Aliases for ADAM9 Gene
External Ids for ADAM9 Gene
Previous Symbols for ADAM9 Gene
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
GeneCards Summary for ADAM9 Gene
ADAM9 (ADAM Metallopeptidase Domain 9) is a Protein Coding gene. Diseases associated with ADAM9 include cone-rod dystrophy 9 and myeloma. Among its related pathways are Degradation of the extracellular matrix and Cytoskeletal Signaling. GO annotations related to this gene include SH3 domain binding and integrin binding. An important paralog of this gene is ADAM33.
UniProtKB/Swiss-Prot for ADAM9 Gene
Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP.