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Aliases for ADAM6 Gene

Aliases for ADAM6 Gene

  • ADAM Metallopeptidase Domain 6 (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 6 2 3
  • Metalloprotease-Like, Disintegrin-Like Protein Pseudogene 3
  • ADAM Metallopeptidase Domain 6, Pseudogene 2
  • Chromosome 14 Open Reading Frame 96 2
  • ADAM Metallopeptidase Domain 6 2
  • C14orf96 3
  • TMDCIV 3

External Ids for ADAM6 Gene

Previous HGNC Symbols for ADAM6 Gene

  • C14orf96

Previous GeneCards Identifiers for ADAM6 Gene

  • GC00U990447
  • GC14U900437
  • GC14M105506
  • GC14M106435
  • GC14M086568

Summaries for ADAM6 Gene

GeneCards Summary for ADAM6 Gene

ADAM6 (ADAM Metallopeptidase Domain 6 (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM6 Gene

Genomics for ADAM6 Gene

Regulatory Elements for ADAM6 Gene

Enhancers for ADAM6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ADAM6 on UCSC Golden Path with GeneCards custom track

Genomic Location for ADAM6 Gene

Chromosome:
14
Start:
105,969,729 bp from pter
End:
105,972,269 bp from pter
Size:
2,541 bases
Orientation:
Minus strand

Genomic View for ADAM6 Gene

Genes around ADAM6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM6 Gene

Proteins for ADAM6 Gene

Post-translational modifications for ADAM6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM6 Gene

Domains & Families for ADAM6 Gene

Gene Families for ADAM6 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM6: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAM6 Gene

Function for ADAM6 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM6 Gene

Localization for ADAM6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADAM6 Gene

Pathways & Interactions for ADAM6 Gene

SuperPathways for ADAM6 Gene

No Data Available

Interacting Proteins for ADAM6 Gene

Gene Ontology (GO) - Biological Process for ADAM6 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAM6 Gene

Drugs & Compounds for ADAM6 Gene

No Compound Related Data Available

Transcripts for ADAM6 Gene

mRNA/cDNA for ADAM6 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ADAM6 Gene

ADAM metallopeptidase domain 6, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM6 Gene

No ASD Table

Relevant External Links for ADAM6 Gene

GeneLoc Exon Structure for
ADAM6
ECgene alternative splicing isoforms for
ADAM6

Expression for ADAM6 Gene

mRNA expression in normal human tissues for ADAM6 Gene

mRNA differential expression in normal tissues according to GTEx for ADAM6 Gene

This gene is overexpressed in Testis (x52.8).

NURSA nuclear receptor signaling pathways regulating expression of ADAM6 Gene:

ADAM6

SOURCE GeneReport for Unigene cluster for ADAM6 Gene:

Hs.662288
genes like me logo Genes that share expression patterns with ADAM6: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ADAM6 Gene

Orthologs for ADAM6 Gene

Evolution for ADAM6 Gene

ENSEMBL:
Gene Tree for ADAM6 (if available)
TreeFam:
Gene Tree for ADAM6 (if available)

No data available for Orthologs for ADAM6 Gene

Paralogs for ADAM6 Gene

No data available for Paralogs for ADAM6 Gene

Variants for ADAM6 Gene

Sequence variations from dbSNP and Humsavar for ADAM6 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs34417602 -- 105,969,463(+) GAACA(-/G)GGGAG downstream-variant-500B
rs11851990 -- 105,972,039(+) GAGGC(A/G)TAGTG nc-transcript-variant
rs34543930 -- 105,971,404(+) TAAAT(A/T)TAGTA intron-variant
rs34735479 -- 105,971,400(+) AAGAT(-/A)AATAT intron-variant
rs4042128 -- 105,969,445(-) TTCCT(C/T)ACGGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ADAM6 Gene

Variant ID Type Subtype PubMed ID
dgv1982n100 CNV gain 25217958
dgv1985n100 CNV loss 25217958
dgv1995n100 CNV gain 25217958
dgv1996n100 CNV loss 25217958
dgv2004n100 CNV gain 25217958
dgv2005n100 CNV gain 25217958
dgv2012n100 CNV gain 25217958
dgv2013n100 CNV loss 25217958
dgv2014n100 CNV gain 25217958
dgv2015n100 CNV loss 25217958
dgv2016n100 CNV loss 25217958
dgv2017n100 CNV gain 25217958
dgv2018n100 CNV loss 25217958
dgv2019n100 CNV loss 25217958
dgv2020n100 CNV gain 25217958
dgv2021n100 CNV loss 25217958
dgv2022n100 CNV loss 25217958
dgv2023n100 CNV loss 25217958
dgv2024n100 CNV gain+loss 25217958
dgv2025n100 CNV gain 25217958
dgv2026n100 CNV loss 25217958
dgv2027n100 CNV loss 25217958
dgv2028n100 CNV gain 25217958
dgv2029n100 CNV gain 25217958
dgv2031n100 CNV loss 25217958
dgv2032n100 CNV loss 25217958
dgv27n68 CNV gain+loss 17160897
dgv392n67 CNV loss 20364138
dgv394n67 CNV loss 20364138
dgv423e199 CNV deletion 23128226
esv1001368 CNV loss 20482838
esv1002625 CNV gain 20482838
esv27023 CNV gain+loss 19812545
esv2749327 CNV deletion 23290073
esv2749328 CNV deletion 23290073
esv2760346 CNV gain+loss 21179565
esv29981 CNV gain 17803354
esv32669 CNV gain+loss 17666407
esv3568731 CNV gain 25503493
esv3581458 CNV loss 25503493
esv3581459 CNV loss 25503493
esv3581461 CNV loss 25503493
esv3635665 CNV loss 21293372
esv3892583 CNV gain 25118596
esv3892584 CNV gain 25118596
esv3892585 CNV gain 25118596
nsv1036179 CNV gain+loss 25217958
nsv1039720 CNV gain 25217958
nsv1047682 CNV gain+loss 25217958
nsv1048883 CNV loss 25217958
nsv1050165 CNV gain+loss 25217958
nsv1052391 CNV gain 25217958
nsv1052873 CNV gain+loss 25217958
nsv1053673 CNV loss 25217958
nsv1054255 CNV loss 25217958
nsv1443 CNV deletion 18451855
nsv436179 CNV deletion 17901297
nsv436184 CNV deletion 17901297
nsv456477 CNV loss 19166990
nsv471673 CNV gain+loss 15918152
nsv511038 OTHER complex 20534489
nsv511534 CNV gain 21212237
nsv517055 CNV gain+loss 19592680
nsv566351 CNV loss 21841781
nsv566486 CNV loss 21841781
nsv817649 CNV loss 17921354
nsv819133 CNV gain 19587683
nsv821677 CNV gain 15273396
nsv827099 CNV loss 20364138
nsv827138 CNV loss 20364138
nsv827147 CNV loss 20364138
nsv827155 CNV loss 20364138
nsv832895 CNV gain+loss 17160897
nsv974376 CNV duplication 23825009
nsv974377 CNV duplication 23825009
nsv976376 CNV duplication 23825009
nsv977508 CNV duplication 23825009

Relevant External Links for ADAM6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAM6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADAM6 Gene

Disorders for ADAM6 Gene

Relevant External Links for ADAM6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADAM6

No disorders were found for ADAM6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM6 Gene

Publications for ADAM6 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  2. Comparative genomic analysis of human and chimpanzee proteases. (PMID: 16162398) Puente X.S. … LA^pez-OtA-n C. (Genomics 2005) 3 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 65
  4. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3 65

Products for ADAM6 Gene

Sources for ADAM6 Gene

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