ADAMTS15 Gene
protein-coding GIFtS : 47
GCID: GC11 P130318
ADAM metallopeptidase with thrombospondin type 1 motif,... (Previous names: a disintegrin-like and metalloprotease (reprolysin type)... )
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Aliasesfor ADAMTS15 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 15 1 2 A Disintegrin-Like And Metalloprotease (Reprolysin Type) With ThrombospondinType 1 Motif, 15, Preproprotein2 ADAM-TS152 3 Metalloprotease Disintegrin 15 With Thrombospondin Domains2 ADAMTS-152 3 EC 3.4.24.-3 ADAM-TS 152 3 EC 3.4.248 A Disintegrin-Like And Metalloprotease (Reprolysin Type) With ThrombospondinType 1 Motif, 151 EC 3.4.24.148 A Disintegrin And Metalloproteinase With Thrombospondin Motifs 152 EC 3.4.24.828
Export aliases for ADAMTS15 gene to outside databases Previous GC identifers: GC11P132319 GC11P131831 GC11P130352 GC11P129856 GC11P129824 GC11P126273
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Summariesfor ADAMTS15 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ADAMTS15 : This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the proteins encoded by ADAMTS1 and ADAMTS8. (provided by RefSeq, Jul 2008)
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Genomic Viewsfor ADAMTS15 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000011.9 NC_018922.1 NT_033899.8 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ADAMTS15 gene promoter: ER-alpha STAT1 STAT1beta FOXO3 Lmo2 STAT1alpha FOXO3b FOXL1 FOXO3a ZID Other transcription factors Search SABiosciences Chromatin IP Primers for ADAMTS15 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ADAMTS15
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 11q25 Ensembl cytogenetic band: 11q24.3 HGNC cytogenetic band: 11q25 ADAMTS15 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11P130318: view genomic region
(about GC identifiers )
Start:
130,318,869 bp from pter
End:
130,346,539 bp from pter
Size:
27,671 bases
Orientation:
plus strand
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Proteinsfor ADAMTS15 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ATS15_HUMAN, Q8TE58 (See
protein sequence )Recommended Name: A disintegrin and metalloproteinase with thrombospondin motifs 15 precursor Size : 950 amino acids; 103287 Da
Cofactor : Binds 1 zinc ion per subunit (By similarity)
Subcellular location : Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions : Q32MI6Explore the universe of human proteins at neXtProt for ADAMTS15: NX_Q8TE58 Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity)1
Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity)1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8TE58 4/10 DME Specific Peptides for ADAMTS15 (Q8TE58 ) (see all 10 )ADAMTS15 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_620686.1 ENSEMBL proteins: ENSP00000299164 Human Recombinant Protein Products for ADAMTS15: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005578 proteinaceous extracellular matrix
IEA --
ADAMTS15 for ontologies About GeneDecksing ADAMTS15 Antibody Products: Assay Products for ADAMTS15:
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Protein
Domains / Familiesfor ADAMTS15 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ADAMTS15 for domains About GeneDecksing 5/7 InterPro domains/families (see all 7 ):
Graphical View of Domain Structure for InterPro Entry Q8TE58 ProtoNet protein and cluster: Q8TE58
5 Blocks protein families : IPB000884 Thrombospondin IPB001762 Disintegrin IPB002870 Metalloendopeptidase M12B IPB008085 Thrombospondin type 1 repeat signature IPB010294 ADAM-TS Spacer 1 UniProtKB/Swiss-Prot: ATS15_HUMAN, Q8TE58 Domain : The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellularmatrix (By similarity) Domain : The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting theenzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme Similarity : Contains 1 disintegrin domainSimilarity : Contains 1 peptidase M12B domainSimilarity : Contains 3 TSP type-1 domains
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Functionfor ADAMTS15 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Enzyme Numbers (IUBMB): EC 3.4.24.- 1 EC 3.4.24.14 2 EC 3.4.24.82 2 EC 3.4.24 2 Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0004222 metalloendopeptidase activity
IEA -- GO:0008270 zinc ion binding
IEA --
ADAMTS15 for ontologies About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ADAMTS15 (NM_139055 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADAMTS15 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADAMTS15
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS15
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Pathways & Interactionsfor ADAMTS15 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ADAMTS15 Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006508 proteolysis
IEA --
ADAMTS15 for ontologies About GeneDecksing
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Drugs & Compoundsfor ADAMTS15 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ADAMTS15 Search CenterWatch for drugs/clinical trials and news about ADAMTS15 / ATS15
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Transcriptsfor ADAMTS15 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ADAMTS15 gene: NM_139055.2 Unigene Cluster for ADAMTS15:
ADAM metallopeptidase with thrombospondin type 1 motif, 15 Hs.534221 [show with all ESTs ] Unigene Representative Sequence: NM_139055 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000299164 (uc010scd.2 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ADAMTS15 (NM_139055 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADAMTS15 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADAMTS15
Additional cDNA sequence: AJ315733.1 AK123049.1 AK130067.1 BC109114.1
4 DOTS entries : DT.412703 DT.101975133
DT.97822376 DT.99999236 3 AceView cDNA sequences :
NM_139055 AJ315733 CF994242 GeneLoc Exon Structure
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Expression for ADAMTS15 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ADAMTS15 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image ADAMTS15 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See ADAMTS15 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ADAMTS15 SOURCE GeneReport for Unigene cluster: Hs.534221 UniProtKB/Swiss-Prot: ATS15_HUMAN, Q8TE58 Tissue specificity : Expressed in fetal liver and kidney, but not in any of the adult tissues examined SABiosciences Custom PCR Arrays for ADAMTS15 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ADAMTS15Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ADAMTS15 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ADAMTS15 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ADAMTS15 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS15
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Orthologsfor ADAMTS15 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for ADAMTS15 gene from 6/19 species (see all 19 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
ADAMTS151
ADAM metallopeptidase with thrombospondin type 1 motif, more
76.21(n) 77.98(a)
 
