
GCID: GC05P005140

ADAM Metallopeptidase With Thrombospondin Type 1 Motif,...

(Previous names: a disintegrin-like and metalloprotease (reprolysin type)...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 161 2     ADAMTS16s2
A Disintegrin-Like And Metalloprotease (Reprolysin Type) With
Thrombospondin Type 1 Motif, 161 2
     A Disintegrin And Metalloproteinase With Thrombospondin Motifs 162
ADAM-TS162 3     EC 3.4.24.-3
ADAMTS-162 3     KIAA20293
ADAM-TS 162 3     

External Ids:    HGNC: 171081   Entrez Gene: 1706902   Ensembl: ENSG000001455367   OMIM: 6075105   UniProtKB: Q8TE573   

Export aliases for ADAMTS16 gene to outside databases

Previous GC identifers: GC05P005281 GC05P005173 GC05P005193 GC05P005113


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ADAMTS16 Gene:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein
family. ADAMTS family members share several distinct protein modules, including a propeptide region, a
metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members
of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein
encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ADAMTS16 Gene: 
ADAMTS16 (ADAM metallopeptidase with thrombospondin type 1 motif, 16) is a protein-coding gene. Diseases associated with ADAMTS16 include hypertension, and prostatitis. GO annotations related to this gene include metalloendopeptidase activity and zinc ion binding. An important paralog of this gene is ADAMTS17.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ADAMTS16 gene promoter:
         AML1a   NCX/Ncx   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Cdc5   Nkx5-1   E47   RORalpha1   Pax-3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidADAMTS16 promoter sequence
   Search SABiosciences Chromatin IP Primers for ADAMTS16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADAMTS16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15   Ensembl cytogenetic band:  5p15.32   HGNC cytogenetic band: 5p15

ADAMTS16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADAMTS16 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P005140:  view genomic region     (about GC identifiers)

Start:
5,140,443 bp from pter      End:
5,320,417 bp from pter
Size:
179,975 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57 (See protein sequence)
Recommended Name: A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor  
Size: 1224 amino acids; 136203 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: C6G490 Q8IVE2
Alternative splicing: 2 isoforms:  Q8TE57-1   Q8TE57-2   

Explore the universe of human proteins at neXtProt for ADAMTS16: NX_Q8TE57

Explore proteomics data for ADAMTS16 at MOPED 

Post-translational modifications:

  • UniProtKB: The precursor is cleaved by a furin endopeptidase (By similarity)
  • UniProtKB: Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus
    sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine
    residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a
    beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of
    ADAMTS family members. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within
    the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate
    secretion (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TE57

  • ADAMTS16 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ADAMTS16 Protein Expression
    REFSEQ proteins: NP_620687.2  
    ENSEMBL proteins: 
     ENSP00000421631   ENSP00000274181  

    Human Recombinant Protein Products for ADAMTS16: 
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    Cloud-Clone Corp. Proteins for ADAMTS16 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0031012extracellular matrix ----

    ADAMTS16 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ADAMTS: ADAM metallopeptidases with thrombospondin type 1 motif

    IUPHAR Guide to PHARMACOLOGY protein family classification: ADAMTS16 
    ADAMTS family

    5/7 InterPro protein domains (see all 7):
     IPR000884 Thrombospondin_1_rpt
     IPR024079 MetalloPept_cat_dom
     IPR010294 ADAM_spacer1
     IPR010909 PLAC
     IPR001590 Peptidase_M12B

    Graphical View of Domain Structure for InterPro Entry Q8TE57

    ProtoNet protein and cluster: Q8TE57

    5 Blocks protein domains:
    IPB000884 Thrombospondin
    IPB001762 Disintegrin
    IPB002870 Metalloendopeptidase M12B
    IPB008085 Thrombospondin type 1 repeat signature
    IPB010294 ADAM-TS Spacer 1


    UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57
    Domain: The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular
    matrix (By similarity)
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting
    the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the
    enzyme
    Similarity: Contains 1 disintegrin domain
    Similarity: Contains 1 peptidase M12B domain
    Similarity: Contains 1 PLAC domain
    Similarity: Contains 6 TSP type-1 domains


