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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ADAMTS16 Gene

protein-coding   GIFtS: 49
GCID: GC05P005140

ADAM metallopeptidase with thrombospondin type 1 motif,...

(Previous names: a disintegrin-like and metalloprotease (reprolysin type)...)
 Explore 2 diseases affiliated with
ADAMTS16 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ADAMTS16    

Aliases
for ADAMTS16 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 161 2     ADAM-TS 162 3
ADAMTS16s1 2     A Disintegrin And Metalloproteinase With Thrombospondin Motifs 162
A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin
Type 1 Motif, 161 2
     EC 3.4.24.-3
ADAM-TS162 3     KIAA20293
ADAMTS-162 3     

External Ids:    HGNC: 171081   Entrez Gene: 1706902   Ensembl: ENSG000001455367   OMIM: 6075105   UniProtKB: Q8TE573   

Export aliases for ADAMTS16 gene to outside databases

Previous GC identifers: GC05P005281 GC05P005173 GC05P005193 GC05P005113


Summaries
for ADAMTS16 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ADAMTS16:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein
family. ADAMTS family members share several distinct protein modules, including a propeptide region, a
metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of
this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded
by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member. (provided by
RefSeq, Jul 2008)




Genomic Views
for ADAMTS16 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ADAMTS16 gene promoter:
         AML1a   NCX/Ncx   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Cdc5   Nkx5-1   E47   RORalpha1   Pax-3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ADAMTS16 promoter sequence
   Search SABiosciences Chromatin IP Primers for ADAMTS16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADAMTS16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15   Ensembl cytogenetic band:  5p15.32   HGNC cytogenetic band: 5p15

ADAMTS16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ADAMTS16 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P005140:  view genomic region     (about GC identifiers)

Start:
 5,140,443 bp from pter      End:
 5,320,417 bp from pter
Size:
 179,975 bases      Orientation:
 plus strand

Proteins
for ADAMTS16 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57 (See protein sequence)
Recommended Name: A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor  
Size: 1224 amino acids; 136203 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: C6G490 Q8IVE2
Alternative splicing: 2 isoforms:  Q8TE57-1   Q8TE57-2   

Explore the universe of human proteins at neXtProt for ADAMTS16: NX_Q8TE57

Post-translational modifications:

  • The precursor is cleaved by a furin endopeptidase (By similarity)1
  • Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence
    • C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the
    repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose
    residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members.
    Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence
    W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TE57

    • ADAMTS16 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_620687.2  
    ENSEMBL proteins: 
     ENSP00000421631   ENSP00000274181  

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    Uscn Proteins for ADAMTS16

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005578proteinaceous extracellular matrix IEA--


    ADAMTS16 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ADAMTS16

    Protein Domains /
    Families
    for ADAMTS16 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ADAMTS16 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR000884 Thrombospondin_1_rpt
     IPR024079 MetalloPept_cat_dom
     IPR010294 ADAM_spacer1
     IPR010909 PLAC
     IPR001590 Peptidase_M12B

    Graphical View of Domain Structure for InterPro Entry Q8TE57

    ProtoNet protein and cluster: Q8TE57

    5 Blocks protein families:
    IPB000884 Thrombospondin
    IPB001762 Disintegrin
    IPB002870 Metalloendopeptidase M12B
    IPB008085 Thrombospondin type 1 repeat signature
    IPB010294 ADAM-TS Spacer 1


    UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57
    Domain: The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular
    matrix (By similarity)
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the
    enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme
    Similarity: Contains 1 disintegrin domain
    Similarity: Contains 1 peptidase M12B domain
    Similarity: Contains 1 PLAC domain
    Similarity: Contains 6 TSP type-1 domains