419733 XM_417874.3 XP_417874.2
lizard (Anolis carolinensis)
Reptilia
ADAMTS156
--
73(a)
1 ↔ 1
GL343197.1(433549-467281)
tropical clawed frog (Xenopus tropicalis)
Amphibia
Str.135142
Transcribed sequence with weak similarity to protein more
75.22(n)
 
BX734088.1
zebrafish (Danio rerio)
Actinopterygii
LOC1000020591
A disintegrin and metalloproteinase with thrombospondin more
65.07(n) 66.78(a)
 
100002059 XM_001341899.1 XP_001341935.1
fruit fly (Drosophila melanogaster)
Insecta
CG148696
--
16(a)
1 → many
3R(11267965-11301915)
worm (Caenorhabditis elegans)
Secernentea
gon-16 mig-176
ADAM family mig-17
16(a) 15(a)
1 ↔ manypossible ortholog
IV(9935046-9945754) V(11446634-11449228)
ENSEMBL Gene Tree for ADAMTS15 (if available)TreeFam Gene Tree for ADAMTS15 (if available)
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Paralogsfor ADAMTS15 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ADAMTS15 gene ADAMTS17 2 ADAMTS18 2 ADAMTS6 2 ADAMTS12 2 ADAMTS20 2 ADAMTS5 2 ADAMTS4 2 ADAMTS9 2 ADAMTS16 2 ADAMTS10 2 ADAMTS7 2 ADAMTS1 2 ADAMTS19 2 ADAMTS14 2 ADAMTS2 2 ADAMTS8 2 ADAMTS3 2 12 SIMAP similar genes for ADAMTS15 using alignment to 1 protein entry: ATS15_HUMAN :TSHZ2 ADAMTS8 ADAMTS1 DKFZp686E01144 ADAMTS4 ADAMTS5 ADAMTS20 ADAMTS9 ADAMTS6 ADAMTS12 ADAMTS14 ADAMTS2
ADAMTS15 for paralogs About GeneDecksing
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Genomic Variantsfor ADAMTS15 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 11 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ADAMTS15 (130318869 - 130346539 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ADAMTS15 2 CNVs : 3869 30569
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ADAMTS15
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Disorders
/ Diseasesfor ADAMTS15 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ADAMTS15 for disorders About GeneDecksing
OMIM gene information: 607509
OMIM disorders : --6 diseases for ADAMTS15 : About MalaCards chondrosarcoma breast carcinoma colorectal cancer asthma carcinoma prostatitis Export disorders for ADAMTS15 gene to outside databases
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Publicationsfor ADAMTS15 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ADAMTS15 gene, integrated from 9 sources (see all 12 ): (articles sorted by number of sources associating them with ADAMTS15) Utopia : connect your pdf to the dynamic world of online information
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. (PubMed id 11867212) 1 , 2 , 3 Cal S....Lopez-Otin C. (2002) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Genetic inactivation of ADAMTS15 metalloprotease in h uman colorectal cancer. (PubMed id 19458070) 1 , 9 Viloria C.G....LA^pez-OtA-n C. (2009) Androgen regulates ADAMTS15 gene expression in prosta te cancer cells. (PubMed id 20590445) 1 Molokwu C.N....Buttle D.J. (2010) ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma. (PubMed id 16152618) 1 Porter S....Edwards D.R. (2006) The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974) 2 Sjoeblom T.... Velculescu V.E. (2006) The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican. (PubMed id 15599946) 1 Cross N.A....Eaton C.L. (2005) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Expression profiles and clinical correlations of degr adome components in the tumor microenvironment of head and neck squamous cell c arcinoma. (PubMed id 20305301) 9 Stokes A....KAohAori V.M. (2010) Expression of ADAMs and their inhibitors in sputum from patients with asthma. (PubMed id 17088949) 9 Paulissen G....Cataldo D.D. (2006)
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External Searches for ADAMTS15 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ADAMTS15 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ADAMTS15 gene
(According to HUGE )
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Specialized Databases showing ADAMTS15 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for ADAMTS15 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ADAMTS15 gene: Search GeneIP for patents involving ADAMTS15 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ADAMTS15 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ADAMTS15 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ADAMTS15 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ADAMTS15 OriGene Protein Over-expression Lysate for ADAMTS15 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ADAMTS15 OriGene 3'-UTR Clone for ADAMTS15 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ADAMTS15 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ADAMTS15 OriGene Custom Protein Services for ADAMTS15 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADAMTS15 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ADAMTS15 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ADAMTS15 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ADAMTS15 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ADAMTS15 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ADAMTS15
ADAMTS15 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAMTS15
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ADAMTS15
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