    ADAMTS16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Number (IUBMB): EC 3.4.24.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004222metalloendopeptidase activity IEA--
    GO:0008233peptidase activity ----
    GO:0008270zinc ion binding IEA--
         
    ADAMTS16 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidADAMTS16 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS16


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADAMTS16

    1 Interacting protein for ADAMTS16 (Q8TE573) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAEAQ7L5Y93I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--

    ADAMTS16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ADAMTS16 (ATS16)

    Search CenterWatch for drugs/clinical trials and news about ADAMTS16 / ATS16

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ADAMTS16 gene: 
    NM_139056.2  

    Unigene Cluster for ADAMTS16:

    ADAM metallopeptidase with thrombospondin type 1 motif, 16
    Hs.661915  [show with all ESTs]
    Unigene Representative Sequence: NM_139056
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000511368(uc003jdj.1) ENST00000274181(uc003jdk.1 uc003jdl.3)
    ENST00000433402(uc010itk.1) ENST00000513709
    miRNA
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    hsa-miR-3163 hsa-miR-548a-3p hsa-miR-4291 hsa-miR-548e hsa-miR-545 hsa-miR-340 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmidADAMTS16 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB095949.1 AK122980.1 AK127746.1 AM983533.1 DQ266047.1 

    4 DOTS entries:

    DT.435993  DT.97836751  DT.70102829  DT.101977476 

    24/32 AceView cDNA sequences (see all 32):

    AI969349 AB095949 BM845044 BM845406 BM850160 BX112729 NM_139056 AW236577 
    BM906555 CD636683 AI823432 AA341442 AI740544 AK122980 CD636677 AJ315734 
    BE645050 AA716087 BM808410 CD636673 CD636675 CD636681 AK127746 AI743336 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ADAMTS16 expression in normal human tissues (normalized intensities)      ADAMTS16 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ADAMTS16 Expression
    About this image


    ADAMTS16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Mesencephalic Ventricular Zone
             spinal cord/lateral wall/ventricular layer   
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Testis (Reproductive System)
             Pre-Sertoli Cells Testis Cord
     
     Kidney (Urinary System)
             visceral organ/metanephros/calyx   
     
     Lower Urinary Tract (Urinary System)
             visceral organ/metanephros/calyx   

    See ADAMTS16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ADAMTS16

    SOURCE GeneReport for Unigene cluster: Hs.661915

    UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57
    Tissue specificity: Expressed in fetal lung and kidney and in adult prostate and ovary

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ADAMTS16 gene from 3/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Adamts161 , 5 a disintegrin-like and metallopeptidase (reprolysin more1, 5 81.67(n)1
    83.21(a)1
      13 (35.97 cM)5
    2711271  NM_172053.21  NP_742050.21 
     707278025 
    lizard
    (Anolis carolinensis)
    Reptilia ADAMTS166
    ADAM metallopeptidase with thrombospondin type 1 m...
    70(a)
    1 ↔ 1
    GL343211.1(2837912-2956975)
    zebrafish
    (Danio rerio)
    Actinopterygii adamts161 ADAM metallopeptidase with thrombospondin type 1 motif, more 65.12(n)
    64.21(a)
      568792  XM_001922411.3  XP_001922446.3 


    ENSEMBL Gene Tree for ADAMTS16 (if available)
    TreeFam Gene Tree for ADAMTS16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ADAMTS16 gene
    ADAMTS172  ADAMTS12  ADAMTS182  ADAMTS192  ADAMTS62  ADAMTS142  ADAMTS22  ADAMTS202  
    ADAMTS52  ADAMTS152  ADAMTS42  ADAMTS92  ADAMTS82  ADAMTS32  ADAMTS102  
    15 SIMAP similar genes for ADAMTS16 using alignment to 4 protein entries:     ATS16_HUMAN (see all proteins):
    ADAMTS18    PAPLN    ADAMTSL4    ADAMTSL1    ADAMTS12    ADAMTS6
    ADAMTS7    ADAMTSL5    ADAMTS10    DKFZp434K1772    ADAMTS1    DKFZp686E01144
    ADAMTS9    ADAMTS20    ADAMTS4