    Function
    for ADAMTS16 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Enzyme Number (IUBMB): EC 3.4.24.-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ADAMTS16
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ADAMTS16:
    hsa-miR-3163 hsa-miR-548a-3p hsa-miR-4291 hsa-miR-548e hsa-miR-545 hsa-miR-340 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmid: ADAMTS16 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: ADAMTS16
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADAMTS16 (see all 3)
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004222metalloendopeptidase activity IEA--
    GO:0008270zinc ion binding IEA--


    ADAMTS16 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ADAMTS16 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADAMTS16

    1 Interacting protein for ADAMTS16 (Q8TE573) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAEAQ7L5Y93I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--


    ADAMTS16 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ADAMTS16 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ADAMTS16
    Search CenterWatch for drugs/clinical trials and news about ADAMTS16 / ATS16 

    Transcripts
    for ADAMTS16 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ADAMTS16 gene: 
    NM_139056.2  

    Unigene Cluster for ADAMTS16:

    ADAM metallopeptidase with thrombospondin type 1 motif, 16
    Hs.661915  [show with all ESTs]
    Unigene Representative Sequence: NM_139056
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000511368(uc003jdj.1) ENST00000274181(uc003jdk.1 uc003jdl.3)
    ENST00000433402(uc010itk.1) ENST00000513709

    miRNA
    Products:             		 OriGene 3'-UTR Clone: ADAMTS16
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ADAMTS16:
    hsa-miR-3163 hsa-miR-548a-3p hsa-miR-4291 hsa-miR-548e hsa-miR-545 hsa-miR-340 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmid: ADAMTS16 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADAMTS16 (see all 7)
    OriGene shRNA RFP: ADAMTS16
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADAMTS16
    Clone
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    Primer
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    Additional cDNA sequence: 

    AB095949.1 AK122980.1 AK127746.1 AM983533.1 DQ266047.1 

    4 DOTS entries:

    DT.435993  DT.97836751  DT.70102829  DT.101977476 

    24/32 AceView cDNA sequences (see all 32):

    BX112729 BM850160 BM845044 AI969349 AB095949 AW236577 NM_139056 BM845406 
    CD636677 AA341442 AK122980 CD636673 AA716087 BE645050 BM808410 AI823432 
    CD636683 AI743336 BQ774377 BM844919 AI740544 AJ315734 AK127746 CD636681 

    GeneLoc Exon Structure


    Expression
    for ADAMTS16 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ADAMTS16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ADAMTS16 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbForelimb MyotomeLimb Muscle Progenitor CellsSkeletal Muscle
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Cartilage-like cells (Differentiation of s...)Cartilage

    See ADAMTS16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ADAMTS16

    SOURCE GeneReport for Unigene cluster: Hs.661915

    UniProtKB/Swiss-Prot: ATS16_HUMAN, Q8TE57
    Tissue specificity: Expressed in fetal lung and kidney and in adult prostate and ovary

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    In Situ
    Assay Products:     
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    Orthologs
    for ADAMTS16 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for ADAMTS16 gene from 2/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia ADAMTS166
    		 --
    		 72(a)
    		 1 ↔ 1
    		 GL343211.1(2840613-2931055)
    zebrafish
    (Danio rerio)    		 Actinopterygii adamts161 ADAM metallopeptidase with thrombospondin type 1 motif, more 65.12(n)
    64.21(a)    		   568792  XM_001922411.3  XP_001922446.3 


    ENSEMBL Gene Tree for ADAMTS16 (if available)
    TreeFam Gene Tree for ADAMTS16 (if available) 

    Paralogs
    for ADAMTS16 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ADAMTS16 gene
    ADAMTS72  ADAMTS172  ADAMTS12  ADAMTS182  ADAMTS192  ADAMTS62  ADAMTS122  ADAMTS142  
    ADAMTS22  ADAMTS202  ADAMTS52  ADAMTS42  ADAMTS152  ADAMTS82  ADAMTS92  ADAMTS32  
    ADAMTS102  
    15 SIMAP similar genes for ADAMTS16 using alignment to 4 protein entries:     ATS16_HUMAN (see all proteins):
    ADAMTS18    PAPLN    ADAMTSL4    ADAMTSL1    ADAMTS12    ADAMTS6
    ADAMTS7    ADAMTSL5    ADAMTS10    DKFZp434K1772    ADAMTS1    DKFZp686E01144
    ADAMTS9    ADAMTS20    ADAMTS4