    ADAMTS16 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4496 SNPs in ADAMTS16 are shown (see all 4496)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1877429041,2
    C--5138466(+) CAATCA/C/GATACT 1 -- us2k10--------
    rs1926057931,2
    --5138468(+) ATCGAC/TACTCT 1 -- us2k10--------
    rs1835699061,2
    --5138542(+) ATCTGA/GTGGGG 1 -- us2k10--------
    rs2702141,2
    C,A,H--5138580(-) tttacA/Catccc 1 -- us2k12Minor allele frequency- C:0.38NA NS 190
    rs111340931,2
    C,F,A,H--5138741(+) ttttgC/Tttttt 1 -- us2k12Minor allele frequency- T:0.50NA 4
    rs709659241,2
    C--5138773(+) TTTTT-/T/TTTT
            
    GAGAC
    1 -- us2k12NA 4
    rs131748871,2
    C,F--5138866(+) agctcC/Tgcctc 1 -- us2k13Minor allele frequency- T:0.50NA 6
    rs1112387581,2
    C--5138881(+) GTTCAC/TGCCAT 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1999776311,2
    C--5138926(+) CAGGCA/GCCCGC 1 -- us2k10--------
    rs2702131,2
    C--5138943(-) attagA/Ccgggc 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ADAMTS16 (5140443 - 5320417 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for ADAMTS16 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2729674CNV Deletion23290073
    esv2729671CNV Deletion23290073
    esv2729670CNV Deletion23290073
    esv2729672CNV Deletion23290073
    nsv4691CNV Insertion18451855
    esv269786CNV Insertion20981092
    nsv526817CNV Loss19592680
    esv25455CNV Loss19812545
    esv5491CNV Loss19470904
    nsv830194CNV Gain17160897


    Human Gene Mutation Database (HGMD): ADAMTS16
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607510    OMIM disorders: --

    2 diseases for ADAMTS16:    About MalaCards
    hypertension    prostatitis


    ADAMTS16 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ADAMTS16
    Human Genome Epidemiology (HuGE) Navigator: ADAMTS16 (1 document)

    Export disorders for ADAMTS16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ADAMTS16 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with ADAMTS16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. (PubMed id 11867212)1, 2, 3 Cal S....Lopez-Otin C. (2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Characterization and regulation of ADAMTS-16. (PubMed id 19635554)1, 9 Surridge A.K....Clark I.M. (2009)
    4. Positional identification of variants of Adamts16 lin ked to inherited hypertension. (PubMed id 19423552)1, 9 Joe B....Bouchard C. (2009)
    5. Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchyma l stem cells. (PubMed id 22562232)1 Boeuf S....Richter W. (2012)
    6. A genome-wide association study identifies a novel ma jor locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PubMed id 19875614)4 Paterson A.D....Bull S.B. (2010)
    7. A genome-wide association study of sporadic ALS in a homogenous Irish population. (PubMed id 18057069)4 Cronin S....Hardiman O. (2008)
    8. FSH stimulates the expression of the ADAMTS-16 protease in mature human ovarian follicles. (PubMed id 17519324)1 Gao S.... Zhang H. (2007)
    9. Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. (PubMed id 16507336)1 Zeng W....Flannery C.R. (2006)
    10. High-resolution whole-genome association study of Parkinson disease. (PubMed id 16252231)4 Maraganore D.M....Ballinger D.G. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 170690 HGNC: 17108 AceView: ADAMTS16 Ensembl:ENSG00000145536 euGenes: HUgn170690
    ECgene: ADAMTS16 H-InvDB: ADAMTS16

    (According to HUGE)
    About This Section
    HUGE: KIAA2029

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ADAMTS16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ADAMTS16 gene:
    Search GeneIP for patents involving ADAMTS16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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