    ADAMTS16 for paralogs           About GeneDecksing



    Genomic Variants
    for ADAMTS16 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3852 NCBI SNPs in ADAMTS16 are shown (see all 3852)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1877429041,2
    		--5138466(+) CAATCA/GATACT 1 -- us2k10--------
    rs1926057931,2
    		--5138468(+) ATCGAC/TACTCT 1 -- us2k10--------
    rs1835699061,2
    		--5138542(+) ATCTGA/GTGGGG 1 -- us2k10--------
    rs2702141,2
    		C,A,H,--5138580(-) TTTACA/CATCCC 1 -- us2k12Minor allele frequency- C:0.38NA NS 190
    rs111340931,2
    		C,F,A,H,--5138741(+) TTTTGC/TTTTTT 1 -- us2k12Minor allele frequency- T:0.50NA 4
    rs131748871,2
    		C,F,--5138866(+) AGCTCC/TGCCTC 1 -- us2k13Minor allele frequency- T:0.50NA 6
    rs2702131,2
    		--5138943(-) attagA/Ccgggc 1 -- us2k10--------
    rs1923455401,2
    		--5139022(+) TGATCC/TGCCCG 1 -- us2k10--------
    rs1121779701,2
    		C,--5139023(+) GATCCG/ACCCGC 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1127252701,2
    		--5139032(+) GCCTCA/GGCCTC 1 -- us2k11Minor allele frequency- G:0.00CSA 1

    HapMap Linkage Disequilibrium report for ADAMTS16 (5140443 - 5320417 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 12 variations for ADAMTS16
         10 CNVs: 80807 92858 80808 3539 92855 92857 80806 92854 92856 80809
         2 Indels: 62341 68996
    Human Gene Mutation Database (HGMD): ADAMTS16

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADAMTS16
    DNA2.0 Custom Variant and Variant Library Synthesis for ADAMTS16

    Disorders / Diseases
    for ADAMTS16 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ADAMTS16 for disorders           About GeneDecksing

    OMIM gene information: 607510    OMIM disorders: --

    2 diseases for ADAMTS16:    About MalaCards
    hypertension    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: ADAMTS16 (1 document)

    Export disorders for ADAMTS16 gene to outside databases

    Publications
    for ADAMTS16 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ADAMTS16 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ADAMTS16)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. (PubMed id 11867212)1, 2, 3 Cal S....Lopez-Otin C. (2002)
    2. Characterization and regulation of ADAMTS-16. (PubMed id 19635554)1, 9 Surridge A.K....Clark I.M. (2009)
    3. Positional identification of variants of Adamts16 lin ked to inherited hypertension. (PubMed id 19423552)1, 9 Joe B....Bouchard C. (2009)
    4. Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchyma l stem cells. (PubMed id 22562232)1 Boeuf S....Richter W. (2012)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    6. FSH stimulates the expression of the ADAMTS-16 protease in mature human ovarian follicles. (PubMed id 17519324)1 Gao S.... Zhang H. (2007)
    7. Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. (PubMed id 16507336)1 Zeng W....Flannery C.R. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)

    External Searches for ADAMTS16 gene

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    Genome Databases showing ADAMTS16 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 170690 HGNC: 17108 AceView: ADAMTS16 Ensembl:ENSG00000145536 euGenes: HUgn170690
    ECgene: ADAMTS16 H-InvDB: ADAMTS16

    Other Databases showing ADAMTS16 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA2029

    Specialized Databases showing ADAMTS16 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ADAMTS16 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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